Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 11, 2015, Pages 3570-3575

  Xie, Kabin ^a   Minkenberg, Bastian ^a   Yang, Yinong ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

CRISPR Cas9; Genome editing; Multiplex; tRNA processing

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; MITOGEN ACTIVATED PROTEIN KINASE; RIBONUCLEASE P; SYNTHETIC DNA; TRANSFER RNA; GUIDE RNA;

5' UNTRANSLATED REGION; ARTICLE; BLEACHING; CHROMOSOME; CRISPR CAS SYSTEM; DNA END JOINING REPAIR; ENHANCER REGION; GENE EXPRESSION; GENE SEQUENCE; NONHUMAN; PLANT GENOME; PRIORITY JOURNAL; PROMOTER REGION; PROTOPLAST; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RICE; RNA EDITING; SEQUENCE ANALYSIS; TANDEM REPEAT; TRANSGENIC PLANT; GENETIC ENGINEERING; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; MUTATION; NUCLEOTIDE SEQUENCE; ORYZA; PLANT GENE; RNA PROCESSING;

BASE SEQUENCE; CRISPR-CAS SYSTEMS; GENES, PLANT; GENETIC ENGINEERING; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; ORYZA; PLANTS, GENETICALLY MODIFIED; PROTOPLASTS; RNA EDITING; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, GUIDE; RNA, TRANSFER;

EID: 84925262435     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1420294112     Document Type: Article

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