1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases

ChemMedChem

Volumn 12, Issue 12, 2017, Pages 972-985

  Sevaille, Laurent ^a   Gavara, Laurent ^a   Bebrone, Carine ^b,j   De Luca, Filomena ^c   Nauton, Lionel ^d,k   Achard, Maud ^e,l   Mercuri, Paola ^b   Tanfoni, Silvia ^c   Borgianni, Luisa ^c   Guyon, Carole ^a   Lonjon, Pauline ^a,m   Turan Zitouni, Gülhan ^f   Dzieciolowski, Julia ^g   Becker, Katja ^g   Bénard, Lionel ^h   Condon, Ciaran ⁱ   Maillard, Ludovic ^a   Martinez, Jean ^a   Frère, Jean Marie ^b   Dideberg, Otto ^d   Galleni, Moreno ^b   Docquier, Jean Denis ^c   Hernandez, Jean François ^a   more..

^a UNIVERSITÉ DE MONTPELLIER   (France)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITY OF SIENA   (Italy)

^d INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^e EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^f ANADOLU UNIVERSITY   (Turkey)

^g JUSTUS LIEBIG UNIVERSITY   (Germany)

^h Institut de Biologie Physico Chimique   (France)

ⁱ EGM   (France)

^j Symbiose Biomaterials   (Belgium)

^k UNIVERSITÉ CLERMONT AUVERGNE   (France)

^l UNIVERSITY OF QUEENSLAND   (Australia)

^m CERN   (Switzerland)

more..

Author keywords

antibiotics; bacterial resistance; lactams; metalloenzymes; nitrogen heterocycles

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; BETA LACTAMASE INHIBITOR; BICYCLO COMPOUND; ENDONUCLEASE; HALOGEN; HYDROLASE; HYDROXYACYLGLUTATHIONE HYDROLASE; IMP 1 PROTEIN; METALLO BETA LACTAMASE; NDM 1 PROTEIN; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; RIBONUCLEASE; UNCLASSIFIED DRUG; VIM 2 PROTEIN; VIM 4 PROTEIN; ZINC; BETA LACTAMASE; THIOKETONE; TRIAZOLE DERIVATIVE;

ANTIBIOTIC RESISTANCE; ARTICLE; COMPLEX FORMATION; CRYSTALLOGRAPHY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; IC50; NONHUMAN; PRIORITY JOURNAL; AEROMONAS HYDROPHILA; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; ENZYMOLOGY; METABOLISM; STENOTROPHOMONAS MALTOPHILIA; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AEROMONAS HYDROPHILA; BETA-LACTAMASE INHIBITORS; BETA-LACTAMASES; DOSE-RESPONSE RELATIONSHIP, DRUG; MOLECULAR STRUCTURE; STENOTROPHOMONAS MALTOPHILIA; STRUCTURE-ACTIVITY RELATIONSHIP; THIONES; TRIAZOLES;

EID: 85020428257     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201700186     Document Type: Article

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