A metallo-β-lactamase enzyme in action: Crystal structures of the monozinc carbapenemase CphA and its complex with biapenem

Journal of Molecular Biology

Volumn 345, Issue 4, 2005, Pages 785-795

  Garau, Gianpiero ^a   Bebrone, Carine ^b   Anne, Christine ^b   Galleni, Moreno ^b   Frère, Jean Marie ^b   Dideberg, Otto ^a  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

3D structure; antibiotic resistance; drug design; enzymatic mechanism; X ray crystallography

Indexed keywords

BACTERIAL PROTEIN; BETA LACTAMASE; BIAPENEM; CARBAPENEM; PROTEIN CPHA; UNCLASSIFIED DRUG; ZINC; ZINC ION;

AEROMONAS HYDROPHILA; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; HYDROLYSIS; MODEL; MUTANT; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ANALYSIS; WILD TYPE; X RAY ANALYSIS;

AEROMONAS; AEROMONAS HYDROPHILA;

EID: 10044225894     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.10.070     Document Type: Article

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