Connectivity between catalytic landscapes of the metallo-β-lactamase superfamily

Journal of Molecular Biology

Volumn 426, Issue 13, 2014, Pages 2442-2456

  Baier, Florian ^a   Tokuriki, Nobuhiko ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

catalytic landscape; catalytic promiscuity; enzyme evolution; enzyme superfamily

Indexed keywords

ARYLSULFATASE; GLUCONOLACTONASE; METALLO BETA LACTAMASE; PHOSPHODIESTERASE; PHOSPHOTRIESTERASE;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL REACTION; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBSTRATE; EVOLUTION; HYDROPHOBICITY; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT;

CATALYTIC LANDSCAPE; CATALYTIC PROMISCUITY; ENZYME EVOLUTION; ENZYME SUPERFAMILY;

BETA-LACTAMASES; CATALYTIC DOMAIN; DATABASES, PROTEIN; EVOLUTION, MOLECULAR; KINETICS; MODELS, MOLECULAR; PHYLOGENY; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT;

EID: 84901807720     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2014.04.013     Document Type: Article

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