Cycloheximide inhibits starvation-induced autophagy through mTORC1 activation

Biochemical and Biophysical Research Communications

Volumn 445, Issue 2, 2014, Pages 334-339

  Watanabe Asano, Takako ^a   Kuma, Akiko ^a,b,c   Mizushima, Noboru ^a,b  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Autophagy; Cycloheximide; mTORC1; Protein degradation; Protein synthesis

Indexed keywords

CYCLOHEXIMIDE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; AUTOPHAGY; CELL STRAIN HEK293; DRUG MECHANISM; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; STARVATION;

AUTOPHAGY; CYCLOHEXIMIDE; MTORC1; PROTEIN DEGRADATION; PROTEIN SYNTHESIS;

ANIMALS; AUTOPHAGY; CELL LINE; CYCLOHEXIMIDE; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; MICE; MULTIPROTEIN COMPLEXES; NAPHTHYRIDINES; PROTEIN BIOSYNTHESIS; PROTEIN SYNTHESIS INHIBITORS; STARVATION; TOR SERINE-THREONINE KINASES;

EID: 84896089543     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.01.180     Document Type: Article

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