-
1
-
-
84911417634
-
Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiation
-
Senyo, S. E., Lee, R. T. & Kühn, B. Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiation. Stem Cell Res. 13, 532-541 (2014).
-
(2014)
Stem Cell Res.
, vol.13
, pp. 532-541
-
-
Senyo, S.E.1
Lee, R.T.2
Kühn, B.3
-
2
-
-
34249714158
-
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
-
Nakai, A. et al. The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat. Med. 13, 619-624 (2007).
-
(2007)
Nat. Med.
, vol.13
, pp. 619-624
-
-
Nakai, A.1
-
3
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
Kuma, A. et al. The role of autophagy during the early neonatal starvation period. Nature 432, 1032-1036 (2004).
-
(2004)
Nature
, vol.432
, pp. 1032-1036
-
-
Kuma, A.1
-
4
-
-
84885543075
-
Myocardial glycophagy - A specific glycogen handling response to metabolic stress is accentuated in the female heart
-
Reichelt, M. E., Mellor, K. M., Curl, C. L., Stapleton, D. & Delbridge, L. M. Myocardial glycophagy - a specific glycogen handling response to metabolic stress is accentuated in the female heart. J. Mol. Cell. Cardiol. 65, 67-75 (2013).
-
(2013)
J. Mol. Cell. Cardiol.
, vol.65
, pp. 67-75
-
-
Reichelt, M.E.1
Mellor, K.M.2
Curl, C.L.3
Stapleton, D.4
Delbridge, L.M.5
-
5
-
-
84859161154
-
Microautophagy: Lesser-known self-eating
-
Li, W. W., Li, J. & Bao, J. K. Microautophagy: lesser-known self-eating. Cell. Mol. Life Sci. 69, 1125-1136 (2012).
-
(2012)
Cell. Mol. Life Sci.
, vol.69
, pp. 1125-1136
-
-
Li, W.W.1
Li, J.2
Bao, J.K.3
-
6
-
-
85013413636
-
Cellular proteostasis: Degradation of misfolded proteins by lysosomes
-
Jackson, M. P. & Hewitt, E. W. Cellular proteostasis: degradation of misfolded proteins by lysosomes. Essays Biochem. 60, 173-180 (2016).
-
(2016)
Essays Biochem.
, vol.60
, pp. 173-180
-
-
Jackson, M.P.1
Hewitt, E.W.2
-
7
-
-
78651423598
-
Microautophagy of cytosolic proteins by late endosomes
-
Sahu, R. et al. Microautophagy of cytosolic proteins by late endosomes. Dev. Cell 20, 131-139 (2011).
-
(2011)
Dev. Cell
, vol.20
, pp. 131-139
-
-
Sahu, R.1
-
8
-
-
84979298961
-
Formation of mitochondrial-derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system
-
Cadete, V. J. et al. Formation of mitochondrial-derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system. J. Physiol. 594, 5343-5362 (2016).
-
(2016)
J. Physiol.
, vol.594
, pp. 5343-5362
-
-
Cadete, V.J.1
-
9
-
-
78650328444
-
Autophagy basics
-
Tanida, I. Autophagy basics. Microbiol. Immunol. 55, 1-11 (2011).
-
(2011)
Microbiol. Immunol.
, vol.55
, pp. 1-11
-
-
Tanida, I.1
-
10
-
-
77956414236
-
The origin of the autophagosomal membrane
-
Tooze, S. A. & Yoshimori, T. The origin of the autophagosomal membrane. Nat. Cell Biol. 12, 831-835 (2010).
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 831-835
-
-
Tooze, S.A.1
Yoshimori, T.2
-
11
-
-
84962920372
-
Regulation of autophagy by Beclin 1 in the heart
-
Maejima, Y., Isobe, M. & Sadoshima, J. Regulation of autophagy by Beclin 1 in the heart. J. Mol. Cell. Cardiol. 95, 19-25 (2016).
-
(2016)
J. Mol. Cell. Cardiol.
, vol.95
, pp. 19-25
-
-
Maejima, Y.1
Isobe, M.2
Sadoshima, J.3
-
12
-
-
85013763791
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
(3rd edition)
-
Klionsky, D. J. et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12, 1-222 (2016).
-
(2016)
Autophagy
, vol.12
, pp. 1-222
-
-
Klionsky, D.J.1
-
13
-
-
70349687405
-
Discovery of Atg5/Atg7-independent alternative macroautophagy
-
Nishida, Y. et al. Discovery of Atg5/Atg7-independent alternative macroautophagy. Nature 461, 654-658 (2009).
-
(2009)
Nature
, vol.461
, pp. 654-658
-
-
Nishida, Y.1
-
14
-
-
77954237882
-
Network organization of the human autophagy system
-
Behrends, C., Sowa, M. E., Gygi, S. P. & Harper, J. W. Network organization of the human autophagy system. Nature 466, 68-76 (2010).
-
(2010)
Nature
, vol.466
, pp. 68-76
-
-
Behrends, C.1
Sowa, M.E.2
Gygi, S.P.3
Harper, J.W.4
-
15
-
-
84955594709
-
Lysosomal signaling in control of degradation pathways
-
Huber, L. A. & Teis, D. Lysosomal signaling in control of degradation pathways. Curr. Opin. Cell Biol. 39, 8-14 (2016).
-
(2016)
Curr. Opin. Cell Biol.
, vol.39
, pp. 8-14
-
-
Huber, L.A.1
Teis, D.2
-
16
-
-
84870880174
-
The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes
-
Itakura, E., Kishi-Itakura, C. & Mizushima, N. The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. Cell 151, 1256-1269 (2012).
-
(2012)
Cell
, vol.151
, pp. 1256-1269
-
-
Itakura, E.1
Kishi-Itakura, C.2
Mizushima, N.3
-
17
-
-
33845407202
-
Atg22 recycles amino acids to link the degradative and recycling functions of autophagy
-
Yang, Z., Huang, J., Geng, J., Nair, U. & Klionsky, D. J. Atg22 recycles amino acids to link the degradative and recycling functions of autophagy. Mol. Biol. Cell 17, 5094-5104 (2006).
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 5094-5104
-
-
Yang, Z.1
Huang, J.2
Geng, J.3
Nair, U.4
Klionsky, D.J.5
-
18
-
-
84927633547
-
Untangling autophagy measurements: All fluxed up
-
Gottlieb, R. A., Andres, A. M., Sin, J. & Taylor, D. P. Untangling autophagy measurements: all fluxed up. Circ. Res. 116, 504-514 (2015).
-
(2015)
Circ. Res.
, vol.116
, pp. 504-514
-
-
Gottlieb, R.A.1
Andres, A.M.2
Sin, J.3
Taylor, D.P.4
-
19
-
-
84955397156
-
Measuring cardiac autophagic flux in vitro and in vivo
-
Gurney, M. A. et al. Measuring cardiac autophagic flux in vitro and in vivo. Methods Mol. Biol. 1219, 187-197 (2015).
-
(2015)
Methods Mol. Biol.
, vol.1219
, pp. 187-197
-
-
Gurney, M.A.1
-
20
-
-
84926609445
-
Autophagy and ubiquitination in cardiovascular diseases
-
Martins-Marques, T., Ribeiro-Rodrigues, T., Pereira, P., Codogno, P. & Girao, H. Autophagy and ubiquitination in cardiovascular diseases. DNA Cell Biol. 34, 243-251 (2015).
-
(2015)
DNA Cell Biol.
, vol.34
, pp. 243-251
-
-
Martins-Marques, T.1
Ribeiro-Rodrigues, T.2
Pereira, P.3
Codogno, P.4
Girao, H.5
-
21
-
-
84876085831
-
Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates
-
Korac, J. et al. Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates. J. Cell Sci. 126, 580-592 (2013).
-
(2013)
J. Cell Sci.
, vol.126
, pp. 580-592
-
-
Korac, J.1
-
22
-
-
84957837273
-
Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals
-
Tan, V. P. & Miyamoto, S. Nutrient-sensing mTORC1: integration of metabolic and autophagic signals. J. Mol. Cell. Cardiol. 95, 31-41 (2016).
-
(2016)
J. Mol. Cell. Cardiol.
, vol.95
, pp. 31-41
-
-
Tan, V.P.1
Miyamoto, S.2
-
23
-
-
80053476420
-
The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR
-
Egan, D., Kim, J., Shaw, R. J. & Guan, K. L. The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR. Autophagy 7, 643-644 (2011).
-
(2011)
Autophagy
, vol.7
, pp. 643-644
-
-
Egan, D.1
Kim, J.2
Shaw, R.J.3
Guan, K.L.4
-
24
-
-
84864874958
-
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
-
Martina, J. A., Chen, Y., Gucek, M. & Puertollano, R. MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB. Autophagy 8, 903-914 (2012).
-
(2012)
Autophagy
, vol.8
, pp. 903-914
-
-
Martina, J.A.1
Chen, Y.2
Gucek, M.3
Puertollano, R.4
-
25
-
-
84888839943
-
Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading
-
Oyabu, J. et al. Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading. Biochem. Biophys. Res. Commun. 441, 787-792 (2013).
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.441
, pp. 787-792
-
-
Oyabu, J.1
-
26
-
-
84875360924
-
RalGDS-dependent cardiomyocyte autophagy is required for load-induced ventricular hypertrophy
-
Rifki, O. F., Bodemann, B. O., Battiprolu, P. K., White, M. A. & Hill, J. A. RalGDS-dependent cardiomyocyte autophagy is required for load-induced ventricular hypertrophy. J. Mol. Cell. Cardiol. 59, 128-138 (2013).
-
(2013)
J. Mol. Cell. Cardiol.
, vol.59
, pp. 128-138
-
-
Rifki, O.F.1
Bodemann, B.O.2
Battiprolu, P.K.3
White, M.A.4
Hill, J.A.5
-
27
-
-
79952775153
-
Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy
-
Cao, D. J. et al. Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy. Proc. Natl Acad. Sci. USA 108, 4123-4128 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 4123-4128
-
-
Cao, D.J.1
-
28
-
-
84860705893
-
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure
-
Oka, T. et al. Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure. Nature 485, 251-255 (2012).
-
(2012)
Nature
, vol.485
, pp. 251-255
-
-
Oka, T.1
-
29
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
Shimada, K. et al. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity 36, 401-414 (2012).
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
-
30
-
-
84921985434
-
Endogenous Drp1 mediates mitochondrial autophagy and protects the heart against energy stress
-
Ikeda, Y. et al. Endogenous Drp1 mediates mitochondrial autophagy and protects the heart against energy stress. Circ. Res. 116, 264-278 (2015).
-
(2015)
Circ. Res.
, vol.116
, pp. 264-278
-
-
Ikeda, Y.1
-
31
-
-
77953704724
-
Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells
-
Carreira, R. S., Lee, Y., Ghochani, M., Gustafsson, A. B. & Gottlieb, R. A. Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells. Autophagy 6, 462-472 (2010).
-
(2010)
Autophagy
, vol.6
, pp. 462-472
-
-
Carreira, R.S.1
Lee, Y.2
Ghochani, M.3
Gustafsson, A.B.4
Gottlieb, R.A.5
-
32
-
-
84922776083
-
PINK1/Parkin-mediated mitophagy in mammalian cells
-
Eiyama, A. & Okamoto, K. PINK1/Parkin-mediated mitophagy in mammalian cells. Curr. Opin. Cell Biol. 33, 95-101 (2015).
-
(2015)
Curr. Opin. Cell Biol.
, vol.33
, pp. 95-101
-
-
Eiyama, A.1
Okamoto, K.2
-
33
-
-
84964627159
-
Mitochondrial remodeling: Rearranging, recycling, and reprogramming
-
Gottlieb, R. A. & Bernstein, D. Mitochondrial remodeling: rearranging, recycling, and reprogramming. Cell Calcium 60, 88-101 (2016).
-
(2016)
Cell Calcium
, vol.60
, pp. 88-101
-
-
Gottlieb, R.A.1
Bernstein, D.2
-
34
-
-
84935008216
-
The molecular mechanisms of mitochondrial autophagy/mitophagy in the heart
-
Saito, T. & Sadoshima, J. The molecular mechanisms of mitochondrial autophagy/mitophagy in the heart. Circ. Res. 116, 1477-1490 (2015).
-
(2015)
Circ. Res.
, vol.116
, pp. 1477-1490
-
-
Saito, T.1
Sadoshima, J.2
-
35
-
-
84951930787
-
The PINK1-PARKIN mitochondrial ubiquitylation pathway drives a program of OPTN/ NDP52 recruitment and TBK1 activation to promote mitophagy
-
Heo, J.-M., Ordureau, A., Paulo, J. A., Rinehart, J. & Harper, J. W. The PINK1-PARKIN mitochondrial ubiquitylation pathway drives a program of OPTN/ NDP52 recruitment and TBK1 activation to promote mitophagy. Mol. Cell 60, 7-20 (2015).
-
(2015)
Mol. Cell
, vol.60
, pp. 7-20
-
-
Heo, J.-M.1
Ordureau, A.2
Paulo, J.A.3
Rinehart, J.4
Harper, J.W.5
-
36
-
-
84939804206
-
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
-
Lazarou, M. et al. The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy. Nature 524, 309-314 (2015).
-
(2015)
Nature
, vol.524
, pp. 309-314
-
-
Lazarou, M.1
-
37
-
-
84979265884
-
Defending the mitochondria: The pathways of mitophagy and mitochondrial-derived vesicles
-
Roberts, R. F., Tang, M. Y., Fon, E. A. & Durcan, T. M. Defending the mitochondria: the pathways of mitophagy and mitochondrial-derived vesicles. Int. J. Biochem. Cell Biol. 79, 427-436 (2016).
-
(2016)
Int. J. Biochem. Cell Biol.
, vol.79
, pp. 427-436
-
-
Roberts, R.F.1
Tang, M.Y.2
Fon, E.A.3
Durcan, T.M.4
-
38
-
-
85020672890
-
Mitochondrial-derived vesicle formation in cardiac mitochondrial quality control [abstract]
-
Cadete, V. et al. Mitochondrial-derived vesicle formation in cardiac mitochondrial quality control [abstract]. FASEB J. 29 (Suppl.), 1036.1 (2015).
-
(2015)
FASEB J.
, vol.29
, pp. 10361
-
-
Cadete, V.1
-
39
-
-
79958172986
-
Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1
-
Huang, C. et al. Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1. PLoS ONE 6, e20975 (2011).
-
(2011)
PLoS ONE
, vol.6
, pp. e20975
-
-
Huang, C.1
-
40
-
-
33749433230
-
Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation
-
Brennan, J. P. et al. Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation. Cardiovasc. Res. 72, 313-321 (2006).
-
(2006)
Cardiovasc. Res.
, vol.72
, pp. 313-321
-
-
Brennan, J.P.1
-
41
-
-
0034044807
-
Dinitrophenol, cyclosporin A, and trimetazidine modulate preconditioning in the isolated rat heart: Support for a mitochondrial role in cardioprotection
-
Minners, J. et al. Dinitrophenol, cyclosporin A, and trimetazidine modulate preconditioning in the isolated rat heart: support for a mitochondrial role in cardioprotection. Cardiovasc. Res. 47, 68-73 (2000).
-
(2000)
Cardiovasc. Res.
, vol.47
, pp. 68-73
-
-
Minners, J.1
-
42
-
-
84913546616
-
Mitophagy is required for acute cardioprotection by simvastatin
-
Andres, A. M. et al. Mitophagy is required for acute cardioprotection by simvastatin. Antioxid. Redox Signal. 21, 1960-1973 (2014).
-
(2014)
Antioxid. Redox Signal.
, vol.21
, pp. 1960-1973
-
-
Andres, A.M.1
-
43
-
-
84949663455
-
α-MHC MitoTimer mouse: In vivo mitochondrial turnover model reveals remarkable mitochondrial heterogeneity in the heart
-
Stotland, A. & Gottlieb, R. A. α-MHC MitoTimer mouse: in vivo mitochondrial turnover model reveals remarkable mitochondrial heterogeneity in the heart. J. Mol. Cell. Cardiol. 90, 53-58 (2016).
-
(2016)
J. Mol. Cell. Cardiol.
, vol.90
, pp. 53-58
-
-
Stotland, A.1
Gottlieb, R.A.2
-
44
-
-
84979966353
-
Mito-QC illuminates mitophagy and mitochondrial architecture. In Vivo
-
McWilliams, T. G. & Prescott, A. R. mito-QC illuminates mitophagy and mitochondrial architecture in vivo. J. Cell Biol. 214, 333-345 (2016).
-
(2016)
J. Cell Biol.
, vol.214
, pp. 333-345
-
-
McWilliams, T.G.1
Prescott, A.R.2
-
45
-
-
84947802088
-
Measuring in vivo mitophagy
-
Sun, N. et al. Measuring in vivo mitophagy. Mol. Cell 60, 685-696 (2015).
-
(2015)
Mol. Cell
, vol.60
, pp. 685-696
-
-
Sun, N.1
-
46
-
-
0000314638
-
Over idiopathische hypertrophie van het hart [in Dutch]
-
Pompe, J. C. Over idiopathische hypertrophie van het hart [in Dutch]. Ned. Tijdschr. Geneeskd. 76, 304-312 (1932).
-
(1932)
Ned. Tijdschr. Geneeskd.
, vol.76
, pp. 304-312
-
-
Pompe, J.C.1
-
47
-
-
73649187940
-
α-glucosidase deficiency in generalized glycogenstorage disease (Pompe's disease)
-
Hers, H. G. á-glucosidase deficiency in generalized glycogenstorage disease (Pompe's disease). Biochem. J. 86, 11-16 (1963).
-
(1963)
Biochem. J.
, vol.86
, pp. 11-16
-
-
Hers, H.G.1
-
48
-
-
78049409236
-
Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism
-
Jiang, S. et al. Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism. J. Biol. Chem. 285, 34960-34971 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 34960-34971
-
-
Jiang, S.1
-
49
-
-
80053338210
-
Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1
-
Jiang, S., Wells, C. D. & Roach, P. J. Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1. Biochem. Biophys. Res. Commun. 413, 420-425 (2011).
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.413
, pp. 420-425
-
-
Jiang, S.1
Wells, C.D.2
Roach, P.J.3
-
50
-
-
84900822951
-
Cardiomyocyte glycophagy is regulated by insulin and exposure to high extracellular glucose
-
Mellor, K. M., Varma, U., Stapleton, D. & Delbridge, L. M. D. Cardiomyocyte glycophagy is regulated by insulin and exposure to high extracellular glucose. Am. J. Physiol. Heart Circ. Physiol. 306, H1240-H1245 (2014).
-
(2014)
Am. J. Physiol. Heart Circ. Physiol.
, vol.306
, pp. H1240-H1245
-
-
Mellor, K.M.1
Varma, U.2
Stapleton, D.3
Delbridge, L.M.D.4
-
51
-
-
0345742550
-
An electron microscopic and biochemical study of the effects of glucagon on glycogen autophagy in the liver and heart of newborn rats
-
Kondomerkos, D. J., Kalamidas, S. A. & Kotoulas, O. B. An electron microscopic and biochemical study of the effects of glucagon on glycogen autophagy in the liver and heart of newborn rats. Microsc. Res. Tech. 63, 87-93 (2004).
-
(2004)
Microsc. Res. Tech.
, vol.63
, pp. 87-93
-
-
Kondomerkos, D.J.1
Kalamidas, S.A.2
Kotoulas, O.B.3
-
52
-
-
21644475161
-
Glycogen autophagy in the liver and heart of newborn rats. The effects of glucagon, adrenalin or rapamycin
-
Kondomerkos, D. J., Kalamidas, S. A., Kotoulas, O. B. & Hann, A. C. Glycogen autophagy in the liver and heart of newborn rats. The effects of glucagon, adrenalin or rapamycin. Histol. Histopathol. 20, 689-696 (2005).
-
(2005)
Histol. Histopathol.
, vol.20
, pp. 689-696
-
-
Kondomerkos, D.J.1
Kalamidas, S.A.2
Kotoulas, O.B.3
Hann, A.C.4
-
53
-
-
84889069304
-
Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy
-
Zirin, J., Nieuwenhuis, J. & Perrimon, N. Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy. PLoS Biol. 11, e1001708 (2013).
-
(2013)
PLoS Biol.
, vol.11
, pp. e1001708
-
-
Zirin, J.1
Nieuwenhuis, J.2
Perrimon, N.3
-
54
-
-
84926322618
-
Changing shapes of glycogen-autophagy nexus in neurons: Perspective from a rare epilepsy
-
Singh, P. K. & Singh, S. Changing shapes of glycogen-autophagy nexus in neurons: perspective from a rare epilepsy. Front. Neurol. 6, 14 (2015).
-
(2015)
Front. Neurol.
, vol.6
, pp. 14
-
-
Singh, P.K.1
Singh, S.2
-
55
-
-
77958533750
-
The administration of nonmetabolizable glucose analogues fails to suppress the development of glycogen autophagy in newborn rat hepatocytes
-
Kalamidas, S. A. & Kondomerkos, D. J. The administration of nonmetabolizable glucose analogues fails to suppress the development of glycogen autophagy in newborn rat hepatocytes. Microsc. Res. Tech. 73, 1009-1014 (2010).
-
(2010)
Microsc. Res. Tech.
, vol.73
, pp. 1009-1014
-
-
Kalamidas, S.A.1
Kondomerkos, D.J.2
-
56
-
-
84884902969
-
Polyglucosan neurotoxicity caused by glycogen branching enzyme deficiency can be reversed by inhibition of glycogen synthase
-
Kakhlon, O. et al. Polyglucosan neurotoxicity caused by glycogen branching enzyme deficiency can be reversed by inhibition of glycogen synthase. J. Neurochem. 127, 101-113 (2013).
-
(2013)
J. Neurochem.
, vol.127
, pp. 101-113
-
-
Kakhlon, O.1
-
57
-
-
84901318614
-
Glycogen accumulation underlies neurodegeneration and autophagy impairment in Lafora disease
-
Duran, J., Gruart, A., Garcia-Rocha, M., Delgado-Garcia, J. M. & Guinovart, J. J. Glycogen accumulation underlies neurodegeneration and autophagy impairment in Lafora disease. Hum. Mol. Genet. 23, 3147-3156 (2014).
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 3147-3156
-
-
Duran, J.1
Gruart, A.2
Garcia-Rocha, M.3
Delgado-Garcia, J.M.4
Guinovart, J.J.5
-
58
-
-
84925457539
-
Myocardial glycogen dynamics: New perspectives on disease mechanisms
-
Chandramouli, C. et al. Myocardial glycogen dynamics: new perspectives on disease mechanisms. Clin. Exp. Pharmacol. Physiol. 42, 415-425 (2015).
-
(2015)
Clin. Exp. Pharmacol. Physiol.
, vol.42
, pp. 415-425
-
-
Chandramouli, C.1
-
59
-
-
84863397956
-
Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy
-
Troncoso, R. et al. Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy. Cardiovasc. Res. 93, 320-329 (2012).
-
(2012)
Cardiovasc. Res.
, vol.93
, pp. 320-329
-
-
Troncoso, R.1
-
60
-
-
84890026772
-
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart
-
Riehle, C. et al. Insulin receptor substrate signaling suppresses neonatal autophagy in the heart. J. Clin. Invest. 123, 5319-5333 (2013).
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 5319-5333
-
-
Riehle, C.1
-
61
-
-
84930824983
-
Insulin regulation of myocardial autophagy
-
Riehle, C. & Abel, E. D. Insulin regulation of myocardial autophagy. Circ. J. 78, 2569-2576 (2014).
-
(2014)
Circ. J.
, vol.78
, pp. 2569-2576
-
-
Riehle, C.1
Abel, E.D.2
-
62
-
-
84857914471
-
Rheb is a critical regulator of autophagy during myocardial ischemia: Pathophysiological implications in obesity and metabolic syndrome
-
Sciarretta, S. et al. Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome. Circulation 125, 1134-1146 (2012).
-
(2012)
Circulation
, vol.125
, pp. 1134-1146
-
-
Sciarretta, S.1
-
63
-
-
84887495190
-
Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2
-
Maejima, Y. et al. Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nat. Med. 19, 1478-1488 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 1478-1488
-
-
Maejima, Y.1
-
64
-
-
61849102389
-
DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy
-
Zalckvar, E. et al. DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy. EMBO Rep. 10, 285-292 (2009).
-
(2009)
EMBO Rep.
, vol.10
, pp. 285-292
-
-
Zalckvar, E.1
-
65
-
-
84880777164
-
Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress
-
Gurkar, A. U. et al. Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress. Nat. Commun. 4, 2189 (2013).
-
(2013)
Nat. Commun.
, vol.4
, pp. 2189
-
-
Gurkar, A.U.1
-
66
-
-
44949237240
-
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
-
Wei, Y., Pattingre, S., Sinha, S., Bassik, M. & Levine, B. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol. Cell 30, 678-688 (2008).
-
(2008)
Mol. Cell
, vol.30
, pp. 678-688
-
-
Wei, Y.1
Pattingre, S.2
Sinha, S.3
Bassik, M.4
Levine, B.5
-
67
-
-
84877090221
-
MiR-30a downregulation aggravates pressure overload-induced cardiomyocyte hypertrophy
-
Yin, X. et al. miR-30a downregulation aggravates pressure overload-induced cardiomyocyte hypertrophy. Mol. Cell. Biochem. 379, 1-6 (2013).
-
(2013)
Mol. Cell. Biochem.
, vol.379
, pp. 1-6
-
-
Yin, X.1
-
68
-
-
85008893170
-
MiRNA-30e mediated cardioprotection of ACE2 in rats with doxorubicin-induced heart failure through inhibiting cardiomyocytes autophagy
-
Lai, L., Wang, N., Zhu, G., Duan, X. & Ling, F. MiRNA-30e mediated cardioprotection of ACE2 in rats with doxorubicin-induced heart failure through inhibiting cardiomyocytes autophagy. Life Sci. 169, 69-75 (2017).
-
(2017)
Life Sci.
, vol.169
, pp. 69-75
-
-
Lai, L.1
Wang, N.2
Zhu, G.3
Duan, X.4
Ling, F.5
-
69
-
-
84867009927
-
The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy
-
Ucar, A. et al. The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy. Nat. Commun. 3, 1078 (2012).
-
(2012)
Nat. Commun.
, vol.3
, pp. 1078
-
-
Ucar, A.1
-
70
-
-
84900564532
-
Overexpression of microRNA-99a attenuates heart remodelling and improves cardiac performance after myocardial infarction
-
Li, Q. et al. Overexpression of microRNA-99a attenuates heart remodelling and improves cardiac performance after myocardial infarction. J. Cell. Mol. Med. 18, 919-928 (2014).
-
(2014)
J. Cell. Mol. Med.
, vol.18
, pp. 919-928
-
-
Li, Q.1
-
71
-
-
84973495168
-
MiR-153 regulates apoptosis and autophagy of cardiomyocytes by targeting Mcl-1
-
Zou, Y., Liu, W., Zhang, J. & Xiang, D. miR-153 regulates apoptosis and autophagy of cardiomyocytes by targeting Mcl-1. Mol. Med. Rep. 14, 1033-1039 (2016).
-
(2016)
Mol. Med. Rep.
, vol.14
, pp. 1033-1039
-
-
Zou, Y.1
Liu, W.2
Zhang, J.3
Xiang, D.4
-
72
-
-
84949310237
-
MicroRNA-145 repairs infarcted myocardium by accelerating cardiomyocyte autophagy
-
Higashi, K. et al. MicroRNA-145 repairs infarcted myocardium by accelerating cardiomyocyte autophagy. Am. J. Physiol. Heart Circ. Physiol. 309, H1813-H1826 (2015).
-
(2015)
Am. J. Physiol. Heart Circ. Physiol.
, vol.309
, pp. H1813-H1826
-
-
Higashi, K.1
-
73
-
-
85034454508
-
MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis
-
Cheng, M. et al. MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis. Oncotarget 7, 42274-42287 (2016).
-
(2016)
Oncotarget
, vol.7
, pp. 42274-42287
-
-
Cheng, M.1
-
74
-
-
84992426129
-
MicroRNA-195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1
-
Mo, J., Zhang, D. & Yang, R. MicroRNA-195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1. Biosci. Rep. 36, e00396 (2016).
-
(2016)
Biosci. Rep.
, vol.36
, pp. e00396
-
-
Mo, J.1
Zhang, D.2
Yang, R.3
-
75
-
-
85019690068
-
Roles of exosomes in cardioprotection
-
Barile, L., Moccetti, T., Marban, E. & Vassalli, G. Roles of exosomes in cardioprotection. Eur. Heart J. http://dx.doi.org/10.1093/eurheartj/ehw304 (2016).
-
(2016)
Eur. Heart J.
-
-
Barile, L.1
Moccetti, T.2
Marban, E.3
Vassalli, G.4
-
76
-
-
84899980641
-
Exosomes as critical agents of cardiac regeneration triggered by cell therapy
-
Ibrahim, A. G., Cheng, K. & Marban, E. Exosomes as critical agents of cardiac regeneration triggered by cell therapy. Stem Cell Rep. 2, 606-619 (2014).
-
(2014)
Stem Cell Rep.
, vol.2
, pp. 606-619
-
-
Ibrahim, A.G.1
Cheng, K.2
Marban, E.3
-
77
-
-
84894239930
-
Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles
-
Giricz, Z. et al. Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles. J. Mol. Cell. Cardiol. 68, 75-78 (2014).
-
(2014)
J. Mol. Cell. Cardiol.
, vol.68
, pp. 75-78
-
-
Giricz, Z.1
-
78
-
-
84890812342
-
Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia
-
Liu, Y. et al. Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia. Proc. Natl Acad. Sci. USA 110, 20364-20371 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 20364-20371
-
-
Liu, Y.1
-
79
-
-
84989912449
-
Decreased autophagy: A major factor for cardiomyocyte death induced by beta1-adrenoceptor autoantibodies
-
Wang, L. et al. Decreased autophagy: a major factor for cardiomyocyte death induced by beta1-adrenoceptor autoantibodies. Cell Death Dis. 6, e1862 (2015).
-
(2015)
Cell Death Dis.
, vol.6
, pp. e1862
-
-
Wang, L.1
-
80
-
-
84966344031
-
UBC9-mediated sumoylation favorably impacts cardiac function in compromised hearts
-
Gupta, M. K. et al. UBC9-mediated sumoylation favorably impacts cardiac function in compromised hearts. Circ. Res. 118, 1894-1905 (2016).
-
(2016)
Circ. Res.
, vol.118
, pp. 1894-1905
-
-
Gupta, M.K.1
-
81
-
-
84959213319
-
Drp1-dependent mitochondrial autophagy plays a protective role against pressure overload-induced mitochondrial dysfunction and heart failure
-
Shirakabe, A. et al. Drp1-dependent mitochondrial autophagy plays a protective role against pressure overload-induced mitochondrial dysfunction and heart failure. Circulation 133, 1249-1263 (2016).
-
(2016)
Circulation
, vol.133
, pp. 1249-1263
-
-
Shirakabe, A.1
-
82
-
-
84962698228
-
Autophagic vacuoles in cardiomyocytes of dilated cardiomyopathy with initially decompensated heart failure predict improved prognosis
-
Saito, T. et al. Autophagic vacuoles in cardiomyocytes of dilated cardiomyopathy with initially decompensated heart failure predict improved prognosis. Autophagy 12, 579-587 (2016).
-
(2016)
Autophagy
, vol.12
, pp. 579-587
-
-
Saito, T.1
-
83
-
-
79952071913
-
Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: Mechanisms and therapeutic opportunities
-
Schlossarek, S., Mearini, G. & Carrier, L. Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: mechanisms and therapeutic opportunities. J. Mol. Cell. Cardiol. 50, 613-620 (2011).
-
(2011)
J. Mol. Cell. Cardiol.
, vol.50
, pp. 613-620
-
-
Schlossarek, S.1
Mearini, G.2
Carrier, L.3
-
84
-
-
84937970106
-
This old heart: Cardiac aging and autophagy
-
Linton, P. J., Gurney, M., Sengstock, D., Mentzer, R. M. Jr & Gottlieb, R. A. This old heart: cardiac aging and autophagy. J. Mol. Cell. Cardiol. 83, 44-54 (2015).
-
(2015)
J. Mol. Cell. Cardiol.
, vol.83
, pp. 44-54
-
-
Linton, P.J.1
Gurney, M.2
Sengstock, D.3
Mentzer, R.M.4
Gottlieb, R.A.5
-
85
-
-
84873377605
-
Cardiomyocyte-specific deletion of endothelin receptor A rescues aging-associated cardiac hypertrophy and contractile dysfunction: Role of autophagy
-
Ceylan-Isik, A. F. et al. Cardiomyocyte-specific deletion of endothelin receptor A rescues aging-associated cardiac hypertrophy and contractile dysfunction: role of autophagy. Basic Res. Cardiol. 108, 335 (2013).
-
(2013)
Basic Res. Cardiol.
, vol.108
, pp. 335
-
-
Ceylan-Isik, A.F.1
-
86
-
-
80053432592
-
Autophagy anomalies in the diabetic myocardium
-
Mellor, K. M., Reichelt, M. E. & Delbridge, L. M. Autophagy anomalies in the diabetic myocardium. Autophagy 7, 1263-1267 (2011).
-
(2011)
Autophagy
, vol.7
, pp. 1263-1267
-
-
Mellor, K.M.1
Reichelt, M.E.2
Delbridge, L.M.3
-
87
-
-
84963529445
-
Epigenetics and obesity cardiomyopathy: From pathophysiology to prevention and management
-
Zhang, Y. & Ren, J. Epigenetics and obesity cardiomyopathy: from pathophysiology to prevention and management. Pharmacol. Ther. 161, 52-66 (2016).
-
(2016)
Pharmacol. Ther.
, vol.161
, pp. 52-66
-
-
Zhang, Y.1
Ren, J.2
-
88
-
-
74149084766
-
Cardiac overexpression of metallothionein rescues cardiac contractile dysfunction and endoplasmic reticulum stress but not autophagy in sepsis
-
Ceylan-Isik, A. F. et al. Cardiac overexpression of metallothionein rescues cardiac contractile dysfunction and endoplasmic reticulum stress but not autophagy in sepsis. J. Mol. Cell. Cardiol. 48, 367-378 (2010).
-
(2010)
J. Mol. Cell. Cardiol.
, vol.48
, pp. 367-378
-
-
Ceylan-Isik, A.F.1
-
89
-
-
61949346360
-
LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection
-
Yuan, H. et al. LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection. Am. J. Physiol. Heart Circ. Physiol. 296, H470-H479 (2009).
-
(2009)
Am. J. Physiol. Heart Circ. Physiol.
, vol.296
, pp. H470-H479
-
-
Yuan, H.1
-
90
-
-
59849110194
-
Autophagy in ischemic heart disease
-
Gustafsson, A. B. & Gottlieb, R. A. Autophagy in ischemic heart disease. Circ. Res. 104, 150-158 (2009).
-
(2009)
Circ. Res.
, vol.104
, pp. 150-158
-
-
Gustafsson, A.B.1
Gottlieb, R.A.2
-
91
-
-
34147168105
-
Distinct roles of autophagy in the heart during ischemia and reperfusion: Roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
-
Matsui, Y. et al. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ. Res. 100, 914-922 (2007).
-
(2007)
Circ. Res.
, vol.100
, pp. 914-922
-
-
Matsui, Y.1
-
92
-
-
84961223599
-
Doxorubicin blocks cardiomyocyte autophagic flux by inhibiting lysosome acidification
-
Li, D. L. et al. Doxorubicin blocks cardiomyocyte autophagic flux by inhibiting lysosome acidification. Circulation 133, 1668-1687 (2016).
-
(2016)
Circulation
, vol.133
, pp. 1668-1687
-
-
Li, D.L.1
-
93
-
-
0037453585
-
Myocytes die by multiple mechanisms in failing human hearts
-
Kostin, S. et al. Myocytes die by multiple mechanisms in failing human hearts. Circ. Res. 92, 715-724 (2003).
-
(2003)
Circ. Res.
, vol.92
, pp. 715-724
-
-
Kostin, S.1
-
94
-
-
47749125013
-
Autophagy is an adaptive response in desmin-related cardiomyopathy
-
Tannous, P. et al. Autophagy is an adaptive response in desmin-related cardiomyopathy. Proc. Natl Acad. Sci. USA 105, 9745-9750 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 9745-9750
-
-
Tannous, P.1
-
95
-
-
67049115754
-
Angiotensin II type 2 receptor antagonizes angiotensin II type 1 receptor-mediated cardiomyocyte autophagy
-
Porrello, E. R. et al. Angiotensin II type 2 receptor antagonizes angiotensin II type 1 receptor-mediated cardiomyocyte autophagy. Hypertension 53, 1032-1040 (2009).
-
(2009)
Hypertension
, vol.53
, pp. 1032-1040
-
-
Porrello, E.R.1
-
96
-
-
73449127222
-
Cardiomyocyte autophagy is regulated by angiotensin II type 1 and type 2 receptors
-
Porrello, E. R. & Delbridge, L. M. Cardiomyocyte autophagy is regulated by angiotensin II type 1 and type 2 receptors. Autophagy 5, 1215-1216 (2009).
-
(2009)
Autophagy
, vol.5
, pp. 1215-1216
-
-
Porrello, E.R.1
Delbridge, L.M.2
-
97
-
-
84983002206
-
Distinct changes of myocyte autophagy during myocardial hypertrophy and heart failure: Association with oxidative stress
-
Li, B., Chi, R. F., Qin, F. Z. & Guo, X. F. Distinct changes of myocyte autophagy during myocardial hypertrophy and heart failure: association with oxidative stress. Exp. Physiol. 101, 1050-1063 (2016).
-
(2016)
Exp. Physiol.
, vol.101
, pp. 1050-1063
-
-
Li, B.1
Chi, R.F.2
Qin, F.Z.3
Guo, X.F.4
-
98
-
-
0023608747
-
Short-term inhibition of cardiac cellular autophagy by isoproterenol
-
Pfeifer, U., Fohr, J., Wilhelm, W. & Dammrich, J. Short-term inhibition of cardiac cellular autophagy by isoproterenol. J. Mol. Cell. Cardiol. 19, 1179-1184 (1987).
-
(1987)
J. Mol. Cell. Cardiol.
, vol.19
, pp. 1179-1184
-
-
Pfeifer, U.1
Fohr, J.2
Wilhelm, W.3
Dammrich, J.4
-
99
-
-
34447133404
-
Cardiac autophagy is a maladaptive response to hemodynamic stress
-
Zhu, H. et al. Cardiac autophagy is a maladaptive response to hemodynamic stress. J. Clin. Invest. 117, 1782-1793 (2007).
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1782-1793
-
-
Zhu, H.1
-
100
-
-
27844561464
-
Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo
-
Ha, T. et al. Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo. Free Radic. Biol. Med. 39, 1570-1580 (2005).
-
(2005)
Free Radic. Biol. Med.
, vol.39
, pp. 1570-1580
-
-
Ha, T.1
-
101
-
-
34347244963
-
Rapamycin prevents thyroid hormone-induced cardiac hypertrophy
-
Kuzman, J. A., O'Connell, T. D. & Gerdes, A. M. Rapamycin prevents thyroid hormone-induced cardiac hypertrophy. Endocrinology 148, 3477-3484 (2007).
-
(2007)
Endocrinology
, vol.148
, pp. 3477-3484
-
-
Kuzman, J.A.1
O'Connell, T.D.2
Gerdes, A.M.3
-
102
-
-
84968719073
-
And autophagy in the heart
-
Shirakabe, A., Ikeda, Y., Sciarretta, S., Zablocki, D. K. & Sadoshima, J. Aging and autophagy in the heart. Circ. Res. 118, 1563-1576 (2016).
-
(2016)
Circ. Res.
, vol.118
, pp. 1563-1576
-
-
Shirakabe, A.1
Ikeda, Y.2
Sciarretta, S.3
Zablocki, D.K.4
Aging, S.J.5
-
103
-
-
34548512483
-
Autophagy in the heart and liver during normal aging and calorie restriction
-
Wohlgemuth, S. E. et al. Autophagy in the heart and liver during normal aging and calorie restriction. Rejuvenation Res. 10, 281-292 (2007).
-
(2007)
Rejuvenation Res.
, vol.10
, pp. 281-292
-
-
Wohlgemuth, S.E.1
-
104
-
-
77955342581
-
Inhibition of autophagy in the heart induces age-related cardiomyopathy
-
Taneike, M. et al. Inhibition of autophagy in the heart induces age-related cardiomyopathy. Autophagy 6, 600-606 (2010).
-
(2010)
Autophagy
, vol.6
, pp. 600-606
-
-
Taneike, M.1
-
105
-
-
84891370240
-
Essential role for UVRAG in autophagy and maintenance of cardiac function
-
Song, Z. et al. Essential role for UVRAG in autophagy and maintenance of cardiac function. Cardiovasc. Res. 101, 48-56 (2014).
-
(2014)
Cardiovasc. Res.
, vol.101
, pp. 48-56
-
-
Song, Z.1
-
106
-
-
84856746125
-
Chronic Akt activation accentuates aging-induced cardiac hypertrophy and myocardial contractile dysfunction: Role of autophagy
-
Hua, Y. et al. Chronic Akt activation accentuates aging-induced cardiac hypertrophy and myocardial contractile dysfunction: role of autophagy. Basic Res. Cardiol. 106, 1173-1191 (2011).
-
(2011)
Basic Res. Cardiol.
, vol.106
, pp. 1173-1191
-
-
Hua, Y.1
-
107
-
-
85019864128
-
Restoring pharmacologic preconditioning in the aging heart: Role of mitophagy/autophagy
-
Ma, L. et al. Restoring pharmacologic preconditioning in the aging heart: role of mitophagy/autophagy. J. Gerontol. A Biol. Sci. Med. Sci. http://dx.doi.org/ 10.1093/gerona/glw168 (2016).
-
(2016)
J. Gerontol. A Biol. Sci. Med. Sci.
-
-
Ma, L.1
-
108
-
-
79956330068
-
Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy
-
Boyle, A. J. et al. Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy. Exp. Gerontol. 46, 549-559 (2011).
-
(2011)
Exp. Gerontol.
, vol.46
, pp. 549-559
-
-
Boyle, A.J.1
-
109
-
-
70350540920
-
Suppression of phosphoinositide 3-kinase prevents cardiac aging in mice
-
Inuzuka, Y. et al. Suppression of phosphoinositide 3-kinase prevents cardiac aging in mice. Circulation 120, 1695-1703 (2009).
-
(2009)
Circulation
, vol.120
, pp. 1695-1703
-
-
Inuzuka, Y.1
-
110
-
-
84966711823
-
Aging is associated with hypermethylation of autophagy genes in macrophages
-
Khalil, H. et al. Aging is associated with hypermethylation of autophagy genes in macrophages. Epigenetics 11, 381-388 (2016).
-
(2016)
Epigenetics
, vol.11
, pp. 381-388
-
-
Khalil, H.1
-
111
-
-
78149279712
-
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
-
Russell, R. R. III et al. AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury. J. Clin. Invest. 114, 495-503 (2004).
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 495-503
-
-
Russell, R.R.1
-
112
-
-
84951274163
-
The AMPK agonist PT1 and mTOR inhibitor 3HOI-BA-01 protect cardiomyocytes after ischemia through induction of autophagy
-
Huang, L. et al. The AMPK agonist PT1 and mTOR inhibitor 3HOI-BA-01 protect cardiomyocytes after ischemia through induction of autophagy. J. Cardiovasc. Pharmacol. Ther. 21, 70-81 (2016).
-
(2016)
J. Cardiovasc. Pharmacol. Ther.
, vol.21
, pp. 70-81
-
-
Huang, L.1
-
113
-
-
77955518491
-
Autophagy induced by ischemic preconditioning is essential for cardioprotection
-
Huang, C. et al. Autophagy induced by ischemic preconditioning is essential for cardioprotection. J. Cardiovasc. Transl. Res. 3, 365-373 (2010).
-
(2010)
J. Cardiovasc. Transl. Res.
, vol.3
, pp. 365-373
-
-
Huang, C.1
-
114
-
-
84877626889
-
Activation of autophagy in ischemic postconditioning contributes to cardioprotective effects against ischemia/ reperfusion injury in rat hearts
-
Wei, C., Li, H., Han, L., Zhang, L. & Yang, X. Activation of autophagy in ischemic postconditioning contributes to cardioprotective effects against ischemia/ reperfusion injury in rat hearts. J. Cardiovasc. Pharmacol. 61, 416-422 (2013).
-
(2013)
J. Cardiovasc. Pharmacol.
, vol.61
, pp. 416-422
-
-
Wei, C.1
Li, H.2
Han, L.3
Zhang, L.4
Yang, X.5
-
115
-
-
62249157748
-
Autophagy is required for preconditioning by the adenosine A1 receptor-selective agonist CCPA
-
Yitzhaki, S. et al. Autophagy is required for preconditioning by the adenosine A1 receptor-selective agonist CCPA. Basic Res. Cardiol. 104, 157-167 (2009).
-
(2009)
Basic Res. Cardiol.
, vol.104
, pp. 157-167
-
-
Yitzhaki, S.1
-
116
-
-
84914669992
-
The cardioprotection of the insulin-mediated PI3K/Akt/mTOR signaling pathway
-
Yao, H., Han, X. & Han, X. The cardioprotection of the insulin-mediated PI3K/Akt/mTOR signaling pathway. Am. J. Cardiovasc. Drugs 14, 433-442 (2014).
-
(2014)
Am. J. Cardiovasc. Drugs
, vol.14
, pp. 433-442
-
-
Yao, H.1
Han, X.2
Han, X.3
-
117
-
-
84920815706
-
The GSK-3 family as therapeutic target for myocardial diseases
-
Lal, H., Ahmad, F., Woodgett, J. & Force, T. The GSK-3 family as therapeutic target for myocardial diseases. Circ. Res. 116, 138-149 (2015).
-
(2015)
Circ. Res.
, vol.116
, pp. 138-149
-
-
Lal, H.1
Ahmad, F.2
Woodgett, J.3
Force, T.4
-
118
-
-
84856423549
-
Glycogen synthase kinase-3β controls autophagy during myocardial ischemia and reperfusion
-
Zhai, P. & Sadoshima, J. Glycogen synthase kinase-3β controls autophagy during myocardial ischemia and reperfusion. Autophagy 8, 138-139 (2012).
-
(2012)
Autophagy
, vol.8
, pp. 138-139
-
-
Zhai, P.1
Sadoshima, J.2
-
119
-
-
79956126271
-
Oxidative stress stimulates autophagic flux during ischemia/ reperfusion
-
Hariharan, N., Zhai, P. & Sadoshima, J. Oxidative stress stimulates autophagic flux during ischemia/ reperfusion. Antioxid. Redox Signal. 14, 2179-2190 (2011).
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 2179-2190
-
-
Hariharan, N.1
Zhai, P.2
Sadoshima, J.3
-
120
-
-
33749570745
-
Enhancing macroautophagy protects against ischemia/ reperfusion injury in cardiac myocytes
-
Hamacher-Brady, A., Brady, N. R. & Gottlieb, R. A. Enhancing macroautophagy protects against ischemia/ reperfusion injury in cardiac myocytes. J. Biol. Chem. 281, 29776-29787 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 29776-29787
-
-
Hamacher-Brady, A.1
Brady, N.R.2
Gottlieb, R.A.3
-
121
-
-
84863192578
-
Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/ reperfusion injury
-
Ma, X. et al. Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/ reperfusion injury. Circulation 125, 3170-3181 (2012).
-
(2012)
Circulation
, vol.125
, pp. 3170-3181
-
-
Ma, X.1
-
122
-
-
84990895441
-
Autophagy protects cardiomyocytes from the myocardial ischaemia-reperfusion injury through the clearance of CLP36
-
Li, S. et al. Autophagy protects cardiomyocytes from the myocardial ischaemia-reperfusion injury through the clearance of CLP36. Open Biol. 6, 160177 (2016).
-
(2016)
Open Biol.
, vol.6
, pp. 160177
-
-
Li, S.1
-
123
-
-
84963721844
-
Post-translational modulation of FoxO1 contributes to cardiac remodeling in post-ischemic heart failure
-
Kappel, B. A. et al. Post-translational modulation of FoxO1 contributes to cardiac remodeling in post-ischemic heart failure. Atherosclerosis 249, 148-156 (2016).
-
(2016)
Atherosclerosis
, vol.249
, pp. 148-156
-
-
Kappel, B.A.1
-
124
-
-
84923147814
-
Regulation of the transcription factor EB-PGC1α axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stress
-
Ma, X. et al. Regulation of the transcription factor EB-PGC1α axis by beclin-1 controls mitochondrial quality and cardiomyocyte death under stress. Mol. Cell. Biol. 35, 956-976 (2015).
-
(2015)
Mol. Cell. Biol.
, vol.35
, pp. 956-976
-
-
Ma, X.1
-
125
-
-
79955658311
-
Myocardial autophagy activation and suppressed survival signaling is associated with insulin resistance in fructose-fed mice
-
Mellor, K. M., Bell, J. R., Young, M. J., Ritchie, R. H. & Delbridge, L. M. Myocardial autophagy activation and suppressed survival signaling is associated with insulin resistance in fructose-fed mice. J. Mol. Cell. Cardiol. 50, 1035-1043 (2011).
-
(2011)
J. Mol. Cell. Cardiol.
, vol.50
, pp. 1035-1043
-
-
Mellor, K.M.1
Bell, J.R.2
Young, M.J.3
Ritchie, R.H.4
Delbridge, L.M.5
-
126
-
-
79959385996
-
Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice
-
Xie, Z. et al. Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice. Diabetes 60, 1770-1778 (2011).
-
(2011)
Diabetes
, vol.60
, pp. 1770-1778
-
-
Xie, Z.1
-
127
-
-
84942252892
-
Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway
-
Munasinghe, P. E. et al. Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway. Int. J. Cardiol. 202, 13-20 (2016).
-
(2016)
Int. J. Cardiol.
, vol.202
, pp. 13-20
-
-
Munasinghe, P.E.1
-
128
-
-
84912558699
-
Resveratrol-enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice
-
Wang, B. et al. Resveratrol-enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice. J. Cell. Mol. Med. 18, 1599-1611 (2014).
-
(2014)
J. Cell. Mol. Med.
, vol.18
, pp. 1599-1611
-
-
Wang, B.1
-
129
-
-
84988661115
-
Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes
-
Trivedi, P. C. et al. Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes. Biochim. Biophys. Acta 1861, 1893-1910 (2016).
-
(2016)
Biochim. Biophys. Acta
, vol.1861
, pp. 1893-1910
-
-
Trivedi, P.C.1
-
130
-
-
84880065357
-
Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes
-
Xu, X. et al. Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes. J. Biol. Chem. 288, 18077-18092 (2013).
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 18077-18092
-
-
Xu, X.1
-
131
-
-
84983747543
-
Discordant signaling and autophagy response to fasting in hearts of obese mice: Implications for ischemia tolerance
-
Andres, A. M. et al. Discordant signaling and autophagy response to fasting in hearts of obese mice: implications for ischemia tolerance. Am. J. Physiol. Heart Circ. Physiol. 311, H219-H228 (2016).
-
(2016)
Am. J. Physiol. Heart Circ. Physiol.
, vol.311
, pp. H219-H228
-
-
Andres, A.M.1
-
132
-
-
84874315293
-
Akt2 knockout preserves cardiac function in high-fat diet-induced obesity by rescuing cardiac autophagosome maturation
-
Xu, X., Hua, Y., Nair, S., Zhang, Y. & Ren, J. Akt2 knockout preserves cardiac function in high-fat diet-induced obesity by rescuing cardiac autophagosome maturation. J. Mol. Cell. Biol. 5, 61-63 (2013).
-
(2013)
J. Mol. Cell. Biol.
, vol.5
, pp. 61-63
-
-
Xu, X.1
Hua, Y.2
Nair, S.3
Zhang, Y.4
Ren, J.5
-
133
-
-
84924618437
-
Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity
-
Jaishy, B. et al. Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity. J. Lipid Res. 56, 546-561 (2015).
-
(2015)
J. Lipid Res.
, vol.56
, pp. 546-561
-
-
Jaishy, B.1
-
134
-
-
84906070274
-
Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients
-
Montaigne, D. et al. Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients. Circulation 130, 554-564 (2014).
-
(2014)
Circulation
, vol.130
, pp. 554-564
-
-
Montaigne, D.1
-
135
-
-
84973520065
-
Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice
-
Zhang, J. et al. Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice. Clin. Sci. (Lond.) 130, 625-641 (2016).
-
(2016)
Clin. Sci. (Lond.)
, vol.130
, pp. 625-641
-
-
Zhang, J.1
-
136
-
-
84875450015
-
Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes
-
He, C., Zhu, H., Li, H., Zou, M. H. & Xie, Z. Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes. Diabetes 62, 1270-1281 (2013).
-
(2013)
Diabetes
, vol.62
, pp. 1270-1281
-
-
He, C.1
Zhu, H.2
Li, H.3
Zou, M.H.4
Xie, Z.5
-
137
-
-
84924297804
-
Protective effects of desacyl ghrelin on diabetic cardiomyopathy
-
Pei, X. M. et al. Protective effects of desacyl ghrelin on diabetic cardiomyopathy. Acta Diabetol. 52, 293-306 (2015).
-
(2015)
Acta Diabetol.
, vol.52
, pp. 293-306
-
-
Pei, X.M.1
-
138
-
-
84943740308
-
Autophagic adaptations in diabetic cardiomyopathy differ between type 1 and type 2 diabetes
-
Kanamori, H. et al. Autophagic adaptations in diabetic cardiomyopathy differ between type 1 and type 2 diabetes. Autophagy 11, 1146-1160 (2015).
-
(2015)
Autophagy
, vol.11
, pp. 1146-1160
-
-
Kanamori, H.1
-
139
-
-
84903952217
-
(-)-epigallocatechin-3-gallate attenuated myocardial mitochondrial dysfunction and autophagy in diabetic Goto-Kakizaki rats
-
Liu, J. et al. (-)-epigallocatechin-3-gallate attenuated myocardial mitochondrial dysfunction and autophagy in diabetic Goto-Kakizaki rats. Free Radic. Res. 48, 898-906 (2014).
-
(2014)
Free Radic. Res.
, vol.48
, pp. 898-906
-
-
Liu, J.1
-
140
-
-
84985903406
-
Chloroquine improves left ventricle diastolic function in streptozotocin-induced diabetic mice
-
Yuan, X. et al. Chloroquine improves left ventricle diastolic function in streptozotocin-induced diabetic mice. Drug Des. Devel. Ther. 10, 2729-2737 (2016).
-
(2016)
Drug Des. Devel. Ther.
, vol.10
, pp. 2729-2737
-
-
Yuan, X.1
-
141
-
-
84920407208
-
Development of autophagy inducers in clinical medicine
-
Levine, B., Packer, M. & Codogno, P. Development of autophagy inducers in clinical medicine. J. Clin. Invest. 125, 14-24 (2015).
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 14-24
-
-
Levine, B.1
Packer, M.2
Codogno, P.3
-
142
-
-
84890072367
-
Enhanced autophagy ameliorates cardiac proteinopathy
-
Bhuiyan, M. S. et al. Enhanced autophagy ameliorates cardiac proteinopathy. J. Clin. Invest. 123, 5284-5297 (2013).
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 5284-5297
-
-
Bhuiyan, M.S.1
-
143
-
-
84880236360
-
Fluorescence tomography of rapamycin-induced autophagy and cardioprotection in vivo
-
Chen, H. H. et al. Fluorescence tomography of rapamycin-induced autophagy and cardioprotection in vivo. Circ. Cardiovasc. Imaging 6, 441-447 (2013).
-
(2013)
Circ. Cardiovasc. Imaging
, vol.6
, pp. 441-447
-
-
Chen, H.H.1
-
144
-
-
77949357437
-
Cardioprotection by resveratrol: A novel mechanism via autophagy involving the mTORC2 pathway
-
Gurusamy, N. et al. Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway. Cardiovasc. Res. 86, 103-112 (2010).
-
(2010)
Cardiovasc. Res.
, vol.86
, pp. 103-112
-
-
Gurusamy, N.1
-
145
-
-
84922515068
-
Rapamycin protects cardiomyocytes against anoxia/reoxygenation injury by inducing autophagy through the PI3k/Akt pathway
-
Wang, L. Q., Cheng, X. S., Huang, C. H., Huang, B. & Liang, Q. Rapamycin protects cardiomyocytes against anoxia/reoxygenation injury by inducing autophagy through the PI3k/Akt pathway. J. Huazhong Univ. Sci. Technolog. Med. Sci. 35, 10-15 (2015).
-
(2015)
J. Huazhong Univ. Sci. Technolog. Med. Sci.
, vol.35
, pp. 10-15
-
-
Wang, L.Q.1
Cheng, X.S.2
Huang, C.H.3
Huang, B.4
Liang, Q.5
-
146
-
-
84902579141
-
Nicotinamide mononucleotide, an intermediate of NAD+ synthesis, protects the heart from ischemia and reperfusion
-
Yamamoto, T. et al. Nicotinamide mononucleotide, an intermediate of NAD+ synthesis, protects the heart from ischemia and reperfusion. PLoS ONE 9, e98972 (2014).
-
(2014)
PLoS ONE
, vol.9
, pp. e98972
-
-
Yamamoto, T.1
-
147
-
-
84924057912
-
Hydrogen sulfide protects against myocardial ischemia and reperfusion injury by activating AMP-activated protein kinase to restore autophagic flux
-
Xie, H. et al. Hydrogen sulfide protects against myocardial ischemia and reperfusion injury by activating AMP-activated protein kinase to restore autophagic flux. Biochem. Biophys. Res. Commun. 458, 632-638 (2015).
-
(2015)
Biochem. Biophys. Res. Commun.
, vol.458
, pp. 632-638
-
-
Xie, H.1
-
148
-
-
84895923936
-
Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy
-
Xie, M. et al. Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy. Circulation 129, 1139-1151 (2014).
-
(2014)
Circulation
, vol.129
, pp. 1139-1151
-
-
Xie, M.1
-
149
-
-
84963612261
-
Inhibition of class i histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression
-
Morales, C. R. et al. Inhibition of class I histone deacetylases blunts cardiac hypertrophy through TSC2-dependent mTOR repression. Sci. Signal. 9, ra34 (2016).
-
(2016)
Sci. Signal.
, vol.9
, pp. ra34
-
-
Morales, C.R.1
-
150
-
-
58149396003
-
Autophagy in load-induced heart disease
-
Rothermel, B. A. & Hill, J. A. Autophagy in load-induced heart disease. Circ. Res. 103, 1363-1369 (2008).
-
(2008)
Circ. Res.
, vol.103
, pp. 1363-1369
-
-
Rothermel, B.A.1
Hill, J.A.2
-
151
-
-
45149116776
-
Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury
-
Yasuda, H. et al. Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury. Am. J. Physiol. Renal Physiol. 294, F1050-F1058 (2008).
-
(2008)
Am. J. Physiol. Renal Physiol.
, vol.294
, pp. F1050-F1058
-
-
Yasuda, H.1
-
152
-
-
0022552566
-
Influence of agents that alter lysosomal function on fetal mouse hearts recovering from anoxia and substrate depletion
-
Ridout, R. M., Wildenthal, K. & Decker, R. S. Influence of agents that alter lysosomal function on fetal mouse hearts recovering from anoxia and substrate depletion. J. Mol. Cell. Cardiol. 18, 867-876 (1986).
-
(1986)
J. Mol. Cell. Cardiol.
, vol.18
, pp. 867-876
-
-
Ridout, R.M.1
Wildenthal, K.2
Decker, R.S.3
-
153
-
-
84992153372
-
Preclinical development of a microRNA-based therapy for elderly patients with myocardial infarction
-
Gupta, S. K. et al. Preclinical development of a microRNA-based therapy for elderly patients with myocardial infarction. J. Am. Coll. Cardiol. 68, 1557-1571 (2016).
-
(2016)
J. Am. Coll. Cardiol.
, vol.68
, pp. 1557-1571
-
-
Gupta, S.K.1
-
154
-
-
84863839690
-
Verapamil stereoisomers induce antiproliferative effects in vascular smooth muscle cells via autophagy
-
Salabei, J. K. et al. Verapamil stereoisomers induce antiproliferative effects in vascular smooth muscle cells via autophagy. Toxicol. Appl. Pharmacol. 262, 265-272 (2012).
-
(2012)
Toxicol. Appl. Pharmacol.
, vol.262
, pp. 265-272
-
-
Salabei, J.K.1
-
155
-
-
84961203595
-
Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts
-
Chiao, Y. A. et al. Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts. Aging (Albany NY) 8, 314-327 (2016).
-
(2016)
Aging (Albany NY)
, vol.8
, pp. 314-327
-
-
Chiao, Y.A.1
-
156
-
-
78650277944
-
Beta2-adrenergic receptor regulates cardiac fibroblast autophagy and collagen degradation
-
Aranguiz-Urroz, P. et al. Beta2-adrenergic receptor regulates cardiac fibroblast autophagy and collagen degradation. Biochim. Biophys. Acta 1812, 23-31 (2011).
-
(2011)
Biochim. Biophys. Acta
, vol.1812
, pp. 23-31
-
-
Aranguiz-Urroz, P.1
-
157
-
-
0023220047
-
Short-term inhibition of cellular autophagy by isoproterenol in the submandibular gland
-
Bahro, M., Dammrich, J. & Pfeifer, U. Short-term inhibition of cellular autophagy by isoproterenol in the submandibular gland. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. 53, 32-36 (1987).
-
(1987)
Virchows Arch. B Cell Pathol. Incl. Mol. Pathol.
, vol.53
, pp. 32-36
-
-
Bahro, M.1
Dammrich, J.2
Pfeifer, U.3
-
158
-
-
84951793287
-
Acute effects of statin on reduction of angiopoietin-like 2 and glyceraldehyde-derived advanced glycation end-products levels in patients with acute myocardial infarction: A message from SAMIT (Statin for Acute Myocardial Infarction Trial)
-
Shimomura, M. et al. Acute effects of statin on reduction of angiopoietin-like 2 and glyceraldehyde-derived advanced glycation end-products levels in patients with acute myocardial infarction: a message from SAMIT (Statin for Acute Myocardial Infarction Trial). Heart Vessels 31, 1583-1589 (2016).
-
(2016)
Heart Vessels
, vol.31
, pp. 1583-1589
-
-
Shimomura, M.1
-
159
-
-
84867900547
-
Early statin treatment prior to primary PCI for acute myocardial infarction: REPERATOR, a randomized placebo-controlled pilot trial
-
Post, S. et al. Early statin treatment prior to primary PCI for acute myocardial infarction: REPERATOR, a randomized placebo-controlled pilot trial. Catheter Cardiovasc. Interv. 80, 756-765 (2012).
-
(2012)
Catheter Cardiovasc. Interv.
, vol.80
, pp. 756-765
-
-
Post, S.1
-
160
-
-
84956630703
-
Thirty years of BCL-2: Translating cell death discoveries into novel cancer therapies
-
Delbridge, A. R., Grabow, S., Strasser, A. & Vaux, D. L. Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies. Nat. Rev. Cancer 16, 99-109 (2016).
-
(2016)
Nat. Rev. Cancer
, vol.16
, pp. 99-109
-
-
Delbridge, A.R.1
Grabow, S.2
Strasser, A.3
Vaux, D.L.4
-
161
-
-
84870662316
-
Autophagy contributes to retardation of cardiac growth in diabetic rats
-
Lee, Y., Hong, Y., Lee, S. R., Chang, K. T. & Hong, Y. Autophagy contributes to retardation of cardiac growth in diabetic rats. Lab. Anim. Res. 28, 99-107 (2012).
-
(2012)
Lab. Anim. Res.
, vol.28
, pp. 99-107
-
-
Lee, Y.1
Hong, Y.2
Lee, S.R.3
Chang, K.T.4
Hong, Y.5
-
162
-
-
84863044821
-
Ischemia-reperfusion injury leads to distinct temporal cardiac remodeling in normal versus diabetic mice
-
Eguchi, M. et al. Ischemia-reperfusion injury leads to distinct temporal cardiac remodeling in normal versus diabetic mice. PLoS ONE 7, e30450 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e30450
-
-
Eguchi, M.1
-
163
-
-
84950276708
-
Lin28a protects against diabetic cardiomyopathy via the PKA/ROCK2 pathway
-
Sun, S. et al. Lin28a protects against diabetic cardiomyopathy via the PKA/ROCK2 pathway. Biochem. Biophys. Res. Commun. 469, 29-36 (2016).
-
(2016)
Biochem. Biophys. Res. Commun.
, vol.469
, pp. 29-36
-
-
Sun, S.1
-
164
-
-
84884562299
-
Heme oxygenase-1 prevents cardiac dysfunction in streptozotocin-diabetic mice by reducing inflammation, oxidative stress, apoptosis and enhancing autophagy
-
Zhao, Y. et al. Heme oxygenase-1 prevents cardiac dysfunction in streptozotocin-diabetic mice by reducing inflammation, oxidative stress, apoptosis and enhancing autophagy. PLoS ONE 8, e75927 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e75927
-
-
Zhao, Y.1
-
165
-
-
84981232786
-
MST1 coordinately regulates autophagy and apoptosis in diabetic cardiomyopathy in mice
-
Zhang, M. et al. MST1 coordinately regulates autophagy and apoptosis in diabetic cardiomyopathy in mice. Diabetologia 59, 2435-2447 (2016).
-
(2016)
Diabetologia
, vol.59
, pp. 2435-2447
-
-
Zhang, M.1
-
166
-
-
84906848581
-
Diet control to achieve euglycemia induces significant loss of heart and liver weight via increased autophagy compared with ad libitum diet in diabetic rats
-
Lee, J. H. et al. Diet control to achieve euglycemia induces significant loss of heart and liver weight via increased autophagy compared with ad libitum diet in diabetic rats. Exp. Mol. Med. 46, e111 (2014).
-
(2014)
Exp. Mol. Med.
, vol.46
, pp. e111
-
-
Lee, J.H.1
-
167
-
-
84875210462
-
Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart
-
Marsh, S. A., Powell, P. C., Dell'italia, L. J. & Chatham, J. C. Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart. Life Sci. 92, 648-656 (2013).
-
(2013)
Life Sci.
, vol.92
, pp. 648-656
-
-
Marsh, S.A.1
Powell, P.C.2
Dell'Italia, L.J.3
Chatham, J.C.4
-
168
-
-
84954245545
-
Sequential changes in autophagy in diabetic cardiac fibrosis
-
Gao, H., Yang, Q., Dong, R., Hou, F. & Wu, Y. Sequential changes in autophagy in diabetic cardiac fibrosis. Mol. Med. Rep. 13, 327-332 (2016).
-
(2016)
Mol. Med. Rep.
, vol.13
, pp. 327-332
-
-
Gao, H.1
Yang, Q.2
Dong, R.3
Hou, F.4
Wu, Y.5
-
169
-
-
84963576915
-
Multi-strain probiotics inhibit cardiac myopathies and autophagy to prevent heart injury in high-fat diet-fed rats
-
Lai, C. H. et al. Multi-strain probiotics inhibit cardiac myopathies and autophagy to prevent heart injury in high-fat diet-fed rats. Int. J. Med. Sci. 13, 277-285 (2016).
-
(2016)
Int. J. Med. Sci.
, vol.13
, pp. 277-285
-
-
Lai, C.H.1
-
170
-
-
84911472579
-
Adiponectin receptor 1 overexpression reduces lipid accumulation and hypertrophy in the heart of diet-induced obese mice - Possible involvement of oxidative stress and autophagy
-
Chou, I. P. et al. Adiponectin receptor 1 overexpression reduces lipid accumulation and hypertrophy in the heart of diet-induced obese mice - possible involvement of oxidative stress and autophagy. Endocr. Res. 39, 173-179 (2014).
-
(2014)
Endocr. Res.
, vol.39
, pp. 173-179
-
-
Chou, I.P.1
-
171
-
-
84868628424
-
Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes
-
Russo, S. B. et al. Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes. J. Clin. Invest. 122, 3919-3930 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3919-3930
-
-
Russo, S.B.1
-
172
-
-
84877355166
-
Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: Role of autophagy
-
Guo, R., Zhang, Y., Turdi, S. & Ren, J. Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: role of autophagy. Biochim. Biophys. Acta 1832, 1136-1148 (2013).
-
(2013)
Biochim. Biophys. Acta
, vol.1832
, pp. 1136-1148
-
-
Guo, R.1
Zhang, Y.2
Turdi, S.3
Ren, J.4
-
173
-
-
84878699998
-
Chronic caloric restriction and exercise improve metabolic conditions of dietary-induced obese mice in autophagy correlated manner without involving AMPK
-
Cui, M., Yu, H., Wang, J., Gao, J. & Li, J. Chronic caloric restriction and exercise improve metabolic conditions of dietary-induced obese mice in autophagy correlated manner without involving AMPK. J. Diabetes Res. 2013, 852754 (2013).
-
(2013)
J. Diabetes Res.
, vol.2013
, pp. 852754
-
-
Cui, M.1
Yu, H.2
Wang, J.3
Gao, J.4
Li, J.5
-
174
-
-
84863393597
-
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
-
He, C. et al. Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature 481, 511-515 (2012).
-
(2012)
Nature
, vol.481
, pp. 511-515
-
-
He, C.1
-
175
-
-
84924571278
-
Macrophage migration inhibitory factor (MIF) knockout preserves cardiac homeostasis through alleviating Akt-mediated myocardial autophagy suppression in high-fat diet-induced obesity
-
Xu, X. & Ren, J. Macrophage migration inhibitory factor (MIF) knockout preserves cardiac homeostasis through alleviating Akt-mediated myocardial autophagy suppression in high-fat diet-induced obesity. Int. J. Obes. (Lond.) 39, 387-396 (2015).
-
(2015)
Int. J. Obes. (Lond.)
, vol.39
, pp. 387-396
-
-
Xu, X.1
Ren, J.2
-
176
-
-
84939199200
-
Time-dependent cellular response in the liver and heart in a dietary-induced obese mouse model: The potential role of ER stress and autophagy
-
Hsu, H. C. et al. Time-dependent cellular response in the liver and heart in a dietary-induced obese mouse model: the potential role of ER stress and autophagy. Eur. J. Nutr. 55, 2031-2043 (2016).
-
(2016)
Eur. J. Nutr.
, vol.55
, pp. 2031-2043
-
-
Hsu, H.C.1
-
177
-
-
84864750953
-
Carbon monoxide improves cardiac function and mitochondrial population quality in a mouse model of metabolic syndrome
-
Lancel, S. et al. Carbon monoxide improves cardiac function and mitochondrial population quality in a mouse model of metabolic syndrome. PLoS ONE 7, e41836 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e41836
-
-
Lancel, S.1
|