-
1
-
-
1842583789
-
Development by self-digestion: molecular mechanisms and biological functions of autophagy
-
Levine B., Klionsky D.J. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev. Cell 2004, 6:463-477.
-
(2004)
Dev. Cell
, vol.6
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
2
-
-
34249714158
-
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
-
Nakai A., Yamaguchi O., Takeda T., Higuchi Y., Hikoso S., Taniike M., et al. The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat. Med. 2007, 13:619-624.
-
(2007)
Nat. Med.
, vol.13
, pp. 619-624
-
-
Nakai, A.1
Yamaguchi, O.2
Takeda, T.3
Higuchi, Y.4
Hikoso, S.5
Taniike, M.6
-
3
-
-
47749105267
-
Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy
-
Tannous P., Zhu H., Nemchenko A., Berry J.M., Johnstone J.L., Shelton J.M., et al. Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy. Circulation 2008, 117:3070-3078.
-
(2008)
Circulation
, vol.117
, pp. 3070-3078
-
-
Tannous, P.1
Zhu, H.2
Nemchenko, A.3
Berry, J.M.4
Johnstone, J.L.5
Shelton, J.M.6
-
4
-
-
84887495190
-
Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2
-
Maejima Y., Kyoi S., Zhai P., Liu T., Li H., Ivessa A., et al. Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nat Med. 2013, 19:1478-1488.
-
(2013)
Nat Med.
, vol.19
, pp. 1478-1488
-
-
Maejima, Y.1
Kyoi, S.2
Zhai, P.3
Liu, T.4
Li, H.5
Ivessa, A.6
-
5
-
-
84890072367
-
Enhanced autophagy ameliorates cardiac proteinopathy
-
Bhuiyan M.S., Pattison J.S., Osinska H., James J., Gulick J., McLendon P.M., et al. Enhanced autophagy ameliorates cardiac proteinopathy. J. Clin. Invest. 2013, 123:5284-5297.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 5284-5297
-
-
Bhuiyan, M.S.1
Pattison, J.S.2
Osinska, H.3
James, J.4
Gulick, J.5
McLendon, P.M.6
-
6
-
-
34147168105
-
Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
-
Matsui Y., Takagi H., Qu X., Abdellatif M., Sakoda H., Asano T., et al. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ. Res. 2007, 100:914-922.
-
(2007)
Circ. Res.
, vol.100
, pp. 914-922
-
-
Matsui, Y.1
Takagi, H.2
Qu, X.3
Abdellatif, M.4
Sakoda, H.5
Asano, T.6
-
7
-
-
34447133404
-
Cardiac autophagy is a maladaptive response to hemodynamic stress
-
Zhu H., Tannous P., Johnstone J.L., Kong Y., Shelton J.M., Richardson J.A., et al. Cardiac autophagy is a maladaptive response to hemodynamic stress. J. Clin. Invest. 2007, 117:1782-1793.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1782-1793
-
-
Zhu, H.1
Tannous, P.2
Johnstone, J.L.3
Kong, Y.4
Shelton, J.M.5
Richardson, J.A.6
-
8
-
-
79955963895
-
At the core of survival: autophagy delays the onset of both apoptotic and necrotic cell death in a model of ischemic cell injury
-
Loos B., Genade S., Ellis B., Lochner A., Engelbrecht A.M. At the core of survival: autophagy delays the onset of both apoptotic and necrotic cell death in a model of ischemic cell injury. Exp. Cell Res. 2011, 317:1437-1453.
-
(2011)
Exp. Cell Res.
, vol.317
, pp. 1437-1453
-
-
Loos, B.1
Genade, S.2
Ellis, B.3
Lochner, A.4
Engelbrecht, A.M.5
-
9
-
-
79952775153
-
Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy
-
Cao D.J., Wang Z.V., Battiprolu P.K., Jiang N., Morales C.R., Kong Y., et al. Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:4123-4128.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 4123-4128
-
-
Cao, D.J.1
Wang, Z.V.2
Battiprolu, P.K.3
Jiang, N.4
Morales, C.R.5
Kong, Y.6
-
10
-
-
84895923936
-
Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy
-
Xie M., Kong Y., Tan W., May H., Battiprolu P.K., Pedrozo Z., et al. Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy. Circulation 2014, 129:1139-1151.
-
(2014)
Circulation
, vol.129
, pp. 1139-1151
-
-
Xie, M.1
Kong, Y.2
Tan, W.3
May, H.4
Battiprolu, P.K.5
Pedrozo, Z.6
-
11
-
-
84947592469
-
Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury
-
Godar R.J., Ma X., Liu H., Murphy J.T., Weinheimer C.J., Kovacs A., et al. Repetitive stimulation of autophagy-lysosome machinery by intermittent fasting preconditions the myocardium to ischemia-reperfusion injury. Autophagy 2015, 11:1537-1560.
-
(2015)
Autophagy
, vol.11
, pp. 1537-1560
-
-
Godar, R.J.1
Ma, X.2
Liu, H.3
Murphy, J.T.4
Weinheimer, C.J.5
Kovacs, A.6
-
12
-
-
84890812342
-
Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia
-
Liu Y., Shoji-Kawata S., Sumpter R.M., Wei Y., Ginet V., Zhang L., et al. Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:20364-20371.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 20364-20371
-
-
Liu, Y.1
Shoji-Kawata, S.2
Sumpter, R.M.3
Wei, Y.4
Ginet, V.5
Zhang, L.6
-
13
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre S., Tassa A., Qu X., Garuti R., Liang X.H., Mizushima N., et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005, 122:927-939.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Liang, X.H.5
Mizushima, N.6
-
14
-
-
81055144784
-
Autophagy: renovation of cells and tissues
-
Mizushima N., Komatsu M. Autophagy: renovation of cells and tissues. Cell 2011, 147:728-741.
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
15
-
-
0035809160
-
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
-
Kihara A., Noda T., Ishihara N., Ohsumi Y. Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J. Cell Biol. 2001, 152:519-530.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 519-530
-
-
Kihara, A.1
Noda, T.2
Ishihara, N.3
Ohsumi, Y.4
-
16
-
-
59249089394
-
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG
-
Itakura E., Kishi C., Inoue K., Mizushima N. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol. Biol. Cell 2008, 19:5360-5372.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 5360-5372
-
-
Itakura, E.1
Kishi, C.2
Inoue, K.3
Mizushima, N.4
-
17
-
-
84940467196
-
Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology
-
Levine B., Liu R., Dong X., Zhong Q. Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology. Trends Cell Biol. 2015.
-
(2015)
Trends Cell Biol.
-
-
Levine, B.1
Liu, R.2
Dong, X.3
Zhong, Q.4
-
18
-
-
77953543377
-
The Beclin 1-VPS34 complex - at the crossroads of autophagy and beyond
-
Funderburk S.F., Wang Q.J., Yue Z. The Beclin 1-VPS34 complex - at the crossroads of autophagy and beyond. Trends Cell Biol. 2010, 20:355-362.
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 355-362
-
-
Funderburk, S.F.1
Wang, Q.J.2
Yue, Z.3
-
19
-
-
64049086758
-
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
-
Matsunaga K., Saitoh T., Tabata K., Omori H., Satoh T., Kurotori N., et al. Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat. Cell Biol. 2009, 11:385-396.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 385-396
-
-
Matsunaga, K.1
Saitoh, T.2
Tabata, K.3
Omori, H.4
Satoh, T.5
Kurotori, N.6
-
20
-
-
72649105081
-
Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes
-
Gannage M., Dormann D., Albrecht R., Dengjel J., Torossi T., Ramer P.C., et al. Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes. Cell Host Microbe 2009, 6:367-380.
-
(2009)
Cell Host Microbe
, vol.6
, pp. 367-380
-
-
Gannage, M.1
Dormann, D.2
Albrecht, R.3
Dengjel, J.4
Torossi, T.5
Ramer, P.C.6
-
21
-
-
67649585835
-
Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
-
Kyei G.B., Dinkins C., Davis A.S., Roberts E., Singh S.B., Dong C., et al. Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. J. Cell Biol. 2009, 186:255-268.
-
(2009)
J. Cell Biol.
, vol.186
, pp. 255-268
-
-
Kyei, G.B.1
Dinkins, C.2
Davis, A.S.3
Roberts, E.4
Singh, S.B.5
Dong, C.6
-
22
-
-
25444473426
-
Autophagy in chronically ischemic myocardium
-
Yan L., Vatner D.E., Kim S.J., Ge H., Masurekar M., Massover W.H., et al. Autophagy in chronically ischemic myocardium. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:13807-13812.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 13807-13812
-
-
Yan, L.1
Vatner, D.E.2
Kim, S.J.3
Ge, H.4
Masurekar, M.5
Massover, W.H.6
-
23
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
Zhang H., Bosch-Marce M., Shimoda L.A., Tan Y.S., Baek J.H., Wesley J.B., et al. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J. Biol. Chem. 2008, 283:10892-10903.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
Wesley, J.B.6
-
24
-
-
84919800620
-
The role of the autophagy in myocardial ischemia/reperfusion injury
-
Ma S., Wang Y., Chen Y., Cao F. The role of the autophagy in myocardial ischemia/reperfusion injury. Biochim. Biophys. Acta 1852, 2015:271-276.
-
(1852)
Biochim. Biophys. Acta
, vol.2015
, pp. 271-276
-
-
Ma, S.1
Wang, Y.2
Chen, Y.3
Cao, F.4
-
25
-
-
33744536558
-
Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury
-
Valentim L., Laurence K.M., Townsend P.A., Carroll C.J., Soond S., Scarabelli T.M., et al. Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury. J. Mol. Cell. Cardiol. 2006, 40:846-852.
-
(2006)
J. Mol. Cell. Cardiol.
, vol.40
, pp. 846-852
-
-
Valentim, L.1
Laurence, K.M.2
Townsend, P.A.3
Carroll, C.J.4
Soond, S.5
Scarabelli, T.M.6
-
26
-
-
79956126271
-
Oxidative stress stimulates autophagic flux during ischemia/reperfusion
-
Hariharan N., Zhai P., Sadoshima J. Oxidative stress stimulates autophagic flux during ischemia/reperfusion. Antioxid. Redox Signal. 2011, 14:2179-2190.
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 2179-2190
-
-
Hariharan, N.1
Zhai, P.2
Sadoshima, J.3
-
27
-
-
84863192578
-
Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia-reperfusion injury
-
Ma X., Liu H., Foyil S.R., Godar R.J., Weinheimer C.J., Hill J.A., et al. Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia-reperfusion injury. Circulation 2012.
-
(2012)
Circulation
-
-
Ma, X.1
Liu, H.2
Foyil, S.R.3
Godar, R.J.4
Weinheimer, C.J.5
Hill, J.A.6
-
28
-
-
84918825178
-
Acute consumption of a high-fat diet prior to ischemia-reperfusion results in cardioprotection through NF-kappaB-dependent regulation of autophagic pathways
-
Haar L., Ren X., Liu Y., Koch S.E., Goines J., Tranter M., et al. Acute consumption of a high-fat diet prior to ischemia-reperfusion results in cardioprotection through NF-kappaB-dependent regulation of autophagic pathways. Am. J. Physiol. Heart Circ. Physiol. 2014, 307:H1705-H1713.
-
(2014)
Am. J. Physiol. Heart Circ. Physiol.
, vol.307
, pp. H1705-H1713
-
-
Haar, L.1
Ren, X.2
Liu, Y.3
Koch, S.E.4
Goines, J.5
Tranter, M.6
-
29
-
-
84879604162
-
NF-kappaB-mediated induction of autophagy in cardiac ischemia/reperfusion injury
-
Zeng M., Wei X., Wu Z., Li W., Li B., Zhen Y., et al. NF-kappaB-mediated induction of autophagy in cardiac ischemia/reperfusion injury. Biochem. Biophys. Res. Commun. 2013, 436:180-185.
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.436
, pp. 180-185
-
-
Zeng, M.1
Wei, X.2
Wu, Z.3
Li, W.4
Li, B.5
Zhen, Y.6
-
30
-
-
84930688637
-
Beclin 1 biology and its role in heart disease
-
Zhu H., He L. Beclin 1 biology and its role in heart disease. Curr. Cardiol. Rev. 2015, 11:229-237.
-
(2015)
Curr. Cardiol. Rev.
, vol.11
, pp. 229-237
-
-
Zhu, H.1
He, L.2
-
31
-
-
84877090221
-
MiR-30a downregulation aggravates pressure overload-induced cardiomyocyte hypertrophy
-
Yin X., Peng C., Ning W., Li C., Ren Z., Zhang J., et al. miR-30a downregulation aggravates pressure overload-induced cardiomyocyte hypertrophy. Mol. Cell. Biochem. 2013, 379:1-6.
-
(2013)
Mol. Cell. Biochem.
, vol.379
, pp. 1-6
-
-
Yin, X.1
Peng, C.2
Ning, W.3
Li, C.4
Ren, Z.5
Zhang, J.6
-
32
-
-
84872240012
-
MiR-30-regulated autophagy mediates angiotensin II-induced myocardial hypertrophy
-
Pan W., Zhong Y., Cheng C., Liu B., Wang L., Li A., et al. MiR-30-regulated autophagy mediates angiotensin II-induced myocardial hypertrophy. PLoS ONE 2013, 8.
-
(2013)
PLoS ONE
, vol.8
-
-
Pan, W.1
Zhong, Y.2
Cheng, C.3
Liu, B.4
Wang, L.5
Li, A.6
-
33
-
-
84897423410
-
Activating transcription factor 3 protects against pressure-overload heart failure via the autophagy molecule Beclin-1 pathway
-
Lin H., Li H.F., Chen H.H., Lai P.F., Juan S.H., Chen J.J., et al. Activating transcription factor 3 protects against pressure-overload heart failure via the autophagy molecule Beclin-1 pathway. Mol. Pharmacol. 2014, 85:682-691.
-
(2014)
Mol. Pharmacol.
, vol.85
, pp. 682-691
-
-
Lin, H.1
Li, H.F.2
Chen, H.H.3
Lai, P.F.4
Juan, S.H.5
Chen, J.J.6
-
34
-
-
0001488499
-
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein
-
Liang X.H., Kleeman L.K., Jiang H.H., Gordon G., Goldman J.E., Berry G., et al. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J. Virol. 1998, 72:8586-8596.
-
(1998)
J. Virol.
, vol.72
, pp. 8586-8596
-
-
Liang, X.H.1
Kleeman, L.K.2
Jiang, H.H.3
Gordon, G.4
Goldman, J.E.5
Berry, G.6
-
36
-
-
84862023791
-
Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG
-
Li X., He L., Che K.H., Funderburk S.F., Pan L., Pan N., et al. Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG. Nat. Commun. 2012, 3:662.
-
(2012)
Nat. Commun.
, vol.3
, pp. 662
-
-
Li, X.1
He, L.2
Che, K.H.3
Funderburk, S.F.4
Pan, L.5
Pan, N.6
-
37
-
-
0028303384
-
A thermodynamic scale for leucine zipper stability and dimerization specificity: e and g interhelical interactions
-
Krylov D., Mikhailenko I., Vinson C. A thermodynamic scale for leucine zipper stability and dimerization specificity: e and g interhelical interactions. EMBO J. 1994, 13:2849-2861.
-
(1994)
EMBO J.
, vol.13
, pp. 2849-2861
-
-
Krylov, D.1
Mikhailenko, I.2
Vinson, C.3
-
38
-
-
0034724190
-
BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death
-
Shimizu S., Konishi A., Kodama T., Tsujimoto Y. BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:3100-3105.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 3100-3105
-
-
Shimizu, S.1
Konishi, A.2
Kodama, T.3
Tsujimoto, Y.4
-
39
-
-
70149105706
-
The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor
-
Rong Y.P., Bultynck G., Aromolaran A.S., Zhong F., Parys J.B., De Smedt H., et al. The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:14397-14402.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 14397-14402
-
-
Rong, Y.P.1
Bultynck, G.2
Aromolaran, A.S.3
Zhong, F.4
Parys, J.B.5
De Smedt, H.6
-
40
-
-
44949237240
-
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
-
Wei Y., Pattingre S., Sinha S., Bassik M., Levine B. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol. Cell 2008, 30:678-688.
-
(2008)
Mol. Cell
, vol.30
, pp. 678-688
-
-
Wei, Y.1
Pattingre, S.2
Sinha, S.3
Bassik, M.4
Levine, B.5
-
42
-
-
77956386515
-
Endogenous HMGB1 regulates autophagy
-
Tang D., Kang R., Livesey K.M., Cheh C.W., Farkas A., Loughran P., et al. Endogenous HMGB1 regulates autophagy. J. Cell Biol. 2010, 190:881-892.
-
(2010)
J. Cell Biol.
, vol.190
, pp. 881-892
-
-
Tang, D.1
Kang, R.2
Livesey, K.M.3
Cheh, C.W.4
Farkas, A.5
Loughran, P.6
-
43
-
-
77953858790
-
TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy
-
Shi C.S., Kehrl J.H. TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy. Sci. Signal. 2010, 3:ra42.
-
(2010)
Sci. Signal.
, vol.3
, pp. 42
-
-
Shi, C.S.1
Kehrl, J.H.2
-
44
-
-
34249037565
-
L-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein
-
L-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. J. Biol. Chem. 2007, 282:13123-13132.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 13123-13132
-
-
Oberstein, A.1
Jeffrey, P.D.2
Shi, Y.3
-
45
-
-
85047691556
-
Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy
-
Yamamoto S., Yang G., Zablocki D., Liu J., Hong C., Kim S.J., et al. Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy. J. Clin. Invest. 2003, 111:1463-1474.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1463-1474
-
-
Yamamoto, S.1
Yang, G.2
Zablocki, D.3
Liu, J.4
Hong, C.5
Kim, S.J.6
-
46
-
-
34248353095
-
Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction
-
Odashima M., Usui S., Takagi H., Hong C., Liu J., Yokota M., et al. Inhibition of endogenous Mst1 prevents apoptosis and cardiac dysfunction without affecting cardiac hypertrophy after myocardial infarction. Circ. Res. 2007, 100:1344-1352.
-
(2007)
Circ. Res.
, vol.100
, pp. 1344-1352
-
-
Odashima, M.1
Usui, S.2
Takagi, H.3
Hong, C.4
Liu, J.5
Yokota, M.6
-
47
-
-
77957825772
-
Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice
-
Del Re D.P., Matsuda T., Zhai P., Gao S., Clark G.J., Van Der Weyden L., et al. Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice. J. Clin. Invest. 2010, 120:3555-3567.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 3555-3567
-
-
Del Re, D.P.1
Matsuda, T.2
Zhai, P.3
Gao, S.4
Clark, G.J.5
Van Der Weyden, L.6
-
48
-
-
84863393597
-
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
-
He C., Bassik M.C., Moresi V., Sun K., Wei Y., Zou Z., et al. Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature 2012, 481:511-515.
-
(2012)
Nature
, vol.481
, pp. 511-515
-
-
He, C.1
Bassik, M.C.2
Moresi, V.3
Sun, K.4
Wei, Y.5
Zou, Z.6
-
49
-
-
85003048223
-
The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation
-
Wei Y., An Z., Zou Z., Sumpter R., Su M., Zang X., et al. The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation. Elife 2015, 4.
-
(2015)
Elife
, vol.4
-
-
Wei, Y.1
An, Z.2
Zou, Z.3
Sumpter, R.4
Su, M.5
Zang, X.6
-
50
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim J., Kundu M., Viollet B., Guan K.L. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat. Cell Biol. 2011, 13:132-141.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
51
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
Egan D.F., Shackelford D.B., Mihaylova M.M., Gelino S., Kohnz R.A., Mair W., et al. Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 2011, 331:456-461.
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
-
52
-
-
84880331368
-
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
-
Russell R.C., Tian Y., Yuan H., Park H.W., Chang Y.Y., Kim J., et al. ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. Nat. Cell Biol. 2013, 15:741-750.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 741-750
-
-
Russell, R.C.1
Tian, Y.2
Yuan, H.3
Park, H.W.4
Chang, Y.Y.5
Kim, J.6
-
53
-
-
84928031894
-
Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer
-
Song X., Kim S.Y., Zhang L., Tang D., Bartlett D.L., Kwon Y.T., et al. Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer. Cell Death Dis. 2014, 5.
-
(2014)
Cell Death Dis.
, vol.5
-
-
Song, X.1
Kim, S.Y.2
Zhang, L.3
Tang, D.4
Bartlett, D.L.5
Kwon, Y.T.6
-
54
-
-
84869147050
-
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
-
(Epub 2012 Oct 25)
-
Wang R.C., Wei Y., An Z., Zou Z., Xiao G., Bhagat G., et al. Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation. Science 2012, 338:956-959. (Epub 2012 Oct 25). 10.1126/science.1225967.
-
(2012)
Science
, vol.338
, pp. 956-959
-
-
Wang, R.C.1
Wei, Y.2
An, Z.3
Zou, Z.4
Xiao, G.5
Bhagat, G.6
-
55
-
-
84884262668
-
EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance
-
Wei Y., Zou Z., Becker N., Anderson M., Sumpter R., Xiao G., et al. EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance. Cell 2013, 154:1269-1284.
-
(2013)
Cell
, vol.154
, pp. 1269-1284
-
-
Wei, Y.1
Zou, Z.2
Becker, N.3
Anderson, M.4
Sumpter, R.5
Xiao, G.6
-
56
-
-
84898639632
-
Atomistic autophagy: the structures of cellular self-digestion
-
Hurley J.H., Schulman B.A. Atomistic autophagy: the structures of cellular self-digestion. Cell 2014, 157:300-311.
-
(2014)
Cell
, vol.157
, pp. 300-311
-
-
Hurley, J.H.1
Schulman, B.A.2
-
57
-
-
84920945138
-
A kinase-independent role for EGF receptor in autophagy initiation
-
Tan X., Thapa N., Sun Y., Anderson R.A. A kinase-independent role for EGF receptor in autophagy initiation. Cell 2015, 160:145-160.
-
(2015)
Cell
, vol.160
, pp. 145-160
-
-
Tan, X.1
Thapa, N.2
Sun, Y.3
Anderson, R.A.4
-
58
-
-
23944448372
-
Inactivation of the autophagy gene bec-1 triggers apoptotic cell death in C. elegans
-
Takacs-Vellai K., Vellai T., Puoti A., Passannante M., Wicky C., Streit A., et al. Inactivation of the autophagy gene bec-1 triggers apoptotic cell death in C. elegans. Curr. Biol. 2005, 15:1513-1517.
-
(2005)
Curr. Biol.
, vol.15
, pp. 1513-1517
-
-
Takacs-Vellai, K.1
Vellai, T.2
Puoti, A.3
Passannante, M.4
Wicky, C.5
Streit, A.6
-
59
-
-
33644599456
-
BID-deficient breast cancer MCF-7 cells as a model for the study of autophagy in cancer therapy
-
Lamparska-Przybysz M., Gajkowska B., Motyl T. BID-deficient breast cancer MCF-7 cells as a model for the study of autophagy in cancer therapy. Autophagy 2006, 2:47-48.
-
(2006)
Autophagy
, vol.2
, pp. 47-48
-
-
Lamparska-Przybysz, M.1
Gajkowska, B.2
Motyl, T.3
-
61
-
-
84864942148
-
Bim inhibits autophagy by recruiting Beclin 1 to microtubules
-
Luo S., Garcia-Arencibia M., Zhao R., Puri C., Toh P.P., Sadiq O., et al. Bim inhibits autophagy by recruiting Beclin 1 to microtubules. Mol. Cell 2012, 47:359-370.
-
(2012)
Mol. Cell
, vol.47
, pp. 359-370
-
-
Luo, S.1
Garcia-Arencibia, M.2
Zhao, R.3
Puri, C.4
Toh, P.P.5
Sadiq, O.6
-
62
-
-
57749089665
-
Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in HeLa cells
-
Cho D.H., Jo Y.K., Hwang J.J., Lee Y.M., Roh S.A., Kim J.C. Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in HeLa cells. Cancer Lett. 2009, 274:95-100.
-
(2009)
Cancer Lett.
, vol.274
, pp. 95-100
-
-
Cho, D.H.1
Jo, Y.K.2
Hwang, J.J.3
Lee, Y.M.4
Roh, S.A.5
Kim, J.C.6
-
63
-
-
77957654940
-
Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis
-
Hou W., Han J., Lu C., Goldstein L.A., Rabinowich H. Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis. Autophagy 2010, 6:891-900.
-
(2010)
Autophagy
, vol.6
, pp. 891-900
-
-
Hou, W.1
Han, J.2
Lu, C.3
Goldstein, L.A.4
Rabinowich, H.5
-
64
-
-
69649090647
-
Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis
-
Betin V.M., Lane J.D. Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis. J. Cell Sci. 2009, 122:2554-2566.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 2554-2566
-
-
Betin, V.M.1
Lane, J.D.2
-
65
-
-
77954165461
-
Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors
-
Martinez-Outschoorn U.E., Pavlides S., Whitaker-Menezes D., Daumer K.M., Milliman J.N., Chiavarina B., et al. Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors. Cell Cycle 2010, 9:2423-2433.
-
(2010)
Cell Cycle
, vol.9
, pp. 2423-2433
-
-
Martinez-Outschoorn, U.E.1
Pavlides, S.2
Whitaker-Menezes, D.3
Daumer, K.M.4
Milliman, J.N.5
Chiavarina, B.6
-
66
-
-
41149124406
-
Lithium delays progression of amyotrophic lateral sclerosis
-
Fornai F., Longone P., Cafaro L., Kastsiuchenka O., Ferrucci M., Manca M.L., et al. Lithium delays progression of amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:2052-2057.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 2052-2057
-
-
Fornai, F.1
Longone, P.2
Cafaro, L.3
Kastsiuchenka, O.4
Ferrucci, M.5
Manca, M.L.6
-
67
-
-
77954597127
-
An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis
-
Hidvegi T., Ewing M., Hale P., Dippold C., Beckett C., Kemp C., et al. An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis. Science 2010, 329:229-232.
-
(2010)
Science
, vol.329
, pp. 229-232
-
-
Hidvegi, T.1
Ewing, M.2
Hale, P.3
Dippold, C.4
Beckett, C.5
Kemp, C.6
-
68
-
-
77956396747
-
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
-
Luciani A., Villella V.R., Esposito S., Brunetti-Pierri N., Medina D., Settembre C., et al. Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition. Nat. Cell Biol. 2010, 12:863-875.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 863-875
-
-
Luciani, A.1
Villella, V.R.2
Esposito, S.3
Brunetti-Pierri, N.4
Medina, D.5
Settembre, C.6
-
69
-
-
78149319082
-
Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration
-
Grumati P., Coletto L., Sabatelli P., Cescon M., Angelin A., Bertaggia E., et al. Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration. Nat. Med. 2010, 16:1313-1320.
-
(2010)
Nat. Med.
, vol.16
, pp. 1313-1320
-
-
Grumati, P.1
Coletto, L.2
Sabatelli, P.3
Cescon, M.4
Angelin, A.5
Bertaggia, E.6
-
70
-
-
70350550208
-
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases
-
Spencer B., Potkar R., Trejo M., Rockenstein E., Patrick C., Gindi R., et al. Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases. J. Neurosci. 2009, 29:13578-13588.
-
(2009)
J. Neurosci.
, vol.29
, pp. 13578-13588
-
-
Spencer, B.1
Potkar, R.2
Trejo, M.3
Rockenstein, E.4
Patrick, C.5
Gindi, R.6
-
71
-
-
79957458183
-
Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease
-
Nascimento-Ferreira I., Santos-Ferreira T., Sousa-Ferreira L., Auregan G., Onofre I., Alves S., et al. Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease. Brain 2011, 134:1400-1415.
-
(2011)
Brain
, vol.134
, pp. 1400-1415
-
-
Nascimento-Ferreira, I.1
Santos-Ferreira, T.2
Sousa-Ferreira, L.3
Auregan, G.4
Onofre, I.5
Alves, S.6
-
72
-
-
77957221783
-
Profound cardioprotection with chloramphenicol succinate in the swine model of myocardial ischemia-reperfusion injury
-
S179-84
-
Sala-Mercado J.A., Wider J., Undyala V.V., Jahania S., Yoo W., Mentzer R.M., et al. Profound cardioprotection with chloramphenicol succinate in the swine model of myocardial ischemia-reperfusion injury. Circulation 2010, 122:S179-84.
-
(2010)
Circulation
, vol.122
-
-
Sala-Mercado, J.A.1
Wider, J.2
Undyala, V.V.3
Jahania, S.4
Yoo, W.5
Mentzer, R.M.6
-
73
-
-
34248998801
-
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1
-
Maiuri M.C., Le Toumelin G., Criollo A., Rain J.C., Gautier F., Juin P., et al. Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J. 2007, 26:2527-2539.
-
(2007)
EMBO J.
, vol.26
, pp. 2527-2539
-
-
Maiuri, M.C.1
Le Toumelin, G.2
Criollo, A.3
Rain, J.C.4
Gautier, F.5
Juin, P.6
-
74
-
-
84939866355
-
BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy
-
Pedro J.M., Wei Y., Sica V., Maiuri M.C., Zou Z., Kroemer G., et al. BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy. Autophagy 2015, 11:452-459.
-
(2015)
Autophagy
, vol.11
, pp. 452-459
-
-
Pedro, J.M.1
Wei, Y.2
Sica, V.3
Maiuri, M.C.4
Zou, Z.5
Kroemer, G.6
-
75
-
-
84873709314
-
Identification of a candidate therapeutic autophagy-inducing peptide
-
Shoji-Kawata S., Sumpter R., Leveno M., Campbell G.R., Zou Z., Kinch L., et al. Identification of a candidate therapeutic autophagy-inducing peptide. Nature 2013, 494:201-206.
-
(2013)
Nature
, vol.494
, pp. 201-206
-
-
Shoji-Kawata, S.1
Sumpter, R.2
Leveno, M.3
Campbell, G.R.4
Zou, Z.5
Kinch, L.6
-
76
-
-
84876175515
-
Drug screening for autophagy inhibitors based on the dissociation of Beclin1-Bcl2 complex using BiFC technique and mechanism of eugenol on anti-influenza A virus activity
-
Dai J.P., Zhao X.F., Zeng J., Wan Q.Y., Yang J.C., Li W.Z., et al. Drug screening for autophagy inhibitors based on the dissociation of Beclin1-Bcl2 complex using BiFC technique and mechanism of eugenol on anti-influenza A virus activity. PLoS ONE 2013, 8.
-
(2013)
PLoS ONE
, vol.8
-
-
Dai, J.P.1
Zhao, X.F.2
Zeng, J.3
Wan, Q.Y.4
Yang, J.C.5
Li, W.Z.6
|