Discordant signaling and autophagy response to fasting in hearts of obese mice: Implications for ischemia tolerance

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 311, Issue 1, 2016, Pages H219-H228

  Andres, Allen M ^a   Kooren, Joel A ^a   Parker, Sarah J ^a   Tucker, Kyle C ^a   Ravindran, Nandini ^b   Ito, Bruce R ^b   Huang, Chengqun ^a   Venkatraman, Vidya ^a   Van Eyk, Jennifer E ^a   Gottlieb, Roberta A ^a   Mentzer, Robert M ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b SAN DIEGO STATE UNIVERSITY   (United States)

Author keywords

Mammalian target of rapamycin; Metabolic syndrome; Peroxisome proliferator activated receptor ; Proteomics

Indexed keywords

ADENYLATE KINASE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN P62; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; MTOR PROTEIN, MOUSE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; SEQUESTOSOME 1; SQSTM1 PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CITRIC ACID CYCLE; CONTROLLED STUDY; DIET INDUCED OBESITY; DIET RESTRICTION; ENERGY METABOLISM; FATTY ACID OXIDATION; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HEART INFARCTION; HEART STRESS; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LIPID DIET; LIPID STORAGE; MALE; METABOLIC STRESS; METABOLIC SYNDROME X; MOUSE; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; PROTEIN PHOSPHORYLATION; PROTEIN QUALITY; PROTEOMICS; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; WEIGHT GAIN; ANIMAL; CARDIAC MUSCLE; COMPLICATION; DISEASE MODEL; GENETICS; METABOLISM; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; OBESITY; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; TIME FACTOR;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AUTOPHAGY; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; FASTING; MALE; METABOLIC SYNDROME X; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; OBESITY; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PROTEIN INTERACTION MAPS; PROTEOLYSIS; PROTEOMICS; SEQUESTOSOME-1 PROTEIN; SIGNAL TRANSDUCTION; TIME FACTORS; TOR SERINE-THREONINE KINASES;

EID: 84983747543     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00041.2016     Document Type: Article

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