Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway

International Journal of Cardiology

Volumn 202, Issue , 2016, Pages 13-20

  Munasinghe, Pujika Emani ^a   Riu, Federica ^b,c   Dixit, Parul ^a   Edamatsu, Midori ^a,d   Saxena, Pankaj ^a   Hamer, Nathan S J ^a   Galvin, Ivor F ^a   Bunton, Richard W ^a   Lequeux, Sharon ^a   Jones, Greg ^a   Lamberts, Regis R ^a   Emanueli, Costanza ^b   Madeddu, Paolo ^b   Katare, Rajesh ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^d OKAYAMA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Autophagy; Beclin 1; Diabetes; Heart disease

Indexed keywords

BECLIN 1; CASPASE 3; CASPASE 7; CELL PROTEIN; CHLOROQUINE; GLUCOSE; LC3B II PROTEIN; PROTEIN P62; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, HUMAN; BECN1 PROTEIN, MOUSE; BECN1 PROTEIN, RAT; MEMBRANE PROTEIN; RNA; SMALL INTERFERING RNA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; CELL LOSS; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DIABETIC CARDIOMYOPATHY; ELECTRON MICROSCOPY; HEART; HEART ATRIUM APPENDAGE; HEART MUSCLE CELL; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CARDIAC MUSCLE; CELL CULTURE; EXPERIMENTAL DIABETES MELLITUS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE MUTANT; PATHOLOGY; SIGNAL TRANSDUCTION; TUNEL ASSAY; ULTRASTRUCTURE; ZUCKER RAT;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BECLIN-1; BLOTTING, WESTERN; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIABETIC CARDIOMYOPATHIES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IN SITU NICK-END LABELING; MALE; MEMBRANE PROTEINS; MICE; MICE, OBESE; MICROSCOPY, ELECTRON; MYOCARDIUM; RATS; RATS, ZUCKER; RNA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84942252892     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2015.08.111     Document Type: Article

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