-
1
-
-
0037425535
-
Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic
-
Redfield MM, Jacobsen SJ, Burnett JC Jr, et al. Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic. JAMA. 2003; 289: 194-202.
-
(2003)
JAMA
, vol.289
, pp. 194-202
-
-
Redfield, M.M.1
Jacobsen, S.J.2
Burnett Jr, J.C.3
-
2
-
-
84861234413
-
Chronic inhibition of cGMP phosphodiesterase 5A improves diabetic cardiomyopathy: a randomized, controlled clinical trial using magnetic resonance imaging with myocardial tagging
-
Giannetta E, Isidori AM, Galea N, et al. Chronic inhibition of cGMP phosphodiesterase 5A improves diabetic cardiomyopathy: a randomized, controlled clinical trial using magnetic resonance imaging with myocardial tagging. Circulation. 2012; 125: 2323-33.
-
(2012)
Circulation
, vol.125
, pp. 2323-2333
-
-
Giannetta, E.1
Isidori, A.M.2
Galea, N.3
-
3
-
-
78349297565
-
Oxidative stress and diabetic complications
-
Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res. 2010; 107: 1058-70.
-
(2010)
Circ Res
, vol.107
, pp. 1058-1070
-
-
Giacco, F.1
Brownlee, M.2
-
4
-
-
33644766038
-
Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy
-
Shen X, Zheng S, Metreveli NS, et al. Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy. Diabetes. 2006; 55: 798- 805.
-
(2006)
Diabetes
, vol.55
, pp. 798-805
-
-
Shen, X.1
Zheng, S.2
Metreveli, N.S.3
-
5
-
-
33646520117
-
Cardiac contractile dysfunction in Lep/Lep obesity is accompanied by NADPH oxidase activation, oxidative modification of sarco(endo)plasmic reticulum Ca2+-ATPase and myosin heavy chain isozyme switch
-
Li SY, Yang X, Ceylan-Isik AF, et al. Cardiac contractile dysfunction in Lep/Lep obesity is accompanied by NADPH oxidase activation, oxidative modification of sarco(endo)plasmic reticulum Ca2+-ATPase and myosin heavy chain isozyme switch. Diabetologia. 2006; 49: 1434-46.
-
(2006)
Diabetologia
, vol.49
, pp. 1434-1446
-
-
Li, S.Y.1
Yang, X.2
Ceylan-Isik, A.F.3
-
6
-
-
34047158753
-
Reduced neuronal nitric oxide synthase expression contributes to cardiac oxidative stress and nitroso-redox imbalance in ob/ob mice
-
Saraiva RM, Minhas KM, Zheng M, et al. Reduced neuronal nitric oxide synthase expression contributes to cardiac oxidative stress and nitroso-redox imbalance in ob/ob mice. Nitric Oxide. 2007; 16: 331-8.
-
(2007)
Nitric Oxide
, vol.16
, pp. 331-338
-
-
Saraiva, R.M.1
Minhas, K.M.2
Zheng, M.3
-
7
-
-
84875450015
-
Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes
-
He C, Zhu H, Li H, et al. Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes. Diabetes. 2013; 62: 1270-81.
-
(2013)
Diabetes
, vol.62
, pp. 1270-1281
-
-
He, C.1
Zhu, H.2
Li, H.3
-
8
-
-
62449110463
-
Absence of autophagy results in reactive oxygen speciesdependent amplification of RLR signaling
-
Tal MC, Sasai M, Lee HK, et al. Absence of autophagy results in reactive oxygen speciesdependent amplification of RLR signaling. Proc Natl Acad Sci USA. 2009; 106: 2770-5.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2770-2775
-
-
Tal, M.C.1
Sasai, M.2
Lee, H.K.3
-
9
-
-
84867278754
-
Oxidative stress impairs autophagic flux in prion protein-deficient hippocampal cells
-
Oh JM, Choi EK, Carp RI, et al. Oxidative stress impairs autophagic flux in prion protein-deficient hippocampal cells. Autophagy. 2012; 8: 1448-61.
-
(2012)
Autophagy
, vol.8
, pp. 1448-1461
-
-
Oh, J.M.1
Choi, E.K.2
Carp, R.I.3
-
10
-
-
80053456372
-
Calorie restriction and resveratrol in cardiovascular health and disease
-
Dolinsky VW, Dyck JR. Calorie restriction and resveratrol in cardiovascular health and disease. Biochim Biophys Acta. 2011; 1812: 1477-89.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 1477-1489
-
-
Dolinsky, V.W.1
Dyck, J.R.2
-
11
-
-
79957532361
-
Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53
-
Zhang C, Feng Y, Qu S, et al. Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53. Cardiovasc Res. 2011; 90: 538-45.
-
(2011)
Cardiovasc Res
, vol.90
, pp. 538-545
-
-
Zhang, C.1
Feng, Y.2
Qu, S.3
-
12
-
-
77749254621
-
Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy
-
Sulaiman M, Matta MJ, Sunderesan NR, et al. Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy. Am J Physiol Heart Circ Physiol. 2010; 298: H833-43.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
, pp. H833-H843
-
-
Sulaiman, M.1
Matta, M.J.2
Sunderesan, N.R.3
-
13
-
-
77949357437
-
Cardioprotection by resveratrol: a novelmechanism via autophagy involving the mTORC2 pathway
-
Gurusamy N, Lekli I, Mukherjee S, et al. Cardioprotection by resveratrol: a novelmechanism via autophagy involving the mTORC2 pathway. Cardiovasc Res. 2010; 86: 103-12.
-
(2010)
Cardiovasc Res
, vol.86
, pp. 103-112
-
-
Gurusamy, N.1
Lekli, I.2
Mukherjee, S.3
-
14
-
-
67649118398
-
Rac1 is required for cardiomyocyte apoptosis during hyperglycemia
-
Shen E, Li Y, Li Y, et al. Rac1 is required for cardiomyocyte apoptosis during hyperglycemia. Diabetes. 2009; 58: 2386-95.
-
(2009)
Diabetes
, vol.58
, pp. 2386-2395
-
-
Shen, E.1
Li, Y.2
Li, Y.3
-
15
-
-
79959967420
-
The role of autophagy emerging in postinfarction cardiac remodelling
-
Kanamori H, Takemura G, Goto K, et al. The role of autophagy emerging in postinfarction cardiac remodelling. Cardiovasc Res. 2011; 91: 330-9.
-
(2011)
Cardiovasc Res
, vol.91
, pp. 330-339
-
-
Kanamori, H.1
Takemura, G.2
Goto, K.3
-
16
-
-
0018231715
-
Recommendations regarding quantitation in Mmode echocardiography: results of a survey of echocardiographic measurements
-
Sahn DJ, DeMaria A, Kisslo J, et al. Recommendations regarding quantitation in Mmode echocardiography: results of a survey of echocardiographic measurements. Circulation. 1978; 58: 1072-83.
-
(1978)
Circulation
, vol.58
, pp. 1072-1083
-
-
Sahn, D.J.1
DeMaria, A.2
Kisslo, J.3
-
17
-
-
25444448730
-
15-F(2t)-isoprostane exacerbates myocardial ischemia-reperfusion injury of isolated rat hearts
-
Xia Z, Kuo KH, Godin DV, et al. 15-F(2t)-isoprostane exacerbates myocardial ischemia-reperfusion injury of isolated rat hearts. Am J Physiol Heart Circ Physiol. 2005; 289: H1366-72.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
, pp. H1366-H1372
-
-
Xia, Z.1
Kuo, K.H.2
Godin, D.V.3
-
18
-
-
77951220203
-
Trypanosoma cruzi induces the reactive oxygen species-PARP-1-RelA pathway for up-regulation of cytokine expression in cardiomyocytes
-
Ba X, Gupta S, Davidson M, et al. Trypanosoma cruzi induces the reactive oxygen species-PARP-1-RelA pathway for up-regulation of cytokine expression in cardiomyocytes. J Biol Chem. 2010; 285: 11596-606.
-
(2010)
J Biol Chem
, vol.285
, pp. 11596-11606
-
-
Ba, X.1
Gupta, S.2
Davidson, M.3
-
19
-
-
33749570745
-
Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes
-
Hamacher-Brady A, Brady NR, Gottlieb RA. Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes. J Biol Chem. 2006; 281: 29776-87.
-
(2006)
J Biol Chem
, vol.281
, pp. 29776-29787
-
-
Hamacher-Brady, A.1
Brady, N.R.2
Gottlieb, R.A.3
-
20
-
-
84860204453
-
Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia
-
Eisfeld AK, Marcucci G, Liyanarachchi S, et al. Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia. Proc Natl Acad Sci USA. 2012; 109: 6668-73.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 6668-6673
-
-
Eisfeld, A.K.1
Marcucci, G.2
Liyanarachchi, S.3
-
22
-
-
0035914304
-
Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening
-
Grozinger CM, Chao ED, Blackwell HE, et al. Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening. J Biol Chem. 2001; 276: 38837-43.
-
(2001)
J Biol Chem
, vol.276
, pp. 38837-38843
-
-
Grozinger, C.M.1
Chao, E.D.2
Blackwell, H.E.3
-
23
-
-
84868628424
-
Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes
-
Russo SB, Baicu CF, Van Laer A, et al. Ceramide synthase 5 mediates lipid-induced autophagy and hypertrophy in cardiomyocytes. J Clin Invest. 2012; 122: 3919-30.
-
(2012)
J Clin Invest
, vol.122
, pp. 3919-3930
-
-
Russo, S.B.1
Baicu, C.F.2
Van Laer, A.3
-
24
-
-
79955658311
-
Myocardial autophagy activation and suppressed survival signaling is associated with insulin resistance in fructose-fed mice
-
Mellor KM, Bell JR, Young MJ, et al. Myocardial autophagy activation and suppressed survival signaling is associated with insulin resistance in fructose-fed mice. J Mol Cell Cardiol. 2011; 50: 1035-43.
-
(2011)
J Mol Cell Cardiol
, vol.50
, pp. 1035-1043
-
-
Mellor, K.M.1
Bell, J.R.2
Young, M.J.3
-
25
-
-
84872586081
-
Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy
-
Kim J, Kim YC, Fang C, et al. Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy. Cell. 2013; 152: 290-303.
-
(2013)
Cell
, vol.152
, pp. 290-303
-
-
Kim, J.1
Kim, Y.C.2
Fang, C.3
-
26
-
-
27944504351
-
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
Bjørkøy G, Lamark T, Brech A, et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol. 2005; 171: 603-14.
-
(2005)
J Cell Biol
, vol.171
, pp. 603-614
-
-
Bjørkøy, G.1
Lamark, T.2
Brech, A.3
-
27
-
-
79959385996
-
Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice
-
Xie Z, Lau K, Eby B, et al. Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice. Diabetes. 2011; 60: 1770-8.
-
(2011)
Diabetes
, vol.60
, pp. 1770-1778
-
-
Xie, Z.1
Lau, K.2
Eby, B.3
-
28
-
-
84856746125
-
Chronic Akt activation accentuates aginginduced cardiac hypertrophy and myocardial contractile dysfunction: role of autophagy
-
Hua Y, Zhang Y, Ceylan-Isik AF, et al. Chronic Akt activation accentuates aginginduced cardiac hypertrophy and myocardial contractile dysfunction: role of autophagy. Basic Res Cardiol. 2011; 106: 1173-91.
-
(2011)
Basic Res Cardiol
, vol.106
, pp. 1173-1191
-
-
Hua, Y.1
Zhang, Y.2
Ceylan-Isik, A.F.3
-
29
-
-
34547101726
-
Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of nitric oxide, thioredoxin, and heme oxygenase
-
Thirunavukkarasu M, Penumathsa SV, Koneru S, et al. Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of nitric oxide, thioredoxin, and heme oxygenase. Free Radic Biol Med. 2007; 43: 720-9.
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 720-729
-
-
Thirunavukkarasu, M.1
Penumathsa, S.V.2
Koneru, S.3
-
30
-
-
0033152292
-
Significance of myocytes with positive DNA in situ nick end-labeling (TUNEL) in hearts with dilated cardiomyopathy: not apoptosis but DNA repair
-
Kanoh M, Takemura G, Misao J, et al. Significance of myocytes with positive DNA in situ nick end-labeling (TUNEL) in hearts with dilated cardiomyopathy: not apoptosis but DNA repair. Circulation. 1999; 99: 2757-64.
-
(1999)
Circulation
, vol.99
, pp. 2757-2764
-
-
Kanoh, M.1
Takemura, G.2
Misao, J.3
-
31
-
-
77951157657
-
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
-
Kume S, Uzu T, Horiike K, et al. Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney. J Clin Invest. 2010; 120: 1043-55.
-
(2010)
J Clin Invest
, vol.120
, pp. 1043-1055
-
-
Kume, S.1
Uzu, T.2
Horiike, K.3
-
32
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A, Sweeney LB, Sturgill JF, et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science. 2004; 303: 2011-5.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
-
33
-
-
57749170458
-
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
-
Haberland M, Montgomery RL, Olson EN. The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet. 2009; 10: 32-42.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 32-42
-
-
Haberland, M.1
Montgomery, R.L.2
Olson, E.N.3
-
34
-
-
36448940798
-
FoxO3 controls autophagy in skeletal muscle in vivo
-
Mammucari C, Milan G, Romanello V, et al. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab. 2007; 6: 458-71.
-
(2007)
Cell Metab
, vol.6
, pp. 458-471
-
-
Mammucari, C.1
Milan, G.2
Romanello, V.3
-
35
-
-
7244255989
-
Role for Rab7 in maturation of late autophagic vacuoles
-
Jager S, Bucci C, Tanida I, et al. Role for Rab7 in maturation of late autophagic vacuoles. J Cell Sci. 2004; 117: 4837-48.
-
(2004)
J Cell Sci
, vol.117
, pp. 4837-4848
-
-
Jäger, S.1
Bucci, C.2
Tanida, I.3
-
36
-
-
84875438596
-
Rab7 silencing prevents l-opioid receptor lysosomal targeting and rescues opioid responsiveness to strengthen diabetic neuropathic pain therapy
-
Mousa SA, Shaqura M, Khalefa BI, et al. Rab7 silencing prevents l-opioid receptor lysosomal targeting and rescues opioid responsiveness to strengthen diabetic neuropathic pain therapy. Diabetes. 2013; 62: 1308-19.
-
(2013)
Diabetes
, vol.62
, pp. 1308-1319
-
-
Mousa, S.A.1
Shaqura, M.2
Khalefa, B.I.3
-
37
-
-
78650691023
-
Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvationinduced autophagy in cardiac myocytes
-
Hariharan N, Maejima Y, Nakae J, et al. Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvationinduced autophagy in cardiac myocytes. Circ Res. 2010; 107: 1470-82.
-
(2010)
Circ Res
, vol.107
, pp. 1470-1482
-
-
Hariharan, N.1
Maejima, Y.2
Nakae, J.3
|