Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction

Journal of the American College of Cardiology

Volumn 68, Issue 14, 2016, Pages 1557-1571

  Gupta, Shashi Kumar ^a   Foinquinos, Ariana ^a   Thum, Sabrina ^a   Remke, Janet ^a   Zimmer, Karina ^a   Bauters, Christophe ^b,c   de Groote, Pascal ^b   Boon, Reinier A ^d   de Windt, Leon J ^e   Preissl, Sebastian ^f   Hein, Lutz ^f   Batkai, Sandor ^a   Pinet, Florence ^b   Thum, Thomas ^a,g  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b LILLE UNIVERSITY HOSPITAL   (France)

^c INSTITUT PASTEUR DE LILLE   (France)

^d GOETHE UNIVERSITY   (Germany)

^e MAASTRICHT UNIVERSITY   (Netherlands)

^f UNIVERSITY OF FREIBURG   (Germany)

^g NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

aging; autophagy; circulating miRNA; MiR 22; p62

Indexed keywords

BIOLOGICAL MARKER; GREEN FLUORESCENT PROTEIN; MICRORNA; MICRORNA 22; PROTEIN P53; MIRN22 MICRORNA, HUMAN; MIRN22 MICRORNA, MOUSE;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; CARDIAC MUSCLE CELL; CARDIOVASCULAR MORTALITY; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GERIATRIC PATIENT; HEART INFARCTION; HIGH THROUGHPUT SCREENING; HUMAN; HYPERTROPHY; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; MAJOR CLINICAL STUDY; MOUSE; NEWBORN; NONHUMAN; PRECLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; SYSTOLIC HEART FAILURE; UPREGULATION; AGED; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CELL CULTURE; DISEASE MODEL; GENETICS; HEART FAILURE; MYOCARDIAL INFARCTION; PATHOLOGY; PHYSIOLOGY;

AGED; ANIMALS; AUTOPHAGY; BIOMARKERS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HEART FAILURE; HUMANS; MICE; MICRORNAS; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC;

EID: 84992153372     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2016.07.739     Document Type: Article

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