-
1
-
-
37849048003
-
Discovery of genes activated by the mitochondrial unfolded protein response (mtUPR) and cognate promoter elements
-
Aldridge, J.E., Horibe, T., Hoogenraad, N.J., Discovery of genes activated by the mitochondrial unfolded protein response (mtUPR) and cognate promoter elements. PLoS One, 2(9), 2007, e874.
-
(2007)
PLoS One
, vol.2
, Issue.9
, pp. e874
-
-
Aldridge, J.E.1
Horibe, T.2
Hoogenraad, N.J.3
-
2
-
-
84889100159
-
Loss of iron triggers PINK1/Parkin-independent mitophagy
-
Allen, G.F., Toth, R., James, J., Ganley, I.G., Loss of iron triggers PINK1/Parkin-independent mitophagy. EMBO Rep. 14:12 (2013), 1127–1135.
-
(2013)
EMBO Rep.
, vol.14
, Issue.12
, pp. 1127-1135
-
-
Allen, G.F.1
Toth, R.2
James, J.3
Ganley, I.G.4
-
3
-
-
84930634952
-
Mitochondria: a crossroads for lipid metabolism defect in neurodegeneration with brain iron accumulation diseases
-
Aoun, M., Tiranti, V., Mitochondria: a crossroads for lipid metabolism defect in neurodegeneration with brain iron accumulation diseases. Int. J. Biochem. Cell Biol. 63 (2015), 25–31.
-
(2015)
Int. J. Biochem. Cell Biol.
, vol.63
, pp. 25-31
-
-
Aoun, M.1
Tiranti, V.2
-
4
-
-
84943402350
-
Endosymbiosis and eukaryotic cell evolution
-
Archibald, J.M., Endosymbiosis and eukaryotic cell evolution. Curr. Biol. 25:19 (2015), R911–921.
-
(2015)
Curr. Biol.
, vol.25
, Issue.19
, pp. R911-921
-
-
Archibald, J.M.1
-
5
-
-
84906861963
-
Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin
-
Ashrafi, G., Schlehe, J.S., LaVoie, M.J., Schwarz, T.L., Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin. J. Cell Biol. 206:5 (2014), 655–670.
-
(2014)
J. Cell Biol.
, vol.206
, Issue.5
, pp. 655-670
-
-
Ashrafi, G.1
Schlehe, J.S.2
LaVoie, M.J.3
Schwarz, T.L.4
-
6
-
-
84897113087
-
Mitochondrial contagion induced by Parkin deficiency in Drosophila hearts and its containment by suppressing mitofusin
-
Bhandari, P., Song, M., Chen, Y., Burelle, Y., Dorn, G.W., Mitochondrial contagion induced by Parkin deficiency in Drosophila hearts and its containment by suppressing mitofusin. Circ. Res. 114:2 (2014), 257–265.
-
(2014)
Circ. Res.
, vol.114
, Issue.2
, pp. 257-265
-
-
Bhandari, P.1
Song, M.2
Chen, Y.3
Burelle, Y.4
Dorn, G.W.5
-
7
-
-
84959463045
-
Mitochondria-judges and executioners of cell death sentences
-
Bhola, P.D., Letai, A., Mitochondria-judges and executioners of cell death sentences. Mol. Cell 61:5 (2016), 695–704.
-
(2016)
Mol. Cell
, vol.61
, Issue.5
, pp. 695-704
-
-
Bhola, P.D.1
Letai, A.2
-
8
-
-
79959344616
-
PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function
-
Billia, F., Hauck, L., Konecny, F., Rao, V., Shen, J., Mak, T.W., PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function. Proc. Natl. Acad. Sci. U. S. A. 108:23 (2011), 9572–9577.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, Issue.23
, pp. 9572-9577
-
-
Billia, F.1
Hauck, L.2
Konecny, F.3
Rao, V.4
Shen, J.5
Mak, T.W.6
-
9
-
-
84903179483
-
The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
-
Bingol, B., Tea, J.S., Phu, L., Reichelt, M., Bakalarski, C.E., Song, Q., et al. The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy. Nature 510:7505 (2014), 370–375.
-
(2014)
Nature
, vol.510
, Issue.7505
, pp. 370-375
-
-
Bingol, B.1
Tea, J.S.2
Phu, L.3
Reichelt, M.4
Bakalarski, C.E.5
Song, Q.6
-
10
-
-
78049529676
-
Vps35 mediates vesicle transport between the mitochondria and peroxisomes
-
Braschi, E., Goyon, V., Zunino, R., Mohanty, A., Xu, L., McBride, H.M., Vps35 mediates vesicle transport between the mitochondria and peroxisomes. Curr. Biol. 20:14 (2010), 1310–1315.
-
(2010)
Curr. Biol.
, vol.20
, Issue.14
, pp. 1310-1315
-
-
Braschi, E.1
Goyon, V.2
Zunino, R.3
Mohanty, A.4
Xu, L.5
McBride, H.M.6
-
11
-
-
79954520907
-
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
-
Chan, N.C., Salazar, A.M., Pham, A.H., Sweredoski, M.J., Kolawa, N.J., Graham, R.L., et al. Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum. Mol. Genet. 20:9 (2011), 1726–1737.
-
(2011)
Hum. Mol. Genet.
, vol.20
, Issue.9
, pp. 1726-1737
-
-
Chan, N.C.1
Salazar, A.M.2
Pham, A.H.3
Sweredoski, M.J.4
Kolawa, N.J.5
Graham, R.L.6
-
12
-
-
0037455575
-
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
-
Chen, H., Detmer, S.A., Ewald, A.J., Griffin, E.E., Fraser, S.E., Chan, D.C., Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J. Cell Biol. 160:2 (2003), 189–200.
-
(2003)
J. Cell Biol.
, vol.160
, Issue.2
, pp. 189-200
-
-
Chen, H.1
Detmer, S.A.2
Ewald, A.J.3
Griffin, E.E.4
Fraser, S.E.5
Chan, D.C.6
-
13
-
-
84878629272
-
Proteomics, transcriptomics and lipidomics of exosomes and ectosomes
-
Choi, D.S., Kim, D.K., Kim, Y.K., Gho, Y.S., Proteomics, transcriptomics and lipidomics of exosomes and ectosomes. Proteomics 13:10–11 (2013), 1554–1571.
-
(2013)
Proteomics
, vol.13
, Issue.10-11
, pp. 1554-1571
-
-
Choi, D.S.1
Kim, D.K.2
Kim, Y.K.3
Gho, Y.S.4
-
14
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
Clark, I.E., Dodson, M.W., Jiang, C., Cao, J.H., Huh, J.R., Seol, J.H., et al. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 441:7097 (2006), 1162–1166.
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
Cao, J.H.4
Huh, J.R.5
Seol, J.H.6
-
15
-
-
84863838790
-
Membrane vesicle release in bacteria, eukaryotes, and archaea: a conserved yet underappreciated aspect of microbial life
-
Deatherage, B.L., Cookson, B.T., Membrane vesicle release in bacteria, eukaryotes, and archaea: a conserved yet underappreciated aspect of microbial life. Infect. Immun. 80:6 (2012), 1948–1957.
-
(2012)
Infect. Immun.
, vol.80
, Issue.6
, pp. 1948-1957
-
-
Deatherage, B.L.1
Cookson, B.T.2
-
16
-
-
84863707554
-
Mitochondrial roles and cytoprotection in chronic liver injury
-
Degli Esposti, D., Hamelin, J., Bosselut, N., Saffroy, R., Sebagh, M., Pommier, A., et al. Mitochondrial roles and cytoprotection in chronic liver injury. Biochem. Res. Int., 2012, 2012, 387626.
-
(2012)
Biochem. Res. Int.
, vol.2012
, pp. 387626
-
-
Degli Esposti, D.1
Hamelin, J.2
Bosselut, N.3
Saffroy, R.4
Sebagh, M.5
Pommier, A.6
-
17
-
-
78049467743
-
Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice
-
Ding, W.X., Li, M., Chen, X., Ni, H.M., Lin, C.W., Gao, W., et al. Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice. Gastroenterology 139:5 (2010), 1740–1752.
-
(2010)
Gastroenterology
, vol.139
, Issue.5
, pp. 1740-1752
-
-
Ding, W.X.1
Li, M.2
Chen, X.3
Ni, H.M.4
Lin, C.W.5
Gao, W.6
-
18
-
-
77955514158
-
Mitochondrial pruning by Nix and BNip3: an essential function for cardiac-expressed death factors
-
Dorn, G.W. 2nd, Mitochondrial pruning by Nix and BNip3: an essential function for cardiac-expressed death factors. J. Cardiovasc. Transl. Res. 3:4 (2010), 374–383.
-
(2010)
J. Cardiovasc. Transl. Res.
, vol.3
, Issue.4
, pp. 374-383
-
-
Dorn, G.W.1
-
19
-
-
84877788725
-
Elevated autophagic sequestration of mitochondria and lipid droplets in steatotic hepatocytes of chronic ethanol-treated rats: an immunohistochemical and electron microscopic study
-
Eid, N., Ito, Y., Maemura, K., Otsuki, Y., Elevated autophagic sequestration of mitochondria and lipid droplets in steatotic hepatocytes of chronic ethanol-treated rats: an immunohistochemical and electron microscopic study. J. Mol. Histol. 44:3 (2013), 311–326.
-
(2013)
J. Mol. Histol.
, vol.44
, Issue.3
, pp. 311-326
-
-
Eid, N.1
Ito, Y.2
Maemura, K.3
Otsuki, Y.4
-
20
-
-
84982938791
-
Ethanol-induced mitophagy in liver is associated with activation of the PINK1-Parkin pathway triggered by oxidative dna damage
-
Eid, N., Ito, Y., Horibe, A., Otsuki, Y., Ethanol-induced mitophagy in liver is associated with activation of the PINK1-Parkin pathway triggered by oxidative dna damage. Histol. Histopathol., 2016, 11747.
-
(2016)
Histol. Histopathol.
, pp. 11747
-
-
Eid, N.1
Ito, Y.2
Horibe, A.3
Otsuki, Y.4
-
21
-
-
84928695187
-
Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
-
Freischmidt, A., Wieland, T., Richter, B., Ruf, W., Schaeffer, V., Muller, K., et al. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nat. Neurosci. 18:5 (2015), 631–636.
-
(2015)
Nat. Neurosci.
, vol.18
, Issue.5
, pp. 631-636
-
-
Freischmidt, A.1
Wieland, T.2
Richter, B.3
Ruf, W.4
Schaeffer, V.5
Muller, K.6
-
22
-
-
80054844842
-
ER tubules mark sites of mitochondrial division
-
Friedman, J.R., Lackner, L.L., West, M., DiBenedetto, J.R., Nunnari, J., Voeltz, G.K., ER tubules mark sites of mitochondrial division. Science 334:6054 (2011), 358–362.
-
(2011)
Science
, vol.334
, Issue.6054
, pp. 358-362
-
-
Friedman, J.R.1
Lackner, L.L.2
West, M.3
DiBenedetto, J.R.4
Nunnari, J.5
Voeltz, G.K.6
-
23
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
Geisler, S., Holmstrom, K.M., Skujat, D., Fiesel, F.C., Rothfuss, O.C., Kahle, P.J., et al. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat. Cell Biol. 12:2 (2010), 119–131.
-
(2010)
Nat. Cell Biol.
, vol.12
, Issue.2
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
-
24
-
-
77957673363
-
The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations
-
Geisler, S., Holmstrom, K.M., Treis, A., Skujat, D., Weber, S.S., Fiesel, F.C., et al. The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations. Autophagy 6:7 (2010), 871–878.
-
(2010)
Autophagy
, vol.6
, Issue.7
, pp. 871-878
-
-
Geisler, S.1
Holmstrom, K.M.2
Treis, A.3
Skujat, D.4
Weber, S.S.5
Fiesel, F.C.6
-
25
-
-
80053917869
-
Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and production of interferon beta
-
Gleason, C.E., Ordureau, A., Gourlay, R., Arthur, J.S., Cohen, P., Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and production of interferon beta. J. Biol. Chem. 286:41 (2011), 35663–35674.
-
(2011)
J. Biol. Chem.
, vol.286
, Issue.41
, pp. 35663-35674
-
-
Gleason, C.E.1
Ordureau, A.2
Gourlay, R.3
Arthur, J.S.4
Cohen, P.5
-
26
-
-
84859428688
-
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
-
Greene, A.W., Grenier, K., Aguileta, M.A., Muise, S., Farazifard, R., Haque, M.E., et al. Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment. EMBO Rep. 13:4 (2012), 378–385.
-
(2012)
EMBO Rep.
, vol.13
, Issue.4
, pp. 378-385
-
-
Greene, A.W.1
Grenier, K.2
Aguileta, M.A.3
Muise, S.4
Farazifard, R.5
Haque, M.E.6
-
27
-
-
34548313686
-
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage
-
Griparic, L., Kanazawa, T., van der Bliek, A.M., Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage. J. Cell Biol. 178:5 (2007), 757–764.
-
(2007)
J. Cell Biol.
, vol.178
, Issue.5
, pp. 757-764
-
-
Griparic, L.1
Kanazawa, T.2
van der Bliek, A.M.3
-
28
-
-
79952228407
-
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
-
Guo, J.Y., Chen, H.Y., Mathew, R., Fan, J., Strohecker, A.M., Karsli-Uzunbas, G., et al. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev. 25:5 (2011), 460–470.
-
(2011)
Genes Dev.
, vol.25
, Issue.5
, pp. 460-470
-
-
Guo, J.Y.1
Chen, H.Y.2
Mathew, R.3
Fan, J.4
Strohecker, A.M.5
Karsli-Uzunbas, G.6
-
29
-
-
84861733247
-
Microtubule-associated protein 1 light chain 3 (LC3) interacts with Bnip3 protein to selectively remove endoplasmic reticulum and mitochondria via autophagy
-
Hanna, R.A., Quinsay, M.N., Orogo, A.M., Giang, K., Rikka, S., Gustafsson, A.B., Microtubule-associated protein 1 light chain 3 (LC3) interacts with Bnip3 protein to selectively remove endoplasmic reticulum and mitochondria via autophagy. J. Biol. Chem. 287:23 (2012), 19094–19104.
-
(2012)
J. Biol. Chem.
, vol.287
, Issue.23
, pp. 19094-19104
-
-
Hanna, R.A.1
Quinsay, M.N.2
Orogo, A.M.3
Giang, K.4
Rikka, S.5
Gustafsson, A.B.6
-
30
-
-
84951930787
-
The PINK1-Parkin mitochondrial ubiquitylation pathway drives a program of OPTN/NDP52 recruitment and TBK1 activation to promote mitophagy
-
Heo, J.M., Ordureau, A., Paulo, J.A., Rinehart, J., Harper, J.W., The PINK1-Parkin mitochondrial ubiquitylation pathway drives a program of OPTN/NDP52 recruitment and TBK1 activation to promote mitophagy. Mol. Cell 60:1 (2015), 7–20.
-
(2015)
Mol. Cell
, vol.60
, Issue.1
, pp. 7-20
-
-
Heo, J.M.1
Ordureau, A.2
Paulo, J.A.3
Rinehart, J.4
Harper, J.W.5
-
31
-
-
33746299692
-
Regulation of mitochondrial morphology through proteolytic cleavage of OPA1
-
Ishihara, N., Fujita, Y., Oka, T., Mihara, K., Regulation of mitochondrial morphology through proteolytic cleavage of OPA1. EMBO J. 25:13 (2006), 2966–2977.
-
(2006)
EMBO J.
, vol.25
, Issue.13
, pp. 2966-2977
-
-
Ishihara, N.1
Fujita, Y.2
Oka, T.3
Mihara, K.4
-
32
-
-
78649685455
-
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
-
Jin, S.M., Lazarou, M., Wang, C., Kane, L.A., Narendra, D.P., Youle, R.J., Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J. Cell Biol. 191:5 (2010), 933–942.
-
(2010)
J. Cell Biol.
, vol.191
, Issue.5
, pp. 933-942
-
-
Jin, S.M.1
Lazarou, M.2
Wang, C.3
Kane, L.A.4
Narendra, D.P.5
Youle, R.J.6
-
33
-
-
84887486172
-
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
-
Jin, S.M., Youle, R.J., The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria. Autophagy 9 (2013), 1750–1757.
-
(2013)
Autophagy
, vol.9
, pp. 1750-1757
-
-
Jin, S.M.1
Youle, R.J.2
-
34
-
-
84919775416
-
The mitochondrial unfolded protein response-synchronizing genomes
-
Jovaisaite, V., Auwerx, J., The mitochondrial unfolded protein response-synchronizing genomes. Curr. Opin. Cell Biol. 33 (2015), 74–81.
-
(2015)
Curr. Opin. Cell Biol.
, vol.33
, pp. 74-81
-
-
Jovaisaite, V.1
Auwerx, J.2
-
35
-
-
84913565821
-
Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain
-
Kageyama, Y., Hoshijima, M., Seo, K., Bedja, D., Sysa-Shah, P., Andrabi, S.A., et al. Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain. EMBO J. 33:23 (2014), 2798–2813.
-
(2014)
EMBO J.
, vol.33
, Issue.23
, pp. 2798-2813
-
-
Kageyama, Y.1
Hoshijima, M.2
Seo, K.3
Bedja, D.4
Sysa-Shah, P.5
Andrabi, S.A.6
-
36
-
-
84899539731
-
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
-
Kane, L.A., Lazarou, M., Fogel, A.I., Li, Y., Yamano, K., Sarraf, S.A., et al. PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. J. Cell Biol. 205:2 (2014), 143–153.
-
(2014)
J. Cell Biol.
, vol.205
, Issue.2
, pp. 143-153
-
-
Kane, L.A.1
Lazarou, M.2
Fogel, A.I.3
Li, Y.4
Yamano, K.5
Sarraf, S.A.6
-
37
-
-
84925940926
-
PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease
-
Kazlauskaite, A., Muqit, M.M., PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease. FEBS J. 282:2 (2015), 215–223.
-
(2015)
FEBS J.
, vol.282
, Issue.2
, pp. 215-223
-
-
Kazlauskaite, A.1
Muqit, M.M.2
-
38
-
-
84899421556
-
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
-
Kazlauskaite, A., Kondapalli, C., Gourlay, R., Campbell, D.G., Ritorto, M.S., Hofmann, K., et al. Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65. Biochem. J 460:1 (2014), 127–139.
-
(2014)
Biochem. J
, vol.460
, Issue.1
, pp. 127-139
-
-
Kazlauskaite, A.1
Kondapalli, C.2
Gourlay, R.3
Campbell, D.G.4
Ritorto, M.S.5
Hofmann, K.6
-
39
-
-
84938742614
-
Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation
-
Kazlauskaite, A., Martinez-Torres, R.J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., et al. Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation. EMBO Rep. 16:8 (2015), 939–954.
-
(2015)
EMBO Rep.
, vol.16
, Issue.8
, pp. 939-954
-
-
Kazlauskaite, A.1
Martinez-Torres, R.J.2
Wilkie, S.3
Kumar, A.4
Peltier, J.5
Gonzalez, A.6
-
40
-
-
79954622220
-
Mitophagy selectively degrades individual damaged mitochondria after photoirradiation
-
Kim, I., Lemasters, J.J., Mitophagy selectively degrades individual damaged mitochondria after photoirradiation. Antioxid. Redox Signal. 14 (2011), 1919–1928.
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 1919-1928
-
-
Kim, I.1
Lemasters, J.J.2
-
41
-
-
84922666062
-
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
-
Kirienko, N.V., Ausubel, F.M., Ruvkun, G., Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. U. S. A. 112:6 (2015), 1821–1826.
-
(2015)
Proc. Natl. Acad. Sci. U. S. A.
, vol.112
, Issue.6
, pp. 1821-1826
-
-
Kirienko, N.V.1
Ausubel, F.M.2
Ruvkun, G.3
-
42
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada, T., Asakawa, S., Hattori, N., Matsumine, H., Yamamura, Y., Minoshima, S., et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392:6676 (1998), 605–608.
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
-
43
-
-
84864267876
-
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
-
Kondapalli, C., Kazlauskaite, A., Zhang, N., Woodroof, H.I., Campbell, D.G., Gourlay, R., et al. PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol, 2(5), 2012, 120080.
-
(2012)
Open Biol
, vol.2
, Issue.5
, pp. 120080
-
-
Kondapalli, C.1
Kazlauskaite, A.2
Zhang, N.3
Woodroof, H.I.4
Campbell, D.G.5
Gourlay, R.6
-
44
-
-
3843075121
-
Structural basis of mitochondrial tethering by mitofusin complexes
-
Koshiba, T., Detmer, S.A., Kaiser, J.T., Chen, H., McCaffery, J.M., Chan, D.C., Structural basis of mitochondrial tethering by mitofusin complexes. Science 305:5685 (2004), 858–862.
-
(2004)
Science
, vol.305
, Issue.5685
, pp. 858-862
-
-
Koshiba, T.1
Detmer, S.A.2
Kaiser, J.T.3
Chen, H.4
McCaffery, J.M.5
Chan, D.C.6
-
45
-
-
84901751574
-
Ubiquitin is phosphorylated by PINK1 to activate parkin
-
Koyano, F., Okatsu, K., Kosako, H., Tamura, Y., Go, E., Kimura, M., et al. Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature 510:7503 (2014), 162–166.
-
(2014)
Nature
, vol.510
, Issue.7503
, pp. 162-166
-
-
Koyano, F.1
Okatsu, K.2
Kosako, H.3
Tamura, Y.4
Go, E.5
Kimura, M.6
-
46
-
-
84872283780
-
Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction
-
Kubli, D.A., Zhang, X., Lee, Y., Hanna, R.A., Quinsay, M.N., Nguyen, C.K., et al. Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction. J. Biol. Chem. 288:2 (2013), 915–926.
-
(2013)
J. Biol. Chem.
, vol.288
, Issue.2
, pp. 915-926
-
-
Kubli, D.A.1
Zhang, X.2
Lee, Y.3
Hanna, R.A.4
Quinsay, M.N.5
Nguyen, C.K.6
-
47
-
-
84857032953
-
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin
-
Lazarou, M., Jin, S.M., Kane, L.A., Youle, R.J., Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin. Dev. Cell 22:2 (2012), 320–333.
-
(2012)
Dev. Cell
, vol.22
, Issue.2
, pp. 320-333
-
-
Lazarou, M.1
Jin, S.M.2
Kane, L.A.3
Youle, R.J.4
-
48
-
-
84873045973
-
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
-
Lazarou, M., Narendra, D.P., Jin, S.M., Tekle, E., Banerjee, S., Youle, R.J., PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding. J. Cell Biol. 200:2 (2013), 163–172.
-
(2013)
J. Cell Biol.
, vol.200
, Issue.2
, pp. 163-172
-
-
Lazarou, M.1
Narendra, D.P.2
Jin, S.M.3
Tekle, E.4
Banerjee, S.5
Youle, R.J.6
-
49
-
-
84939804206
-
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
-
Lazarou, M., Sliter, D.A., Kane, L.A., Sarraf, S.A., Wang, C., Burman, J.L., et al. The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy. Nature 524:7565 (2015), 309–314.
-
(2015)
Nature
, vol.524
, Issue.7565
, pp. 309-314
-
-
Lazarou, M.1
Sliter, D.A.2
Kane, L.A.3
Sarraf, S.A.4
Wang, C.5
Burman, J.L.6
-
50
-
-
84898619521
-
MicroRNA-137 is a novel hypoxia-responsive microRNA that inhibits mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX
-
Li, W., Zhang, X., Zhuang, H., Chen, H.G., Chen, Y., Tian, W., et al. MicroRNA-137 is a novel hypoxia-responsive microRNA that inhibits mitophagy via regulation of two mitophagy receptors FUNDC1 and NIX. J. Biol. Chem. 289:15 (2014), 10691–10701.
-
(2014)
J. Biol. Chem.
, vol.289
, Issue.15
, pp. 10691-10701
-
-
Li, W.1
Zhang, X.2
Zhuang, H.3
Chen, H.G.4
Chen, Y.5
Tian, W.6
-
51
-
-
84928924502
-
USP30 deubiquitylates mitochondrial Parkin substrates and restricts apoptotic cell death
-
Liang, J.R., Martinez, A., Lane, J.D., Mayor, U., Clague, M.J., Urbe, S., USP30 deubiquitylates mitochondrial Parkin substrates and restricts apoptotic cell death. EMBO Rep. 16:5 (2015), 618–627.
-
(2015)
EMBO Rep.
, vol.16
, Issue.5
, pp. 618-627
-
-
Liang, J.R.1
Martinez, A.2
Lane, J.D.3
Mayor, U.4
Clague, M.J.5
Urbe, S.6
-
52
-
-
84876287362
-
Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice
-
Lin, C.W., Zhang, H., Li, M., Xiong, X., Chen, X., Chen, X., et al. Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice. J. Hepatol. 58:5 (2013), 993–999.
-
(2013)
J. Hepatol.
, vol.58
, Issue.5
, pp. 993-999
-
-
Lin, C.W.1
Zhang, H.2
Li, M.3
Xiong, X.4
Chen, X.5
Chen, X.6
-
53
-
-
84903817207
-
Receptor-mediated mitophagy in yeast and mammalian systems
-
Liu, L., Sakakibara, K., Chen, Q., Okamoto, K., Receptor-mediated mitophagy in yeast and mammalian systems. Cell Res. 24:7 (2014), 787–795.
-
(2014)
Cell Res.
, vol.24
, Issue.7
, pp. 787-795
-
-
Liu, L.1
Sakakibara, K.2
Chen, Q.3
Okamoto, K.4
-
54
-
-
84874639591
-
Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission
-
Loson, O.C., Song, Z., Chen, H., Chan, D.C., Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission. Mol. Biol. Cell 24:5 (2013), 659–667.
-
(2013)
Mol. Biol. Cell
, vol.24
, Issue.5
, pp. 659-667
-
-
Loson, O.C.1
Song, Z.2
Chen, H.3
Chan, D.C.4
-
55
-
-
77952419246
-
Mutations of optineurin in amyotrophic lateral sclerosis
-
Maruyama, H., Morino, H., Ito, H., Izumi, Y., Kato, H., Watanabe, Y., et al. Mutations of optineurin in amyotrophic lateral sclerosis. Nature 465:7295 (2010), 223–226.
-
(2010)
Nature
, vol.465
, Issue.7295
, pp. 223-226
-
-
Maruyama, H.1
Morino, H.2
Ito, H.3
Izumi, Y.4
Kato, H.5
Watanabe, Y.6
-
56
-
-
84978437500
-
Parkinson's disease-related proteins PINK1 and Parkin repress mitochondrial antigen presentation
-
Matheoud, D., Sugiura, A., Bellemare-Pelletier, A., Laplante, A., Rondeau, C., Chemali, M., et al. Parkinson's disease-related proteins PINK1 and Parkin repress mitochondrial antigen presentation. Cell 166:2 (2016), 314–327.
-
(2016)
Cell
, vol.166
, Issue.2
, pp. 314-327
-
-
Matheoud, D.1
Sugiura, A.2
Bellemare-Pelletier, A.3
Laplante, A.4
Rondeau, C.5
Chemali, M.6
-
57
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
-
Matsuda, N., Sato, S., Shiba, K., Okatsu, K., Saisho, K., Gautier, C.A., et al. PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J. Cell Biol. 189:2 (2010), 211–221.
-
(2010)
J. Cell Biol.
, vol.189
, Issue.2
, pp. 211-221
-
-
Matsuda, N.1
Sato, S.2
Shiba, K.3
Okatsu, K.4
Saisho, K.5
Gautier, C.A.6
-
58
-
-
84864310340
-
Matrix proteases in mitochondrial DNA function
-
Matsushima, Y., Kaguni, L.S., Matrix proteases in mitochondrial DNA function. Biochim. Biophys. Acta 1819:9–10 (2012), 1080–1087.
-
(2012)
Biochim. Biophys. Acta
, vol.1819
, Issue.9-10
, pp. 1080-1087
-
-
Matsushima, Y.1
Kaguni, L.S.2
-
59
-
-
84897863239
-
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
-
McLelland, G.L., Soubannier, V., Chen, C.X., McBride, H.M., Fon, E.A., Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control. EMBO J. 33:4 (2014), 282–295.
-
(2014)
EMBO J.
, vol.33
, Issue.4
, pp. 282-295
-
-
McLelland, G.L.1
Soubannier, V.2
Chen, C.X.3
McBride, H.M.4
Fon, E.A.5
-
60
-
-
84936132577
-
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
-
Murakawa, T., Yamaguchi, O., Hashimoto, A., Hikoso, S., Takeda, T., Oka, T., et al. Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation. Nat. Commun., 6, 2015, 7527.
-
(2015)
Nat. Commun.
, vol.6
, pp. 7527
-
-
Murakawa, T.1
Yamaguchi, O.2
Hashimoto, A.3
Hikoso, S.4
Takeda, T.5
Oka, T.6
-
61
-
-
78649300971
-
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
-
Narendra, D., Kane, L.A., Hauser, D.N., Fearnley, I.M., Youle, R.J., p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both. Autophagy 6:8 (2010), 1090–1106.
-
(2010)
Autophagy
, vol.6
, Issue.8
, pp. 1090-1106
-
-
Narendra, D.1
Kane, L.A.2
Hauser, D.N.3
Fearnley, I.M.4
Youle, R.J.5
-
62
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
Narendra, D.P., Jin, S.M., Tanaka, A., Suen, D.F., Gautier, C.A., Shen, J., et al. PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol., 8(1), 2010, e1000298.
-
(2010)
PLoS Biol.
, vol.8
, Issue.1
, pp. e1000298
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
-
63
-
-
38349023008
-
Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers
-
Neuspiel, M., Schauss, A.C., Braschi, E., Zunino, R., Rippstein, P., Rachubinski, R.A., et al. Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers. Curr. Biol. 18:2 (2008), 102–108.
-
(2008)
Curr. Biol.
, vol.18
, Issue.2
, pp. 102-108
-
-
Neuspiel, M.1
Schauss, A.C.2
Braschi, E.3
Zunino, R.4
Rippstein, P.5
Rachubinski, R.A.6
-
64
-
-
38449107710
-
Outer mitochondrial membrane protein degradation by the proteasome
-
discussion 14–20
-
Neutzner, A., Youle, R.J., Karbowski, M., Outer mitochondrial membrane protein degradation by the proteasome. Novartis Found. Symp. 287 (2007), 4–14 discussion 14–20.
-
(2007)
Novartis Found. Symp.
, vol.287
, pp. 4-14
-
-
Neutzner, A.1
Youle, R.J.2
Karbowski, M.3
-
65
-
-
84922794336
-
Phosphorylated ubiquitin chain is the genuine Parkin receptor
-
Okatsu, K., Koyano, F., Kimura, M., Kosako, H., Saeki, Y., Tanaka, K., et al. Phosphorylated ubiquitin chain is the genuine Parkin receptor. J. Cell Biol. 209:1 (2015), 111–128.
-
(2015)
J. Cell Biol.
, vol.209
, Issue.1
, pp. 111-128
-
-
Okatsu, K.1
Koyano, F.2
Kimura, M.3
Kosako, H.4
Saeki, Y.5
Tanaka, K.6
-
66
-
-
33947434544
-
OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis
-
Olichon, A., Elachouri, G., Baricault, L., Delettre, C., Belenguer, P., Lenaers, G., OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis. Cell Death Differ. 14:4 (2007), 682–692.
-
(2007)
Cell Death Differ.
, vol.14
, Issue.4
, pp. 682-692
-
-
Olichon, A.1
Elachouri, G.2
Baricault, L.3
Delettre, C.4
Belenguer, P.5
Lenaers, G.6
-
67
-
-
84929691103
-
Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy
-
Ordureau, A., Heo, J.M., Duda, D.M., Paulo, J.A., Olszewski, J.L., Yanishevski, D., et al. Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy. Proc. Natl. Acad. Sci. U. S. A. 112:21 (2015), 6637–6642.
-
(2015)
Proc. Natl. Acad. Sci. U. S. A.
, vol.112
, Issue.21
, pp. 6637-6642
-
-
Ordureau, A.1
Heo, J.M.2
Duda, D.M.3
Paulo, J.A.4
Olszewski, J.L.5
Yanishevski, D.6
-
68
-
-
84887466109
-
The protonophore CCCP interferes with lysosomal degradation of autophagic cargo in yeast and mammalian cells
-
Padman, B.S., Bach, M., Lucarelli, G., Prescott, M., Ramm, G., The protonophore CCCP interferes with lysosomal degradation of autophagic cargo in yeast and mammalian cells. Autophagy 9 (2013), 1862–1875.
-
(2013)
Autophagy
, vol.9
, pp. 1862-1875
-
-
Padman, B.S.1
Bach, M.2
Lucarelli, G.3
Prescott, M.4
Ramm, G.5
-
69
-
-
84892989225
-
SirT3 regulates the mitochondrial unfolded protein response
-
Papa, L., Germain, D., SirT3 regulates the mitochondrial unfolded protein response. Mol. Cell. Biol. 34:4 (2014), 699–710.
-
(2014)
Mol. Cell. Biol.
, vol.34
, Issue.4
, pp. 699-710
-
-
Papa, L.1
Germain, D.2
-
70
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
Park, J., Lee, S.B., Lee, S., Kim, Y., Song, S., Kim, S., et al. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441:7097 (2006), 1157–1161.
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
-
71
-
-
84873843566
-
Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons
-
Rakovic, A., Shurkewitsch, K., Seibler, P., Grunewald, A., Zanon, A., Hagenah, J., et al. Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons. J. Biol. Chem. 288:4 (2013), 2223–2237.
-
(2013)
J. Biol. Chem.
, vol.288
, Issue.4
, pp. 2223-2237
-
-
Rakovic, A.1
Shurkewitsch, K.2
Seibler, P.3
Grunewald, A.4
Zanon, A.5
Hagenah, J.6
-
72
-
-
84879674444
-
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
-
Riley, B.E., Lougheed, J.C., Callaway, K., Velasquez, M., Brecht, E., Nguyen, L., et al. Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases. Nat. Commun., 4, 2013, 1982.
-
(2013)
Nat. Commun.
, vol.4
, pp. 1982
-
-
Riley, B.E.1
Lougheed, J.C.2
Callaway, K.3
Velasquez, M.4
Brecht, E.5
Nguyen, L.6
-
73
-
-
84944441112
-
A Ubl/ubiquitin switch in the activation of Parkin
-
Sauve, V., Lilov, A., Seirafi, M., Vranas, M., Rasool, S., Kozlov, G., et al. A Ubl/ubiquitin switch in the activation of Parkin. EMBO J. 34:20 (2015), 2492–2505.
-
(2015)
EMBO J.
, vol.34
, Issue.20
, pp. 2492-2505
-
-
Sauve, V.1
Lilov, A.2
Seirafi, M.3
Vranas, M.4
Rasool, S.5
Kozlov, G.6
-
74
-
-
84937514081
-
Iron-starvation-induced mitophagy mediates lifespan extension upon mitochondrial stress in C. elegans
-
Schiavi, A., Maglioni, S., Palikaras, K., Shaik, A., Strappazzon, F., Brinkmann, V., et al. Iron-starvation-induced mitophagy mediates lifespan extension upon mitochondrial stress in C. elegans. Curr. Biol. 25:14 (2015), 1810–1822.
-
(2015)
Curr. Biol.
, vol.25
, Issue.14
, pp. 1810-1822
-
-
Schiavi, A.1
Maglioni, S.2
Palikaras, K.3
Shaik, A.4
Strappazzon, F.5
Brinkmann, V.6
-
75
-
-
67650219052
-
Nix directly binds to GABARAP: a possible crosstalk between apoptosis and autophagy
-
Schwarten, M., Mohrluder, J., Ma, P., Stoldt, M., Thielmann, Y., Stangler, T., et al. Nix directly binds to GABARAP: a possible crosstalk between apoptosis and autophagy. Autophagy 5:5 (2009), 690–698.
-
(2009)
Autophagy
, vol.5
, Issue.5
, pp. 690-698
-
-
Schwarten, M.1
Mohrluder, J.2
Ma, P.3
Stoldt, M.4
Thielmann, Y.5
Stangler, T.6
-
76
-
-
84975755192
-
Mitochondrial ROS signaling in organismal homeostasis
-
Shadel, G.S., Horvath, T.L., Mitochondrial ROS signaling in organismal homeostasis. Cell 163:3 (2015), 560–569.
-
(2015)
Cell
, vol.163
, Issue.3
, pp. 560-569
-
-
Shadel, G.S.1
Horvath, T.L.2
-
77
-
-
84891822234
-
Mutations in Fis1 disrupt orderly disposal of defective mitochondria
-
Shen, Q., Yamano, K., Head, B.P., Kawajiri, S., Cheung, J.T., Wang, C., et al. Mutations in Fis1 disrupt orderly disposal of defective mitochondria. Mol. Biol. Cell 25:1 (2014), 145–159.
-
(2014)
Mol. Biol. Cell
, vol.25
, Issue.1
, pp. 145-159
-
-
Shen, Q.1
Yamano, K.2
Head, B.P.3
Kawajiri, S.4
Cheung, J.T.5
Wang, C.6
-
78
-
-
84871891737
-
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
-
Shiba-Fukushima, K., Imai, Y., Yoshida, S., Ishihama, Y., Kanao, T., Sato, S., et al. PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy. Sci. Rep., 2, 2012, 1002.
-
(2012)
Sci. Rep.
, vol.2
, pp. 1002
-
-
Shiba-Fukushima, K.1
Imai, Y.2
Yoshida, S.3
Ishihama, Y.4
Kanao, T.5
Sato, S.6
-
79
-
-
84919629959
-
Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial Tethering
-
Shiba-Fukushima, K., Arano, T., Matsumoto, G., Inoshita, T., Yoshida, S., Ishihama, Y., et al. Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial Tethering. PLoS Genet., 10(12), 2014, e1004861.
-
(2014)
PLoS Genet.
, vol.10
, Issue.12
, pp. e1004861
-
-
Shiba-Fukushima, K.1
Arano, T.2
Matsumoto, G.3
Inoshita, T.4
Yoshida, S.5
Ishihama, Y.6
-
80
-
-
34548313688
-
OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L
-
Song, Z., Chen, H., Fiket, M., Alexander, C., Chan, D.C., OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L. J. Cell Biol. 178:5 (2007), 749–755.
-
(2007)
J. Cell Biol.
, vol.178
, Issue.5
, pp. 749-755
-
-
Song, Z.1
Chen, H.2
Fiket, M.3
Alexander, C.4
Chan, D.C.5
-
81
-
-
84856221632
-
A vesicular transport pathway shuttles cargo from mitochondria to lysosomes
-
Soubannier, V., McLelland, G.L., Zunino, R., Braschi, E., Rippstein, P., Fon, E.A., et al. A vesicular transport pathway shuttles cargo from mitochondria to lysosomes. Curr. Biol. 22:2 (2012), 135–141.
-
(2012)
Curr. Biol.
, vol.22
, Issue.2
, pp. 135-141
-
-
Soubannier, V.1
McLelland, G.L.2
Zunino, R.3
Braschi, E.4
Rippstein, P.5
Fon, E.A.6
-
82
-
-
84879980089
-
A molecular explanation for the recessive nature of parkin-linked Parkinson's disease
-
Spratt, D.E., Julio Martinez-Torres, R., Noh, Y.J., Mercier, P., Manczyk, N., Barber, K.R., et al. A molecular explanation for the recessive nature of parkin-linked Parkinson's disease. Nat. Commun., 4, 2013, 1983.
-
(2013)
Nat. Commun.
, vol.4
, pp. 1983
-
-
Spratt, D.E.1
Julio Martinez-Torres, R.2
Noh, Y.J.3
Mercier, P.4
Manczyk, N.5
Barber, K.R.6
-
83
-
-
79961239061
-
Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo
-
Sterky, F.H., Lee, S., Wibom, R., Olson, L., Larsson, N.G., Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo. Proc. Natl. Acad. Sci. U. S. A. 108:31 (2011), 12937–12942.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, Issue.31
, pp. 12937-12942
-
-
Sterky, F.H.1
Lee, S.2
Wibom, R.3
Olson, L.4
Larsson, N.G.5
-
84
-
-
84922506220
-
AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1
-
Strappazzon, F., Nazio, F., Corrado, M., Cianfanelli, V., Romagnoli, A., Fimia, G.M., et al. AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1. Cell Death Differ. 22:3 (2015), 419–432.
-
(2015)
Cell Death Differ.
, vol.22
, Issue.3
, pp. 419-432
-
-
Strappazzon, F.1
Nazio, F.2
Corrado, M.3
Cianfanelli, V.4
Romagnoli, A.5
Fimia, G.M.6
-
85
-
-
37549029702
-
Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1
-
Takatori, S., Ito, G., Iwatsubo, T., Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1. Neurosci. Lett. 430:1 (2008), 13–17.
-
(2008)
Neurosci. Lett.
, vol.430
, Issue.1
, pp. 13-17
-
-
Takatori, S.1
Ito, G.2
Iwatsubo, T.3
-
86
-
-
84879251778
-
Structure of parkin reveals mechanisms for ubiquitin ligase activation
-
Trempe, J.F., Sauve, V., Grenier, K., Seirafi, M., Tang, M.Y., Menade, M., et al. Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science 340:6139 (2013), 1451–1455.
-
(2013)
Science
, vol.340
, Issue.6139
, pp. 1451-1455
-
-
Trempe, J.F.1
Sauve, V.2
Grenier, K.3
Seirafi, M.4
Tang, M.Y.5
Menade, M.6
-
87
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente, E.M., Abou-Sleiman, P.M., Caputo, V., Muqit, M.M., Harvey, K., Gispert, S., et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304:5674 (2004), 1158–1160.
-
(2004)
Science
, vol.304
, Issue.5674
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
-
88
-
-
79960407069
-
Parkin interacts with Ambra1 to induce mitophagy
-
Van Humbeeck, C., Cornelissen, T., Hofkens, H., Mandemakers, W., Gevaert, K., De Strooper, B., et al. Parkin interacts with Ambra1 to induce mitophagy. J. Neurosci. 31:28 (2011), 10249–10261.
-
(2011)
J. Neurosci.
, vol.31
, Issue.28
, pp. 10249-10261
-
-
Van Humbeeck, C.1
Cornelissen, T.2
Hofkens, H.3
Mandemakers, W.4
Gevaert, K.5
De Strooper, B.6
-
89
-
-
79551603345
-
Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization
-
Van Laar, V.S., Arnold, B., Cassady, S.J., Chu, C.T., Burton, E.A., Berman, S.B., Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization. Hum. Mol. Genet. 20:5 (2011), 927–940.
-
(2011)
Hum. Mol. Genet.
, vol.20
, Issue.5
, pp. 927-940
-
-
Van Laar, V.S.1
Arnold, B.2
Cassady, S.J.3
Chu, C.T.4
Burton, E.A.5
Berman, S.B.6
-
90
-
-
84876213313
-
The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
-
Vincow, E.S., Merrihew, G., Thomas, R.E., Shulman, N.J., Beyer, R.P., MacCoss, M.J., et al. The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo. Proc. Natl. Acad. Sci. U. S. A. 110:16 (2013), 6400–6405.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, Issue.16
, pp. 6400-6405
-
-
Vincow, E.S.1
Merrihew, G.2
Thomas, R.E.3
Shulman, N.J.4
Beyer, R.P.5
MacCoss, M.J.6
-
91
-
-
84897472990
-
The role of AAA+ proteases in mitochondrial protein biogenesis, homeostasis and activity control
-
Voos, W., Ward, L.A., Truscott, K.N., The role of AAA+ proteases in mitochondrial protein biogenesis, homeostasis and activity control. Subcell. Biochem. 66 (2013), 223–263.
-
(2013)
Subcell. Biochem.
, vol.66
, pp. 223-263
-
-
Voos, W.1
Ward, L.A.2
Truscott, K.N.3
-
92
-
-
84871793725
-
Chaperone-protease networks in mitochondrial protein homeostasis
-
Voos, W., Chaperone-protease networks in mitochondrial protein homeostasis. Biochim. Biophys. Acta 1833:2 (2013), 388–399.
-
(2013)
Biochim. Biophys. Acta
, vol.1833
, Issue.2
, pp. 388-399
-
-
Voos, W.1
-
93
-
-
84954377019
-
Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes
-
Wang, W., Wang, X., Fujioka, H., Hoppel, C., Whone, A.L., Caldwell, M.A., et al. Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes. Nat. Med. 22:1 (2016), 54–63.
-
(2016)
Nat. Med.
, vol.22
, Issue.1
, pp. 54-63
-
-
Wang, W.1
Wang, X.2
Fujioka, H.3
Hoppel, C.4
Whone, A.L.5
Caldwell, M.A.6
-
94
-
-
84881477223
-
Structure of the human Parkin ligase domain in an autoinhibited state
-
Wauer, T., Komander, D., Structure of the human Parkin ligase domain in an autoinhibited state. EMBO J. 32:15 (2013), 2099–2112.
-
(2013)
EMBO J.
, vol.32
, Issue.15
, pp. 2099-2112
-
-
Wauer, T.1
Komander, D.2
-
95
-
-
79957949190
-
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
-
Wenzel, D.M., Lissounov, A., Brzovic, P.S., Klevit, R.E., UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids. Nature 474:7349 (2011), 105–108.
-
(2011)
Nature
, vol.474
, Issue.7349
, pp. 105-108
-
-
Wenzel, D.M.1
Lissounov, A.2
Brzovic, P.S.3
Klevit, R.E.4
-
96
-
-
84899789746
-
ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy
-
Wu, W., Tian, W., Hu, Z., Chen, G., Huang, L., Li, W., et al. ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy. EMBO Rep. 15:5 (2014), 566–575.
-
(2014)
EMBO Rep.
, vol.15
, Issue.5
, pp. 566-575
-
-
Wu, W.1
Tian, W.2
Hu, Z.3
Chen, G.4
Huang, L.5
Li, W.6
-
97
-
-
84887453820
-
PINK1 is degraded through the N-end rule pathway
-
Yamano, K., Youle, R.J., PINK1 is degraded through the N-end rule pathway. Autophagy 9:11 (2013), 1758–1769.
-
(2013)
Autophagy
, vol.9
, Issue.11
, pp. 1758-1769
-
-
Yamano, K.1
Youle, R.J.2
-
98
-
-
84898652320
-
Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
-
Yamano, K., Fogel, A.I., Wang, C., van der Bliek, A.M., Youle, R.J., Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. Elife, 3, 2014, e01612.
-
(2014)
Elife
, vol.3
, pp. e01612
-
-
Yamano, K.1
Fogel, A.I.2
Wang, C.3
van der Bliek, A.M.4
Youle, R.J.5
-
99
-
-
84954441494
-
Formation of mitochondrial outer membrane derived protrusions and vesicles in arabidopsis thaliana
-
Yamashita, A., Fujimoto, M., Katayama, K., Yamaoka, S., Tsutsumi, N., Arimura, S., Formation of mitochondrial outer membrane derived protrusions and vesicles in arabidopsis thaliana. PLoS One, 11(1), 2016, e0146717.
-
(2016)
PLoS One
, vol.11
, Issue.1
, pp. e0146717
-
-
Yamashita, A.1
Fujimoto, M.2
Katayama, K.3
Yamaoka, S.4
Tsutsumi, N.5
Arimura, S.6
-
100
-
-
80053430054
-
Spatiotemporally controlled initiation of Parkin-mediated mitophagy within single cells
-
Yang, J.Y., Yang, W.Y., Spatiotemporally controlled initiation of Parkin-mediated mitophagy within single cells. Autophagy 7 (2011), 1230–1238.
-
(2011)
Autophagy
, vol.7
, pp. 1230-1238
-
-
Yang, J.Y.1
Yang, W.Y.2
-
101
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
Zhang, H., Bosch-Marce, M., Shimoda, L.A., Tan, Y.S., Baek, J.H., Wesley, J.B., et al. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J. Biol. Chem. 283:16 (2008), 10892–10903.
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.16
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
Wesley, J.B.6
-
102
-
-
0037009521
-
A mitochondrial specific stress response in mammalian cells
-
Zhao, Q., Wang, J., Levichkin, I.V., Stasinopoulos, S., Ryan, M.T., Hoogenraad, N.J., A mitochondrial specific stress response in mammalian cells. EMBO J. 21:17 (2002), 4411–4419.
-
(2002)
EMBO J.
, vol.21
, Issue.17
, pp. 4411-4419
-
-
Zhao, Q.1
Wang, J.2
Levichkin, I.V.3
Stasinopoulos, S.4
Ryan, M.T.5
Hoogenraad, N.J.6
-
103
-
-
84897538368
-
Acute ethanol causes hepatic mitochondrial depolarization in mice: role of ethanol metabolism
-
Zhong, Z., Ramshesh, V.K., Rehman, H., Liu, Q., Theruvath, T.P., Krishnasamy, Y., et al. Acute ethanol causes hepatic mitochondrial depolarization in mice: role of ethanol metabolism. PLoS One, 9(3), 2014, e91308.
-
(2014)
PLoS One
, vol.9
, Issue.3
, pp. e91308
-
-
Zhong, Z.1
Ramshesh, V.K.2
Rehman, H.3
Liu, Q.4
Theruvath, T.P.5
Krishnasamy, Y.6
-
104
-
-
50149121528
-
The kinase domain of mitochondrial PINK1 faces the cytoplasm
-
Zhou, C., Huang, Y., Shao, Y., May, J., Prou, D., Perier, C., et al. The kinase domain of mitochondrial PINK1 faces the cytoplasm. Proc. Natl. Acad. Sci. U. S. A. 105:33 (2008), 12022–12027.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, Issue.33
, pp. 12022-12027
-
-
Zhou, C.1
Huang, Y.2
Shao, Y.3
May, J.4
Prou, D.5
Perier, C.6
-
105
-
-
9144261126
-
The PARK8 locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease-containing interval
-
Zimprich, A., Muller-Myhsok, B., Farrer, M., Leitner, P., Sharma, M., Hulihan, M., et al. The PARK8 locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease-containing interval. Am. J. Hum. Genet. 74:1 (2004), 11–19.
-
(2004)
Am. J. Hum. Genet.
, vol.74
, Issue.1
, pp. 11-19
-
-
Zimprich, A.1
Muller-Myhsok, B.2
Farrer, M.3
Leitner, P.4
Sharma, M.5
Hulihan, M.6
|