Abnormal kynurenine pathway of tryptophan catabolism in cardiovascular diseases

Cellular and Molecular Life Sciences

Volumn 74, Issue 16, 2017, Pages 2899-2916

  Song, Ping ^a   Ramprasath, Tharmarajan ^a   Wang, Huan ^a   Zou, Ming Hui ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Aging; Aortic aneurysm; Atherosclerosis; Diabetes; Kynurenine pathway; Obesity; Tryptophan

Indexed keywords

2 AMINO 4 (3' HYDROXYPHENYL) 4 HYDROXYBUTANOIC ACID; 4 AMINO N (3 CHLORO 4 FLUOROPHENYL) N' HYDROXY 1,2,5 OXADIAZOLE 3 CARBOXIMIDAMIDE; ANGIOTENSIN II; AROMATIC HYDROCARBON RECEPTOR; BFF 122; GAMMA INTERFERON; GSK 180; INDOLEAMINE 2,3 DIOXYGENASE; INDOLEAMINE 2,3 DIOXYGENASE 1; INDOLEAMINE 2,3 DIOXYGENASE 2; INDOLEAMINE 2,3 DIOXYGENASE INHIBITOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 2; KYNURENINASE; KYNURENINE; KYNURENINE 3 MONOOXYGENASE; KYNURENINE AMINOTRANSFERASE; METHOXYBENZOYALANINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NLG 919; OXYGENASE INHIBITOR; PF 04859989; PHENYL CYSTEINE SULFOXIDE; RO 61 8048; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; UPF 648; AMINOTRANSFERASE; ENZYME INHIBITOR; HYDROLASE; KYNURENINE-OXOGLUTARATE TRANSAMINASE; TRYPTOPHAN;

ABDOMINAL AORTIC ANEURYSM; AGING; APOPTOSIS; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; CELL ACTIVATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DIABETES MELLITUS; DOWN REGULATION; DRUG POTENCY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; IC50; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PULMONARY HYPERTENSION; REGULATORY T LYMPHOCYTE; REVIEW; SMOKING; TRYPTOPHAN METABOLISM; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; DRUG DEVELOPMENT; DRUG EFFECTS; METABOLISM; OBESITY; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION;

AGING; ANIMALS; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; DIABETES MELLITUS; DRUG DISCOVERY; ENDOTHELIAL CELLS; ENZYME INHIBITORS; HUMANS; HYDROLASES; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; KYNURENINE; KYNURENINE 3-MONOOXYGENASE; OBESITY; SIGNAL TRANSDUCTION; TRANSAMINASES; TRYPTOPHAN;

EID: 85015641459     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-017-2504-2     Document Type: Review

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