-
1
-
-
0035221101
-
Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy
-
Mellor AL, Sivakumar J, Chandler P, Smith K, Molina H, Mao D, et al. Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy. Nat Immunol (2001) 2:64-8. doi: 10.1038/83183
-
(2001)
Nat Immunol
, vol.2
, pp. 64-68
-
-
Mellor, A.L.1
Sivakumar, J.2
Chandler, P.3
Smith, K.4
Molina, H.5
Mao, D.6
-
2
-
-
0032555614
-
Prevention of allogeneic fetal rejection by tryptophan catabolism
-
Munn DH, Zhou M, Attwood JT, Bondarev I, Conway SJ, Marshall B, et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science (1998) 281:1191-3. doi:10.1126/science.281.5380.1191
-
(1998)
Science
, vol.281
, pp. 1191-1193
-
-
Munn, D.H.1
Zhou, M.2
Attwood, J.T.3
Bondarev, I.4
Conway, S.J.5
Marshall, B.6
-
3
-
-
34547643025
-
Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan
-
Metz R, Duhadaway JB, Kamasani U, Laury-Kleintop L, Muller AJ, Prendergast GC. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res (2007) 67(15):7082-7. doi:10.1158/0008-5472.CAN-07-1872
-
(2007)
Cancer Res
, vol.67
, Issue.15
, pp. 7082-7087
-
-
Metz, R.1
Duhadaway, J.B.2
Kamasani, U.3
Laury-Kleintop, L.4
Muller, A.J.5
Prendergast, G.C.6
-
4
-
-
84870990555
-
Effects of 1-methyltryptophan stereoisomers on IDO2 enzyme activity and IDO2-mediated arrest of human T cell proliferation
-
Qian F, Liao J, Villella J, Edwards R, Kalinski P, Lele S, et al. Effects of 1-methyltryptophan stereoisomers on IDO2 enzyme activity and IDO2-mediated arrest of human T cell proliferation. Cancer Immunol Immunother (2012) 61(11):2013-20. doi:10.1007/s00262-012-1265-x
-
(2012)
Cancer Immunol Immunother
, vol.61
, Issue.11
, pp. 2013-2020
-
-
Qian, F.1
Liao, J.2
Villella, J.3
Edwards, R.4
Kalinski, P.5
Lele, S.6
-
5
-
-
77954143054
-
1-l-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-d-methyltryptophan
-
Yuasa HJ, Ball HJ, Austin CJ, Hunt NH. 1-l-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-d-methyltryptophan. Comp Biochem Physiol B Biochem Mol Biol (2010) 157(1):10-15. doi:10.1016/j.cbpb.2010.04.006
-
(2010)
Comp Biochem Physiol B Biochem Mol Biol
, vol.157
, Issue.1
, pp. 10-15
-
-
Yuasa, H.J.1
Ball, H.J.2
Austin, C.J.3
Hunt, N.H.4
-
6
-
-
64849100126
-
Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases IDOs from monotremes and marsupials
-
Yuasa HJ, Ball HJ, Ho YF, Austin CJ, Whittington CM, Belov K, et al. Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases IDOs from monotremes and marsupials. Comp Biochem Physiol B Biochem Mol Biol (2009) 153(2):137-44. doi:10.1016/j.cbpb.2009.02.002
-
(2009)
Comp Biochem Physiol B Biochem Mol Biol
, vol.153
, Issue.2
, pp. 137-144
-
-
Yuasa, H.J.1
Ball, H.J.2
Ho, Y.F.3
Austin, C.J.4
Whittington, C.M.5
Belov, K.6
-
7
-
-
54849418903
-
IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism
-
Lob S, Konigsrainer A, Zieker D, Brucher BL, Rammensee HG, Opelz G, et al. IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism. Cancer Immunol Immunother (2009) 58(1):153-7. doi:10.1007/s00262-008-0513-6
-
(2009)
Cancer Immunol Immunother
, vol.58
, Issue.1
, pp. 153-157
-
-
Lob, S.1
Konigsrainer, A.2
Zieker, D.3
Brucher, B.L.4
Rammensee, H.G.5
Opelz, G.6
-
8
-
-
79957963254
-
Indoleamine 2,3-dioxygenase as a modifier of pathogenic inflammation in cancer and other inflammation-associated diseases
-
Prendergast GC, Chang MY, Mandik-Nayak L, Metz R, Muller AJ. Indoleamine 2,3-dioxygenase as a modifier of pathogenic inflammation in cancer and other inflammation-associated diseases. Curr Med Chem (2011) 18(15):2257-62. doi:10.2174/092986711795656072
-
(2011)
Curr Med Chem
, vol.18
, Issue.15
, pp. 2257-2262
-
-
Prendergast, G.C.1
Chang, M.Y.2
Mandik-Nayak, L.3
Metz, R.4
Muller, A.J.5
-
9
-
-
84903816506
-
Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer
-
Prendergast GC, Smith C, Thomas S, Mandik-Nayak L, Laury-Kleintop L, Metz R, et al. Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer. Cancer Immunol Immunother (2014) 63(7):721-35. doi:10.1007/s00262-014-1549-4
-
(2014)
Cancer Immunol Immunother
, vol.63
, Issue.7
, pp. 721-735
-
-
Prendergast, G.C.1
Smith, C.2
Thomas, S.3
Mandik-Nayak, L.4
Laury-Kleintop, L.5
Metz, R.6
-
10
-
-
84890522502
-
Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease
-
Fatokun AA, Hunt NH, Ball HJ. Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease. Amino Acids (2013) 45(6):1319-29. doi:10.1007/s00726-013-1602-1
-
(2013)
Amino Acids
, vol.45
, Issue.6
, pp. 1319-1329
-
-
Fatokun, A.A.1
Hunt, N.H.2
Ball, H.J.3
-
11
-
-
34249295962
-
Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice
-
Ball HJ, Sanchez-Perez A, Weiser S, Austin CJ, Astelbauer F, Miu J, et al. Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice. Gene (2007) 396(1):203-13. doi:10.1016/j.gene.2007.04.010
-
(2007)
Gene
, vol.396
, Issue.1
, pp. 203-213
-
-
Ball, H.J.1
Sanchez-Perez, A.2
Weiser, S.3
Austin, C.J.4
Astelbauer, F.5
Miu, J.6
-
12
-
-
37549022690
-
Evolution of vertebrate indoleamine 2,3-dioxygenases
-
Yuasa HJ, Takubo M, Takahashi A, Hasegawa T, Noma H, Suzuki T. Evolution of vertebrate indoleamine 2,3-dioxygenases. J Mol Evol (2007) 65(6):705-14. doi:10.1007/s00239-007-9049-1
-
(2007)
J Mol Evol
, vol.65
, Issue.6
, pp. 705-714
-
-
Yuasa, H.J.1
Takubo, M.2
Takahashi, A.3
Hasegawa, T.4
Noma, H.5
Suzuki, T.6
-
13
-
-
84879507035
-
Indoleamine 2,3-dioxygenases with very low catalytic activity are well conserved across kingdoms: IDOs of Basidiomycota
-
Yuasa HJ, Ball HJ. Indoleamine 2,3-dioxygenases with very low catalytic activity are well conserved across kingdoms: IDOs of Basidiomycota. Fungal Genet Biol (2013) 56:98-106. doi:10.1016/j.fgb.2013.03.003
-
(2013)
Fungal Genet Biol
, vol.56
, pp. 98-106
-
-
Yuasa, H.J.1
Ball, H.J.2
-
14
-
-
84872015298
-
Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis
-
Fukunaga M, Yamamoto Y, Kawasoe M, Arioka Y, Murakami Y, Hoshi M, et al. Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis. J Histochem Cytochem (2012) 60(11):854-60. doi:10.1369/0022155412458926
-
(2012)
J Histochem Cytochem
, vol.60
, Issue.11
, pp. 854-860
-
-
Fukunaga, M.1
Yamamoto, Y.2
Kawasoe, M.3
Arioka, Y.4
Murakami, Y.5
Hoshi, M.6
-
15
-
-
84893394819
-
The SOCS3-independent expression of IDO2 supports the homeostatic generation of T regulatory cells by human dendritic cells
-
Trabanelli S, Ocadlikova D, Ciciarello M, Salvestrini V, Lecciso M, Jandus C, et al. The SOCS3-independent expression of IDO2 supports the homeostatic generation of T regulatory cells by human dendritic cells. J Immunol (2014) 192(3):1231-40. doi:10.4049/jimmunol.1300720
-
(2014)
J Immunol
, vol.192
, Issue.3
, pp. 1231-1240
-
-
Trabanelli, S.1
Ocadlikova, D.2
Ciciarello, M.3
Salvestrini, V.4
Lecciso, M.5
Jandus, C.6
-
16
-
-
84856368231
-
CXCR3 ligands promote expression of functional indoleamine 2,3-dioxygenase in basal cell carcinoma keratinocytes
-
Lo BK, Jalili RB, Zloty D, Ghahary A, Cowan B, Dutz JP, et al. CXCR3 ligands promote expression of functional indoleamine 2,3-dioxygenase in basal cell carcinoma keratinocytes. Br J Dermatol (2011) 165(5):1030-6. doi:10.1111/j.1365-2133.2011.10489.x
-
(2011)
Br J Dermatol
, vol.165
, Issue.5
, pp. 1030-1036
-
-
Lo, B.K.1
Jalili, R.B.2
Zloty, D.3
Ghahary, A.4
Cowan, B.5
Dutz, J.P.6
-
17
-
-
77955850068
-
Novel 1-alkyl-tryptophan derivatives downregulate IDO1 and IDO2 mRNA expression induced by interferon-gamma in dendritic cells
-
Sun T, Chen XH, Tang ZD, Cai J, Wang XY, Wang SC, et al. Novel 1-alkyl-tryptophan derivatives downregulate IDO1 and IDO2 mRNA expression induced by interferon-gamma in dendritic cells. Mol Cell Biochem (2010) 342(1-2):29-34. doi:10.1007/s11010-010-0465-y
-
(2010)
Mol Cell Biochem
, vol.342
, Issue.1-2
, pp. 29-34
-
-
Sun, T.1
Chen, X.H.2
Tang, Z.D.3
Cai, J.4
Wang, X.Y.5
Wang, S.C.6
-
18
-
-
78751697961
-
Consequences of AhR activation in steady- state dendritic cells
-
Simones T, Shepherd DM. Consequences of AhR activation in steady- state dendritic cells. Toxicol Sci (2011) 119(2):293-307. doi:10.1093/toxsci/kfq354
-
(2011)
Toxicol Sci
, vol.119
, Issue.2
, pp. 293-307
-
-
Simones, T.1
Shepherd, D.M.2
-
19
-
-
80054041992
-
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
-
Opitz CA, Litzenburger UM, Sahm F, Ott M, Tritschler I, Trump S, et al. An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature (2011) 478(7368):197-203. doi:10.1038/nature10491
-
(2011)
Nature
, vol.478
, Issue.7368
, pp. 197-203
-
-
Opitz, C.A.1
Litzenburger, U.M.2
Sahm, F.3
Ott, M.4
Tritschler, I.5
Trump, S.6
-
20
-
-
50949098849
-
Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase
-
Vogel CF, Goth SR, Dong B, Pessah IN, Matsumura F. Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. Biochem Biophys Res Commun (2008) 375(3):331-5. doi:10.1016/j.bbrc.2008.07.156
-
(2008)
Biochem Biophys Res Commun
, vol.375
, Issue.3
, pp. 331-335
-
-
Vogel, C.F.1
Goth, S.R.2
Dong, B.3
Pessah, I.N.4
Matsumura, F.5
-
21
-
-
77953719954
-
Functional and phenotypic effects of AhR activation in inflammatory dendritic cells
-
Bankoti J, Rase B, Simones T, Shepherd DM. Functional and phenotypic effects of AhR activation in inflammatory dendritic cells. Toxicol Appl Pharmacol (2010) 246(1-2):18-28. doi:10.1016/j.taap.2010.03.013
-
(2010)
Toxicol Appl Pharmacol
, vol.246
, Issue.1-2
, pp. 18-28
-
-
Bankoti, J.1
Rase, B.2
Simones, T.3
Shepherd, D.M.4
-
22
-
-
43049103779
-
Expression of indoleamine 2,3-dioxygenase in metastatic pancreatic ductal adenocarcinoma recruits regulatory T cells to avoid immune detection
-
discussion 54-6
-
Witkiewicz A, Williams TK, Cozzitorto J, Durkan B, Showalter SL, Yeo CJ, et al. Expression of indoleamine 2,3-dioxygenase in metastatic pancreatic ductal adenocarcinoma recruits regulatory T cells to avoid immune detection. J Am Coll Surg (2008) 206(5):849-54; discussion 54-6. doi:10.1016/j.jamcollsurg.2007.12.014
-
(2008)
J Am Coll Surg
, vol.206
, Issue.5
, pp. 849-854
-
-
Witkiewicz, A.1
Williams, T.K.2
Cozzitorto, J.3
Durkan, B.4
Showalter, S.L.5
Yeo, C.J.6
-
23
-
-
64949113986
-
Genotyping and expression analysis of IDO2 in human pancreatic cancer: a novel, active target
-
discussion 7-9
-
Witkiewicz AK, Costantino CL, Metz R, Muller AJ, Prendergast GC, Yeo CJ, et al. Genotyping and expression analysis of IDO2 in human pancreatic cancer: a novel, active target. J Am Coll Surg (2009) 208(5):781-7. discussion 7-9, doi:10.1016/j.jamcollsurg.2008.12.018
-
(2009)
J Am Coll Surg
, vol.208
, Issue.5
, pp. 781-787
-
-
Witkiewicz, A.K.1
Costantino, C.L.2
Metz, R.3
Muller, A.J.4
Prendergast, G.C.5
Yeo, C.J.6
-
24
-
-
84896516675
-
IDO2 is critical for IDO1-mediated T cell regulation and exerts a non-redundant function in inflammation
-
Metz R, Smith C, Duhadaway JB, Chandler P, Baban B, Merlo LM, et al. IDO2 is critical for IDO1-mediated T cell regulation and exerts a non-redundant function in inflammation. Int Immunol (2014) 26(7):357-67. doi:10.1093/intimm/dxt073
-
(2014)
Int Immunol
, vol.26
, Issue.7
, pp. 357-367
-
-
Metz, R.1
Smith, C.2
Duhadaway, J.B.3
Chandler, P.4
Baban, B.5
Merlo, L.M.6
-
25
-
-
70149101645
-
IDO activates regulatory T cells and blocks their conversion into Th17-like T cells
-
Baban B, Chandler PR, Sharma MD, Pihkala J, Koni PA, Munn DH, et al. IDO activates regulatory T cells and blocks their conversion into Th17-like T cells. J Immunol (2009) 183(4):2475-83. doi:10.4049/jimmunol.0900986
-
(2009)
J Immunol
, vol.183
, Issue.4
, pp. 2475-2483
-
-
Baban, B.1
Chandler, P.R.2
Sharma, M.D.3
Pihkala, J.4
Koni, P.A.5
Munn, D.H.6
-
26
-
-
34848915783
-
Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase
-
Sharma MD, Baban B, Chandler P, Hou DY, Singh N, Yagita H, et al. Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase. J Clin Invest (2007) 117(9):2570-82. doi:10.1172/JCI31911
-
(2007)
J Clin Invest
, vol.117
, Issue.9
, pp. 2570-2582
-
-
Sharma, M.D.1
Baban, B.2
Chandler, P.3
Hou, D.Y.4
Singh, N.5
Yagita, H.6
-
27
-
-
67650351923
-
Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes
-
Sharma MD, Hou DY, Liu Y, Koni PA, Metz R, Chandler P, et al. Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes. Blood (2009) 113(24):6102-11. doi:10.1182/blood-2008-12-195354
-
(2009)
Blood
, vol.113
, Issue.24
, pp. 6102-6111
-
-
Sharma, M.D.1
Hou, D.Y.2
Liu, Y.3
Koni, P.A.4
Metz, R.5
Chandler, P.6
-
28
-
-
67449119139
-
Langerhans cell maturation and contact hypersensitivity are impaired in aryl hydrocarbon receptor-null mice
-
Jux B, Kadow S, Esser C. Langerhans cell maturation and contact hypersensitivity are impaired in aryl hydrocarbon receptor-null mice. J Immunol (2009) 182(11):6709-17. doi:10.4049/jimmunol.0713344
-
(2009)
J Immunol
, vol.182
, Issue.11
, pp. 6709-6717
-
-
Jux, B.1
Kadow, S.2
Esser, C.3
-
29
-
-
55949117914
-
Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase
-
Muller AJ, Sharma MD, Chandler PR, Duhadaway JB, Everhart ME, Johnson BA III, et al. Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase. Proc Natl Acad Sci U S A (2008) 105(44):17073-8. doi:10.1073/pnas.0806173105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.44
, pp. 17073-17078
-
-
Muller, A.J.1
Sharma, M.D.2
Chandler, P.R.3
Duhadaway, J.B.4
Everhart, M.E.5
Johnson B.A, I.I.I.6
-
30
-
-
35349002824
-
Indoleamine 2,3-dioxygenase activity is increased in patients with systemic lupus erythematosus and predicts disease activation in the sunny season
-
Pertovaara M, Hasan T, Raitala A, Oja SS, Yli-Kerttula U, Korpela M, et al. Indoleamine 2,3-dioxygenase activity is increased in patients with systemic lupus erythematosus and predicts disease activation in the sunny season. Clin Exp Immunol (2007) 150(2):274-8. doi:10.1111/j.1365-2249.2007.03480.x
-
(2007)
Clin Exp Immunol
, vol.150
, Issue.2
, pp. 274-278
-
-
Pertovaara, M.1
Hasan, T.2
Raitala, A.3
Oja, S.S.4
Yli-Kerttula, U.5
Korpela, M.6
-
31
-
-
80052608888
-
Indoleamine 2,3-dioxygenase-expressing peripheral cells in rheumatoid arthritis and systemic lupus erythematosus: a cross-sectional study
-
Furuzawa-Carballeda J, Lima G, Jakez-Ocampo J, Llorente L. Indoleamine 2,3-dioxygenase-expressing peripheral cells in rheumatoid arthritis and systemic lupus erythematosus: a cross-sectional study. Eur J Clin Invest (2011) 41(10):1037-46. doi:10.1111/j.1365-2362.2011.02491.x
-
(2011)
Eur J Clin Invest
, vol.41
, Issue.10
, pp. 1037-1046
-
-
Furuzawa-Carballeda, J.1
Lima, G.2
Jakez-Ocampo, J.3
Llorente, L.4
-
32
-
-
84903709090
-
Rheumatoid arthritis: who knows why regulatory T cells are defective in RA
-
Bernard NJ. Rheumatoid arthritis: who knows why regulatory T cells are defective in RA. IDO. Nat Rev Rheumatol (2014) 10(7):381. doi:10.1038/nrrheum.2014.96
-
(2014)
IDO. Nat Rev Rheumatol
, vol.10
, Issue.7
, pp. 381
-
-
Bernard, N.J.1
-
33
-
-
84896502247
-
IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis
-
Merlo LM, Pigott E, Duhadaway JB, Grabler S, Metz R, Prendergast GC, et al. IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis. J Immunol (2014) 92(5):2082-90. doi:10.4049/jimmunol.1303012
-
(2014)
J Immunol
, vol.92
, Issue.5
, pp. 2082-2090
-
-
Merlo, L.M.1
Pigott, E.2
Duhadaway, J.B.3
Grabler, S.4
Metz, R.5
Prendergast, G.C.6
-
34
-
-
67649216127
-
The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity
-
Scott GN, DuHadaway J, Pigott E, Ridge N, Prendergast GC, Muller AJ, et al. The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity. J Immunol (2009) 182(12):7509-17. doi:10.4049/jimmunol.0804328
-
(2009)
J Immunol
, vol.182
, Issue.12
, pp. 7509-7517
-
-
Scott, G.N.1
DuHadaway, J.2
Pigott, E.3
Ridge, N.4
Prendergast, G.C.5
Muller, A.J.6
-
35
-
-
84907398809
-
Treg cell function in rheumatoid arthritis is compromised by ctla-4 promoter methylation resulting in a failure to activate the indoleamine 2,3-dioxygenase pathway
-
Cribbs AP, Kennedy A, Penn H, Read JE, Amjadi P, Green P, et al. Treg cell function in rheumatoid arthritis is compromised by ctla-4 promoter methylation resulting in a failure to activate the indoleamine 2,3-dioxygenase pathway. Arthrit Rheumatol (2014) 66(9):2344-54. doi:10.1002/art.38715
-
(2014)
Arthrit Rheumatol
, vol.66
, Issue.9
, pp. 2344-2354
-
-
Cribbs, A.P.1
Kennedy, A.2
Penn, H.3
Read, J.E.4
Amjadi, P.5
Green, P.6
-
36
-
-
84907922428
-
Concurrent whole brain radiotherapy and short-course chloroquine in patients with brain metastases: a pilot trial
-
Eldredge HB, Denittis A, Duhadaway JB, Chernick M, Metz R, Prendergast GC. Concurrent whole brain radiotherapy and short-course chloroquine in patients with brain metastases: a pilot trial. J Radiat Oncol (2013) 2(3). doi:10.1007/s13566-013-0111-x
-
(2013)
J Radiat Oncol
, vol.2
, Issue.3
-
-
Eldredge, H.B.1
Denittis, A.2
Duhadaway, J.B.3
Chernick, M.4
Metz, R.5
Prendergast, G.C.6
-
37
-
-
33645115547
-
Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial
-
Sotelo J, Briceno E, Lopez-Gonzalez MA. Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial. Ann Intern Med (2006) 144(5):337-43. doi:10.7326/0003-4819-144-5-200603070-00008
-
(2006)
Ann Intern Med
, vol.144
, Issue.5
, pp. 337-343
-
-
Sotelo, J.1
Briceno, E.2
Lopez-Gonzalez, M.A.3
-
38
-
-
84857815702
-
Common genetic variation in the indoleamine-2,3-dioxygenase genes and antidepressant treatment outcome in major depressive disorder
-
Cutler JA, Rush AJ, McMahon FJ, Laje G. Common genetic variation in the indoleamine-2,3-dioxygenase genes and antidepressant treatment outcome in major depressive disorder. J Psychopharmacol (2012) 26(3):360-7. doi:10.1177/0269881111434622
-
(2012)
J Psychopharmacol
, vol.26
, Issue.3
, pp. 360-367
-
-
Cutler, J.A.1
Rush, A.J.2
McMahon, F.J.3
Laje, G.4
-
39
-
-
79952762101
-
Spontaneous cytotoxic T-Cell reactivity against indoleamine 2,3-dioxygenase-2
-
Sorensen RB, Kollgaard T, Andersen RS, van den Berg JH, Svane IM, Straten P, et al. Spontaneous cytotoxic T-Cell reactivity against indoleamine 2,3-dioxygenase-2. Cancer Res (2011) 71(6):2038-44. doi:10.1158/0008-5472.CAN-10-3403
-
(2011)
Cancer Res
, vol.71
, Issue.6
, pp. 2038-2044
-
-
Sorensen, R.B.1
Kollgaard, T.2
Andersen, R.S.3
van den Berg, J.H.4
Svane, I.M.5
Straten, P.6
-
40
-
-
59449103002
-
A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA
-
Yen MC, Lin CC, Chen YL, Huang SS, Yang HJ, Chang CP, et al. A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA. Clin Cancer Res (2009) 15(2):641-9. doi:10.1158/1078-0432.CCR-08-1988
-
(2009)
Clin Cancer Res
, vol.15
, Issue.2
, pp. 641-649
-
-
Yen, M.C.1
Lin, C.C.2
Chen, Y.L.3
Huang, S.S.4
Yang, H.J.5
Chang, C.P.6
-
41
-
-
79951820132
-
Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators
-
Sorensen RB, Hadrup SR, Svane IM, Hjortso MC, Thor Straten P, Andersen MH. Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators. Blood (2011) 117(7):2200-10. doi:10.1182/blood-2010-06-288498
-
(2011)
Blood
, vol.117
, Issue.7
, pp. 2200-2210
-
-
Sorensen, R.B.1
Hadrup, S.R.2
Svane, I.M.3
Hjortso, M.C.4
Thor Straten, P.5
Andersen, M.H.6
-
42
-
-
84886944226
-
Association of a functional Indoleamine 2,3-dioxygenase 2 genotype with specific immune responses
-
Kollgaard T, Klausen TW, Idorn M, Holmgaard RB, Straten PT, Andersen MH. Association of a functional Indoleamine 2,3-dioxygenase 2 genotype with specific immune responses. Oncoimmunology (2012) 1(4):441-7. doi:10.4161/onci.19654
-
(2012)
Oncoimmunology
, vol.1
, Issue.4
, pp. 441-447
-
-
Kollgaard, T.1
Klausen, T.W.2
Idorn, M.3
Holmgaard, R.B.4
Straten, P.T.5
Andersen, M.H.6
-
44
-
-
84880688294
-
IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan
-
Metz R, Rust S, Duhadaway JB, Mautino MR, Munn DH, Vahanian NN, et al. IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan. Oncoimmunology (2012) 1(9):1460-8. doi:10.4161/onci.21716
-
(2012)
Oncoimmunology
, vol.1
, Issue.9
, pp. 1460-1468
-
-
Metz, R.1
Rust, S.2
Duhadaway, J.B.3
Mautino, M.R.4
Munn, D.H.5
Vahanian, N.N.6
-
45
-
-
84866242667
-
IDO Is a nodal pathogenic driver of lung cancer and metastasis development
-
Smith C, Chang MY, Parker KH, Beury DW, Duhadaway JB, Flick HE, et al. IDO Is a nodal pathogenic driver of lung cancer and metastasis development. Cancer Discov (2012) 2(8):722-35. doi:10.1158/2159-8290.CD-12-0014
-
(2012)
Cancer Discov
, vol.2
, Issue.8
, pp. 722-735
-
-
Smith, C.1
Chang, M.Y.2
Parker, K.H.3
Beury, D.W.4
Duhadaway, J.B.5
Flick, H.E.6
-
46
-
-
84755160743
-
Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2
-
Austin CJ, Mailu BM, Maghzal GJ, Sanchez-Perez A, Rahlfs S, Zocher K, et al. Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2. Amino Acids (2010) 39(2):565-78. doi:10.1007/s00726-010-0475-9
-
(2010)
Amino Acids
, vol.39
, Issue.2
, pp. 565-578
-
-
Austin, C.J.1
Mailu, B.M.2
Maghzal, G.J.3
Sanchez-Perez, A.4
Rahlfs, S.5
Zocher, K.6
-
47
-
-
84870254950
-
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2
-
Bakmiwewa SM, Fatokun AA, Tran A, Payne RJ, Hunt NH, Ball HJ. Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2. Bioorg Med Chem Lett (2012) 22(24):7641-6. doi:10.1016/j.bmcl.2012.10.010
-
(2012)
Bioorg Med Chem Lett
, vol.22
, Issue.24
, pp. 7641-7646
-
-
Bakmiwewa, S.M.1
Fatokun, A.A.2
Tran, A.3
Payne, R.J.4
Hunt, N.H.5
Ball, H.J.6
-
48
-
-
84906310566
-
Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1
-
Pantouris G, Serys M, Yuasa HJ, Ball HJ, Mowat CG. Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1. Amino Acids (2014) 46(9):2155-63. doi:10.1007/s00726-014-1766-3
-
(2014)
Amino Acids
, vol.46
, Issue.9
, pp. 2155-2163
-
-
Pantouris, G.1
Serys, M.2
Yuasa, H.J.3
Ball, H.J.4
Mowat, C.G.5
-
49
-
-
77951718214
-
Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity
-
Liu X, Shin N, Koblish HK, Yang G, Wang Q, Wang K, et al. Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity. Blood (2010) 115(17):3520-30. doi:10.1182/blood-2009-09-246124
-
(2010)
Blood
, vol.115
, Issue.17
, pp. 3520-3530
-
-
Liu, X.1
Shin, N.2
Koblish, H.K.3
Yang, G.4
Wang, Q.5
Wang, K.6
-
50
-
-
81755161497
-
Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors
-
Meininger D, Zalameda L, Liu Y, Stepan LP, Borges L, McCarter JD, et al. Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors. Biochim Biophys Acta (2011) 1814(12):1947-54. doi:10.1016/j.bbapap.2011.07.023
-
(2011)
Biochim Biophys Acta
, vol.1814
, Issue.12
, pp. 1947-1954
-
-
Meininger, D.1
Zalameda, L.2
Liu, Y.3
Stepan, L.P.4
Borges, L.5
McCarter, J.D.6
-
51
-
-
41349088840
-
Levo- but not dextro-1-methyl tryptophan abrogates the IDO activity of human dendritic cells
-
Lob S, Konigsrainer A, Schafer R, Rammensee HG, Opelz G, Terness P. Levo- but not dextro-1-methyl tryptophan abrogates the IDO activity of human dendritic cells. Blood (2008) 111(4):2152-4. doi:10.1182/blood-2007-10-116111
-
(2008)
Blood
, vol.111
, Issue.4
, pp. 2152-2154
-
-
Lob, S.1
Konigsrainer, A.2
Schafer, R.3
Rammensee, H.G.4
Opelz, G.5
Terness, P.6
|