Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Lowe, Margaret M ^a   Mold, Jeff E ^a   Kanwar, Bittoo ^a   Huang, Yong ^b   Louie, Alexander ^b   Pollastri, Michael P ^c   Wang, Cuihua ^c   Patel, Gautam ^c   Franks, Diana G ^d   Schlezinger, Jennifer ^e   Sherr, David H ^e   Silverstone, Allen E ^f   Hahn, Mark E ^d   McCune, Joseph M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NORTHEASTERN UNIVERSITY   (United States)

^d WOODS HOLE OCEANOGRAPHIC INSTITUTION   (United States)

^e BOSTON UNIVERSITY   (United States)

^f SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYANTHRANILIC ACID; 3 HYDROXYKYNURENINE; AROMATIC HYDROCARBON RECEPTOR; CINNABARINIC ACID; CYTOCHROME P450 1A1; INTERLEUKIN 22; TRYPTOPHAN DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; AMINO ACID METABOLISM; ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; REGULATORY T LYMPHOCYTE; TH17 CELL; UPREGULATION; ZEBRA FISH;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 CYP1A1; HUMANS; INTERLEUKINS; LIGANDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXAZINES; RECEPTORS, ARYL HYDROCARBON; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; T-LYMPHOCYTES, REGULATORY; TH17 CELLS; TRYPTOPHAN;

EID: 84896825131     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087877     Document Type: Article

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