Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase

Journal of Experimental Medicine

Volumn 196, Issue 4, 2002, Pages 459-468

  Frumento, Guido ^a,d   Rotondo, Rita ^a   Tonetti, Michela ^b   Damonte, Gianluca ^b   Benatti, Umberto ^b   Ferrara, Giovanni Battista ^a,c  

^a UNIVERSITY OF GENOA   (Italy)

^b Section of Biochemistry   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d CENTRO DI BIOTECNOLOGIE AVANZATE   (Italy)

Author keywords

Indoleamine 2,3 dioxygenase; Kynurenine; Macrophages; T cell proliferation; Tryptophan

Indexed keywords

COLONY STIMULATING FACTOR 1; INDOLEAMINE 2,3 DIOXYGENASE; KYNURENINE; PICOLINIC ACID; QUINOLINIC ACID; TRYPTOPHAN; TRYPTOPHAN DERIVATIVE;

ARTICLE; CATABOLISM; CELL SPECIFICITY; ENZYME ACTIVITY; ENZYME PURIFICATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MALE; MICROENVIRONMENT; NATURAL KILLER CELL; NORMAL HUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; CELL DIVISION; CELLS, CULTURED; HUMANS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; KILLER CELLS, NATURAL; KYNURENINE; LEUKOCYTES, MONONUCLEAR; RABBITS; T-LYMPHOCYTES; TRYPTOPHAN; TRYPTOPHAN OXYGENASE;

EID: 0037136328     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20020121     Document Type: Article

References (17)

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