메뉴 건너뛰기




Volumn 278, Issue 22, 2011, Pages 4425-4434

Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats

Author keywords

aging; indoleamine 2,3 dioxygenase (IDO); kynurenine pathway; NAD +; tryptophan

Indexed keywords

ALPHA AMINO ACID; INDOLEAMINE 2,3 DIOXYGENASE; KYNURENINE; KYNURENINE ACID; NICOTINATE NUCLEOTIDE PYROPHOSPHORYLASE (CARBOXYLATING); PICOLINIC ACID; QUINOLINIC ACID; TRYPTOPHAN; TRYPTOPHAN 2,3 DIOXYGENASE; UNCLASSIFIED DRUG;

EID: 80155201282     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08366.x     Document Type: Article
Times cited : (95)

References (69)
  • 1
    • 0026043565 scopus 로고
    • Chronic quinolinic acid lesions in rats closely resemble Huntington's disease
    • Beal MF, Ferrante RJ, Swartz KJ, &, Kowall NW, (1991) Chronic quinolinic acid lesions in rats closely resemble Huntington's disease. J Neurosci 11, 1649-1659.
    • (1991) J Neurosci , vol.11 , pp. 1649-1659
    • Beal, M.F.1    Ferrante, R.J.2    Swartz, K.J.3    Kowall, N.W.4
  • 2
  • 3
    • 23044462498 scopus 로고    scopus 로고
    • Indoleamine 2,3 dioxygenase and quinolinic acid Immunoreactivity in Alzheimer's disease hippocampus
    • DOI 10.1111/j.1365-2990.2005.00655.x
    • Guillemin GJ, Brew BJ, Noonan CE, Takikawa O, &, Cullen KM, (2005) Indoleamine 2,3 dioxygenase and quinolinic acid immunoreactivity in Alzheimer's disease hippocampus. Neuropathol Appl Neurobiol 31, 395-404. (Pubitemid 41059860)
    • (2005) Neuropathology and Applied Neurobiology , vol.31 , Issue.4 , pp. 395-404
    • Guillemin, G.J.1    Brew, B.J.2    Noonan, C.E.3    Takikawa, O.4    Cullen, K.M.5
  • 4
    • 15844427653 scopus 로고    scopus 로고
    • Involvement of quinolinic acid in AIDS dementia complex
    • Guillemin GJ, Kerr SJ, &, Brew BJ, (2005) Involvement of quinolinic acid in AIDS dementia complex. Neurotox Res 7, 103-123.
    • (2005) Neurotox Res , vol.7 , pp. 103-123
    • Guillemin, G.J.1    Kerr, S.J.2    Brew, B.J.3
  • 5
    • 35948957337 scopus 로고    scopus 로고
    • Chronic HIV infection leads to an Alzheimer's disease like illness. Involvement of the kynurenine pathway
    • (Takai K. ed.), Elsevier, NY.
    • Guillemin GJ, &, Brew BJ, (2007) Chronic HIV infection leads to an Alzheimer's disease like illness. Involvement of the kynurenine pathway. In International Congress Series (, Takai K, ed.), pp. 324-334.Elsevier, NY.
    • (2007) International Congress Series , pp. 324-334
    • Guillemin, G.J.1    Brew, B.J.2
  • 7
    • 33744480316 scopus 로고    scopus 로고
    • + and NADH in cellular functions and cell death
    • DOI 10.2741/2038
    • Ying W, (2006) NAD+ and NADH in cellular functions and cell death. Front Biosci 11, 3129-3148. (Pubitemid 43800402)
    • (2006) Frontiers in Bioscience , vol.11 , Issue.SUPPL. 3 , pp. 3129-3148
    • Ying, W.1
  • 8
    • 34247195332 scopus 로고    scopus 로고
    • + and NADH in brain functions, brain diseases and brain aging
    • DOI 10.2741/2194
    • Ying W, (2007) NAD+ and NADH in brain functions, brain diseases and brain aging. Front Biosci 12, 1863-1888. (Pubitemid 46846813)
    • (2007) Frontiers in Bioscience , vol.12 , Issue.5 , pp. 1863-1888
    • Ying, W.1
  • 9
    • 1542346420 scopus 로고    scopus 로고
    • The new life of a centenarian: Signalling functions of NAD(P)
    • DOI 10.1016/j.tibs.2004.01.007, PII S0968000404000246
    • Berger F, Ramirez-Hernandez MH, &, Ziegler M, (2004) The new life of a centenarian: signalling functions of NAD(P). Trends Biochem Sci 29, 111-118. (Pubitemid 38314856)
    • (2004) Trends in Biochemical Sciences , vol.29 , Issue.3 , pp. 111-118
    • Berger, F.1    Ramirez-Hernandez, M.H.2    Ziegler, M.3
  • 10
    • 33847226657 scopus 로고    scopus 로고
    • An anti-aging drug today: From senescence-promoting genes to anti-aging pill
    • Blagosklonny MV, (2007) An anti-aging drug today: from senescence-promoting genes to anti-aging pill. Drug Discov Today 12, 218-224.
    • (2007) Drug Discov Today , vol.12 , pp. 218-224
    • Blagosklonny, M.V.1
  • 11
    • 25444463296 scopus 로고    scopus 로고
    • +
    • DOI 10.1111/j.1742-4658.2005.04864.x
    • Burkle A, (2005) Poly(ADP-ribose). The most elaborate metabolite of NAD+. FEBS J 272, 4576-4589. (Pubitemid 41372054)
    • (2005) FEBS Journal , vol.272 , Issue.18 , pp. 4576-4589
    • Burkle, A.1
  • 12
    • 9644270706 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl)ation and aging
    • DOI 10.1016/j.exger.2004.07.010, PII S0531556504002748
    • Burkle A, Beneke S, &, Muiras ML, (2004) Poly(ADP-ribosyl)ation and aging. Exp Gerontol 39, 1599-1601. (Pubitemid 39576131)
    • (2004) Experimental Gerontology , vol.39 , Issue.11-12 SPEC. ISS. , pp. 1599-1601
    • Burkle, A.1    Beneke, S.2    Muiras, M.-L.3
  • 15
    • 0028967644 scopus 로고
    • The role of indoleamine 2,3-dioxygenase in the anti-tumour activity of human interferon-gamma in vivo
    • Burke F, Knowles RG, East N, &, Balkwill FR, (1995) The role of indoleamine 2,3-dioxygenase in the anti-tumour activity of human interferon-gamma in vivo. Int J Cancer 60, 115-122.
    • (1995) Int J Cancer , vol.60 , pp. 115-122
    • Burke, F.1    Knowles, R.G.2    East, N.3    Balkwill, F.R.4
  • 16
    • 0034850590 scopus 로고    scopus 로고
    • Lipopolysaccharide induction of indoleamine 2,3-dioxygenase is mediated dominantly by an IFN-γ-independent mechanism
    • DOI 10.1002/1521-4141(200108)31:8<2313::AID-IMMU2313>3.0.CO;2-S
    • Fujigaki S, Saito K, Sekikawa K, Tone S, Takikawa O, Fujii H, Wada H, Noma A, &, Seishima M, (2001) Lipopolysaccharide induction of indoleamine 2,3-dioxygenase is mediated dominantly by an IFN-gamma-independent mechanism. Eur J Immunol 31, 2313-2318. (Pubitemid 32785349)
    • (2001) European Journal of Immunology , vol.31 , Issue.8 , pp. 2313-2318
    • Fujigaki, S.1    Saito, K.2    Sekikawa, K.3    Tone, S.4    Takikawa, O.5    Fujii, H.6    Wada, H.7    Noma, A.8    Seishima, M.9
  • 18
    • 34147115208 scopus 로고    scopus 로고
    • HIV-1 inhibits CD4+ T cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells
    • Boasso A, Herbeuval JP, Hardy AW, Anderson SA, Dolan MJ, Fuchs D, &, Shearer GM, (2006) HIV-1 inhibits CD4+ T cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells. Blood 109, 3351-3359.
    • (2006) Blood , vol.109 , pp. 3351-3359
    • Boasso, A.1    Herbeuval, J.P.2    Hardy, A.W.3    Anderson, S.A.4    Dolan, M.J.5    Fuchs, D.6    Shearer, G.M.7
  • 20
    • 0033998033 scopus 로고    scopus 로고
    • Induction of indolamine 2,3-dioxygenase in primary human macrophages by human immunodeficiency virus type 1 is strain dependent
    • DOI 10.1128/JVI.74.9.4110-4115.2000
    • Grant RS, Naif H, Thuruthyil SJ, Nasr N, Littlejohn T, Takikawa O, &, Kapoor V, (2000) Induction of indolamine 2,3-dioxygenase in primary human macrophages by human immunodeficiency virus type 1 is strain dependent. J Virol 74, 4110-4115. (Pubitemid 30214416)
    • (2000) Journal of Virology , vol.74 , Issue.9 , pp. 4110-4115
    • Grant, R.S.1    Naif, H.2    Thuruthyil, S.J.3    Nasr, N.4    Littlejohn, T.5    Takikawa, O.6    Kapoor, V.7
  • 21
    • 0000429092 scopus 로고
    • Reduced triphophopyridine-nucleotide requirement for the enzymatic formation of 3-hydroxykynurenine from L-kynurenine
    • De Castro F, Price J, &, Brown R, (1956) Reduced triphophopyridine- nucleotide requirement for the enzymatic formation of 3-hydroxykynurenine from L-kynurenine. J Am Chem Soc 78, 2904-2905.
    • (1956) J Am Chem Soc , vol.78 , pp. 2904-2905
    • De Castro, F.1    Price, J.2    Brown, R.3
  • 22
    • 3042731234 scopus 로고    scopus 로고
    • NMDA preconditioning protects against seizures and hippocampal neurotoxicity induced by quinolinic acid in mice
    • DOI 10.1111/j.0013-9580.2004.65203.x
    • Boeck CR, Ganzella M, Lottermann A, &, Vendite D, (2004) NMDA preconditioning protects against seizures and hippocampal neurotoxicity induced by quinolinic acid in mice. Epilepsia 45, 745-750. (Pubitemid 38890971)
    • (2004) Epilepsia , vol.45 , Issue.7 , pp. 745-750
    • Boeck, C.R.1    Ganzella, M.2    Lottermann, A.3    Vendite, D.4
  • 23
    • 31344463756 scopus 로고    scopus 로고
    • Kynurenic acid attenuates NMDA-induced pial arteriolar dilation in newborn pigs
    • DOI 10.1016/j.brainres.2005.11.033, PII S0006899305016276
    • Bari F, Nagy K, Guidetti P, Schwarcz R, Busija DW, &, Domoki F, (2006) Kynurenic acid attenuates NMDA-induced pial arteriolar dilation in newborn pigs. Brain Res 1069, 39-46. (Pubitemid 43145896)
    • (2006) Brain Research , vol.1069 , Issue.1 , pp. 39-46
    • Bari, F.1    Nagy, K.2    Guidetti, P.3    Schwarcz, R.4    Busija, D.W.5    Domoki, F.6
  • 24
    • 0026684818 scopus 로고
    • Developmental changes in brain kynurenic acid concentrations
    • Beal MF, Swartz K, &, Isacson O, (1992) Developmental changes in brain kynurenic acid concentrations. Dev Brain Res 68, 136-139.
    • (1992) Dev Brain Res , vol.68 , pp. 136-139
    • Beal, M.F.1    Swartz, K.2    Isacson, O.3
  • 25
    • 0022416845 scopus 로고
    • Quinolinic acid and other kynurenines in the central nervous system
    • DOI 10.1016/0306-4522(85)90063-6
    • Stone TW, &, Connick JH, (1985) Quinolinic acid and other kynurenines in the central nervous system. Neuroscience 15, 597-617. (Pubitemid 15236335)
    • (1985) Neuroscience , vol.15 , Issue.3 , pp. 597-617
    • Stone, T.W.1    Connick, J.H.2
  • 26
    • 0036690151 scopus 로고    scopus 로고
    • Endogenous kynurenines as targets for drug discovery and development
    • DOI 10.1038/nrd870
    • Stone TW, &, Darlington LG, (2002) Endogenous kynurenines as targets for drug discovery and development. Nat Rev Drug Discov 1, 609-620. (Pubitemid 37361524)
    • (2002) Nature Reviews Drug Discovery , vol.1 , Issue.8 , pp. 609-620
    • Stone, T.W.1    Darlington, L.G.2
  • 27
    • 0036378826 scopus 로고    scopus 로고
    • Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease
    • Guillemin GJ, &, Brew BJ, (2002) Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease. Redox Rep 7, 199-206.
    • (2002) Redox Rep , vol.7 , pp. 199-206
    • Guillemin, G.J.1    Brew, B.J.2
  • 28
    • 27344457006 scopus 로고    scopus 로고
    • Quinolinic acid selectively induces apoptosis of human astocytes: Potential role in AIDS dementia complex
    • Guillemin GJ, Wang L, &, Brew BJ, (2005) Quinolinic acid selectively induces apoptosis of human astocytes: potential role in AIDS dementia complex. J Neuroinflammation 2, 16.
    • (2005) J Neuroinflammation , vol.2 , pp. 16
    • Guillemin, G.J.1    Wang, L.2    Brew, B.J.3
  • 29
    • 67651228062 scopus 로고    scopus 로고
    • Effects of Kynurenine pathway metabolites on intracellular NAD+ synthesis and cell death in human primary astrocytes and neurons
    • Braidy N, Grant R, Brew BJ, Adams S, Jayasena T, &, Guillemin GJ, (2009) Effects of Kynurenine pathway metabolites on intracellular NAD+ synthesis and cell death in human primary astrocytes and neurons. IJTR 2, 61-69.
    • (2009) IJTR , vol.2 , pp. 61-69
    • Braidy, N.1    Grant, R.2    Brew, B.J.3    Adams, S.4    Jayasena, T.5    Guillemin, G.J.6
  • 30
    • 70349754448 scopus 로고    scopus 로고
    • Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons
    • Braidy N, Grant R, Adams S, Brew BJ, &, Guillemin G, (2009) Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons. Neurotox Res 16, 77-86.
    • (2009) Neurotox Res , vol.16 , pp. 77-86
    • Braidy, N.1    Grant, R.2    Adams, S.3    Brew, B.J.4    Guillemin, G.5
  • 31
    • 0025456905 scopus 로고
    • Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors
    • Patneau D, &, Mayer M, (1990) Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors. J Neurosci 10, 2385-2399.
    • (1990) J Neurosci , vol.10 , pp. 2385-2399
    • Patneau, D.1    Mayer, M.2
  • 32
    • 0028018814 scopus 로고
    • Picolinic acid blocks the neurotoxic but not the neuroexcitant properties of quinolinic acid in the rat brain: Evidence from turning behaviour and tyrosine hydroxylase immunohistochemistry
    • DOI 10.1016/0306-4522(94)90438-3
    • Beninger RJ, Colton AM, Ingles JL, Jhamandas K, &, Boegman RJ, (1994) Picolinic acid blocks the neurotoxic but not the neuroexcitant properties of quinolinic acid in the rat brain: evidence from turning behaviour and tyrosine hydroxylase immunohistochemistry. Neuroscience 61, 603-612. (Pubitemid 24240308)
    • (1994) Neuroscience , vol.61 , Issue.3 , pp. 603-612
    • Beninger, R.J.1
  • 33
    • 0024633844 scopus 로고
    • How old is old?
    • Coleman P, (1989) How old is old? Neurobiol Aging 10, 115.
    • (1989) Neurobiol Aging , vol.10 , pp. 115
    • Coleman, P.1
  • 34
    • 24044433596 scopus 로고    scopus 로고
    • The effect of age on the enzyme activities of tryptophan metabolism along the kynurenine pathway in rats
    • DOI 10.1016/j.cccn.2005.04.013, PII S0009898105002536
    • Comai S, Costa CV, Ragazzi E, Bertazzo A, &, Allegri G, (2005) The effect of age on the enzyme activities of tryptophan metabolism along the kynurenine pathway in rats. Clin Chim Acta 360, 67-80. (Pubitemid 41225395)
    • (2005) Clinica Chimica Acta , vol.360 , Issue.1-2 , pp. 67-80
    • Comai, S.1    Costa, C.V.L.2    Ragazzi, E.3    Bertazzo, A.4    Allegri, G.5
  • 35
    • 0016619603 scopus 로고
    • Relationship between tryptophan metabolism and vitamin B6 and nicotinamide in aged subjects
    • Crepaldi G, Allegri G, De Antoni A, Costa C, &, Muggeo M, (1975) Relationship between tryptophan metabolism and vitamin B6 and nicotinamide in aged subjects. Acta Vitaminol Enzymol 29, 140-144.
    • (1975) Acta Vitaminol Enzymol , vol.29 , pp. 140-144
    • Crepaldi, G.1    Allegri, G.2    De Antoni, A.3    Costa, C.4    Muggeo, M.5
  • 36
    • 76949089290 scopus 로고    scopus 로고
    • The extended life span of Drosophila melanogaster eye color (white and vermilion) mutants with impaired formation of kynurenine
    • Oxenkrug G, (2010) The extended life span of Drosophila melanogaster eye color (white and vermilion) mutants with impaired formation of kynurenine. J Neural Transm 117, 23-26.
    • (2010) J Neural Transm , vol.117 , pp. 23-26
    • Oxenkrug, G.1
  • 37
    • 4043180519 scopus 로고    scopus 로고
    • Increasing production of homocysteine and neopterin and degradation of tryptophan with older age
    • DOI 10.1016/j.clinbiochem.2004.02.007, PII S0009912004000578
    • Frick B, Schroecksnadel K, Neurauter G, Leblhuber F, &, Fuchs D, (2004) Increasing production of homocysteine and neopterin and degradation of tryptophan with older age. Clin Biochem 37, 684-687. (Pubitemid 39078460)
    • (2004) Clinical Biochemistry , vol.37 , Issue.8 , pp. 684-687
    • Frick, B.1    Schroecksnadel, K.2    Neurauter, G.3    Leblhuber, F.4    Fuchs, D.5
  • 38
    • 0028265462 scopus 로고
    • Role of serotonin in the pathophysiology of depression: Focus on the serotonin transporter
    • Owens MJ, &, Nemeroff CB, (1994) Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. Clin Chem 40, 288-295. (Pubitemid 24072594)
    • (1994) Clinical Chemistry , vol.40 , Issue.2 , pp. 288-295
    • Owens, M.J.1    Nemeroff, C.B.2
  • 39
    • 0024061102 scopus 로고
    • Cellular immune activation in the brain and human immunodeficiency virus infection
    • Fuchs D, Werner E, Dierich M, &, Wachter H, (1988) Cellular immune activation in the brain and human immunodeficiency virus infection. Ann Neurol 24, 289.
    • (1988) Ann Neurol , vol.24 , pp. 289
    • Fuchs, D.1    Werner, E.2    Dierich, M.3    Wachter, H.4
  • 40
    • 0033058001 scopus 로고    scopus 로고
    • Kynurenine metabolism in Alzheimer's disease
    • DOI 10.1007/s007020050149
    • Baran H, Jellinger K, &, Deecke L, (1999) Kynurenine metabolism in Alzheimer's disease. J Neural Transm 106, 165-181. (Pubitemid 29137514)
    • (1999) Journal of Neural Transmission , vol.106 , Issue.2 , pp. 165-181
    • Baran, H.1    Jellinger, K.2    Deecke, L.3
  • 43
    • 0021262777 scopus 로고
    • The excitotoxin quinolinic acid is present in the brain of several mammals and its cortical content increases during the aging process
    • DOI 10.1016/0304-3940(84)90385-9
    • Moroni F, Lombardi G, Moneti G, &, Aldinio C, (1984) The excitotoxin quinolinic acid is present in the brain of several mammals and its cortical content increases during the aging process. Neurosci Lett 47, 51-55. (Pubitemid 14111333)
    • (1984) Neuroscience Letters , vol.47 , Issue.1 , pp. 51-55
    • Moroni, F.1    Lombardi, G.2    Moneti, G.3    Aldinio, C.4
  • 44
    • 23844467167 scopus 로고    scopus 로고
    • 2-microglobulin changes
    • DOI 10.1159/000086295
    • Kepplinger B, Baran H, Kainz A, Ferraz-Leite H, Newcombe J, &, Kalina P, (2005) Age-related increase of kynurenic acid in human cerebrospinal fluid-IgG and beta2-microglobulin changes. Neurosignals 14, 126-135. (Pubitemid 41160299)
    • (2005) NeuroSignals , vol.14 , Issue.3 , pp. 126-135
    • Kepplinger, B.1    Baran, H.2    Kainz, A.3    Ferraz-Leite, H.4    Newcombe, J.5    Kalina, P.6
  • 49
  • 50
    • 3042842506 scopus 로고    scopus 로고
    • Altered NMDA receptor expression in renal toxicity: Protection with a receptor antagonist
    • DOI 10.1111/j.1523-1755.2004.00718.x
    • Leung J, Marphis T, Craver RD, &, Silverstein DM, (2004) Altered NMDA receptor expression in renal toxicity: protection with a receptor antagonist. Kidney Int 66, 167-176. (Pubitemid 38870092)
    • (2004) Kidney International , vol.66 , Issue.1 , pp. 167-176
    • Leung, J.C.1    Marphis, T.2    Craver, R.D.3    Silverstein, D.M.4
  • 51
    • 34248357083 scopus 로고    scopus 로고
    • Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery
    • DOI 10.1517/14728222.11.5.695
    • Khan JA, Forouhar F, Tao X, &, Tong L, (2007) Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery. Expert Opin Ther Targets 11, 695-705. (Pubitemid 46730083)
    • (2007) Expert Opinion on Therapeutic Targets , vol.11 , Issue.5 , pp. 695-705
    • Khan, J.A.1    Forouhar, F.2    Tao, X.3    Tong, L.4
  • 53
    • 33744475759 scopus 로고    scopus 로고
    • Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage
    • Kolthur-Seetharam U, Dantzer F, McBurney M, de Murcia G, &, Sassone-Corsi P, (2006) Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP1 in response to DNA damage. Cell Cycle 5, 873-877. (Pubitemid 44145583)
    • (2006) Cell Cycle , vol.5 , Issue.8 , pp. 873-877
    • Kolthur-Seetharam, U.1    Dantzer, F.2    McBurney, M.W.3    De Murcia, G.4    Sassone-Corsi, P.5
  • 54
    • 34547607850 scopus 로고    scopus 로고
    • Nicotinamide adenine dinucleotide: Beyond a redox coenzyme
    • DOI 10.1039/b706887e
    • Lin H, (2007) Nicotinamide adenine dinucleotide: beyond a redox coenzyme. Org Biomol Chem 5, 2541-2554. (Pubitemid 47192304)
    • (2007) Organic and Biomolecular Chemistry , vol.5 , Issue.16 , pp. 2541-2554
    • Lin, H.1
  • 55
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • DOI 10.1038/nrd2060, PII NRD2060
    • Baur JA, &, Sinclair DA, (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 5, 493-506. (Pubitemid 44136961)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.6 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 56
    • 0037160097 scopus 로고    scopus 로고
    • Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast Sir2 and human SIRT1
    • DOI 10.1074/jbc.M205670200
    • Bitterman KJ, Anderson RM, Cohen HY, Latorre-Esteves M, &, Sinclair DA, (2002) Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J Biol Chem 277, 45099-45107. (Pubitemid 36159111)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.47 , pp. 45099-45107
    • Bitterman, K.J.1    Anderson, R.M.2    Cohen, H.Y.3    Latorre-Esteves, M.4    Sinclair, D.A.5
  • 57
    • 0034257161 scopus 로고    scopus 로고
    • Astroglia and glutamate in physiology and pathology: Aspects on glutamate transport, glutamate-induced cell swelling and gap-junction communication
    • DOI 10.1016/S0197-0186(00)00033-4, PII S0197018600000334
    • Hansson E, Muyderman H, Leonova J, Allansson L, Sinclair J, Blomstrand F, Thorlin T, Nilsson M, &, Ronnback L, (2000) Astroglia and glutamate in physiology and pathology: aspects on glutamate transport, glutamate-induced cell swelling and gap-junction communication. Neurochem Int 37, 317-329. (Pubitemid 30254164)
    • (2000) Neurochemistry International , vol.37 , Issue.2-3 , pp. 317-329
    • Hansson, E.1    Muyderman, H.2    Leonova, J.3    Allansson, L.4    Sinclair, J.5    Blomstrand, F.6    Thorlin, T.7    Nilsson, M.8    Ronnback, L.9
  • 60
    • 4344590155 scopus 로고    scopus 로고
    • Small molecules that regulate lifespan: Evidence for xenohormesis
    • DOI 10.1111/j.1365-2958.2004.04209.x
    • Lamming DW, Wood JG, &, Sinclair DA, (2004) Small molecules that regulate lifespan: evidence for xenohormesis. Mol Microbiol 53, 1003-1009. (Pubitemid 39120424)
    • (2004) Molecular Microbiology , vol.53 , Issue.4 , pp. 1003-1009
    • Lamming, D.W.1    Wood, J.G.2    Sinclair, D.A.3
  • 61
    • 48349144852 scopus 로고    scopus 로고
    • Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending lifespan
    • Pearson K, Baur J, Lewis K, Peshkin L, Price N, Labinskyy N, Swindell W, Kamara D, Minor R, Perez E, et al. (2008) Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending lifespan. Cell Metab 8, 157-168.
    • (2008) Cell Metab , vol.8 , pp. 157-168
    • Pearson, K.1    Baur, J.2    Lewis, K.3    Peshkin, L.4    Price, N.5    Labinskyy, N.6    Swindell, W.7    Kamara, D.8    Minor, R.9    Perez, E.10
  • 62
    • 22744450382 scopus 로고    scopus 로고
    • Toward a unified theory of caloric restriction and longevity regulation
    • DOI 10.1016/j.mad.2005.03.019, PII S0047637405000874
    • Sinclair D, (2005) Toward a unified theory of calorie restriction and longevity regulation. Mech Ageing Dev 126, 987-1002. (Pubitemid 41033180)
    • (2005) Mechanisms of Ageing and Development , vol.126 , Issue.9 SPEC. ISS. , pp. 987-1002
    • Sinclair, D.A.1
  • 63
    • 0026316550 scopus 로고
    • Divergence of biological and chronological aging: Evidence from rodent studies
    • Collier TJ, &, Coleman PD, (1991) Divergence of biological and chronological aging: evidence from rodent studies. Neurobiol Aging 12, 685-693.
    • (1991) Neurobiol Aging , vol.12 , pp. 685-693
    • Collier, T.J.1    Coleman, P.D.2
  • 65
    • 0036467928 scopus 로고    scopus 로고
    • Concurrent quantification of quinolinic, picolinic, and nicotinic acids using electron-capture negative-ion gas chromatography - Mass spectrometry
    • DOI 10.1006/abio.2001.5490
    • Smythe GA, Braga O, Brew BJ, Grant RS, Guillemin GJ, Kerr SJ, &, Walker DW, (2002) Concurrent quantification of quinolinic, picolinic, and nicotinic acids using electron-capture negative-ion gas chromatography-mass spectrometry. Anal Biochem 301, 21-26. (Pubitemid 34113674)
    • (2002) Analytical Biochemistry , vol.301 , Issue.1 , pp. 21-26
    • Smythe, G.A.1    Braga, O.2    Brew, B.J.3    Grant, R.S.4    Guillemin, G.J.5    Kerr, S.J.6    Walker, D.W.7
  • 66
    • 0028587045 scopus 로고
    • Kynurenic acid, an endogenous glutamate antagonist, in SHR and WKY rats: Possible role in central blood pressure regulation
    • Kapoor V, Kapoor R, &, Chalmers J, (1994) Kynurenic acid, an endogenous glutamate antagonist, in SHR and WKY rats: possible role in central blood pressure regulation. Clin Exp Pharmacol Physiol 21, 891-896.
    • (1994) Clin Exp Pharmacol Physiol , vol.21 , pp. 891-896
    • Kapoor, V.1    Kapoor, R.2    Chalmers, J.3
  • 67
    • 0023766046 scopus 로고
    • Quantification of 3-hydroxykynurenine in brain by high-performance liquid chromatography and electrochemical detection
    • Heyes MP, &, Quearry BJ, (1988) Quantification of 3-hydroxykynurenine in brain by high-performance liquid chromatography and electrochemical detection. J Chromatogr 428, 340-344.
    • (1988) J Chromatogr , vol.428 , pp. 340-344
    • Heyes, M.P.1    Quearry, B.J.2
  • 68
    • 0023013615 scopus 로고
    • Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase
    • Takikawa O, Yoshida R, Kido R, &, Hayaishi O, (1986) Tryptophan degredation in mice initiated by indoleamine 2,3-dioxygenase. J Biol Chem 261, 3648-3653. (Pubitemid 17200663)
    • (1986) Journal of Biological Chemistry , vol.261 , Issue.8 , pp. 3648-3653
    • Takikawa, O.1    Yoshida, R.2    Kido, R.3    Hayaishi, O.4
  • 69
    • 0001333396 scopus 로고
    • A microsomal iron-porphyrin activator of rat liver tryptophan pyrrolase
    • Feigelson P, &, Greengard O, (1961) A microsomal iron-porphyrin activator of rat liver tryptophan pyrrolase. J Biol Chem 236, 153-157.
    • (1961) J Biol Chem , vol.236 , pp. 153-157
    • Feigelson, P.1    Greengard, O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.