Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV

Bioscience Reports

Volumn 31, Issue 5, 2011, Pages 323-332

  Han, Qian ^a   Robinson, Howard ^b   Cai, Tao ^c   Tagle, Danilo A ^d   Li, Jianyong ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

^c NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^d NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

Aspartate aminotransferase; Crystal structure; Kynurenic acid; Kynurenine; Kynurenine aminotransferase; Oxo acid

Indexed keywords

ASPARTATE AMINOTRANSFERASE ISOENZYME 2; COMPLEMENTARY DNA; KYNURENIC ACID; KYNURENINE AMINOTRANSFERASE; OXOACID; RECOMBINANT ENZYME;

AMINO ACID SYNTHESIS; ARTICLE; BIOCHEMISTRY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTALLOGRAPHY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; MOUSE; NEUROMODULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL; BRAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; KYNURENIC ACID; MICE; MITOCHONDRIAL PROTEINS; TRANSAMINASES;

ESCHERICHIA COLI; MAMMALIA; RATTUS;

EID: 80155145533     PISSN: 01448463     EISSN: None     Source Type: Journal    
DOI: 10.1042/BSR20100117     Document Type: Article

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