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Volumn 144, Issue 6, 2017, Pages 968-975

Translational applications of adult stem cell-derived organoids

Author keywords

Adult stem cells; Cancer; Disease modelling; Organoids

Indexed keywords

ADULT STEM CELL; ARTICLE; BIOBANK; CANCER GROWTH; CANCER THERAPY; CELL CULTURE; COCULTURE; CYTOPLASM; DISEASE MODEL; GENETIC DISORDER; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOTHERAPY; IN VITRO STUDY; MALIGNANT NEOPLASM; NONHUMAN; PERSONALIZED MEDICINE; PRIORITY JOURNAL; REGENERATIVE MEDICINE; ADULT; CYTOLOGY; NEOPLASMS; TRANSLATIONAL RESEARCH;

EID: 85015268570     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.140566     Document Type: Article
Times cited : (106)

References (85)
  • 2
  • 9
    • 79960990066 scopus 로고    scopus 로고
    • R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/betacatenin signaling
    • Carmon, K. S., Gong, X., Lin, Q., Thomas, A. and Liu, Q. (2011). R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/betacatenin signaling. Proc. Natl. Acad. Sci. USA 108, 11452-11457.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 11452-11457
    • Carmon, K.S.1    Gong, X.2    Lin, Q.3    Thomas, A.4    Liu, Q.5
  • 12
    • 84975275212 scopus 로고    scopus 로고
    • Modeling development and disease with organoids
    • Clevers, H. (2016). Modeling development and disease with organoids. Cell 165, 1586-1597.
    • (2016) Cell , vol.165 , pp. 1586-1597
    • Clevers, H.1
  • 13
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and disease
    • Clevers, H. and Nusse, R. (2012). Wnt/beta-catenin signaling and disease. Cell 149, 1192-1205.
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 15
    • 84971557656 scopus 로고    scopus 로고
    • Zika virus depletes neural progenitors in human cerebral organoids through activation of the innate immune receptor TLR3
    • Dang, J., Tiwari, S. K., Lichinchi, G., Qin, Y., Patil, V. S., Eroshkin, A. M. and Rana, T. M. (2016). Zika virus depletes neural progenitors in human cerebral organoids through activation of the innate immune receptor TLR3. Cell Stem Cell 19, 258-265.
    • (2016) Cell Stem Cell , vol.19 , pp. 258-265
    • Dang, J.1    Tiwari, S.K.2    Lichinchi, G.3    Qin, Y.4    Patil, V.S.5    Eroshkin, A.M.6    Rana, T.M.7
  • 24
    • 79751489596 scopus 로고    scopus 로고
    • Molecular genetics of colorectal cancer
    • Fearon, E. R. (2011). Molecular genetics of colorectal cancer. Annu. Rev. Pathol. 6, 479-507.
    • (2011) Annu. Rev. Pathol , vol.6 , pp. 479-507
    • Fearon, E.R.1
  • 25
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon, E. R. and Vogelstein, B. (1990). A genetic model for colorectal tumorigenesis. Cell 61, 759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 28
    • 84906093308 scopus 로고    scopus 로고
    • Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon
    • Fukuda, M., Mizutani, T., Mochizuki, W., Matsumoto, T., Nozaki, K., Sakamaki, Y., Ichinose, S., Okada, Y., Tanaka, T., Watanabe, M. et al. (2014). Small intestinal stem cell identity is maintained with functional Paneth cells in heterotopically grafted epithelium onto the colon. Genes Dev. 28, 1752-1757.
    • (2014) Genes Dev , vol.28 , pp. 1752-1757
    • Fukuda, M.1    Mizutani, T.2    Mochizuki, W.3    Matsumoto, T.4    Nozaki, K.5    Sakamaki, Y.6    Ichinose, S.7    Okada, Y.8    Tanaka, T.9    Watanabe, M.10
  • 35
    • 84942121762 scopus 로고    scopus 로고
    • Modeling mouse and human development using organoid cultures
    • Huch, M. and Koo, B.-K. (2015). Modeling mouse and human development using organoid cultures. Development 142, 3113-3125.
    • (2015) Development , vol.142 , pp. 3113-3125
    • Huch, M.1    Koo, B.-K.2
  • 36
    • 84880249396 scopus 로고    scopus 로고
    • Lgr5(+) liver stem cells, hepatic organoids and regenerative medicine
    • Huch, M., Boj, S. F. and Clevers, H. (2013a). Lgr5(+) liver stem cells, hepatic organoids and regenerative medicine. Regen. Med. 8, 385-387.
    • (2013) Regen. Med , vol.8 , pp. 385-387
    • Huch, M.1    Boj, S.F.2    Clevers, H.3
  • 42
    • 84879794922 scopus 로고    scopus 로고
    • Renal involvement and the role of Notch signalling in Alagille syndrome
    • Kamath, B. M., Spinner, N. B. and Rosenblum, N. D. (2013). Renal involvement and the role of Notch signalling in Alagille syndrome. Nat. Rev. Nephrol. 9, 409-418.
    • (2013) Nat. Rev. Nephrol , vol.9 , pp. 409-418
    • Kamath, B.M.1    Spinner, N.B.2    Rosenblum, N.D.3
  • 47
    • 0031848068 scopus 로고    scopus 로고
    • Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
    • Korinek, V., Barker, N., Moerer, P., van Donselaar, E., Huls, G., Peters, P. J. and Clevers, H. (1998). Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat. Genet. 19, 379-383.
    • (1998) Nat. Genet , vol.19 , pp. 379-383
    • Korinek, V.1    Barker, N.2    Moerer, P.3    Van Donselaar, E.4    Huls, G.5    Peters, P.J.6    Clevers, H.7
  • 48
    • 1342326910 scopus 로고    scopus 로고
    • Relevance of breast cancer cell lines as models for breast tumours: An update
    • Lacroix, M. and Leclercq, G. (2004). Relevance of breast cancer cell lines as models for breast tumours: an update. Breast Cancer Res. Treat. 83, 249-289.
    • (2004) Breast Cancer Res. Treat , vol.83 , pp. 249-289
    • Lacroix, M.1    Leclercq, G.2
  • 49
    • 84904396621 scopus 로고    scopus 로고
    • Organogenesis in a dish: Modeling development and disease using organoid technologies
    • Lancaster, M. A. and Knoblich, J. A. (2014). Organogenesis in a dish: modeling development and disease using organoid technologies. Science 345, 1247125.
    • (2014) Science , vol.345
    • Lancaster, M.A.1    Knoblich, J.A.2
  • 50
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer, C., Kinzler, K. W. and Vogelstein, B. (1998). Genetic instabilities in human cancers. Nature 396, 643-649.
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 51
    • 84957101587 scopus 로고    scopus 로고
    • A whole new ball game: Stem cell-derived epithelia in the study of host-microbe interactions
    • Leslie, J. L. and Young, V. B. (2016). A whole new ball game: stem cell-derived epithelia in the study of host-microbe interactions. Anaerobe 37, 25-28.
    • (2016) Anaerobe , vol.37 , pp. 25-28
    • Leslie, J.L.1    Young, V.B.2
  • 54
    • 0034576767 scopus 로고    scopus 로고
    • Human cancer cell lines: Fact and fantasy
    • Masters, J. R. W. (2000). Human cancer cell lines: fact and fantasy. Nat. Rev. 1, 233-236.
    • (2000) Nat. Rev , vol.1 , pp. 233-236
    • Masters, J.R.W.1
  • 55
    • 84924422753 scopus 로고    scopus 로고
    • Modeling colorectal cancer using CRISPRCas9-mediated engineering of human intestinal organoids
    • Matano, M., Date, S., Shimokawa, M., Takano, A., Fujii, M., Ohta, Y., Watanabe, T., Kanai, T. and Sato, T. (2015). Modeling colorectal cancer using CRISPRCas9-mediated engineering of human intestinal organoids. Nat. Med. 21, 256-262.
    • (2015) Nat. Med , vol.21 , pp. 256-262
    • Matano, M.1    Date, S.2    Shimokawa, M.3    Takano, A.4    Fujii, M.5    Ohta, Y.6    Watanabe, T.7    Kanai, T.8    Sato, T.9
  • 56
    • 84902603134 scopus 로고    scopus 로고
    • Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis
    • Moon, C., VanDussen, K. L., Miyoshi, H. and Stappenbeck, T. S. (2014). Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis. Mucosal. Immunol. 7, 818-828.
    • (2014) Mucosal. Immunol , vol.7 , pp. 818-828
    • Moon, C.1    Vandussen, K.L.2    Miyoshi, H.3    Stappenbeck, T.S.4
  • 57
    • 84959091265 scopus 로고    scopus 로고
    • Co-culture with intestinal epithelial organoids allows efficient expansion and motility analysis of intraepithelial lymphocytes
    • Nozaki, K., Mochizuki, W., Matsumoto, Y., Matsumoto, T., Fukuda, M., Mizutani, T., Watanabe, M. and Nakamura, T. (2016). Co-culture with intestinal epithelial organoids allows efficient expansion and motility analysis of intraepithelial lymphocytes. J. Gastroenterol. 51, 206-213.
    • (2016) J. Gastroenterol , vol.51 , pp. 206-213
    • Nozaki, K.1    Mochizuki, W.2    Matsumoto, Y.3    Matsumoto, T.4    Fukuda, M.5    Mizutani, T.6    Watanabe, M.7    Nakamura, T.8
  • 60
    • 85015296935 scopus 로고    scopus 로고
    • Using brain organoids to understand Zika virus-induced microcephaly
    • Qian, X., Nguyen, H. N., Jacob, F., Song, H. and Ming, G.-l. (2017). Using brain organoids to understand Zika virus-induced microcephaly. Development 144, 952-957.
    • (2017) Development , vol.144 , pp. 952-957
    • Qian, X.1    Nguyen, H.N.2    Jacob, F.3    Song, H.4    Ming, G.-L.5
  • 62
    • 0037460729 scopus 로고    scopus 로고
    • Cystic fibrosis
    • Ratjen, F. and Döring, G. (2003). Cystic fibrosis. Lancet 361, 681-689.
    • (2003) Lancet , vol.361 , pp. 681-689
    • Ratjen, F.1    Döring, G.2
  • 64
    • 84878013732 scopus 로고    scopus 로고
    • Life in the human stomach: Persistence strategies of the bacterial pathogen Helicobacter pylori
    • Salama, N. R., Hartung, M. L. and Müller, A. (2013). Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori. Nat. Rev. Microbiol. 11, 385-399.
    • (2013) Nat. Rev. Microbiol , vol.11 , pp. 385-399
    • Salama, N.R.1    Hartung, M.L.2    Müller, A.3
  • 70
    • 20744450475 scopus 로고    scopus 로고
    • Alpha1-antitrypsin deficiency
    • Stoller, J. K. and Aboussouan, L. S. (2005). Alpha1-antitrypsin deficiency. Lancet 365, 2225-2236.
    • (2005) Lancet , vol.365 , pp. 2225-2236
    • Stoller, J.K.1    Aboussouan, L.S.2
  • 79
    • 84922753974 scopus 로고    scopus 로고
    • A small intestinal organoid model of non-invasive enteric pathogen-epithelial cell interactions
    • Wilson, S. S., Tocchi, A., Holly, M. K., Parks, W. C. and Smith, J. G. (2015). A small intestinal organoid model of non-invasive enteric pathogen-epithelial cell interactions. Mucosal Immunol. 8, 352-361.
    • (2015) Mucosal Immunol , vol.8 , pp. 352-361
    • Wilson, S.S.1    Tocchi, A.2    Holly, M.K.3    Parks, W.C.4    Smith, J.G.5
  • 80
    • 84894623720 scopus 로고    scopus 로고
    • Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny
    • Yin, X., Farin, H. F., van Es, J. H., Clevers, H., Langer, R. and Karp, J. M. (2014). Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny. Nat. Methods 11, 106-112.
    • (2014) Nat. Methods , vol.11 , pp. 106-112
    • Yin, X.1    Farin, H.F.2    Van Es, J.H.3    Clevers, H.4    Langer, R.5    Karp, J.M.6
  • 83
    • 85009424076 scopus 로고    scopus 로고
    • Salmonella-infected crypt-derived intestinal organoid culture system for host-bacterial interactions
    • Zhang, Y.-G., Wu, S., Xia, Y. and Sun, J. (2014). Salmonella-infected crypt-derived intestinal organoid culture system for host-bacterial interactions. Physiol. Rep. 2, e12147.
    • (2014) Physiol. Rep , vol.2
    • Zhang, Y.-G.1    Wu, S.2    Xia, Y.3    Sun, J.4
  • 85
    • 84964031111 scopus 로고    scopus 로고
    • Analysis of immune cells from human mammary ductal epithelial organoids reveals vdelta2+ T cells that efficiently target breast carcinoma cells in the presence of bisphosphonate
    • Phila
    • Zumwalde, N. A., Haag, J. D., Sharma, D., Mirrielees, J. A., Wilke, L. G., Gould, M. N. and Gumperz, J. E. (2016). Analysis of immune cells from human mammary ductal epithelial organoids reveals vdelta2+ T cells that efficiently target breast carcinoma cells in the presence of bisphosphonate. Cancer Prev. Res. (Phila.) 9, 305-316.
    • (2016) Cancer Prev. Res , vol.9 , pp. 305-316
    • Zumwalde, N.A.1    Haag, J.D.2    Sharma, D.3    Mirrielees, J.A.4    Wilke, L.G.5    Gould, M.N.6    Gumperz, J.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.