메뉴 건너뛰기




Volumn 13, Issue 7, 2001, Pages 763-770

Peptide growth factors in the intestine

Author keywords

Cytokine; Epithelium; Growth factor; Intestine; Keywords; Regulatory peptide

Indexed keywords

COLONY STIMULATING FACTOR; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; SCATTER FACTOR; SOMATOMEDIN; TRANSFORMING GROWTH FACTOR BETA; TREFOIL PEPTIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0034959462     PISSN: 0954691X     EISSN: 14735687     Source Type: Journal    
DOI: 10.1097/00042737-200107000-00002     Document Type: Review
Times cited : (152)

References (117)
  • 1
    • 0024516924 scopus 로고
    • Peptide regulatory factors: multifunctional mediators of cellular growth and differentiation.
    • Green AR. Peptide regulatory factors: multifunctional mediators of cellular growth and differentiation. Lancet 1989; i: 705-707.
    • (1989) Lancet , vol.i , pp. 705
    • Green, A.R.1
  • 2
    • 0026675933 scopus 로고
    • Autocrine secretion - 10 years later.
    • Sporn MB, Roberts AB. Autocrine secretion - 10 years later. Ann Intern Med 1992; 117: 408-414. Excellent overview about the basic characteristics of regulatory peptides and their mechanisms to modulate various cell functions.
    • (1992) Ann Intern Med , vol.117 , pp. 408
    • •Sporn, M.B.1    Roberts, A.B.2
  • 3
    • 0025719982 scopus 로고
    • Cytokines in context.
    • Nathan C, Sporn M. Cytokines in context. J Cell Biol 1991; 113: 981-986. Good description and definition of the cytokine network. This review illustrates the complex interactions of cytokines within a complex network of regulatory peptides, extracellular matrix factors, cell-cell contacts, and other modulatory factors.
    • (1991) J Cell Biol , vol.113 , pp. 981
    • •Nathan, C.1    Sporn, M.2
  • 4
    • 0026445528 scopus 로고
    • Transforming growth factor-β: recent progress and new challenges.
    • Sporn MB, Roberts AB. Transforming growth factor-β: recent progress and new challenges. J Cell Biol 1992; 119: 1017-1021.
    • (1992) J Cell Biol , vol.119 , pp. 1017
    • Sporn, M.B.1    Roberts, A.B.2
  • 5
    • 85026156164 scopus 로고    scopus 로고
    • ••Sporn MB, Roberts AB. Peptide Growth Factors and Their Receptors I and II. New York: Springer-Verlag; 1991. Although a little outdated, this book provides an excellent overview of regulatory peptides, with extensive descriptions of all relevant growth factor families and their most important representatives. A must for anybody who is interested in the numerous, and constantly increasing number of cytokines and their biological effects.
    • ••Sporn MB, Roberts AB. Peptide Growth Factors and Their Receptors I and II. New York: Springer-Verlag; 1991. Although a little outdated, this book provides an excellent overview of regulatory peptides, with extensive descriptions of all relevant growth factor families and their most important representatives. A must for anybody who is interested in the numerous, and constantly increasing number of cytokines and their biological effects.
  • 6
    • 85026182931 scopus 로고    scopus 로고
    • Babyatsky MW, Podolsky DK. Growth and differentiation in the GI tract. In: Textbook of Gastroenterology. Yamada T, Alpers DH, Owyang C, Powell DW, Silverstein FE (editors). New York: Lippincott; 1991. pp. 475-501.
    • Babyatsky MW, Podolsky DK. Growth and differentiation in the GI tract. In: Textbook of Gastroenterology. Yamada T, Alpers DH, Owyang C, Powell DW, Silverstein FE (editors). New York: Lippincott; 1991. pp. 475-501.
  • 7
    • 85026183400 scopus 로고    scopus 로고
    • Dignass AU, Podolsky DK. Growth factors in inflammatory bowel disease. In: Cytokines in Inflammatory Bowel Disease. Fiocchi C (editor). Austin: R.G. Landes; 1996. pp. 137-155.
    • Dignass AU, Podolsky DK. Growth factors in inflammatory bowel disease. In: Cytokines in Inflammatory Bowel Disease. Fiocchi C (editor). Austin: R.G. Landes; 1996. pp. 137-155.
  • 8
    • 0034018106 scopus 로고    scopus 로고
    • Mechanisms of regulatory peptide action in the gastrointestinal tract: trefoil peptides.
    • Podolsky DK. Mechanisms of regulatory peptide action in the gastrointestinal tract: trefoil peptides. J Gastroenterol 2000; 35 (suppl 12): 69-74. Excellent overview that summarizes the current knowledge on TFFs and their modulatory effects within the gastrointestinal tract.
    • (2000) J Gastroenterol , vol.35 , pp. 69
    • ••Podolsky, D.K.1
  • 9
    • 0033072530 scopus 로고    scopus 로고
    • Growth factors in inflammatory bowel disease.
    • Beck PL, Podolsky DK. Growth factors in inflammatory bowel disease. Inflamm Bowel Dis 1999; 5: 44-60. Extensive and systematic review of the role of growth factors in inflammatory bowel disease.
    • (1999) Inflamm Bowel Dis , vol.5 , pp. 44
    • •Beck, P.L.1    Podolsky, D.K.2
  • 10
    • 0033558498 scopus 로고    scopus 로고
    • Gastrointestinal mucosal regeneration: role of growth factors.
    • Jones MK, Tomikawa M, Mohajer B, Tarnawski AS. Gastrointestinal mucosal regeneration: role of growth factors. Front Biosci 1999; 4: D303-309. Review that summarizes the effects of growth factors on gastrointestinal repair mechanisms in a systematic fashion.
    • (1999) Front Biosci , vol.4
    • •Jones, M.K.1    Tomikawa, M.2    Mohajer, B.3    Tarnawski, A.S.4
  • 11
    • 0032188840 scopus 로고    scopus 로고
    • Growth factors and the gastrointestinal tract.
    • Murphy MS. Growth factors and the gastrointestinal tract. Nutrition 1998; 14: 771-774.
    • (1998) Nutrition , vol.14 , pp. 771
    • Murphy, M.S.1
  • 12
    • 0028281588 scopus 로고
    • The role of growth factors in gastrointestinal cell proliferation.
    • Alison MR, Sarraf CE. The role of growth factors in gastrointestinal cell proliferation. Cell Biol Int 1994; 18: 1-10.
    • (1994) Cell Biol Int , vol.18 , pp. 1
    • Alison, M.R.1    Sarraf, C.E.2
  • 14
    • 0031045974 scopus 로고    scopus 로고
    • Healing the epithelium: solving the problem from two sides.
    • Podolsky DK. Healing the epithelium: solving the problem from two sides. J Gastroenterol 1997; 32: 122-126.
    • (1997) J Gastroenterol , vol.32 , pp. 122
    • Podolsky, D.K.1
  • 15
    • 0030852014 scopus 로고    scopus 로고
    • Epithelial migration in the colon: filling in the gaps.
    • Wilson AJ, Gibson PR. Epithelial migration in the colon: filling in the gaps. Clin Sci (Colch) 1997; 93: 97-108. Excellent and systematic overview of the current status of epithelial restitution (migration), with a special focus on the modulation of epithelial migration by growth factors.
    • (1997) Clin Sci Colch , vol.93 , pp. 97
    • ••Wilson, A.J.1    Gibson, P.R.2
  • 16
    • 0031914778 scopus 로고    scopus 로고
    • Cytokines in inflammatory bowel disease.
    • Rogler G, Andus T. Cytokines in inflammatory bowel disease. World J Surg 1998; 22: 382-389.
    • (1998) World J Surg , vol.22 , pp. 382
    • Rogler, G.1    Andus, T.2
  • 17
    • 85026162068 scopus 로고    scopus 로고
    • •Carpenter G, Wahl MI. The epidermal growth factor family. In: Peptides, Growth Factors and their Receptors I. Sporn MB, Roberts AB (editors). New York: Springer-Verlag; 1991. pp. 69-171. Although a little outdated, this review provides important information about EGF family peptides and may serve as a valuable source to anyone who wants to get an overview about the structural and functional properties of EGF family peptides.
    • •Carpenter G, Wahl MI. The epidermal growth factor family. In: Peptides, Growth Factors and their Receptors I. Sporn MB, Roberts AB (editors). New York: Springer-Verlag; 1991. pp. 69-171. Although a little outdated, this review provides important information about EGF family peptides and may serve as a valuable source to anyone who wants to get an overview about the structural and functional properties of EGF family peptides.
  • 18
    • 0025823006 scopus 로고
    • Radioautographic localization of epidermal growth factor receptors in human fetal gut.
    • Menard D, Pothier P. Radioautographic localization of epidermal growth factor receptors in human fetal gut. Gastroenterology 1991; 101: 640-649.
    • (1991) Gastroenterology , vol.101 , pp. 640
    • Menard, D.1    Pothier, P.2
  • 19
    • 0024595303 scopus 로고
    • Differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells.
    • Koyama SY, Podolsky DK. Differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells. J Clin Invest 1989; 83: 1768-1773.
    • (1989) J Clin Invest , vol.83 , pp. 1768
    • Koyama, S.Y.1    Podolsky, D.K.2
  • 20
    • 0030897178 scopus 로고    scopus 로고
    • Differential activation of total and EGF receptor (EGF-R) tyrosine kinase (tyr-k) in the rectal mucosa in patients with adenomatous polyps, ulcerative colitis and colon cancer.
    • Malecka-Panas E, Kordek R, Biernat W, Tureaud J, Liberski PP, Majumdar AP. Differential activation of total and EGF receptor (EGF-R) tyrosine kinase (tyr-k) in the rectal mucosa in patients with adenomatous polyps, ulcerative colitis and colon cancer. Hepatogastroenterology 1997; 44: 435-440.
    • (1997) Hepatogastroenterology , vol.44 , pp. 435
    • Malecka-Panas, E.1    Kordek, R.2    Biernat, W.3    Tureaud, J.4    Liberski, P.P.5    Majumdar, A.P.6
  • 21
    • 0032783554 scopus 로고    scopus 로고
    • Immunolocalization of transforming growth factor-alpha and epidermal growth factor receptor in the rat gastroduodenal area.
    • Montaner B, Asbert M, Perez-Tomas R. Immunolocalization of transforming growth factor-alpha and epidermal growth factor receptor in the rat gastroduodenal area. Dig Dis Sci 1999; 44: 1408-1416.
    • (1999) Dig Dis Sci , vol.44 , pp. 1408
    • Montaner, B.1    Asbert, M.2    Perez-Tomas, R.3
  • 22
    • 0032429008 scopus 로고    scopus 로고
    • The role of epidermal growth factor (EGF) and its receptor in mucosal protection, adaptation to injury, and ulcer healing: involvement of EGF-R signal transduction pathways.
    • Tarnawski AS, Jones MK. The role of epidermal growth factor (EGF) and its receptor in mucosal protection, adaptation to injury, and ulcer healing: involvement of EGF-R signal transduction pathways. J Clin Gastroenterol 1998; 27 (suppl 1): 12-20.
    • (1998) J Clin Gastroenterol , vol.27 , pp. 12
    • Tarnawski, A.S.1    Jones, M.K.2
  • 23
    • 0033194417 scopus 로고    scopus 로고
    • Epidermal growth factor, epidermal growth factor receptors, intestinal growth, and adaptation.
    • Wong WM, Wright NA. Epidermal growth factor, epidermal growth factor receptors, intestinal growth, and adaptation. J Parenter Enteral Nutr 1999; 23: S83-88.
    • (1999) J Parenter Enteral Nutr , vol.23
    • Wong, W.M.1    Wright, N.A.2
  • 24
    • 0024386092 scopus 로고
    • Distribution and release of epidermal growth factor in man.
    • Konturek JW, Bielanski W, Konturek SJ. Distribution and release of epidermal growth factor in man. Gut 1989; 30: 1194-1200.
    • (1989) Gut , vol.30 , pp. 1194
    • Konturek, J.W.1    Bielanski, W.2    Konturek, S.J.3
  • 25
    • 0025858507 scopus 로고
    • Trophic action of epidermal growth factor on human duodenal mucosa cultured in vitro.
    • Challacombe DN, Wheeler EE. Trophic action of epidermal growth factor on human duodenal mucosa cultured in vitro. Gut 1991; 32: 991-993.
    • (1991) Gut , vol.32 , pp. 991
    • Challacombe, D.N.1    Wheeler, E.E.2
  • 26
    • 0025969997 scopus 로고
    • The effects of intracolonic EGF on mucosal growth and experimental carcinogenesis.
    • Reeves JR, Richards RC, Cooke T. The effects of intracolonic EGF on mucosal growth and experimental carcinogenesis. Br J Cancer 1991; 63: 223-226.
    • (1991) Br J Cancer , vol.63 , pp. 223
    • Reeves, J.R.1    Richards, R.C.2    Cooke, T.3
  • 27
    • 0023883404 scopus 로고
    • Specific receptors for epidermal growth factor in rat intestinal microvillus membranes.
    • Thompson JF. Specific receptors for epidermal growth factor in rat intestinal microvillus membranes. Am J Physiol 1988; 254: G429-435.
    • (1988) Am J Physiol , vol.254
    • Thompson, J.F.1
  • 28
    • 0024561129 scopus 로고
    • Epidermal growth factor receptor of the intestinal enterocyte localization to the laterobasal but not brush border membrane.
    • Scheving LA, Shiurba RA, Nguyen TD. Epidermal growth factor receptor of the intestinal enterocyte localization to the laterobasal but not brush border membrane. J Biol Chem 1989; 264: 1735-1741.
    • (1989) J Biol Chem , vol.264 , pp. 1735
    • Scheving, L.A.1    Shiurba, R.A.2    Nguyen, T.D.3
  • 29
    • 0023115518 scopus 로고
    • Effects of growth factors on an intestinal epithelial cell line: transforming growth factor beta inhibits proliferation and stimulates differentiation.
    • Kurokowa M, Lynch K, Podolsky DK. Effects of growth factors on an intestinal epithelial cell line: transforming growth factor beta inhibits proliferation and stimulates differentiation. Biochem Biophys Res Commun 1987; 142: 775-782.
    • (1987) Biochem Biophys Res Commun , vol.142 , pp. 775
    • Kurokowa, M.1    Lynch, K.2    Podolsky, D.K.3
  • 30
    • 0025321157 scopus 로고
    • Epidermal growth factor.
    • Carpenter G, Cohen S. Epidermal growth factor. J Biol Chem 1990; 265: 7709-7712.
    • (1990) J Biol Chem , vol.265 , pp. 7709
    • Carpenter, G.1    Cohen, S.2
  • 31
    • 0023120988 scopus 로고
    • Effect of epidermal growth on polyamine-synthesizing enzymes in rat enterocytes.
    • Fitzpatrick LR, Wang P, Johnson LR. Effect of epidermal growth on polyamine-synthesizing enzymes in rat enterocytes. Am J Physiol 1987; 252: G209-214.
    • (1987) Am J Physiol , vol.252
    • Fitzpatrick, L.R.1    Wang, P.2    Johnson, L.R.3
  • 32
    • 0025741817 scopus 로고
    • Epidermal growth factor upregulates intestinal electrolyte and nutrient transport.
    • Opleta-Madsen K, Hardin J, Gall DG. Epidermal growth factor upregulates intestinal electrolyte and nutrient transport. Am J Physiol 1991; 260: G807-814.
    • (1991) Am J Physiol , vol.260
    • Opleta-Madsen, K.1    Hardin, J.2    Gall, D.G.3
  • 33
    • 0029944033 scopus 로고    scopus 로고
    • Epidermal growth factor promotes rapid response to epithelial injury in rabbit duodenum in vitro.
    • Riegler M, Sedivy R, Sogukoglu T, Cosentini E, Bischof G, Teleky B. et al. Epidermal growth factor promotes rapid response to epithelial injury in rabbit duodenum in vitro. Gastroenterology 1996; 111: 28-36.
    • (1996) Gastroenterology , vol.111 , pp. 28
    • Riegler, M.1    Sedivy, R.2    Sogukoglu, T.3    Cosentini, E.4    Bischof, G.5    Teleky, B.6
  • 34
    • 0027436376 scopus 로고
    • Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor beta.
    • Dignass AU, Podolsky DK. Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor beta. Gastroenterology 1993; 105: 1323-1332. Demonstrates that several cytokines that are expressed within the intestinal mucosa enhance epithelial restitution, the initial step of epithelial repair following superficial injury, through a TGF-β-dependent mechanism, highlighting the central role of TGF-β in the maintenance of intestinal epithelial homeostasis.
    • (1993) Gastroenterology , vol.105 , pp. 1323
    • •Dignass, A.U.1    Podolsky, D.K.2
  • 35
    • 0024553106 scopus 로고
    • Expression of transforming growth factor α messenger RNA in the normal and neoplastic gastro-intestinal tract.
    • Malden LT, Novack U, Burgess AW. Expression of transforming growth factor α messenger RNA in the normal and neoplastic gastro-intestinal tract. Int J Cancer 1989; 43: 380-384.
    • (1989) Int J Cancer , vol.43 , pp. 380
    • Malden, L.T.1    Novack, U.2    Burgess, A.W.3
  • 36
    • 0026517131 scopus 로고
    • Immunoreactivity of transforming growth factor α in the normal adult gastrointestinal tract.
    • Thomas DM, Nasim MM, Gullick WJ. Immunoreactivity of transforming growth factor α in the normal adult gastrointestinal tract. Gut 1992; 33: 628-631.
    • (1992) Gut , vol.33 , pp. 628
    • Thomas, D.M.1    Nasim, M.M.2    Gullick, W.J.3
  • 37
    • 0032780384 scopus 로고    scopus 로고
    • Expression of transforming growth factor-alpha and epidermal growth factor receptor in gastrointestinal stromal tumours.
    • Cai YC, Jiang Z, Vittimberga F, Xu X, Savas L, Woda B. et al. Expression of transforming growth factor-alpha and epidermal growth factor receptor in gastrointestinal stromal tumours. Virchows Arch 1999; 435: 112-115.
    • (1999) Virchows Arch , vol.435 , pp. 112
    • Cai, Y.C.1    Jiang, Z.2    Vittimberga, F.3    Xu, X.4    Savas, L.5    Woda, B.6
  • 38
    • 0029913624 scopus 로고    scopus 로고
    • Expression of transforming growth factor α and β in colonic mucosa in inflammatory bowel disease.
    • Babyatsky MW, Rossiter G, Podolsky DK. Expression of transforming growth factor α and β in colonic mucosa in inflammatory bowel disease. Gastroenterology 1996; 110: 975-984. Demonstrates increased expression of TGF-β in areas with active inflammation in both ulcerative colitis and Crohn's disease patients, and enhanced expression of TGF-α in quiescent mucosa of ulcerative colitis patients with long-standing ulcerative colitis, indicating that these peptides may play an important role in intestinal repair and development of neoplasia in patients with inflammatory bowel disease.
    • (1996) Gastroenterology , vol.110 , pp. 975
    • •Babyatsky, M.W.1    Rossiter, G.2    Podolsky, D.K.3
  • 39
  • 40
    • 0026720594 scopus 로고
    • Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon.
    • Johnson GR, Saeki T, Gordon AW, Shoyab M, Salomon DS, Stromberg K. Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon. J Cell Biol 1992; 118: 741-751.
    • (1992) J Cell Biol , vol.118 , pp. 741
    • Johnson, G.R.1    Saeki, T.2    Gordon, A.W.3    Shoyab, M.4    Salomon, D.S.5    Stromberg, K.6
  • 41
    • 0026725097 scopus 로고
    • Differential immunohistochemical detection of amphiregulin and cripto in human normal colon and colorectal tumors.
    • Saeki T, Stromberg K, Qi CF, Gullick WJ, Tahara E, Normanno N. et al. Differential immunohistochemical detection of amphiregulin and cripto in human normal colon and colorectal tumors. Cancer Res 1992; 52: 3467-3473.
    • (1992) Cancer Res , vol.52 , pp. 3467
    • Saeki, T.1    Stromberg, K.2    Qi, C.F.3    Gullick, W.J.4    Tahara, E.5    Normanno, N.6
  • 42
    • 0025858250 scopus 로고
    • Differential expression of epidermal growth factor-related proteins in human colorectal tumors.
    • Ciardiello F, Kim N, Saeki T. Differential expression of epidermal growth factor-related proteins in human colorectal tumors. Proc Nat Acad Sci USA 1991; 88: 7792-7796.
    • (1991) Proc Nat Acad Sci USA , vol.88 , pp. 7792
    • Ciardiello, F.1    Kim, N.2    Saeki, T.3
  • 43
    • 0025222517 scopus 로고
    • The transforming growth factor β family.
    • Massague J. The transforming growth factor β family. Annu Rev Cell Biol 1990; 6: 597-641. Although a little outdated, this review provides important information about TGF-β family peptides and may serve as a valuable source to anyone who wants to get an overview of the structural and functional properties of TGF-β family peptides.
    • (1990) Annu Rev Cell Biol , vol.6 , pp. 597
    • ••Massague, J.1
  • 44
    • 0026750213 scopus 로고
    • Receptors for the TGF-β family.
    • Massague J. Receptors for the TGF-β family. Cell 1992; 69: 1067-1070. Although a little outdated, this review provides extensive information about TGF-β family receptors and may serve as a valuable source to anyone who wants to get an overview of TGF-β family peptide signalling.
    • (1992) Cell , vol.69 , pp. 1067
    • ••Massague, J.1
  • 45
    • 0025215307 scopus 로고
    • Mechanism of activation of latent recombinant transforming growth factor β1 by plasmin.
    • Lyons RM, Gentry LE, Purchio AF. Mechanism of activation of latent recombinant transforming growth factor β1 by plasmin. J Cell Biol 1990; 110: 1361-1367.
    • (1990) J Cell Biol , vol.110 , pp. 1361
    • Lyons, R.M.1    Gentry, L.E.2    Purchio, A.F.3
  • 46
    • 0027250810 scopus 로고
    • Inactivation of the type II receptor reveals two receptor pathways for the diverse TGFβ activities.
    • Chen R-H, Ebner R, Derynck R. Inactivation of the type II receptor reveals two receptor pathways for the diverse TGFβ activities. Science 1993; 260: 1335-1338.
    • (1993) Science , vol.260 , pp. 1335
    • Chen, R.-H.1    Ebner, R.2    Derynck, R.3
  • 47
    • 0025987832 scopus 로고
    • Structure and expression of the membrane proteoglycan betaglycan, a component of the TGFβ receptor system.
    • Lopez-Casillas F, Cheifetz S, Doody J. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGFβ receptor system. Cell 1991; 67: 785-795.
    • (1991) Cell , vol.67 , pp. 785
    • Lopez-Casillas, F.1    Cheifetz, S.2    Doody, J.3
  • 48
    • 0031685620 scopus 로고    scopus 로고
    • TFG-beta signal transduction.
    • Massague J. TFG-beta signal transduction. Annu Rev Biochem 1998; 67: 753-791. Up-to-date summary about TGF-β signalling mechanisms and characterization of signal transduction pathways.
    • (1998) Annu Rev Biochem , vol.67 , pp. 753
    • ••Massague, J.1
  • 49
    • 0031911356 scopus 로고    scopus 로고
    • SMADs: mediators and regulators of TGF-beta signaling.
    • Kretzschmar M, Massague J. SMADs: mediators and regulators of TGF-beta signaling. Curr Opin Genet Dev 1998; 8: 103-111. Excellent summary of the rapidly expanding understanding of the major regulatory network of SMAD proteins and their role in TGF-β signalling.
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 103
    • ••Kretzschmar, M.1    Massague, J.2
  • 51
    • 0030761239 scopus 로고    scopus 로고
    • Transforming growth factor (TGF-beta)-specific signaling by chimeric TGF-beta type II receptor with intracellular domain of activin type IIB receptor.
    • Persson U, Souchelnytskyi S, Franzen P, Miyazono K, ten Dijke P, Heldin CH. Transforming growth factor (TGF-beta)-specific signaling by chimeric TGF-beta type II receptor with intracellular domain of activin type IIB receptor. J Biol Chem 1997; 272: 21 187-21 194.
    • (1997) J Biol Chem , vol.272
    • Persson, U.1    Souchelnytskyi, S.2    Franzen, P.3    Miyazono, K.4    ten Dijke, P.5    Heldin, C.H.6
  • 52
    • 0027301264 scopus 로고
    • Localizations of TGFβ isoforms in the normal small intestine and colon.
    • Barnard JA, Warwick GJ, Gold L. Localizations of TGFβ isoforms in the normal small intestine and colon. Gastroenterology 1993; 105: 67-73.
    • (1993) Gastroenterology , vol.105 , pp. 67
    • Barnard, J.A.1    Warwick, G.J.2    Gold, L.3
  • 53
    • 0029970132 scopus 로고    scopus 로고
    • Acute epithelial injury in the rat small intestine in vivo is associated with expanded expression of transforming growth factor alpha and beta.
    • Dignass AU, Stow JL, Babyatsky MW. Acute epithelial injury in the rat small intestine in vivo is associated with expanded expression of transforming growth factor alpha and beta. Gut 1996; 38: 687-693.
    • (1996) Gut , vol.38 , pp. 687
    • Dignass, A.U.1    Stow, J.L.2    Babyatsky, M.W.3
  • 54
    • 0026559398 scopus 로고
    • Transforming growth factor beta (TGFβ) in inflammation: a cause and a cure.
    • Wahl SM. Transforming growth factor beta (TGFβ) in inflammation: a cause and a cure. J Clin Immunol 1992; 12: 61-74. Good review about the potential role of TGF-β in inflammation, which highlights potential beneficial and deleterious effects of TGF-β.
    • (1992) J Clin Immunol , vol.12 , pp. 61
    • •Wahl, S.M.1
  • 55
    • 0026778310 scopus 로고
    • Transforming growth factor β1 in disease: the dark side of tissue repair.
    • Border WA, Ruoslathi E. Transforming growth factor β1 in disease: the dark side of tissue repair. J Clin Invest 1992; 90: 1-7.
    • (1992) J Clin Invest , vol.90 , pp. 1
    • Border, W.A.1    Ruoslathi, E.2
  • 56
    • 0343145719 scopus 로고    scopus 로고
    • Activin A: a novel player and inflammatory marker in inflammatory bowel disease?
    • Hubner G, Brauchle M, Gregor M, Werner S. Activin A: a novel player and inflammatory marker in inflammatory bowel disease? Lab Invest 1997; 77: 311-318.
    • (1997) Lab Invest , vol.77 , pp. 311
    • Hubner, G.1    Brauchle, M.2    Gregor, M.3    Werner, S.4
  • 58
    • 0033955251 scopus 로고    scopus 로고
    • Gene expression of activin, activin receptors, and follistatin in intestinal epithelial cells.
    • Sonoyama K, Rutatip S, Kasai T. Gene expression of activin, activin receptors, and follistatin in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 2000; 278: G89-97.
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.278
    • Sonoyama, K.1    Rutatip, S.2    Kasai, T.3
  • 60
    • 0031884321 scopus 로고    scopus 로고
    • Insulin-like growth factor-I partially attenuates colonic damage in rats with experimental colitis induced by oral dextran sulphate sodium.
    • Howarth GS, Xian CJ, Read LC. Insulin-like growth factor-I partially attenuates colonic damage in rats with experimental colitis induced by oral dextran sulphate sodium. Scand J Gastroenterol 1998; 33: 180-190. Interesting study that provides evidence that IGF I plays a potential role in modulating intestinal injury in vivo.
    • (1998) Scand J Gastroenterol , vol.33 , pp. 180
    • •Howarth, G.S.1    Xian, C.J.2    Read, L.C.3
  • 61
    • 85026162623 scopus 로고    scopus 로고
    • ••Rechler MM, Nissley SP. Insulin-like growth factors. In: Peptide Growth Factors and Their Receptors I. Sporn MB, Roberts AB (editors). New York: Springer-Verlag; 1991. pp. 263-367. Although a little outdated, this review provides extensive information about IGF family peptides and may serve as a valuable source to anyone who wants to get an overview of the structural and functional properties of IGF family peptides.
    • ••Rechler MM, Nissley SP. Insulin-like growth factors. In: Peptide Growth Factors and Their Receptors I. Sporn MB, Roberts AB (editors). New York: Springer-Verlag; 1991. pp. 263-367. Although a little outdated, this review provides extensive information about IGF family peptides and may serve as a valuable source to anyone who wants to get an overview of the structural and functional properties of IGF family peptides.
  • 62
    • 0025310235 scopus 로고
    • Autocrine regulation of human tumor cell proliferation by insulin-like growth factor II: an in vitro model.
    • Thompson MA, Cox AJ, Whitehead RH, Jonas HA. Autocrine regulation of human tumor cell proliferation by insulin-like growth factor II: an in vitro model. Endocrinology 1990; 126: 3033-3042.
    • (1990) Endocrinology , vol.126 , pp. 3033
    • Thompson, M.A.1    Cox, A.J.2    Whitehead, R.H.3    Jonas, H.A.4
  • 63
    • 0025040263 scopus 로고
    • Insulin-like growth factor and the developing and mature rat small intestine: receptors and biological actions.
    • Young GP, Taranto TM, Jonas HA. Insulin-like growth factor and the developing and mature rat small intestine: receptors and biological actions. Digestion 1990; 46: 240-252.
    • (1990) Digestion , vol.46 , pp. 240
    • Young, G.P.1    Taranto, T.M.2    Jonas, H.A.3
  • 64
    • 0029928613 scopus 로고    scopus 로고
    • Insulin-like growth factors and inflammatory bowel disease.
    • Lund PK, Zimmermann EM. Insulin-like growth factors and inflammatory bowel disease. Baillieres Clin Gastroenterol 1996; 10: 83-96. Summarizes the important role of IGF peptides in inflammatory bowel diseases.
    • (1996) Baillieres Clin Gastroenterol , vol.10 , pp. 83
    • •Lund, P.K.1    Zimmermann, E.M.2
  • 65
    • 0027216271 scopus 로고
    • Insulin-like growth factor I and interleukin 1β messenger RNA in a rat model of granulomatous enterocolitis and hepatitis.
    • Zimmermann EM, Sartor RB, McCall RD, Pardo M, Bender D, Lund PK. Insulin-like growth factor I and interleukin 1β messenger RNA in a rat model of granulomatous enterocolitis and hepatitis. Gastroenterology 1993; 105: 399-409.
    • (1993) Gastroenterology , vol.105 , pp. 399
    • Zimmermann, E.M.1    Sartor, R.B.2    McCall, R.D.3    Pardo, M.4    Bender, D.5    Lund, P.K.6
  • 66
    • 85026157156 scopus 로고    scopus 로고
    • ••Baird A, Böhlen P. Fibroblast growth factors. In: Peptide Growth Factors and Their Receptors I. Sporn MB, Roberts AB (editors). New York: Springer-Verlag; 1991. pp. 369-418. Although a little outdated, this review provides an extensive overview of FGF peptides and may serve as a valuable source to anyone who wants to get an overview of the structural and functional properties of FGF peptides.
    • ••Baird A, Böhlen P. Fibroblast growth factors. In: Peptide Growth Factors and Their Receptors I. Sporn MB, Roberts AB (editors). New York: Springer-Verlag; 1991. pp. 369-418. Although a little outdated, this review provides an extensive overview of FGF peptides and may serve as a valuable source to anyone who wants to get an overview of the structural and functional properties of FGF peptides.
  • 67
    • 0028285145 scopus 로고
    • Immunohistochemical localization of basic fibroblast growth factor in the normal adult gastrointestinal tract.
    • Ernst H, Muller M, Paulus A, Hahn EG, Ell C. Immunohistochemical localization of basic fibroblast growth factor in the normal adult gastrointestinal tract. Eur J Gastroenterol Hepatol 1994; 6: 559-564.
    • (1994) Eur J Gastroenterol Hepatol , vol.6 , pp. 559
    • Ernst, H.1    Muller, M.2    Paulus, A.3    Hahn, E.G.4    Ell, C.5
  • 68
    • 0026595569 scopus 로고
    • Identification of basic growth factor sensitivity and receptor and ligand expression in human colon tumor cell lines.
    • New BA, Yeoman LC. Identification of basic growth factor sensitivity and receptor and ligand expression in human colon tumor cell lines. J Cell Physiol 1992; 150: 320-326.
    • (1992) J Cell Physiol , vol.150 , pp. 320
    • New, B.A.1    Yeoman, L.C.2
  • 69
    • 0026327501 scopus 로고
    • The major colonic cell mitogen extractable from colonic mucosa is an N-terminally extended form of basic fibroblast growth factor.
    • Nice EC, Fabri L, Whitehead RH, James R, Simpson RJ, Burgess AW. The major colonic cell mitogen extractable from colonic mucosa is an N-terminally extended form of basic fibroblast growth factor. J Biol Chem 1991; 22: 14 425-14 430.
    • (1991) J Biol Chem , vol.22
    • Nice, E.C.1    Fabri, L.2    Whitehead, R.H.3    James, R.4    Simpson, R.J.5    Burgess, A.W.6
  • 70
    • 0027300806 scopus 로고
    • Immunocytochemical localization of basic fibroblast growth factor in carcinomas and inflammatory lesions of the human digestive tract.
    • Ohtani H, Nakamura S, Watanabe Y, Mizoi T, Saku T, Nagura H. Immunocytochemical localization of basic fibroblast growth factor in carcinomas and inflammatory lesions of the human digestive tract. Lab Invest 1993; 68: 520-527.
    • (1993) Lab Invest , vol.68 , pp. 520
    • Ohtani, H.1    Nakamura, S.2    Watanabe, Y.3    Mizoi, T.4    Saku, T.5    Nagura, H.6
  • 72
    • 0031038857 scopus 로고    scopus 로고
    • Fibroblast growth factor 1 and fibroblast growth factor 2 immunoreactivity in gastrointestinal tumours.
    • El Hariry I, Pignatelli M, Lemoine N. Fibroblast growth factor 1 and fibroblast growth factor 2 immunoreactivity in gastrointestinal tumours. J Pathol 1997; 181: 39-45.
    • (1997) J Pathol , vol.181 , pp. 39
    • El Hariry, I.1    Pignatelli, M.2    Lemoine, N.3
  • 73
    • 0028231686 scopus 로고
    • Fibroblast growth factors modulate intestinal epithelial cell growth and migration.
    • Dignass AU, Tsunekawa S, Podolsky DK. Fibroblast growth factors modulate intestinal epithelial cell growth and migration. Gastroenterology 1994; 106: 1254-1262.
    • (1994) Gastroenterology , vol.106 , pp. 1254
    • Dignass, A.U.1    Tsunekawa, S.2    Podolsky, D.K.3
  • 74
    • 0028080029 scopus 로고
    • Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract.
    • Housley RM, Morris CF, Boyle W, Ring B, Biltz R, Tarpley JE. et al. Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract. J Clin Invest 1994; 94: 1764-1777.
    • (1994) J Clin Invest , vol.94 , pp. 1764
    • Housley, R.M.1    Morris, C.F.2    Boyle, W.3    Ring, B.4    Biltz, R.5    Tarpley, J.E.6
  • 75
    • 0029846763 scopus 로고    scopus 로고
    • Effects of growth factors and gut hormones on proliferation of primary cultured gastric mucous cells of guinea pig.
    • Matsuda K, Sakamoto C, Konda Y, Nakano O, Matozaki T, Nishisaki H. et al. Effects of growth factors and gut hormones on proliferation of primary cultured gastric mucous cells of guinea pig. J Gastroenterol 1996; 31: 498-504.
    • (1996) J Gastroenterol , vol.31 , pp. 498
    • Matsuda, K.1    Sakamoto, C.2    Konda, Y.3    Nakano, O.4    Matozaki, T.5    Nishisaki, H.6
  • 77
    • 0031702821 scopus 로고    scopus 로고
    • FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation.
    • Hu MC, Qiu WR, Wang YP, Hill D, Ring BD, Scully S. et al. FGF-18, a novel member of the fibroblast growth factor family, stimulates hepatic and intestinal proliferation. Mol Cell Biol 1998; 18: 6063-6074.
    • (1998) Mol Cell Biol , vol.18 , pp. 6063
    • Hu, M.C.1    Qiu, W.R.2    Wang, Y.P.3    Hill, D.4    Ring, B.D.5    Scully, S.6
  • 79
    • 0029929320 scopus 로고    scopus 로고
    • The trefoil peptide family.
    • Sands BE, Podolsky DK. The trefoil peptide family. Annu Rev Physiol 1996; 58: 253-273. Extensive overview of the structural, physicochemical and functional activities of TFF peptides and their expression in various tissues, including the gastrointestinal tract.
    • (1996) Annu Rev Physiol , vol.58 , pp. 253
    • ••Sands, B.E.1    Podolsky, D.K.2
  • 81
    • 0031449635 scopus 로고    scopus 로고
    • Trefoil peptides: from structure to function.
    • Thim L. Trefoil peptides: from structure to function. Cell Mol Life Sci 1997; 53: 888-903.
    • (1997) Cell Mol Life Sci , vol.53 , pp. 888
    • Thim, L.1
  • 82
    • 10244252625 scopus 로고    scopus 로고
    • Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein.
    • Lefebvre O, Chenard M, Masson R, Linares J, Dierich A, LeMeur M. et al. Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science 1996; 274: 259-262. Demonstrates that TFF-I (pS2) is essential for normal differentiation of the antral and pyloric gastric mucosa, and may function as a gastric-specific tumour suppressor gene.
    • (1996) Science , vol.274 , pp. 259
    • •Lefebvre, O.1    Chenard, M.2    Masson, R.3    Linares, J.4    Dierich, A.5    LeMeur, M.6
  • 83
    • 0030044720 scopus 로고    scopus 로고
    • Oral trefoil peptides protect against ethanol- and indomethacin-induced gastric injury in rats.
    • Babyatsky MW, DeBeaumont M, Thim L, Podolsky DK. Oral trefoil peptides protect against ethanol- and indomethacin-induced gastric injury in rats. Gastroenterology 1996; 110: 489-497. Demonstrates that topical TFF peptides protect the gastric mucosa against ethanol- and indomethacin-induced gastric injuries. The authors conclude that these peptides contribute to surface mucosal defence.
    • (1996) Gastroenterology , vol.110 , pp. 489
    • •Babyatsky, M.W.1    DeBeaumont, M.2    Thim, L.3    Podolsky, D.K.4
  • 84
    • 0028360991 scopus 로고
    • Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway.
    • Dignass A, Lynch-Devaney K, Kindon H, Thim L, Podolsky DK. Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway. J Clin Invest 1994; 94: 376-383. Demonstrates that TFF-II and TFF-III do not modulate intestinal epithelial proliferation, but that they enhance epithelial restitution through TGF-β-independent mechanisms, indicating that TFF peptides may play an important role in intestinal wound repair.
    • (1994) J Clin Invest , vol.94 , pp. 376
    • •Dignass, A.1    Lynch-Devaney, K.2    Kindon, H.3    Thim, L.4    Podolsky, D.K.5
  • 85
    • 0029828745 scopus 로고    scopus 로고
    • Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor.
    • Mashimo H, Wu DC, Podolsky DK, Fishman MC. Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor. Science 1996; 274: 262-265. Demonstrates impaired repair mechanisms in ITF (TFF-III) knock-out mice providing evidence for the important role that TFF peptides may play in the maintenance of the intestinal epithelial barrier and intestinal repair in vivo.
    • (1996) Science , vol.274 , pp. 262
    • ••Mashimo, H.1    Wu, D.C.2    Podolsky, D.K.3    Fishman, M.C.4
  • 86
    • 0029877816 scopus 로고    scopus 로고
    • Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage.
    • Playford RJ, Marchbank T, Goodlad RA, Chinery RA, Poulsom R, Hanby AM. Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage. Proc Natl Acad Sci USA 1996; 93: 2137-2142. Transgenic animal study that supports the hypothesis that TFF peptides are important in stimulating gastrointestinal repair.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2137
    • •Playford, R.J.1    Marchbank, T.2    Goodlad, R.A.3    Chinery, R.A.4    Poulsom, R.5    Hanby, A.M.6
  • 87
    • 13144266741 scopus 로고    scopus 로고
    • Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells.
    • Efstathiou JA, Noda M, Rowan A, Dixon C, Chinery R, Jawhari A. et al. Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. Proc Natl Acad Sci USA 1998; 95: 3122-3127.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3122
    • Efstathiou, J.A.1    Noda, M.2    Rowan, A.3    Dixon, C.4    Chinery, R.5    Jawhari, A.6
  • 88
    • 0031461322 scopus 로고    scopus 로고
    • Phosphorylation of beta-catenin and epidermal growth factor receptor by intestinal trefoil factor.
    • Liu D, el Hariry I, Karayiannakis AJ, Wilding J, Chinery R, Kmiot W. et al. Phosphorylation of beta-catenin and epidermal growth factor receptor by intestinal trefoil factor. Lab Invest 1997; 77: 557-563.
    • (1997) Lab Invest , vol.77 , pp. 557
    • Liu, D.1    el Hariry, I.2    Karayiannakis, A.J.3    Wilding, J.4    Chinery, R.5    Kmiot, W.6
  • 89
    • 0033967068 scopus 로고    scopus 로고
    • Overexpression of intestinal trefoil factor in human colon carcinoma cells reduces cellular growth in vitro and in vivo.
    • Uchino H, Kataoka H, Itoh H, Hamasuna R, Koono M. Overexpression of intestinal trefoil factor in human colon carcinoma cells reduces cellular growth in vitro and in vivo. Gastroenterology 2000; 118: 60-69. Demonstrates that overexpression of ITF suppresses the growth of colon carcinoma cells providing evidence that ITF may function as an inhibitory factor for the growth of colonic neoplasm.
    • (2000) Gastroenterology , vol.118 , pp. 60
    • •Uchino, H.1    Kataoka, H.2    Itoh, H.3    Hamasuna, R.4    Koono, M.5
  • 90
    • 0025837842 scopus 로고
    • Proliferation of gastrointestinal carcinoma cells by T-lymphocyte factors interleukin-3 and granulocyte-macrophage colony-stimulating-factor.
    • Dippold W, Meyer-zum-Büschenfelde KH. Proliferation of gastrointestinal carcinoma cells by T-lymphocyte factors interleukin-3 and granulocyte-macrophage colony-stimulating-factor. Immunol Res 1991; 10: 258-260.
    • (1991) Immunol Res , vol.10 , pp. 258
    • Dippold, W.1    Meyer-zum-Büschenfelde, K.H.2
  • 92
    • 0025805633 scopus 로고
    • Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product.
    • Bottaro DP, Rubin JS, Faletto DL. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 1991; 251: 802-804.
    • (1991) Science , vol.251 , pp. 802
    • Bottaro, D.P.1    Rubin, J.S.2    Faletto, D.L.3
  • 93
    • 0025999940 scopus 로고
    • Expression of the Met/HGF receptor in normal and neoplastic human tissue.
    • DiRenzo MF, Narsimhan RP, Olivero M. Expression of the Met/HGF receptor in normal and neoplastic human tissue. Oncogene 1991; 6: 1997-2003.
    • (1991) Oncogene , vol.6 , pp. 1997
    • DiRenzo, M.F.1    Narsimhan, R.P.2    Olivero, M.3
  • 94
    • 0028095407 scopus 로고
    • Hepatocyte growth factor/scatter factor modulates intestinal epithelial cell proliferation and migration.
    • Dignass AU, Lynch Devaney K, Podolsky DK. Hepatocyte growth factor/scatter factor modulates intestinal epithelial cell proliferation and migration. Biochem Biophys Res Commun 1994; 202: 701-709.
    • (1994) Biochem Biophys Res Commun , vol.202 , pp. 701
    • Dignass, A.U.1    Lynch Devaney, K.2    Podolsky, D.K.3
  • 95
    • 0031811114 scopus 로고    scopus 로고
    • Intestinal fibroblasts regulate intestinal epithelial cell proliferation via hepatocyte growth factor.
    • Goke M, Kanai M, Podolsky DK. Intestinal fibroblasts regulate intestinal epithelial cell proliferation via hepatocyte growth factor. Am J Physiol 1998; 274: G809-818. Demonstrates that fibroblasts stimulate intestinal epithelial proliferation through a paracrine mechanism mediated predominantly by HGF.
    • (1998) Am J Physiol , vol.274
    • •Goke, M.1    Kanai, M.2    Podolsky, D.K.3
  • 96
    • 0029147106 scopus 로고
    • Gene expression of keratinocyte and hepatocyte growth factors during the healing of rat gastric mucosal lesions.
    • Kinoshita Y, Nakata H, Hassan S, Asahara M, Kawanami C, Matsushima Y. et al. Gene expression of keratinocyte and hepatocyte growth factors during the healing of rat gastric mucosal lesions. Gastroenterology 1995; 109: 1068-1077.
    • (1995) Gastroenterology , vol.109 , pp. 1068
    • Kinoshita, Y.1    Nakata, H.2    Hassan, S.3    Asahara, M.4    Kawanami, C.5    Matsushima, Y.6
  • 97
    • 0345131685 scopus 로고    scopus 로고
    • Hepatocyte growth factor stimulates fetal gastric epithelial cell growth in vitro.
    • Kong W, Yee LF, Mulvihill SJ. Hepatocyte growth factor stimulates fetal gastric epithelial cell growth in vitro. J Surg Res 1998; 78: 161-168.
    • (1998) J Surg Res , vol.78 , pp. 161
    • Kong, W.1    Yee, L.F.2    Mulvihill, S.J.3
  • 98
    • 0028914930 scopus 로고
    • Hepatocyte growth factor is the most potent endogenous stimulant of rabbit gastric epithelial cell proliferation and migration in primary culture.
    • Takahashi M, Ota S, Shimada T, Hamada E, Kawabe T, Okudaira T. et al. Hepatocyte growth factor is the most potent endogenous stimulant of rabbit gastric epithelial cell proliferation and migration in primary culture. J Clin Invest 1995; 95: 1994-2003. Suggests that HGF may be a potent endogenous promoter of gastric epithelial cell proliferation and migration, and may contribute to gastric mucosal repair through a paracrine mechanism.
    • (1995) J Clin Invest , vol.95 , pp. 1994
    • •Takahashi, M.1    Ota, S.2    Shimada, T.3    Hamada, E.4    Kawabe, T.5    Okudaira, T.6
  • 100
    • 0027958885 scopus 로고
    • EGF stimulates both cyclooxygenase activity and cell proliferation of cultured guinea pig gastric mucous cells
    • Sakamoto C, Matsuda K, Nakano O, Konda Y, Matozaki T, Nishisaki H, Kasuga M. EGF stimulates both cyclooxygenase activity and cell proliferation of cultured guinea pig gastric mucous cells. J Gastroenterol 1994; 29 (suppl 7): 73-76.
    • (1994) J Gastroenterol , vol.29 , pp. 73
    • Sakamoto, C.1    Matsuda, K.2    Nakano, O.3    Konda, Y.4    Matozaki, T.5    Nishisaki, H.6    Kasuga, M.7
  • 102
    • 0031054237 scopus 로고    scopus 로고
    • Transforming growth factor-alpha (TGF-alpha) levels in human proximal gastrointestinal epithelium. Effect of mucosal injury and acid inhibition
    • Scheiman JM, Meise KS, Greenson JK, Coffey RJ. Transforming growth factor-alpha (TGF-alpha) levels in human proximal gastrointestinal epithelium. Effect of mucosal injury and acid inhibition. Dig Dis Sci 1997; 42: 333-341.
    • (1997) Dig Dis Sci , vol.42 , pp. 333
    • Scheiman, J.M.1    Meise, K.S.2    Greenson, J.K.3    Coffey, R.J.4
  • 103
    • 0025824483 scopus 로고
    • Goodlad RA, Raja KB, Peters TJ. Effects of urogastrone-epidermal growth factor on intestinal brush border enzymes and mitotic activity. Gut 1991; 32: 994-998.
    • (1991) Gut , vol.32 , pp. 994
    • Goodlad, R.A.1    Raja, K.B.2    Peters, T.J.3
  • 104
    • 0024985498 scopus 로고
    • Growth factors and oncogenes in human gastrointestinal carcinomas
    • Tahara E. Growth factors and oncogenes in human gastrointestinal carcinomas. J Cancer Res Clin Oncol 1990; 116: 121-131.
    • (1990) J Cancer Res Clin Oncol , vol.116 , pp. 121
    • Tahara, E.1
  • 105
    • 0026629491 scopus 로고
    • Basson MD, Modlin JM, Madri JA. Human enterocyte (Caco-2) migration is modulated in vitro by extra-cellular matrix composition and epidermal growth factor. J Clin Invest 1992; 90: 15-23.
    • (1992) J Clin Invest , vol.90 , pp. 15
    • Basson, M.D.1    Modlin, J.M.2    Madri, J.A.3
  • 106
    • 0025647695 scopus 로고
    • Transforming growth factor-α: a model for membrane anchored growth factors
    • Massague J. Transforming growth factor-α: a model for membrane anchored growth factors. J Biol Chem 1990; 265: 21 393-21 396.
    • (1990) J Biol Chem , vol.265
    • Massague, J.1
  • 108
    • 0026046265 scopus 로고
    • Regulation of transforming growth factor expression in rat intestinal epithelial cell lines
    • Suemori S, Ciacci C, Podolsky DK. Regulation of transforming growth factor expression in rat intestinal epithelial cell lines. J Clin Invest 1991; 87: 2216-2221.
    • (1991) J Clin Invest , vol.87 , pp. 2216
    • Suemori, S.1    Ciacci, C.2    Podolsky, D.K.3
  • 109
    • 0027160764 scopus 로고
    • Transforming growth factor β regulation of migration in wounded rat intestinal epithelial monolayers
    • Ciacci C, Lind SE, Podolsky DK. Transforming growth factor β regulation of migration in wounded rat intestinal epithelial monolayers. Gastroenterology 1993; 105: 93-101.
    • (1993) Gastroenterology , vol.105 , pp. 93
    • Ciacci, C.1    Lind, S.E.2    Podolsky, D.K.3
  • 110
    • 0029852154 scopus 로고    scopus 로고
    • Regulation and function of extracellular matrix intestinal epithelial restitution in vitro
    • Goke M, Zuk A, Podolsky DK. Regulation and function of extracellular matrix intestinal epithelial restitution in vitro. Am J Physiol 1996; 271: G729-740.
    • (1996) Am J Physiol , vol.271
    • Goke, M.1    Zuk, A.2    Podolsky, D.K.3
  • 112
    • 0025099263 scopus 로고
    • Transforming growth factor β1 has differential effects on B cell proliferation and activation antigen expression
    • Cross D, Cambier JC. Transforming growth factor β1 has differential effects on B cell proliferation and activation antigen expression. J Immunol 1990; 144: 432-439.
    • (1990) J Immunol , vol.144 , pp. 432
    • Cross, D.1    Cambier, J.C.2
  • 113
    • 0026025755 scopus 로고
    • Growth factors in development, transformation, and tumorigenesis
    • Cross M, Dexter TM. Growth factors in development, transformation, and tumorigenesis. Cell 1991; 64: 271-280.
    • (1991) Cell , vol.64 , pp. 271
    • Cross, M.1    Dexter, T.M.2
  • 114
    • 0029995799 scopus 로고    scopus 로고
    • Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance
    • Neurath MF, Fuss I, Kelsall BL, Presky DH, Waegell W, Strober W. Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance. J Exp Med 1996; 183: 2605-2616. Suggests that TGF-β production can abrogate experimental granulomatous colitis, and that regulation of TGF-β levels may be relevant in the treatment of human inflammatory bowel disease.
    • (1996) J Exp Med , vol.183 , pp. 2605
    • ••Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Presky, D.H.4    Waegell, W.5    Strober, W.6
  • 115
    • 0025953719 scopus 로고
    • Transforming growth factor β1, a potent chemoattractant for human neutrophils, bypasses classic signal-transduction pathways
    • Reibman J, Meixler S, Lee TC, Gold LI, Cronstein BN, Haines KA. et al. Transforming growth factor β1, a potent chemoattractant for human neutrophils, bypasses classic signal-transduction pathways. Proc Nat Acad Sci USA 1991; 88: 6805-6809.
    • (1991) Proc Nat Acad Sci USA , vol.88 , pp. 6805
    • Reibman, J.1    Meixler, S.2    Lee, T.C.3    Gold, L.I.4    Cronstein, B.N.5    Haines, K.A.6
  • 116
    • 0026516117 scopus 로고
    • Increased collagen type III synthesis by fibroblasts isolated from strictures of patients with Crohn's disease
    • Stallmach A, Schuppan D, Lazar D, Riese HH, Riecken E. Increased collagen type III synthesis by fibroblasts isolated from strictures of patients with Crohn's disease. Gastroenterology 1992; 102: 1920-1929.
    • (1992) Gastroenterology , vol.102 , pp. 1920
    • Stallmach, A.1    Schuppan, D.2    Lazar, D.3    Riese, H.H.4    Riecken, E.5
  • 117
    • 0025287480 scopus 로고
    • Transforming growth factor β1 selectively augments collagen synthesis by human intestinal smooth muscle cells
    • Graham MF, Bryson GR, Diegelmann RF. Transforming growth factor β1 selectively augments collagen synthesis by human intestinal smooth muscle cells. Gastroenterology 1990; 99: 447-453.
    • (1990) Gastroenterology , vol.99 , pp. 447
    • Graham, M.F.1    Bryson, G.R.2    Diegelmann, R.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.