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Volumn 142, Issue 18, 2015, Pages 3113-3125

Modeling mouse and human development using organoid cultures

Author keywords

3D organoid culture; Adult stem cell; Disease modeling; Embryonic stem cell; Genetic engineering

Indexed keywords

ENDONUCLEASE;

EID: 84942121762     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.118570     Document Type: Review
Times cited : (395)

References (130)
  • 1
    • 0029950724 scopus 로고    scopus 로고
    • The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice
    • Ahlgren, U., Jonsson, J. and Edlund, H. (1996). The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice. Development 122, 1409-1416.
    • (1996) Development , vol.122 , pp. 1409-1416
    • Ahlgren, U.1    Jonsson, J.2    Edlund, H.3
  • 3
    • 84900327361 scopus 로고    scopus 로고
    • Transplantation of embryonic and induced pluripotent stem cell-derived 3D retinal sheets into retinal degenerative mice
    • Assawachananont, J., Mandai, M., Okamoto, S., Yamada, C., Eiraku, M., Yonemura, S., Sasai, Y. and Takahashi, M. (2014). Transplantation of embryonic and induced pluripotent stem cell-derived 3D retinal sheets into retinal degenerative mice. Stem Cell Rep. 2, 662-674.
    • (2014) Stem Cell Rep , vol.2 , pp. 662-674
    • Assawachananont, J.1    Mandai, M.2    Okamoto, S.3    Yamada, C.4    Eiraku, M.5    Yonemura, S.6    Sasai, Y.7    Takahashi, M.8
  • 5
    • 78649639492 scopus 로고    scopus 로고
    • Tissue-resident adult stem cell populations of rapidly self-renewing organs
    • Barker, N., Bartfeld, S. and Clevers, H. (2010a). Tissue-resident adult stem cell populations of rapidly self-renewing organs. Cell Stem Cell 7, 656-670.
    • (2010) Cell Stem Cell , vol.7 , pp. 656-670
    • Barker, N.1    Bartfeld, S.2    Clevers, H.3
  • 7
    • 0011478490 scopus 로고
    • Three clonal types of keratinocyte with different capacities for multiplication
    • Barrandon, Y. and Green, H. (1987). Three clonal types of keratinocyte with different capacities for multiplication. Proc. Natl. Acad. Sci. USA 84, 2302-2306.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 2302-2306
    • Barrandon, Y.1    Green, H.2
  • 11
    • 0020960766 scopus 로고
    • Cytoplasmic activation of human nuclear genes in stable heterocaryons
    • Blau, H. M., Chiu, C.-P. and Webster, C. (1983). Cytoplasmic activation of human nuclear genes in stable heterocaryons. Cell 32, 1171-1180.
    • (1983) Cell , vol.32 , pp. 1171-1180
    • Blau, H.M.1    Chiu, C.-P.2    Webster, C.3
  • 14
    • 0021358883 scopus 로고
    • Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
    • Bradley, A., Evans, M., Kaufman, M. H. and Robertson, E. (1984). Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature 309, 255-256.
    • (1984) Nature , vol.309 , pp. 255-256
    • Bradley, A.1    Evans, M.2    Kaufman, M.H.3    Robertson, E.4
  • 17
    • 84864021917 scopus 로고    scopus 로고
    • LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/beta-catenin signaling. Mol. Cell
    • Carmon, K. S., Lin, Q., Gong, X., Thomas, A. and Liu, Q. (2012). LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/beta-catenin signaling. Mol. Cell. Biol. 32, 2054-2064.
    • (2012) Biol , vol.32 , pp. 2054-2064
    • Carmon, K.S.1    Lin, Q.2    Gong, X.3    Thomas, A.4    Liu, Q.5
  • 23
    • 0035072545 scopus 로고    scopus 로고
    • A bipotential precursor population for pancreas and liver within the embryonic endoderm
    • Deutsch, G., Jung, J., Zheng, M., Lora, J. and Zaret, K. S. (2001). A bipotential precursor population for pancreas and liver within the embryonic endoderm. Development 128, 871-881.
    • (2001) Development , vol.128 , pp. 871-881
    • Deutsch, G.1    Jung, J.2    Zheng, M.3    Lora, J.4    Zaret, K.S.5
  • 25
  • 31
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans, M. J. and Kaufman, M. H. (1981). Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154-156.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 32
    • 49349116007 scopus 로고    scopus 로고
    • Liver disease in alpha 1-antitrypsin deficiency: A review
    • quiz 2142
    • Fairbanks, K. D. and Tavill, A. S. (2008). Liver disease in alpha 1-antitrypsin deficiency: a review. Am. J. Gastroenterol. 103, 2136-2141; quiz 2142.
    • (2008) Am. J. Gastroenterol , vol.103 , pp. 2136-2141
    • Fairbanks, K.D.1    Tavill, A.S.2
  • 33
    • 25144500141 scopus 로고    scopus 로고
    • The molecular mechanisms of stomach development in vertebrates
    • Fukuda, K. and Yasugi, S. (2005). The molecular mechanisms of stomach development in vertebrates. Dev. Growth Differ. 47, 375-382.
    • (2005) Dev. Growth Differ , vol.47 , pp. 375-382
    • Fukuda, K.1    Yasugi, S.2
  • 36
    • 84905905141 scopus 로고    scopus 로고
    • An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells
    • González, F., Zhu, Z., Shi, Z.-D., Lelli, K., Verma, N., Li, Q. V. and Huangfu, D. (2014). An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells. Cell Stem Cell 15, 215-226.
    • (2014) Cell Stem Cell , vol.15 , pp. 215-226
    • González, F.1    Zhu, Z.2    Shi, Z.-D.3    Lelli, K.4    Verma, N.5    Li, Q.V.6    Huangfu, D.7
  • 38
    • 0000331391 scopus 로고
    • Adult frogs derived from the nuclei of single somatic cells
    • Gurdon, J. B. (1962). Adult frogs derived from the nuclei of single somatic cells. Dev. Biol. 4, 256-273.
    • (1962) Dev. Biol , vol.4 , pp. 256-273
    • Gurdon, J.B.1
  • 39
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick, L. (1965). The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37, 614-636.
    • (1965) Exp. Cell Res , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 40
    • 84889563027 scopus 로고    scopus 로고
    • Establishment of a novel lingual organoid culture system: Generation of organoids having mature keratinized epithelium from adult epithelial stem cells
    • Hisha, H., Tanaka, T., Kanno, S., Tokuyama, Y., Komai, Y., Ohe, S., Yanai, H., Omachi, T. and Ueno, H. (2013). Establishment of a novel lingual organoid culture system: generation of organoids having mature keratinized epithelium from adult epithelial stem cells. Sci. Rep. 3, 3224.
    • (2013) Sci. Rep , vol.3 , pp. 3224
    • Hisha, H.1    Tanaka, T.2    Kanno, S.3    Tokuyama, Y.4    Komai, Y.5    Ohe, S.6    Yanai, H.7    Omachi, T.8    Ueno, H.9
  • 42
    • 82955161638 scopus 로고    scopus 로고
    • Generating intestinal tissue from stem cells: Potential for research and therapy
    • Howell, J. C. and Wells, J. M. (2011). Generating intestinal tissue from stem cells: potential for research and therapy. Regen. Med. 6, 743-755.
    • (2011) Regen. Med , vol.6 , pp. 743-755
    • Howell, J.C.1    Wells, J.M.2
  • 47
    • 0034425478 scopus 로고    scopus 로고
    • Three-dimensional cellular development is essential for ex vivo formation of human bone. Nat
    • Kale, S., Biermann, S., Edwards, C., Tarnowski, C., Morris, M. and Long, M. W. (2000). Three-dimensional cellular development is essential for ex vivo formation of human bone. Nat. Biotechnol. 18, 954-958.
    • (2000) Biotechnol , vol.18 , pp. 954-958
    • Kale, S.1    Biermann, S.2    Edwards, C.3    Tarnowski, C.4    Morris, M.5    Long, M.W.6
  • 48
    • 0027253264 scopus 로고
    • Dynamics of epithelial cells in the corpus of the mouse stomach. I. Identification of proliferative cell types and pinpointing of the stem cell
    • Karam, S. M., and Leblond, C. P. (1993). Dynamics of epithelial cells in the corpus of the mouse stomach. I. Identification of proliferative cell types and pinpointing of the stem cell. Anat. Rec. 236, 259-279.
    • (1993) Anat. Rec , vol.236 , pp. 259-279
    • Karam, S.M.1    Leblond, C.P.2
  • 50
    • 16244363710 scopus 로고    scopus 로고
    • The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling
    • Kim, B.-M., Buchner, G., Miletich, I., Sharpe, P. T. and Shivdasani, R. A. (2005). The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling. Dev. Cell 8, 611-622.
    • (2005) Dev. Cell , vol.8 , pp. 611-622
    • Kim, B.-M.1    Buchner, G.2    Miletich, I.3    Sharpe, P.T.4    Shivdasani, R.A.5
  • 51
    • 84881474378 scopus 로고    scopus 로고
    • Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture
    • Koehler, K. R., Mikosz, A. M., Molosh, A. I., Patel, D. and Hashino, E. (2013). Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture. Nature 500, 217-221.
    • (2013) Nature , vol.500 , pp. 217-221
    • Koehler, K.R.1    Mikosz, A.M.2    Molosh, A.I.3    Patel, D.4    Hashino, E.5
  • 52
    • 0031848068 scopus 로고    scopus 로고
    • Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
    • Korinek, V., Barker, N., Moerer, P., van Donselaar, E., Huls, G., Peters, P. J. and Clevers, H. (1998). Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat. Genet. 19, 379-383.
    • (1998) Nat. Genet , vol.19 , pp. 379-383
    • Korinek, V.1    Barker, N.2    Moerer, P.3    Van Donselaar, E.4    Huls, G.5    Peters, P.J.6    Clevers, H.7
  • 54
    • 84923365108 scopus 로고    scopus 로고
    • Generation of a ciliary margin-like stem cell niche from self-organizing human retinal tissue
    • Kuwahara, A., Ozone, C., Nakano, T., Saito, K., Eiraku, M. and Sasai, Y. (2015). Generation of a ciliary margin-like stem cell niche from self-organizing human retinal tissue. Nat. Commun. 6, 6286.
    • (2015) Nat. Commun , vol.6 , pp. 6286
    • Kuwahara, A.1    Ozone, C.2    Nakano, T.3    Saito, K.4    Eiraku, M.5    Sasai, Y.6
  • 55
    • 0018322420 scopus 로고
    • Stem cell concepts
    • Lajtha, L. G. (1979). Stem cell concepts. Differentiation 14, 23-33.
    • (1979) Differentiation , vol.14 , pp. 23-33
    • Lajtha, L.G.1
  • 56
    • 0035913986 scopus 로고    scopus 로고
    • Induction of pancreatic differentiation by signals from blood vessels
    • Lammert, E., Cleaver, O. and Melton, D. (2001). Induction of pancreatic differentiation by signals from blood vessels. Science 294, 564-567.
    • (2001) Science , vol.294 , pp. 564-567
    • Lammert, E.1    Cleaver, O.2    Melton, D.3
  • 57
    • 84904396621 scopus 로고    scopus 로고
    • Organogenesis in a dish: Modeling development and disease using organoid technologies
    • Lancaster, M. A. and Knoblich, J. A. (2014). Organogenesis in a dish: modeling development and disease using organoid technologies. Science 345, 1247125.
    • (2014) Science , vol.345
    • Lancaster, M.A.1    Knoblich, J.A.2
  • 59
    • 0020071305 scopus 로고
    • Division of the mouse gastric mucosa into zymogenic and mucous regions on the basis of gland features
    • Lee, E. R., Trasler, J., Dwivedi, S. and Leblond, C. P. (1982). Division of the mouse gastric mucosa into zymogenic and mucous regions on the basis of gland features. Am. J. Anat. 164, 187-207.
    • (1982) Am. J. Anat , vol.164 , pp. 187-207
    • Lee, E.R.1    Trasler, J.2    Dwivedi, S.3    Leblond, C.P.4
  • 62
    • 84881186856 scopus 로고    scopus 로고
    • Genetic and epigenetic variations in iPSCs: Potential causes and implications for application
    • Liang, G. and Zhang, Y. (2013). Genetic and epigenetic variations in iPSCs: potential causes and implications for application. Cell Stem Cell 13, 149-159.
    • (2013) Cell Stem Cell , vol.13 , pp. 149-159
    • Liang, G.1    Zhang, Y.2
  • 65
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin, G. R. (1981). Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. USA 78, 7634-7638.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 7634-7638
    • Martin, G.R.1
  • 66
    • 0025881125 scopus 로고
    • Hepatocyte growth factor: Molecular structure and implications for a central role in liver regeneration
    • Matsumoto, K. and Nakamura, T. (1991). Hepatocyte growth factor: molecular structure and implications for a central role in liver regeneration. J. Gastroenterol. Hepatol. 6, 509-519.
    • (1991) J. Gastroenterol. Hepatol , vol.6 , pp. 509-519
    • Matsumoto, K.1    Nakamura, T.2
  • 68
    • 0036339631 scopus 로고    scopus 로고
    • A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency
    • McCright, B., Lozier, J. and Gridley, T. (2002). A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency. Development 129, 1075-1082.
    • (2002) Development , vol.129 , pp. 1075-1082
    • McCright, B.1    Lozier, J.2    Gridley, T.3
  • 69
    • 84899557440 scopus 로고    scopus 로고
    • The liver is a peculiar organ when it comes to stem cells
    • Michalopoulos, G. K. (2014). The liver is a peculiar organ when it comes to stem cells. Am. J. Pathol. 184, 1263-1267.
    • (2014) Am. J. Pathol , vol.184 , pp. 1263-1267
    • Michalopoulos, G.K.1
  • 70
    • 0035149354 scopus 로고    scopus 로고
    • Histological organization in hepatocyte organoid cultures
    • Michalopoulos, G. K., Bowen, W. C., Mulè, K. and Stolz, D. B. (2001). Histological organization in hepatocyte organoid cultures. Am. J. Pathol. 159, 1877-1887.
    • (2001) Am. J. Pathol , vol.159 , pp. 1877-1887
    • Michalopoulos, G.K.1    Bowen, W.C.2    Mulè, K.3    Stolz, D.B.4
  • 71
    • 84899729602 scopus 로고    scopus 로고
    • Stem/progenitor cells in liver development, homeostasis, regeneration, and reprogramming
    • Miyajima, A., Tanaka, M. and Itoh, T. (2014). Stem/progenitor cells in liver development, homeostasis, regeneration, and reprogramming. Cell Stem Cell 14, 561-574.
    • (2014) Cell Stem Cell , vol.14 , pp. 561-574
    • Miyajima, A.1    Tanaka, M.2    Itoh, T.3
  • 72
    • 0035032989 scopus 로고    scopus 로고
    • Changes in WNT/beta-catenin pathway during regulated growth in rat liver regeneration
    • Monga, S. P. S., Pediaditakis, P., Mule, K., Stolz, D. B. and Michalopoulos, G. K. (2001). Changes in WNT/beta-catenin pathway during regulated growth in rat liver regeneration. Hepatology 33, 1098-1109.
    • (2001) Hepatology , vol.33 , pp. 1098-1109
    • Monga, S.P.S.1    Pediaditakis, P.2    Mule, K.3    Stolz, D.B.4    Michalopoulos, G.K.5
  • 73
    • 84922791023 scopus 로고    scopus 로고
    • Self-organization of polarized cerebellar tissue in 3D culture of human pluripotent stem cells
    • Muguruma, K., Nishiyama, A., Kawakami, H., Hashimoto, K. and Sasai, Y. (2015). Self-organization of polarized cerebellar tissue in 3D culture of human pluripotent stem cells. Cell Rep. 10, 537-550.
    • (2015) Cell Rep , vol.10 , pp. 537-550
    • Muguruma, K.1    Nishiyama, A.2    Kawakami, H.3    Hashimoto, K.4    Sasai, Y.5
  • 77
    • 33846910009 scopus 로고    scopus 로고
    • FGF10 signaling controls stomach morphogenesis
    • Nyeng, P., Norgaard, G. A., Kobberup, S. and Jensen, J. (2007). FGF10 signaling controls stomach morphogenesis. Dev. Biol. 303, 295-310.
    • (2007) Dev. Biol , vol.303 , pp. 295-310
    • Nyeng, P.1    Norgaard, G.A.2    Kobberup, S.3    Jensen, J.4
  • 78
    • 0034685651 scopus 로고    scopus 로고
    • An air–liquid interface promotes the differentiation of gastric surface mucous cells (GSM06) in culture
    • Ootani, A., Toda, S., Fujimoto, K. and Sugihara, H. (2000). An air–liquid interface promotes the differentiation of gastric surface mucous cells (GSM06) in culture. Biochem. Biophys. Res. Commun. 271, 741-746.
    • (2000) Biochem. Biophys. Res. Commun , vol.271 , pp. 741-746
    • Ootani, A.1    Toda, S.2    Fujimoto, K.3    Sugihara, H.4
  • 80
    • 0038523969 scopus 로고    scopus 로고
    • Chimeric nucleases stimulate gene targeting in human cells
    • Porteus, M. H. and Baltimore, D. (2003). Chimeric nucleases stimulate gene targeting in human cells. Science 300, 763.
    • (2003) Science , vol.300 , pp. 763
    • Porteus, M.H.1    Baltimore, D.2
  • 83
    • 0033916281 scopus 로고    scopus 로고
    • Hedgehog signals regulate multiple aspects of gastrointestinal development
    • Ramalho-Santos, M., Melton, D. A. and McMahon, A. P. (2000). Hedgehog signals regulate multiple aspects of gastrointestinal development. Development 127, 2763-2772.
    • (2000) Development , vol.127 , pp. 2763-2772
    • Ramalho-Santos, M.1    Melton, D.A.2    McMahon, A.P.3
  • 84
    • 0028061666 scopus 로고
    • Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease
    • Rouet, P., Smih, F. and Jasin, M. (1994). Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. Mol. Cell. Biol. 14, 8096-8106.
    • (1994) Mol. Cell. Biol , vol.14 , pp. 8096-8106
    • Rouet, P.1    Smih, F.2    Jasin, M.3
  • 85
    • 84905815332 scopus 로고    scopus 로고
    • Loss of Fbw7 reprograms adult pancreatic ductal cells into alpha, delta, and beta cells
    • Sancho, R., Gruber, R., Gu, G. and Behrens, A. (2014). Loss of Fbw7 reprograms adult pancreatic ductal cells into alpha, delta, and beta cells. Cell Stem Cell 15, 139-153.
    • (2014) Cell Stem Cell , vol.15 , pp. 139-153
    • Sancho, R.1    Gruber, R.2    Gu, G.3    Behrens, A.4
  • 86
    • 46249128798 scopus 로고    scopus 로고
    • Bmi1 is expressed in vivo in intestinal stem cells
    • Sangiorgi, E. and Capecchi, M. R. (2008). Bmi1 is expressed in vivo in intestinal stem cells. Nat. Genet. 40, 915-920.
    • (2008) Nat. Genet , vol.40 , pp. 915-920
    • Sangiorgi, E.1    Capecchi, M.R.2
  • 87
    • 84877275352 scopus 로고    scopus 로고
    • Next-generation regenerative medicine: Organogenesis from stem cells in 3D culture
    • Sasai, Y. (2013). Next-generation regenerative medicine: organogenesis from stem cells in 3D culture. Cell Stem Cell 12, 520-530.
    • (2013) Cell Stem Cell , vol.12 , pp. 520-530
    • Sasai, Y.1
  • 88
    • 84867865709 scopus 로고    scopus 로고
    • In vitro organogenesis in three dimensions: Self-organising stem cells
    • Sasai, Y., Eiraku, M. and Suga, H. (2012). In vitro organogenesis in three dimensions: self-organising stem cells. Development 139, 4111-4121.
    • (2012) Development , vol.139 , pp. 4111-4121
    • Sasai, Y.1    Eiraku, M.2    Suga, H.3
  • 89
    • 84878760040 scopus 로고    scopus 로고
    • Growing self-organizing mini-guts from a single intestinal stem cell: Mechanism and applications
    • Sato, T. and Clevers, H. (2013). Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 340, 1190-1194.
    • (2013) Science , vol.340 , pp. 1190-1194
    • Sato, T.1    Clevers, H.2
  • 92
    • 84908355955 scopus 로고    scopus 로고
    • Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury
    • Schaub, J. R., Malato, Y., Gormond, C. and Willenbring, H. (2014). Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury. Cell Rep. 8, 933-939.
    • (2014) Cell Rep , vol.8 , pp. 933-939
    • Schaub, J.R.1    Malato, Y.2    Gormond, C.3    Willenbring, H.4
  • 103
    • 66249089481 scopus 로고    scopus 로고
    • Scaffold-free human cardiac tissue patch created from embryonic stem cells
    • Stevens, K. R., Pabon, L., Muskheli, V. and Murry, C. E. (2009). Scaffold-free human cardiac tissue patch created from embryonic stem cells. Tissue Eng. A 15, 1211-1222.
    • (2009) Tissue Eng. A , vol.15 , pp. 1211-1222
    • Stevens, K.R.1    Pabon, L.2    Muskheli, V.3    Murry, C.E.4
  • 106
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi, K. and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 107
    • 84873020006 scopus 로고    scopus 로고
    • FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration
    • Takase, H. M., Itoh, T., Ino, S., Wang, T., Koji, T., Akira, S., Takikawa, Y. and Miyajima, A. (2013). FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration. Genes Dev. 27, 169-181.
    • (2013) Genes Dev , vol.27 , pp. 169-181
    • Takase, H.M.1    Itoh, T.2    Ino, S.3    Wang, T.4    Koji, T.5    Akira, S.6    Takikawa, Y.7    Miyajima, A.8
  • 108
    • 83255193921 scopus 로고    scopus 로고
    • Interconversion between intestinal stem cell populations in distinct niches
    • Takeda, N., Jain, R., LeBoeuf, M. R., Wang, Q., Lu, M. M. and Epstein, J. A. (2011). Interconversion between intestinal stem cell populations in distinct niches. Science 334, 1420-1424.
    • (2011) Science , vol.334 , pp. 1420-1424
    • Takeda, N.1    Jain, R.2    Leboeuf, M.R.3    Wang, Q.4    Lu, M.M.5    Epstein, J.A.6
  • 110
    • 84903279458 scopus 로고    scopus 로고
    • Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury
    • Tarlow, B. D., Finegold, M. J. and Grompe, M. (2014). Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury. Hepatology 60, 278-289.
    • (2014) Hepatology , vol.60 , pp. 278-289
    • Tarlow, B.D.1    Finegold, M.J.2    Grompe, M.3
  • 111
    • 0023646810 scopus 로고
    • Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells
    • Thomas, K. R. and Capecchi, M. R. (1987). Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51, 503-512.
    • (1987) Cell , vol.51 , pp. 503-512
    • Thomas, K.R.1    Capecchi, M.R.2
  • 113
    • 80054041585 scopus 로고    scopus 로고
    • A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
    • Tian, H., Biehs, B., Warming, S., Leong, K. G., Rangell, L., Klein, O. D. and de Sauvage, F. J. (2011). A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature 478, 255-259.
    • (2011) Nature , vol.478 , pp. 255-259
    • Tian, H.1    Biehs, B.2    Warming, S.3    Leong, K.G.4    Rangell, L.5    Klein, O.D.6    De Sauvage, F.J.7
  • 116
    • 67649240439 scopus 로고    scopus 로고
    • OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells
    • van der Flier, L. G., Haegebarth, A., Stange, D. E., van de Wetering, M. and Clevers, H. (2009). OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells. Gastroenterology 137, 15-17.
    • (2009) Gastroenterology , vol.137 , pp. 15-17
    • Van Der Flier, L.G.1    Haegebarth, A.2    Stange, D.E.3    Van De Wetering, M.4    Clevers, H.5
  • 118
    • 77956614336 scopus 로고    scopus 로고
    • Stem cells and cancer of the stomach and intestine
    • Vries, R. G. J., Huch, M. and Clevers, H. (2010). Stem cells and cancer of the stomach and intestine. Mol. Oncol. 4, 373-384.
    • (2010) Mol. Oncol , vol.4 , pp. 373-384
    • Vries, R.G.J.1    Huch, M.2    Clevers, H.3
  • 119
    • 67649995217 scopus 로고    scopus 로고
    • Dynamic signaling network for the specification of embryonic pancreas and liver progenitors
    • Wandzioch, E. and Zaret, K. S. (2009). Dynamic signaling network for the specification of embryonic pancreas and liver progenitors. Science 324, 1707-1710.
    • (2009) Science , vol.324 , pp. 1707-1710
    • Wandzioch, E.1    Zaret, K.S.2
  • 120
    • 84893283877 scopus 로고    scopus 로고
    • How to make an intestine
    • Wells, J. M. and Spence, J. R. (2014). How to make an intestine. Development 141, 752-760.
    • (2014) Development , vol.141 , pp. 752-760
    • Wells, J.M.1    Spence, J.R.2
  • 122
    • 36249006969 scopus 로고    scopus 로고
    • Selfrenewal and multilineage differentiation in vitro from murine prostate stem cells
    • Xin, L., Lukacs, R. U., Lawson, D. A., Cheng, D. and Witte, O. N. (2007). Selfrenewal and multilineage differentiation in vitro from murine prostate stem cells. Stem Cells 25, 2760-2769.
    • (2007) Stem Cells , vol.25 , pp. 2760-2769
    • Xin, L.1    Lukacs, R.U.2    Lawson, D.A.3    Cheng, D.4    Witte, O.N.5
  • 126
    • 57349112286 scopus 로고    scopus 로고
    • Generation and regeneration of cells of the liver and pancreas
    • Zaret, K. S. and Grompe, M. (2008). Generation and regeneration of cells of the liver and pancreas. Science 322, 1490-1494.
    • (2008) Science , vol.322 , pp. 1490-1494
    • Zaret, K.S.1    Grompe, M.2
  • 127
    • 84855901401 scopus 로고    scopus 로고
    • October 31, 2008StemBook, ed. The Stem Cell Research Community, StemBook
    • Zorn, A. M. (2008). Liver development (October 31, 2008), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.25.1, http://www.stembook.org.
    • (2008) Liver Development
    • Zorn, A.M.1
  • 128
    • 70350225535 scopus 로고    scopus 로고
    • Vertebrate endoderm development and organ formation
    • Zorn, A. M. and Wells, J. M. (2009). Vertebrate endoderm development and organ formation. Annu. Rev. Cell Dev. Biol. 25, 221-251.
    • (2009) Annu. Rev. Cell Dev. Biol , vol.25 , pp. 221-251
    • Zorn, A.M.1    Wells, J.M.2
  • 130
    • 80055069793 scopus 로고    scopus 로고
    • Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease
    • Zou, J., Mali, P., Huang, X., Dowey, S. N. and Cheng, L. (2011). Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease. Blood 118, 4599-4608.
    • (2011) Blood , vol.118 , pp. 4599-4608
    • Zou, J.1    Mali, P.2    Huang, X.3    Dowey, S.N.4    Cheng, L.5


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