Medicine: Mitogenic influence of human R-spondin1 on the intestinal epithelium

Science

Volumn 309, Issue 5738, 2005, Pages 1256-1259

  Kim, Kyung Ah ^a   Kakitani, Makoto ^b   Zhao, Jingsong ^a   Oshima, Takeshi ^b   Tang, Tom ^a   Binnerts, Minke ^a   Liu, Yi ^a   Boyle, Bryan ^a   Park, Emily ^a   Emtage, Peter ^a   Funk, Walter D ^a   Tomizuka, Kazuma ^b  

^a Nuvelo Inc   (United States)

^b KIRIN BREWERY CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; LIVING SYSTEMS STUDIES; TISSUE;

CRYPT CELLS; HUMAN GENE; INTESTINE; MITOGENIC INFLUENCE;

DRUG PRODUCTS;

BETA CATENIN; GENE PRODUCT; GROWTH FACTOR; R SPONDIN1; THROMBOSPONDIN; UNCLASSIFIED DRUG; WNT PROTEIN; ANTINEOPLASTIC AGENT; CATNB PROTEIN, MOUSE; CTNNB1 PROTEIN, HUMAN; CYTOSKELETON PROTEIN; FGF7 PROTEIN, HUMAN; FGF7 PROTEIN, MOUSE; FIBROBLAST GROWTH FACTOR; FLUOROURACIL; GLUCAGON LIKE PEPTIDE; GLUCAGON-LIKE-IMMUNOREACTIVITY; KERATINOCYTE GROWTH FACTOR; MITOGENIC AGENT; PEPTIDE; PROTEIN; RECOMBINANT PROTEIN; RSPO1 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; WNT3 PROTEIN;

MEDICINE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; ENDOCRINE CELL; EPITHELIUM CELL; GASTROINTESTINAL DISEASE; HUMAN; HUMAN CELL; INTESTINE CRYPT; INTESTINE EPITHELIUM; MITOGENESIS; MODEL; MOUSE; MUCOSA INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; ANIMAL; CANCER TRANSPLANTATION; CELL LINE; CHIMERA; COLON; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; ENTEROENDOCRINE CELL; EXPERIMENTAL NEOPLASM; GENETICS; INTESTINE MUCOSA; METABOLISM; PATHOLOGY; PHYSIOLOGY; SMALL INTESTINE; TONGUE; TUMOR CELL LINE;

ANIMALIA; MUS MUSCULUS;

ANIMALS; ANTINEOPLASTIC AGENTS; BETA CATENIN; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; CHIMERA; COLON; CYTOSKELETAL PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROENDOCRINE CELLS; EPITHELIAL CELLS; FIBROBLAST GROWTH FACTOR 7; FIBROBLAST GROWTH FACTORS; FLUOROURACIL; GLUCAGON-LIKE PEPTIDES; HUMANS; INTESTINAL MUCOSA; INTESTINE, SMALL; MICE; MICE, TRANSGENIC; MITOGENS; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; PEPTIDES; PROTEINS; RECOMBINANT PROTEINS; THROMBOSPONDINS; TONGUE; TRANS-ACTIVATORS; WNT PROTEINS;

EID: 23844455584     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1112521     Document Type: Article

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