메뉴 건너뛰기




Volumn 144, Issue 6, 2017, Pages 952-957

Using brain organoids to understand Zika virus-induced microcephaly

Author keywords

Cortex; iPSC; Microcephaly; Organoids; Zika

Indexed keywords

ARTICLE; BRAIN; CYTOPLASM; HUMAN; MICROCEPHALY; NONHUMAN; PANDEMIC; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; ZIKA FEVER; ZIKA VIRUS; ANIMAL; PATHOLOGY; PHYSIOLOGY; VIROLOGY;

EID: 85015296935     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.140707     Document Type: Article
Times cited : (181)

References (42)
  • 3
    • 84959262866 scopus 로고    scopus 로고
    • CDC, Atlanta, GA: US Department of Health and Human Services, United States Centers for Disease Control and Prevention
    • CDC (2016). Zika virus. Atlanta, GA: US Department of Health and Human Services, United States Centers for Disease Control and Prevention. https://www.cdc.gov/zika/index.html.
    • (2016) Zika Virus
  • 5
    • 84971557656 scopus 로고    scopus 로고
    • Zika virus depletes neural progenitors in human cerebral organoids through activation of the innate immune receptor TLR3
    • Dang, J., Tiwari, S. K., Lichinchi, G., Qin, Y., Patil, V. S., Eroshkin, A. M. and Rana, T. M. (2016). Zika virus depletes neural progenitors in human cerebral organoids through activation of the innate immune receptor TLR3. Cell Stem Cell 19, 258-265.
    • (2016) Cell Stem Cell , vol.19 , pp. 258-265
    • Dang, J.1    Tiwari, S.K.2    Lichinchi, G.3    Qin, Y.4    Patil, V.S.5    Eroshkin, A.M.6    Rana, T.M.7
  • 8
    • 84957917366 scopus 로고    scopus 로고
    • Zika virus in the Americas–yet another arbovirus threat
    • Fauci, A. S. and Morens, D. M. (2016). Zika virus in the Americas–yet another arbovirus threat. N. Engl. J. Med. 374, 601-604.
    • (2016) N. Engl. J. Med , vol.374 , pp. 601-604
    • Fauci, A.S.1    Morens, D.M.2
  • 10
    • 84971668027 scopus 로고    scopus 로고
    • Western Zika virus in human fetal neural progenitors persists long term with partial cytopathic and limited immunogenic effects
    • Hanners, N. W., Eitson, J. L., Usui, N., Richardson, R. B., Wexler, E. M., Konopka, G. and Schoggins, J. W. (2016). Western Zika virus in human fetal neural progenitors persists long term with partial cytopathic and limited immunogenic effects. Cell Rep. 15, 2315-2322.
    • (2016) Cell Rep , vol.15 , pp. 2315-2322
    • Hanners, N.W.1    Eitson, J.L.2    Usui, N.3    Richardson, R.B.4    Wexler, E.M.5    Konopka, G.6    Schoggins, J.W.7
  • 13
    • 84979790139 scopus 로고    scopus 로고
    • Midbrain-like organoids from human pluripotent stem cells contain functional dopaminergic and neuromelaninproducing neurons
    • Jo, J., Xiao, Y., Sun, A. X., Cukuroglu, E., Tran, H.-D., Göke, J., Tan, Z. Y., Saw, T. Y., Tan, C.-P., Lokman, H. et al. (2016). Midbrain-like organoids from human pluripotent stem cells contain functional dopaminergic and neuromelaninproducing neurons. Cell Stem Cell 19, 248-257.
    • (2016) Cell Stem Cell , vol.19 , pp. 248-257
    • Jo, J.1    Xiao, Y.2    Sun, A.X.3    Cukuroglu, E.4    Tran, H.-D.5    Göke, J.6    Tan, Z.Y.7    Saw, T.Y.8    Tan, C.-P.9    Lokman, H.10
  • 14
    • 84890282623 scopus 로고    scopus 로고
    • Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex
    • Kadoshima, T., Sakaguchi, H., Nakano, T., Soen, M., Ando, S., Eiraku, M. and Sasai, Y. (2013). Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex. Proc. Natl. Acad. Sci. USA 110, 20284-20289.
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 20284-20289
    • Kadoshima, T.1    Sakaguchi, H.2    Nakano, T.3    Soen, M.4    Ando, S.5    Eiraku, M.6    Sasai, Y.7
  • 15
    • 84971500254 scopus 로고    scopus 로고
    • Stem cell models of human brain development
    • Kelava, I. and Lancaster, M. A. (2016). Stem cell models of human brain development. Cell Stem Cell 18, 736-748.
    • (2016) Cell Stem Cell , vol.18 , pp. 736-748
    • Kelava, I.1    Lancaster, M.A.2
  • 17
    • 84970023750 scopus 로고    scopus 로고
    • Zika virus disrupts neural progenitor development and leads to microcephaly in mice
    • Li, C., Xu, D., Ye, Q., Hong, S., Jiang, Y., Liu, X., Zhang, N., Shi, L., Qin, C.-F. and Xu, Z. (2016). Zika virus disrupts neural progenitor development and leads to microcephaly in mice. Cell Stem Cell 19, 120-126.
    • (2016) Cell Stem Cell , vol.19 , pp. 120-126
    • Li, C.1    Xu, D.2    Ye, Q.3    Hong, S.4    Jiang, Y.5    Liu, X.6    Zhang, N.7    Shi, L.8    Qin, C.-F.9    Xu, Z.10
  • 18
    • 84981742269 scopus 로고    scopus 로고
    • Zika virus NS4A and NS4B proteins deregulate Akt-mTOR signaling in human fetal neural stem cells to inhibit neurogenesis and induce autophagy
    • Liang, Q., Luo, Z., Zeng, J., Chen, W., Foo, S.-S., Lee, S.-A., Ge, J., Wang, S., Goldman, S. A., Zlokovic, B. V. et al. (2016). Zika virus NS4A and NS4B proteins deregulate Akt-mTOR signaling in human fetal neural stem cells to inhibit neurogenesis and induce autophagy. Cell Stem Cell 19, 663-671.
    • (2016) Cell Stem Cell , vol.19 , pp. 663-671
    • Liang, Q.1    Luo, Z.2    Zeng, J.3    Chen, W.4    Foo, S.-S.5    Lee, S.-A.6    Ge, J.7    Wang, S.8    Goldman, S.A.9    Zlokovic, B.V.10
  • 19
    • 79959924122 scopus 로고    scopus 로고
    • Development and evolution of the human neocortex
    • Lui, J. H., Hansen, D. V. and Kriegstein, A. R. (2011). Development and evolution of the human neocortex. Cell 146, 18-36.
    • (2011) Cell , vol.146 , pp. 18-36
    • Lui, J.H.1    Hansen, D.V.2    Kriegstein, A.R.3
  • 21
    • 84922571348 scopus 로고    scopus 로고
    • Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells
    • Merkle, F. T., Maroof, A., Wataya, T., Sasai, Y., Studer, L., Eggan, K. and Schier, A. F. (2015). Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells. Development 142, 633-643.
    • (2015) Development , vol.142 , pp. 633-643
    • Merkle, F.T.1    Maroof, A.2    Wataya, T.3    Sasai, Y.4    Studer, L.5    Eggan, K.6    Schier, A.F.7
  • 22
    • 85000761506 scopus 로고    scopus 로고
    • Advances in Zika virus research: Stem cell models, challenges, and opportunities
    • Ming, G.-l., Tang, H. and Song, H. (2016). Advances in Zika virus research: stem cell models, challenges, and opportunities. Cell Stem Cell 19, 690-702.
    • (2016) Cell Stem Cell , vol.19 , pp. 690-702
    • Ming, G.-L.1    Tang, H.2    Song, H.3
  • 24
    • 84973650202 scopus 로고    scopus 로고
    • Neural stem cells attacked by Zika virus
    • Nguyen, H. N., Qian, X., Song, H. and Ming, G.-l. (2016). Neural stem cells attacked by Zika virus. Cell Res. 26, 753-754.
    • (2016) Cell Res , vol.26 , pp. 753-754
    • Nguyen, H.N.1    Qian, X.2    Song, H.3    Ming, G.-L.4
  • 26
    • 84991263060 scopus 로고    scopus 로고
    • Transformation of the radial glia scaffold demarcates two stages of human cerebral cortex development
    • Nowakowski, T. J., Pollen, A. A., Sandoval-Espinosa, C. and Kriegstein, A. R. (2016b). Transformation of the radial glia scaffold demarcates two stages of human cerebral cortex development. Neuron 91, 1219-1227.
    • (2016) Neuron , vol.91 , pp. 1219-1227
    • Nowakowski, T.J.1    Pollen, A.A.2    Sandoval-Espinosa, C.3    Kriegstein, A.R.4
  • 29
    • 84957796532 scopus 로고    scopus 로고
    • Rapid spread of Zika virus in the Americas-implications for public health preparedness for mass gatherings at the 2016 Brazil Olympic Games
    • Petersen, E., Wilson, M. E., Touch, S., McCloskey, B., Mwaba, P., Bates, M., Dar, O., Mattes, F., Kidd, M., Ippolito, G. et al. (2016). Rapid spread of Zika virus in the Americas-implications for public health preparedness for mass gatherings at the 2016 Brazil Olympic Games. Int. J. Infect. Dis. 44, 11-15.
    • (2016) Int. J. Infect. Dis , vol.44 , pp. 11-15
    • Petersen, E.1    Wilson, M.E.2    Touch, S.3    McCloskey, B.4    Mwaba, P.5    Bates, M.6    Dar, O.7    Mattes, F.8    Kidd, M.9    Ippolito, G.10
  • 32
    • 84947292300 scopus 로고    scopus 로고
    • Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue
    • Sakaguchi, H., Kadoshima, T., Soen, M., Narii, N., Ishida, Y., Ohgushi, M., Takahashi, J., Eiraku, M. and Sasai, Y. (2015). Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue. Nat. Commun. 6, 8896.
    • (2015) Nat. Commun , vol.6 , pp. 8896
    • Sakaguchi, H.1    Kadoshima, T.2    Soen, M.3    Narii, N.4    Ishida, Y.5    Ohgushi, M.6    Takahashi, J.7    Eiraku, M.8    Sasai, Y.9
  • 35
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K. and Yamanaka, S. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 37
    • 84954369157 scopus 로고    scopus 로고
    • Zika virus in Brazil and macular atrophy in a child with microcephaly
    • Ventura, C. V., Maia, M., Bravo-Filho, V., Gois, A. L. and Belfort, R., Jr.. (2016). Zika virus in Brazil and macular atrophy in a child with microcephaly. Lancet 387, 228.
    • (2016) Lancet , vol.387 , pp. 228
    • Ventura, C.V.1    Maia, M.2    Bravo-Filho, V.3    Gois, A.L.4    Belfort, R.5
  • 40
    • 84949757589 scopus 로고    scopus 로고
    • Modeling psychiatric disorders with patient-derived iPSCs
    • Wen, Z., Christian, K. M., Song, H. and Ming, G.-l. (2016). Modeling psychiatric disorders with patient-derived iPSCs. Curr. Opin. Neurobiol. 36, 118-127.
    • (2016) Curr. Opin. Neurobiol , vol.36 , pp. 118-127
    • Wen, Z.1    Christian, K.M.2    Song, H.3    Ming, G.-L.4
  • 41
    • 84984662505 scopus 로고    scopus 로고
    • Identification of smallmolecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
    • Xu, M., Lee, E. M., Wen, Z., Cheng, Y., Huang, W.-K., Qian, X., Tcw, J., Kouznetsova, J., Ogden, S. C., Hammack, C. et al. (2016). Identification of smallmolecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen. Nat. Med. 22, 1101-1107.
    • (2016) Nat. Med , vol.22 , pp. 1101-1107
    • Xu, M.1    Lee, E.M.2    Wen, Z.3    Cheng, Y.4    Huang, W.-K.5    Qian, X.6    Tcw, J.7    Kouznetsova, J.8    Ogden, S.C.9    Hammack, C.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.