Enterohemorrhagic Escherichia coli Reduces Mucus and Intermicrovillar Bridges in Human Stem Cell-Derived Colonoids

Cellular and Molecular Gastroenterology and Hepatology

Volumn 2, Issue 1, 2016, Pages 48-62.e3

  In, Julie ^a   Foulke Abel, Jennifer ^a   Zachos, Nicholas C ^a   Hansen, Anne Marie ^b   Kaper, James B ^b   Bernstein, Harris D ^c   Halushka, Marc ^a   Blutt, Sarah ^d   Estes, Mary K ^d   Donowitz, Mark ^a   Kovbasnjuk, Olga ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Human Colonoid Monolayers; Intestinal Organoids; Microvillar Effacement; Serine Protease EspP

Indexed keywords

CADHERIN; MUCIN 2; OCCLUDIN; PROTEIN ESPP; PROTOCADHERIN 24; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ADULT; APICAL MEMBRANE; ARTICLE; BACTERIAL COLONIZATION; BRUSH BORDER; CELL DAMAGE; CELL DIFFERENTIATION; COLON MUCOSA; CONTROLLED STUDY; ELECTRIC RESISTANCE; ENTEROHEMORRHAGIC ESCHERICHIA COLI; ENTEROHEMORRHAGIC ESCHERICHIA COLI INFECTION; EPITHELIUM CELL; ESCHERICHIA COLI INFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE VILLUS; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPY; STEM CELL; TIGHT JUNCTION; TRANSMISSION ELECTRON MICROSCOPY;

EID: 84951296372     PISSN: None     EISSN: 2352345X     Source Type: Journal    
DOI: 10.1016/j.jcmgh.2015.10.001     Document Type: Article

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