Modeling rotavirus infection and antiviral therapy using primary intestinal organoids

Antiviral Research

Volumn 123, Issue , 2015, Pages 120-131

  Yin, Yuebang ^a   Bijvelds, Marcel ^a   Dang, Wen ^a   Xu, Lei ^a   Van Der Eijk, Annemiek A ^a   Knipping, Karen ^b   Tuysuz, Nesrin ^a   Dekkers, Johanna F ^c   Wang, Yijin ^a   De Jonge, Jeroen ^a   Sprengers, Dave ^a   Van Der Laan, Luc J W ^a   Beekman, Jeffrey M ^c   Ten Berge, Derk ^a   Metselaar, Herold J ^a   De Jonge, Hugo ^a   Koopmans, Marion P G ^a   Peppelenbosch, Maikel P ^a   Pan, Qiuwei ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b Nutricia Nederland   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Interferon; Intestinal organoids; Ribavirin; Rotavirus

Indexed keywords

ALPHA INTERFERON; GENOMIC RNA; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; RIBAVIRIN; VIRUS PROTEIN; VIRUS RNA; ANTIVIRUS AGENT;

ADULT; AGED; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ANTIVIRAL THERAPY; ARTICLE; CACO 2 CELL LINE; CHILD; COLON BIOPSY; CONTROLLED STUDY; CYTOPLASM; DRUG EFFICACY; FEMALE; GENE DOSAGE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFECTION SENSITIVITY; INTESTINAL TISSUE; MALE; MOUSE; NONHUMAN; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; ROTAVIRUS; ROTAVIRUS INFECTION; TREATMENT RESPONSE; VIRUS REPLICATION; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECTS; INFANT; INTESTINE; PATHOLOGY; PHYSIOLOGY; ROTAVIRUS INFECTIONS; VIROLOGY;

ADULT; AGED; ANIMALS; ANTIVIRAL AGENTS; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INTERFERON-ALPHA; INTESTINES; MALE; MICE; MODELS, BIOLOGICAL; ORGANOIDS; RIBAVIRIN; ROTAVIRUS; ROTAVIRUS INFECTIONS; VIRUS REPLICATION;

EID: 84942784008     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2015.09.010     Document Type: Article

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