The relevance of genomic signatures at adhesion GPCR loci in humans

Handbook of Experimental Pharmacology

Volumn 234, Issue , 2016, Pages 179-217

  Kovacs, Peter ^a   Schöneberg, Torsten ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Adhesion G protein coupled receptors; Disease; Genome wide association studies; Mutation; Natural selection; Population genetics

Indexed keywords

ADHESION G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR; UNCLASSIFIED DRUG; PROTEIN BINDING; TRANSCRIPTOME;

ADAPTATION; AGPCR GENE; EVOLUTION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC SELECTION; GENETIC VARIATION; GENOMICS; GENOTYPE PHENOTYPE CORRELATION; HUMAN; MONOGENIC DISORDER; NONHUMAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; BINDING SITE; CELL ADHESION; CELL MEMBRANE; CHEMISTRY; DNA MUTATIONAL ANALYSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; METABOLISM; MOLECULAR EVOLUTION; MUTATION; PHENOTYPE; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CELL ADHESION; CELL MEMBRANE; DNA MUTATIONAL ANALYSIS; EVOLUTION, MOLECULAR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; HUMANS; MUTATION; PHENOTYPE; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; QUANTITATIVE TRAIT LOCI; RECEPTORS, G-PROTEIN-COUPLED; SELECTION, GENETIC; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTOME;

EID: 84995480120     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/978-3-319-41523-9_9     Document Type: Chapter

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