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Volumn 437, Issue 7062, 2005, Pages 1153-1157

Natural selection on protein-coding genes in the human genome

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DNA; MUTAGENS; PROTEINS;

EID: 27144539145     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04240     Document Type: Article
Times cited : (626)

References (24)
  • 2
    • 0023339852 scopus 로고
    • A test of neutral molecular evolution based on nucleotide data
    • Hudson, R. R., Kreitman, M. & Aguadé, M. A test of neutral molecular evolution based on nucleotide data. Genetics 116, 153-159 (1987).
    • (1987) Genetics , vol.116 , pp. 153-159
    • Hudson, R.R.1    Kreitman, M.2    Aguadé, M.3
  • 3
    • 0026428610 scopus 로고
    • Adaptive protein evolution at the Adh locus in Drosophila
    • McDonald, J. H. & Kreitman, M. Adaptive protein evolution at the Adh locus in Drosophila. Nature 351, 652-654 (1991).
    • (1991) Nature , vol.351 , pp. 652-654
    • McDonald, J.H.1    Kreitman, M.2
  • 4
    • 0026460082 scopus 로고
    • Population genetics of polymorphism and divergence
    • Sawyer, S. A. & Hartl, D. L. Population genetics of polymorphism and divergence. Genetics 132, 1161-1176 (1992).
    • (1992) Genetics , vol.132 , pp. 1161-1176
    • Sawyer, S.A.1    Hartl, D.L.2
  • 5
    • 0033611501 scopus 로고    scopus 로고
    • High genomic deleterious mutation rates in hominids
    • Eyre-Walker, A. & Keightley, P. D. High genomic deleterious mutation rates in hominids. Nature 397, 344-347 (1999).
    • (1999) Nature , vol.397 , pp. 344-347
    • Eyre-Walker, A.1    Keightley, P.D.2
  • 6
    • 0037186608 scopus 로고    scopus 로고
    • Testing the neutral theory of molecular evolution with genomic data from Drosophila
    • Fay, J. C., Wyckoff, G. J. & Wu, C. I. Testing the neutral theory of molecular evolution with genomic data from Drosophila. Nature 415, 1024-1026 (2002).
    • (2002) Nature , vol.415 , pp. 1024-1026
    • Fay, J.C.1    Wyckoff, G.J.2    Wu, C.I.3
  • 7
    • 0347380978 scopus 로고    scopus 로고
    • Bayesian analysis suggests that most amino acid replacements in Drosophila are driven by positive selection
    • Sawyer, S. A., Kulathinal, R. J., Bustamante, C. D. & Hartl, D. L. Bayesian analysis suggests that most amino acid replacements in Drosophila are driven by positive selection. J. Mol. Evol. 57 (suppl. 1), S154-S164 (2003).
    • (2003) J. Mol. Evol. , vol.57 , Issue.1 SUPPL.
    • Sawyer, S.A.1    Kulathinal, R.J.2    Bustamante, C.D.3    Hartl, D.L.4
  • 8
    • 0037186564 scopus 로고    scopus 로고
    • Adaptive protein evolution in Drosophila
    • Smith, N. G. & Eyre-Walker, A. Adaptive protein evolution in Drosophila. Nature 415, 1022-1024 (2002).
    • (2002) Nature , vol.415 , pp. 1022-1024
    • Smith, N.G.1    Eyre-Walker, A.2
  • 9
    • 0037041421 scopus 로고    scopus 로고
    • The cost of inbreeding in Arabidopsis
    • Bustamante, C. D. et al. The cost of inbreeding in Arabidopsis. Nature 416, 531-534 (2002).
    • (2002) Nature , vol.416 , pp. 531-534
    • Bustamante, C.D.1
  • 10
    • 22744434580 scopus 로고    scopus 로고
    • The pattern of polymorphism in Arabidopsis thaliana
    • Nordborg, M. et al. The pattern of polymorphism in Arabidopsis thaliana. PLoS Biol. 3, e196 (2005).
    • (2005) PLoS Biol. , vol.3
    • Nordborg, M.1
  • 11
    • 0032990407 scopus 로고    scopus 로고
    • Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis
    • Halushka, M. K. et al. Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nature Genet. 22, 239-247 (1999).
    • (1999) Nature Genet. , vol.22 , pp. 239-247
    • Halushka, M.K.1
  • 12
    • 0032991552 scopus 로고    scopus 로고
    • Characterization of single-nucleotide polymorphisms in coding regions of human genes
    • Cargill, M. et al. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nature Genet. 22, 231-238 (1999).
    • (1999) Nature Genet. , vol.22 , pp. 231-238
    • Cargill, M.1
  • 13
    • 0035919656 scopus 로고    scopus 로고
    • Haplotype variation and linkage disequilibrium in 313 human genes
    • Stephens, J. C. et al. Haplotype variation and linkage disequilibrium in 313 human genes. Science 293, 489-493 (2001).
    • (2001) Science , vol.293 , pp. 489-493
    • Stephens, J.C.1
  • 14
    • 6344267228 scopus 로고    scopus 로고
    • Pattern of sequence variation across 213 environmental response genes
    • Livingston, R. J. et al. Pattern of sequence variation across 213 environmental response genes. Genome Res. 14, 1821-1831 (2004).
    • (2004) Genome Res. , vol.14 , pp. 1821-1831
    • Livingston, R.J.1
  • 15
    • 0035869223 scopus 로고    scopus 로고
    • Prediction of deleterious human alleles
    • Sunyaev, S. et al. Prediction of deleterious human alleles. Hum. Mol. Genet. 10, 591-597 (2001).
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 591-597
    • Sunyaev, S.1
  • 16
    • 20344380699 scopus 로고    scopus 로고
    • Simultaneous inference of selection and population growth from patterns of variation in the human genome
    • Williamson, S. et al. Simultaneous inference of selection and population growth from patterns of variation in the human genome. Proc. Natl Acad. Sci. USA 102, 7882-7887 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 7882-7887
    • Williamson, S.1
  • 17
    • 0037296452 scopus 로고    scopus 로고
    • Selection on rapidly evolving proteins in the Arabidopsis genome
    • Barrier, M., Bustamante, C. D., Yu, J. & Purugganan, M. D. Selection on rapidly evolving proteins in the Arabidopsis genome. Genetics 163, 723-733 (2003).
    • (2003) Genetics , vol.163 , pp. 723-733
    • Barrier, M.1    Bustamante, C.D.2    Yu, J.3    Purugganan, M.D.4
  • 18
    • 20444430245 scopus 로고    scopus 로고
    • A scan for positively selected genes in the genomes of humans and chimpanzees
    • Nielsen, R. et al. A scan for positively selected genes in the genomes of humans and chimpanzees. PLoS Biol. 6, e170 (2005).
    • (2005) PLoS Biol. , vol.6
    • Nielsen, R.1
  • 19
    • 7144223404 scopus 로고    scopus 로고
    • Alpha-adducin polymorphisms and renal sodium handling in essential hypertensive patients
    • Manunta, P. et al. Alpha-adducin polymorphisms and renal sodium handling in essential hypertensive patients. Kidney Int. 53, 1471-1478 (1998).
    • (1998) Kidney Int. , vol.53 , pp. 1471-1478
    • Manunta, P.1
  • 20
    • 0036281144 scopus 로고    scopus 로고
    • ADD1 460W allele associated with cardiovascular disease in hypertensive individuals
    • Morrison, A. C., Bray, M. S., Folsom, A. R. & Boerwinkle, E. ADD1 460W allele associated with cardiovascular disease in hypertensive individuals. Hypertension 39, 1053-1057 (2002).
    • (2002) Hypertension , vol.39 , pp. 1053-1057
    • Morrison, A.C.1    Bray, M.S.2    Folsom, A.R.3    Boerwinkle, E.4
  • 21
    • 0036226603 scopus 로고    scopus 로고
    • BLAT-the BLAST-like alignment tool
    • Kent, W. J. BLAT-the BLAST-like alignment tool. Genome Res. 12, 656-664 (2002).
    • (2002) Genome Res. , vol.12 , pp. 656-664
    • Kent, W.J.1
  • 22
    • 0033824906 scopus 로고    scopus 로고
    • Contrasting patterns of nonneutral evolution in proteins encoded in nuclear and mitochondrial genomes
    • Weinreich, D. M. & Rand, D. M. Contrasting patterns of nonneutral evolution in proteins encoded in nuclear and mitochondrial genomes. Genetics 156, 385-399 (2000).
    • (2000) Genetics , vol.156 , pp. 385-399
    • Weinreich, D.M.1    Rand, D.M.2
  • 23
    • 5144231907 scopus 로고    scopus 로고
    • Population genetics of polymorphism and divergence for diploid selection models with arbitrary dominance
    • Williamson, S., Fledel-Alon, A. & Bustamante, C. D. Population genetics of polymorphism and divergence for diploid selection models with arbitrary dominance. Genetics 168, 463-475 (2004).
    • (2004) Genetics , vol.168 , pp. 463-475
    • Williamson, S.1    Fledel-Alon, A.2    Bustamante, C.D.3
  • 24
    • 0025599435 scopus 로고
    • Polymorphism at the self-incompatibility locus in Solanaceae predates speciation
    • Ioerger, T. R., Clark, A. G. & Kao, T. H. Polymorphism at the self-incompatibility locus in Solanaceae predates speciation. Proc. Natl Acad. Sci. USA 87, 9732-9735 (1990).
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 9732-9735
    • Ioerger, T.R.1    Clark, A.G.2    Kao, T.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.