Mutational Signatures of De-Differentiation in Functional Non-Coding Regions of Melanoma Genomes

PLoS Genetics

Volumn 8, Issue 8, 2012, Pages

  Parker, Stephen C J ^a   Gartner, Jared ^a   Cardenas Navia, Isabel ^a   Wei, Xiaomu ^a   Ozel Abaan, Hatice ^a   Ajay, Subramanian S ^a,g   Hansen, Nancy F ^a   Song, Lingyun ^b   Bhanot, Umesh K ^c   Killian, J Keith ^d   Gindin, Yevgeniy ^d,e   Walker, Robert L ^d   Meltzer, Paul S ^d   Mullikin, James C ^a   Furey, Terrence S ^f   Crawford, Gregory E ^b   Rosenberg, Steven A ^d   Samuels, Yardena ^a   Margulies, Elliott H ^a,g  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b DUKE UNIVERSITY   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e BOSTON UNIVERSITY   (United States)

^f UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^g Illumina Cambridge   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FOCAL ADHESION KINASE 2;

A DISINTEGRIN AND METALLOPROTEINASE 29 GENE; ADULT; ARTICLE; CARCINOGENESIS; CASE REPORT; CELL DEDIFFERENTIATION; CELL SPECIFICITY; CELL TYPE; CONTROLLED STUDY; COPY NUMBER VARIATION; GENE; GENE FUNCTION; GENE IDENTIFICATION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC VARIABILITY; GENOME ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; METASTATIC MELANOMA; MISSENSE MUTATION; MUTATIONAL ANALYSIS; PROTEIN TYROSINE KINASE 2B GENE; SOMATIC MUTATION; SOMATIC SINGLE NUCLEOTIDE VARIANT; TISSUE SPECIFICITY;

ADULT; CELL DEDIFFERENTIATION; DNA COPY NUMBER VARIATIONS; DNA, INTERGENIC; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MELANOCYTES; MELANOMA; NEOPLASM METASTASIS; POLYMORPHISM, SINGLE NUCLEOTIDE; PRIMARY CELL CULTURE; REGULATORY SEQUENCES, NUCLEIC ACID; TUMOR CELLS, CULTURED;

EID: 84866150950     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002871     Document Type: Article

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