Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

American Journal of Respiratory and Critical Care Medicine

Volumn 186, Issue 7, 2012, Pages 622-632

  Wilk, Jemma B ^a,b   Shrine, Nick R G ^c   Loehr, Laura R ^d   Zhao, Jing Hua ^e   Manichaikul, Ani ^f,g   Lopez, Lorna M ^h   Smith, Albert Vernon ^i,j   Heckbert, Susan R ^k,l   Smolonska, Joanna ^m   Tang, Wenbo ⁿ   Loth, Daan W ^o,p   Curjuric, Ivan ^q,r   Hui, Jennie ^s,t,u   Cho, Michael H ^a   Latourelle, Jeanne C ^v   Henry, Amanda P ^w   Aldrich, Melinda ^x   Bakke, Per ^y   Beaty, Terri H ^z   Bentley, Amy R ^aa   Borecki, Ingrid B ^ab   Brusselle, Guy G ^ac   Burkart, Kristin M ^ad   Chen, Ting Hsu ^v,ae   Couper, David ^d   Crapo, James D ^af   Davies, Gail ^h   Dupuis, Josée ^b,ag   Franceschini, Nora ^d   Gulsvik, Amund ^y   Hancock, Dana B ^ah,ai   Harris, Tamara B ^aj   Hofman, Albert ^o,ak   Imboden, Medea ^q,r   James, Alan L ^s,al   Khaw, Kay Tee ^am   Lahousse, Lies ^o,ac   Launer, Lenore J ^aj   Litonjua, Augusto ^a   Liu, Yongmei ^an   Lohman, Kurt K ^an   Lomas, David A ^ao   Lumley, Thomas ^ap   Marciante, Kristin D ^k   McArdle, Wendy L ^aq   Meibohm, Bernd ^ar   Morrison, Alanna C ^as   Musk, Arthur W ^s,u,al   Myers, Richard H ^v   North, Kari E ^d   Postma, Dirkje S ^m   Psaty, Bruce M ^k,l,at   Rich, Stephen S ^f   Rivadeneira, Fernando ^o,ak   Rochat, Thierry ^au   Rotter, Jerome I ^av   Soler Artigas, María ^c   Starr, John M ^h   Uitterlinden, André G ^o,ak   Wareham, Nicholas J ^e   Wijmenga, Cisca ^m   Zanen, Pieter ^aw   Province, Michael A ^ab   Silverman, Edwin K ^a   Deary, Ian J ^h   Palmer, Lyle J ^ax,ay   Cassano, Patricia A ^n,az   Gudnason, Vilmundur ^i,j   Barr, R Graham ^ad,ba   Loos, Ruth J F ^e   Strachan, David P ^bb   London, Stephanie J ^ah   Boezen, H Marike ^m   Probst Hensch, Nicole ^q,r   Gharib, Sina A ^l   Hall, Ian P ^w   O'Connor, George T ^b,v   Tobin, Martin D ^c   Stricker, Bruno H ^o,p,ak   more..

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b FRAMINGHAM HEART STUDY   (United States)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

^d University of North Carolina at Chapel Hill   (United States)

^e ADDENBROOKE S HOSPITAL   (United Kingdom)

^f UNIVERSITY OF VIRGINIA   (United States)

^g UNIVERSITY OF VIRGINIA   (United States)

^h UNIVERSITY OF EDINBURGH   (United Kingdom)

ⁱ ICELANDIC HEART ASSOCIATION   (Iceland)

^j UNIVERSITY OF ICELAND   (Iceland)

^k UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^l UNIVERSITY OF WASHINGTON   (United States)

^m UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

ⁿ Inspectorate of Healthcare ^*  (United States)

^o ERASMUS MEDICAL CENTER   (Netherlands)

^p Inspectorate of Health Care   (Netherlands)

^q SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^r UNIVERSITY OF BASEL   (Switzerland)

^s SIR CHARLES GAIRDNER HOSPITAL   (Australia)

^t PATHWEST LABORATORY MEDICINE   (Australia)

^u UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^v BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^w UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^x VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^y HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^z JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^aa NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^ab WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^ac GHENT UNIVERSITY HOSPITAL   (Belgium)

^ad New York Presbyterian Columbia University Medical Center   (United States)

^ae VA BOSTON HEALTHCARE SYSTEM   (United States)

^af DEPARTMENT OF MEDICINE   (United States)

^ag BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^ah NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^ai RTI INTERNATIONAL   (United States)

^aj NATIONAL INSTITUTE ON AGING   (United States)

^ak Netherlands Genomics Initiative   (Netherlands)

^al UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^am UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^an WAKE FOREST SCHOOL OF MEDICINE   (United States)

^ao UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^ap UNIVERSITY OF AUCKLAND   (New Zealand)

^aq UNIVERSITY OF BRISTOL   (United Kingdom)

^ar UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^as UNIVERSITY OF TEXAS   (United States)

^at CENTER FOR HEALTH STUDIES   (United States)

^au GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^av CEDARS SINAI MEDICAL CENTER   (United States)

^aw UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^ax ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

^ay MOUNT SINAI HOSPITAL   (Canada)

^az WEILL CORNELL MEDICAL COLLEGE   (United States)

^ba Department of Medicine   (United States)

^bb ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

more..

Author keywords

Chronic obstructive pulmonary disease; Genes; Single nucleotide polymorphism

Indexed keywords

ADAM19 PROTEIN; ADAMTS19 PROTEIN; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA 3; NICOTINIC RECEPTOR ALPHA 5; PPAP2B PROTEIN; PROTEIN; RARB PROTEIN; UNCLASSIFIED DRUG;

AIRWAY OBSTRUCTION; ARTICLE; BRONCHUS MUCOSA; BRONCHUS MUSCLE; CHROMOSOME 15Q; EPITHELIUM CELL; FAMILY STUDY; FOLLOW UP; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; GENE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC RISK; HTR4 GENE; HUMAN; LUNG; MAJOR CLINICAL STUDY; META ANALYSIS; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING HABIT;

AGED; FEMALE; FORCED EXPIRATORY VOLUME; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MIDDLE AGED; NERVE TISSUE PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECEPTORS, NICOTINIC; RECEPTORS, SEROTONIN, 5-HT4; SMOKING; VITAL CAPACITY;

EID: 84867130207     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201202-0366OC     Document Type: Article

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