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Volumn 8, Issue 12, 2012, Pages

Chapter 11: Genome-Wide Association Studies

Author keywords

[No Author keywords available]

Indexed keywords

CHAPTER 11; COMMON DISEASE; GENETIC ARCHITECTURE; GENETIC INFORMATION; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDIES; HUMAN DISEASE; HUMAN GENETICS; LOOK-FORWARD; STUDY DESIGN;

EID: 84872040426     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002822     Document Type: Article
Times cited : (881)

References (55)
  • 1
    • 20244388812 scopus 로고    scopus 로고
    • Complement factor H variant increases the risk of age-related macular degeneration
    • doi:10.1126/science.1110359
    • Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, et al. (2005) Complement factor H variant increases the risk of age-related macular degeneration. Science 308: 419-421 doi: 10.1126/science.1110359.
    • (2005) Science , vol.308 , pp. 419-421
    • Haines, J.L.1    Hauser, M.A.2    Schmidt, S.3    Scott, W.K.4    Olson, L.M.5
  • 2
    • 17244379811 scopus 로고    scopus 로고
    • Complement factor H polymorphism and age-related macular degeneration
    • doi:10.1126/science.1110189
    • Edwards AO, Ritter R III, Abel KJ, Manning A, Panhuysen C, et al. (2005) Complement factor H polymorphism and age-related macular degeneration. Science 308: 421-424 doi: 10.1126/science.1110189.
    • (2005) Science , vol.308 , pp. 421-424
    • Edwards, A.O.1    Ritter III, R.2    Abel, K.J.3    Manning, A.4    Panhuysen, C.5
  • 3
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • doi:10.1126/science.1109557
    • Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, et al. (2005) Complement factor H polymorphism in age-related macular degeneration. Science 308: 385-389 doi: 10.1126/science.1109557.
    • (2005) Science , vol.308 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3    Tsai, J.Y.4    Sackler, R.S.5
  • 4
    • 51649110496 scopus 로고    scopus 로고
    • A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose
    • doi:10.1182/blood-2008-01-134247
    • Cooper GM, Johnson JA, Langaee TY, Feng H, Stanaway IB, et al. (2008) A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose. Blood 112: 1022-1027 doi: 10.1182/blood-2008-01-134247.
    • (2008) Blood , vol.112 , pp. 1022-1027
    • Cooper, G.M.1    Johnson, J.A.2    Langaee, T.Y.3    Feng, H.4    Stanaway, I.B.5
  • 5
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • Genomes Project Consortium, doi:10.1038/nature09534
    • Genomes Project Consortium (2010) A map of human genome variation from population-scale sequencing. Nature 467: 1061-1073 doi: 10.1038/nature09534.
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 6
    • 38549087902 scopus 로고    scopus 로고
    • ORegAnno: an open-access community-driven resource for regulatory annotation
    • doi:10.1093/nar/gkm967
    • Griffith OL, Montgomery SB, Bernier B, Chu B, Kasaian K, et al. (2008) ORegAnno: an open-access community-driven resource for regulatory annotation. Nucleic Acids Res 36: D107-D113 doi: 10.1093/nar/gkm967.
    • (2008) Nucleic Acids Res , vol.36
    • Griffith, O.L.1    Montgomery, S.B.2    Bernier, B.3    Chu, B.4    Kasaian, K.5
  • 7
    • 77956331627 scopus 로고    scopus 로고
    • Integrating common and rare genetic variation in diverse human populations
    • doi:10.1038/nature09298
    • Altshuler DM, Gibbs RA, Peltonen L, Altshuler DM, Gibbs RA, et al. (2010) Integrating common and rare genetic variation in diverse human populations. Nature 467: 52-58 doi: 10.1038/nature09298.
    • (2010) Nature , vol.467 , pp. 52-58
    • Altshuler, D.M.1    Gibbs, R.A.2    Peltonen, L.3    Altshuler, D.M.4    Gibbs, R.A.5
  • 8
    • 0024423668 scopus 로고
    • Identification of the cystic fibrosis gene: genetic analysis
    • Kerem B, Rommens JM, Buchanan JA, Markiewicz D, et al. (1989) Identification of the cystic fibrosis gene: genetic analysis. Science 245: 1073-1080.
    • (1989) Science , vol.245 , pp. 1073-1080
    • Kerem, B.1    Rommens, J.M.2    Buchanan, J.A.3    Markiewicz, D.4
  • 9
    • 0026864956 scopus 로고
    • The Huntington's disease candidate region exhibits many different haplotypes
    • doi:10.1038/ng0592-99
    • MacDonald ME, Novelletto A, Lin C, Tagle D, Barnes G, et al. (1992) The Huntington's disease candidate region exhibits many different haplotypes. Nat Genet 1: 99-103 doi: 10.1038/ng0592-99.
    • (1992) Nat Genet , vol.1 , pp. 99-103
    • MacDonald, M.E.1    Novelletto, A.2    Lin, C.3    Tagle, D.4    Barnes, G.5
  • 10
    • 13144306071 scopus 로고    scopus 로고
    • Genome-wide association studies for common diseases and complex traits
    • doi:10.1038/nrg1521
    • Hirschhorn JN, Daly MJ, (2005) Genome-wide association studies for common diseases and complex traits. Nat Rev Genet 6: 95-108 doi: 10.1038/nrg1521.
    • (2005) Nat Rev Genet , vol.6 , pp. 95-108
    • Hirschhorn, J.N.1    Daly, M.J.2
  • 11
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
    • Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, et al. (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261: 921-923.
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3    Schmechel, D.E.4    Gaskell, P.C.5
  • 12
    • 0033624575 scopus 로고    scopus 로고
    • The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • doi:10.1038/79216
    • Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, et al. (2000) The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26: 76-80 doi: 10.1038/79216.
    • (2000) Nat Genet , vol.26 , pp. 76-80
    • Altshuler, D.1    Hirschhorn, J.N.2    Klannemark, M.3    Lindgren, C.M.4    Vohl, M.C.5
  • 13
    • 0035451780 scopus 로고    scopus 로고
    • On the allelic spectrum of human disease
    • Reich DE, Lander ES, (2001) On the allelic spectrum of human disease. Trends Genet 17: 502-510.
    • (2001) Trends Genet , vol.17 , pp. 502-510
    • Reich, D.E.1    Lander, E.S.2
  • 14
    • 67249117049 scopus 로고    scopus 로고
    • Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
    • doi:10.1073/pnas.0903103106
    • Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, et al. (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A 106: 9362-9367 doi: 10.1073/pnas.0903103106.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9362-9367
    • Hindorff, L.A.1    Sethupathy, P.2    Junkins, H.A.3    Ramos, E.M.4    Mehta, J.P.5
  • 15
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • International HapMap Consortium, doi:10.1038/nature04226
    • International HapMap Consortium (2005) A haplotype map of the human genome. Nature 437: 1299-1320 doi: 10.1038/nature04226.
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 16
    • 77950338000 scopus 로고    scopus 로고
    • Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record
    • doi:10.1016/j.ajhg.2010.03.003
    • Ritchie MD, Denny JC, Crawford DC, Ramirez AH, Weiner JB, et al. (2010) Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record. Am J Hum Genet 86: 560-572 doi: 10.1016/j.ajhg.2010.03.003.
    • (2010) Am J Hum Genet , vol.86 , pp. 560-572
    • Ritchie, M.D.1    Denny, J.C.2    Crawford, D.C.3    Ramirez, A.H.4    Weiner, J.B.5
  • 17
    • 0029150074 scopus 로고
    • A comparison of linkage disequilibrium measures for fine-scale mapping
    • doi:10.1006/geno.1995.9003
    • Devlin B, Risch N, (1995) A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics 29: 311-322 doi: 10.1006/geno.1995.9003.
    • (1995) Genomics , vol.29 , pp. 311-322
    • Devlin, B.1    Risch, N.2
  • 18
    • 0033794938 scopus 로고    scopus 로고
    • Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data
    • doi:10.1086/303069
    • Fallin D, Schork NJ, (2000) Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data. Am J Hum Genet 67: 947-959 doi: 10.1086/303069.
    • (2000) Am J Hum Genet , vol.67 , pp. 947-959
    • Fallin, D.1    Schork, N.J.2
  • 19
    • 42649111672 scopus 로고    scopus 로고
    • Evaluation of coverage variation of SNP chips for genome-wide association studies
    • doi:10.1038/sj.ejhg.5202007
    • Li M, Li C, Guan W, (2008) Evaluation of coverage variation of SNP chips for genome-wide association studies. Eur J Hum Genet 16: 635-643 doi: 10.1038/sj.ejhg.5202007.
    • (2008) Eur J Hum Genet , vol.16 , pp. 635-643
    • Li, M.1    Li, C.2    Guan, W.3
  • 20
    • 79955670705 scopus 로고    scopus 로고
    • Technological issues and experimental design of gene association studies
    • doi:10.1007/978-1-61737-954-3_1
    • Distefano JK, Taverna DM, (2011) Technological issues and experimental design of gene association studies. Methods Mol Biol 700: 3-16 doi: 10.1007/978-1-61737-954-3_1.
    • (2011) Methods Mol Biol , vol.700 , pp. 3-16
    • Distefano, J.K.1    Taverna, D.M.2
  • 21
    • 77955505564 scopus 로고    scopus 로고
    • Biological, clinical and population relevance of 95 loci for blood lipids
    • doi:10.1038/nature09270
    • Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, et al. (2010) Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466: 707-713 doi: 10.1038/nature09270.
    • (2010) Nature , vol.466 , pp. 707-713
    • Teslovich, T.M.1    Musunuru, K.2    Smith, A.V.3    Edmondson, A.C.4    Stylianou, I.M.5
  • 22
    • 79952995197 scopus 로고    scopus 로고
    • Genes associated with multiple sclerosis: 15 and counting
    • doi:10.1586/erm.10.77
    • Habek M, Brinar VV, Borovecki F, (2010) Genes associated with multiple sclerosis: 15 and counting. Expert Rev Mol Diagn 10: 857-861 doi: 10.1586/erm.10.77.
    • (2010) Expert Rev Mol Diagn , vol.10 , pp. 857-861
    • Habek, M.1    Brinar, V.V.2    Borovecki, F.3
  • 23
    • 28544436950 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria"
    • doi:10.1002/ana.20703
    • Polman CH, Reingold SC, Edan G, Filippi M, Hartung HP, et al. (2005) Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol 58: 840-846 doi: 10.1002/ana.20703.
    • (2005) Ann Neurol , vol.58 , pp. 840-846
    • Polman, C.H.1    Reingold, S.C.2    Edan, G.3    Filippi, M.4    Hartung, H.P.5
  • 24
    • 78049235519 scopus 로고    scopus 로고
    • Evaluation of the age-related eye disease study clinical lens grading system AREDS report No. 31
    • doi:10.1016/j.ophtha.2010.02.033
    • Chew EY, Kim J, Sperduto RD, Datiles MB III, Coleman HR, et al. (2010) Evaluation of the age-related eye disease study clinical lens grading system AREDS report No. 31. Ophthalmology 117: 2112-2119 doi: 10.1016/j.ophtha.2010.02.033.
    • (2010) Ophthalmology , vol.117 , pp. 2112-2119
    • Chew, E.Y.1    Kim, J.2    Sperduto, R.D.3    Datiles III, M.B.4    Coleman, H.R.5
  • 25
    • 78549244038 scopus 로고    scopus 로고
    • Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science
    • doi:10.1161/CIRCULATIONAHA.110.948828
    • Denny JC, Ritchie MD, Crawford DC, Schildcrout JS, Ramirez AH, et al. (2010) Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science. Circulation 122: 2016-2021 doi: 10.1161/CIRCULATIONAHA.110.948828.
    • (2010) Circulation , vol.122 , pp. 2016-2021
    • Denny, J.C.1    Ritchie, M.D.2    Crawford, D.C.3    Schildcrout, J.S.4    Ramirez, A.H.5
  • 26
    • 77952025317 scopus 로고    scopus 로고
    • Quantification of the clinical modifiers impacting high-density lipoprotein cholesterol in the community: Personalized Medicine Research Project
    • doi:10.1111/j.1751-7141.2009.00055.x
    • Wilke RA, Berg RL, Linneman JG, Peissig P, Starren J, et al. (2010) Quantification of the clinical modifiers impacting high-density lipoprotein cholesterol in the community: Personalized Medicine Research Project. Prev Cardiol 13: 63-68 doi: 10.1111/j.1751-7141.2009.00055.x.
    • (2010) Prev Cardiol , vol.13 , pp. 63-68
    • Wilke, R.A.1    Berg, R.L.2    Linneman, J.G.3    Peissig, P.4    Starren, J.5
  • 27
    • 77958597919 scopus 로고    scopus 로고
    • Leveraging informatics for genetic studies: use of the electronic medical record to enable a genome-wide association study of peripheral arterial disease
    • doi:10.1136/jamia.2010.004366
    • Kullo IJ, Fan J, Pathak J, Savova GK, Ali Z, et al. (2010) Leveraging informatics for genetic studies: use of the electronic medical record to enable a genome-wide association study of peripheral arterial disease. J Am Med Inform Assoc 17: 568-574 doi: 10.1136/jamia.2010.004366.
    • (2010) J Am Med Inform Assoc , vol.17 , pp. 568-574
    • Kullo, I.J.1    Fan, J.2    Pathak, J.3    Savova, G.K.4    Ali, Z.5
  • 28
    • 77951541774 scopus 로고    scopus 로고
    • Biobanking and pharmacogenomics
    • doi:10.2217/pgs.10.13
    • McCarty CA, Wilke RA, (2010) Biobanking and pharmacogenomics. Pharmacogenomics 11: 637-641 doi: 10.2217/pgs.10.13.
    • (2010) Pharmacogenomics , vol.11 , pp. 637-641
    • McCarty, C.A.1    Wilke, R.A.2
  • 29
    • 0036597746 scopus 로고    scopus 로고
    • Genetic association studies: design, analysis and interpretation
    • Lewis CM, (2002) Genetic association studies: design, analysis and interpretation. Brief Bioinform 3: 146-153.
    • (2002) Brief Bioinform , vol.3 , pp. 146-153
    • Lewis, C.M.1
  • 30
    • 34247340876 scopus 로고    scopus 로고
    • Genetic model testing and statistical power in population-based association studies of quantitative traits
    • doi:10.1002/gepi.20217
    • Lettre G, Lange C, Hirschhorn JN, (2007) Genetic model testing and statistical power in population-based association studies of quantitative traits. Genet Epidemiol 31: 358-362 doi: 10.1002/gepi.20217.
    • (2007) Genet Epidemiol , vol.31 , pp. 358-362
    • Lettre, G.1    Lange, C.2    Hirschhorn, J.N.3
  • 31
    • 0041817568 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies
    • Falush D, Stephens M, Pritchard JK, (2003) Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics 164: 1567-1587.
    • (2003) Genetics , vol.164 , pp. 1567-1587
    • Falush, D.1    Stephens, M.2    Pritchard, J.K.3
  • 32
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • doi:10.1038/ng1847
    • Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, et al. (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38: 904-909 doi: 10.1038/ng1847.
    • (2006) Nat Genet , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5
  • 33
    • 0025066941 scopus 로고
    • More powerful procedures for multiple significance testing
    • Hochberg Y, Benjamini Y, (1990) More powerful procedures for multiple significance testing. Stat Med 9: 811-818.
    • (1990) Stat Med , vol.9 , pp. 811-818
    • Hochberg, Y.1    Benjamini, Y.2
  • 34
    • 46949090611 scopus 로고    scopus 로고
    • Controlling false discoveries in genetic studies
    • doi:10.1002/ajmg.b.30650
    • van den Oord EJ, (2008) Controlling false discoveries in genetic studies. Am J Med Genet B Neuropsychiatr Genet 147B: 637-644 doi: 10.1002/ajmg.b.30650.
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , pp. 637-644
    • van den Oord, E.J.1
  • 35
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: a tool set for whole-genome association and population-based linkage analyses
    • doi:10.1086/519795
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575 doi: 10.1086/519795.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.5
  • 36
    • 48249099690 scopus 로고    scopus 로고
    • PRESTO: rapid calculation of order statistic distributions and multiple-testing adjusted P-values via permutation for one and two-stage genetic association studies
    • doi:10.1186/1471-2105-9-309
    • Browning BL, (2008) PRESTO: rapid calculation of order statistic distributions and multiple-testing adjusted P-values via permutation for one and two-stage genetic association studies. BMC Bioinformatics 9: 309 doi: 10.1186/1471-2105-9-309.
    • (2008) BMC Bioinformatics , vol.9 , pp. 309
    • Browning, B.L.1
  • 37
    • 77955858293 scopus 로고    scopus 로고
    • PERMORY: an LD-exploiting permutation test algorithm for powerful genome-wide association testing
    • doi:10.1093/bioinformatics/btq399
    • Pahl R, Schafer H, (2010) PERMORY: an LD-exploiting permutation test algorithm for powerful genome-wide association testing. Bioinformatics 26: 2093-2100 doi: 10.1093/bioinformatics/btq399.
    • (2010) Bioinformatics , vol.26 , pp. 2093-2100
    • Pahl, R.1    Schafer, H.2
  • 38
    • 42249087793 scopus 로고    scopus 로고
    • Estimation of significance thresholds for genomewide association scans
    • doi:10.1002/gepi.20297
    • Dudbridge F, Gusnanto A, (2008) Estimation of significance thresholds for genomewide association scans. Genet Epidemiol 32: 227-234 doi: 10.1002/gepi.20297.
    • (2008) Genet Epidemiol , vol.32 , pp. 227-234
    • Dudbridge, F.1    Gusnanto, A.2
  • 39
    • 2142705388 scopus 로고    scopus 로고
    • STUDENTJAMA. The challenges of whole-genome approaches to common diseases
    • doi:10.1001/jama.291.13.1642
    • Moore JH, Ritchie MD, (2004) STUDENTJAMA. The challenges of whole-genome approaches to common diseases. JAMA 291: 1642-1643 doi: 10.1001/jama.291.13.1642.
    • (2004) JAMA , vol.291 , pp. 1642-1643
    • Moore, J.H.1    Ritchie, M.D.2
  • 40
    • 84859233860 scopus 로고    scopus 로고
    • Use of biological knowledge to inform the analysis of gene-gene interactions involved in modulating virologic failure with efavirenz-containing treatment regimens in art-naive actg clinical trials participants
    • Grady BJ, Torstenson ES, McLaren PJ, de Bakker PI, Haas DW, et al. (2011) Use of biological knowledge to inform the analysis of gene-gene interactions involved in modulating virologic failure with efavirenz-containing treatment regimens in art-naive actg clinical trials participants. Pac Symp Biocomput pp. 253-264.
    • (2011) Pac Symp Biocomput , pp. 253-264
    • Grady, B.J.1    Torstenson, E.S.2    McLaren, P.J.3    de Bakker, P.I.4    Haas, D.W.5
  • 41
    • 61949417042 scopus 로고    scopus 로고
    • Biofilter: a knowledge-integration system for the multi-locus analysis of genome-wide association studies
    • Bush WS, Dudek SM, Ritchie MD, (2009) Biofilter: a knowledge-integration system for the multi-locus analysis of genome-wide association studies. Pac Symp Biocomput pp. 368-379.
    • (2009) Pac Symp Biocomput , pp. 368-379
    • Bush, W.S.1    Dudek, S.M.2    Ritchie, M.D.3
  • 42
    • 75849134020 scopus 로고    scopus 로고
    • INTERSNP: genome-wide interaction analysis guided by a priori information
    • doi:10.1093/bioinformatics/btp596
    • Herold C, Steffens M, Brockschmidt FF, Baur MP, Becker T, (2009) INTERSNP: genome-wide interaction analysis guided by a priori information. Bioinformatics 25: 3275-3281 doi: 10.1093/bioinformatics/btp596.
    • (2009) Bioinformatics , vol.25 , pp. 3275-3281
    • Herold, C.1    Steffens, M.2    Brockschmidt, F.F.3    Baur, M.P.4    Becker, T.5
  • 43
    • 34249997024 scopus 로고    scopus 로고
    • Replicating genotype-phenotype associations
    • doi:10.1038/447655a
    • Chanock SJ, Manolio T, Boehnke M, Boerwinkle E, Hunter DJ, et al. (2007) Replicating genotype-phenotype associations. Nature 447: 655-660 doi: 10.1038/447655a.
    • (2007) Nature , vol.447 , pp. 655-660
    • Chanock, S.J.1    Manolio, T.2    Boehnke, M.3    Boerwinkle, E.4    Hunter, D.J.5
  • 44
    • 34147119077 scopus 로고    scopus 로고
    • Overcoming the winner's curse: estimating penetrance parameters from case-control data
    • doi:10.1086/512821
    • Zollner S, Pritchard JK, (2007) Overcoming the winner's curse: estimating penetrance parameters from case-control data. Am J Hum Genet 80: 605-615 doi: 10.1086/512821.
    • (2007) Am J Hum Genet , vol.80 , pp. 605-615
    • Zollner, S.1    Pritchard, J.K.2
  • 45
    • 38649121127 scopus 로고    scopus 로고
    • Common variants in the GDF5-UQCC region are associated with variation in human height
    • doi:10.1038/ng.74
    • Sanna S, Jackson AU, Nagaraja R, Willer CJ, Chen WM, et al. (2008) Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet 40: 198-203 doi: 10.1038/ng.74.
    • (2008) Nat Genet , vol.40 , pp. 198-203
    • Sanna, S.1    Jackson, A.U.2    Nagaraja, R.3    Willer, C.J.4    Chen, W.M.5
  • 46
    • 38649125868 scopus 로고    scopus 로고
    • Newly identified loci that influence lipid concentrations and risk of coronary artery disease
    • doi:10.1038/ng.76
    • Willer CJ, Sanna S, Jackson AU, Scuteri A, Bonnycastle LL, et al. (2008) Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet 40: 161-169 doi: 10.1038/ng.76.
    • (2008) Nat Genet , vol.40 , pp. 161-169
    • Willer, C.J.1    Sanna, S.2    Jackson, A.U.3    Scuteri, A.4    Bonnycastle, L.L.5
  • 47
    • 65249183403 scopus 로고    scopus 로고
    • Meta-analysis in genome-wide association studies
    • doi:10.2217/14622416.10.2.191
    • Zeggini E, Ioannidis JP, (2009) Meta-analysis in genome-wide association studies. Pharmacogenomics 10: 191-201 doi: 10.2217/14622416.10.2.191.
    • (2009) Pharmacogenomics , vol.10 , pp. 191-201
    • Zeggini, E.1    Ioannidis, J.P.2
  • 48
    • 33745700802 scopus 로고    scopus 로고
    • Assessing heterogeneity in meta-analysis: Q statistic or I2 index?
    • doi:10.1037/1082-989X.11.2.193
    • Huedo-Medina TB, Sanchez-Meca J, Marin-Martinez F, Botella J, (2006) Assessing heterogeneity in meta-analysis: Q statistic or I2 index? Psychol Methods 11: 193-206 doi: 10.1037/1082-989X.11.2.193.
    • (2006) Psychol Methods , vol.11 , pp. 193-206
    • Huedo-Medina, T.B.1    Sanchez-Meca, J.2    Marin-Martinez, F.3    Botella, J.4
  • 49
    • 53349129304 scopus 로고    scopus 로고
    • Commentary: Heterogeneity in meta-analysis should be expected and appropriately quantified
    • doi:10.1093/ije/dyn204
    • Higgins JP, (2008) Commentary: Heterogeneity in meta-analysis should be expected and appropriately quantified. Int J Epidemiol 37: 1158-1160 doi: 10.1093/ije/dyn204.
    • (2008) Int J Epidemiol , vol.37 , pp. 1158-1160
    • Higgins, J.P.1
  • 50
  • 51
    • 34347344976 scopus 로고    scopus 로고
    • A new multipoint method for genome-wide association studies by imputation of genotypes
    • doi:10.1038/ng2088
    • Marchini J, Howie B, Myers S, McVean G, Donnelly P, (2007) A new multipoint method for genome-wide association studies by imputation of genotypes. Nat Genet 39: 906-913 doi: 10.1038/ng2088.
    • (2007) Nat Genet , vol.39 , pp. 906-913
    • Marchini, J.1    Howie, B.2    Myers, S.3    McVean, G.4    Donnelly, P.5
  • 52
    • 58149175796 scopus 로고    scopus 로고
    • Practical issues in imputation-based association mapping
    • doi:10.1371/journal.pgen.1000279
    • Guan Y, Stephens M, (2008) Practical issues in imputation-based association mapping. PLoS Genet 4: e1000279 doi: 10.1371/journal.pgen.1000279.
    • (2008) PLoS Genet , vol.4
    • Guan, Y.1    Stephens, M.2
  • 53
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • doi:10.1371/journal.pgen.1000529
    • Howie BN, Donnelly P, Marchini J, (2009) A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet 5: e1000529 doi: 10.1371/journal.pgen.1000529.
    • (2009) PLoS Genet , vol.5
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 55
    • 62649155943 scopus 로고    scopus 로고
    • A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals
    • doi:10.1016/j.ajhg.2009.01.005
    • Browning BL, Browning SR, (2009) A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals. Am J Hum Genet 84: 210-223 doi: 10.1016/j.ajhg.2009.01.005.
    • (2009) Am J Hum Genet , vol.84 , pp. 210-223
    • Browning, B.L.1    Browning, S.R.2


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