Detecting natural selection in genomic data

Annual Review of Genetics

Volumn 47, Issue , 2013, Pages 97-120

  Vitti, Joseph J ^a,b   Grossman, Sharon R ^b,c,d   Sabeti, Pardis C ^a,b  

^a HARVARD UNIVERSITY   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Adaptation; Evolutionary genomics; Genome scans; Population genetics; Selective sweeps

Indexed keywords

HEMOGLOBIN BETA CHAIN; RETINOL; UNTRANSLATED RNA;

ADAPTATION; COPY NUMBER VARIATION; ENDEMIC DISEASE; ERYTHROCYTE; EVOLUTION; FREQUENCY DEPENDENT SELECTION; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENETIC DRIFT; GENETIC POLYMORPHISM; GENOMICS; GENOTYPE; HAPLOTYPE; HETEROZYGOTE; HETEROZYGOTE ADVANTAGE; HOST PATHOGEN INTERACTION; HUMAN; HYPERVITAMINOSIS; INFECTION RESISTANCE; MALARIA; MIGRATION; NATURAL SELECTION; NONHUMAN; PLEIOTROPY; POPULATION GENETICS; PRIORITY JOURNAL; REVIEW; SCORING SYSTEM; SICKLE CELL ANEMIA; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; THALASSEMIA; TRYPANOSOMIASIS; VITAMIN METABOLISM;

ADAPTATION, PHYSIOLOGICAL; ALLELES; AMINO ACID SUBSTITUTION; ANIMALS; EVOLUTION, MOLECULAR; FORECASTING; GENE FREQUENCY; GENETICS, POPULATION; GENOMICS; GENOTYPING TECHNIQUES; HUMANS; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; MULTIFACTORIAL INHERITANCE; MUTATION; MUTATION RATE; PHENOTYPE; SELECTION, GENETIC; SEQUENCE ANALYSIS, DNA;

EID: 84888582669     PISSN: 00664197     EISSN: 15452948     Source Type: Book Series    
DOI: 10.1146/annurev-genet-111212-133526     Document Type: Review

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