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Volumn 44, Issue , 2013, Pages 123-143

Population genomics of human adaptation

Author keywords

Evolution; Human genetics; Population genetics; Whole genome sequencing

Indexed keywords

ADAPTATION; GENETIC VARIATION; GENOMICS; GENOTYPE; HUMAN EVOLUTION; HYPOXIA; IMMUNE SYSTEM; LOCAL ADAPTATION; NATURAL SELECTION; PHENOTYPE; POPULATION STRUCTURE; REPRODUCTION;

EID: 84888598036     PISSN: 1543592X     EISSN: 15452069     Source Type: Book Series    
DOI: 10.1146/annurev-ecolsys-110512-135833     Document Type: Review
Times cited : (68)

References (150)
  • 1
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • 1000 Genomes Proj. Consort.
    • 1000 Genomes Proj. Consort. 2010. A map of human genome variation from population-scale sequencing. Nature 467:1061-73
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 3
    • 65149103048 scopus 로고    scopus 로고
    • Constructing genomic maps of positive selection in humans: Where do we go from here?
    • Akey JM. 2009. Constructing genomic maps of positive selection in humans: where do we go from here? Genome Res. 19:711-22
    • (2009) Genome Res. , vol.19 , pp. 711-722
    • Akey, J.M.1
  • 6
    • 27144491328 scopus 로고    scopus 로고
    • Adaptive evolution of non-coding DNA in Drosophila
    • Andolfatto P. 2005. Adaptive evolution of non-coding DNA in Drosophila. Nature 437:1149-52
    • (2005) Nature , vol.437 , pp. 1149-1152
    • Andolfatto, P.1
  • 7
    • 84859636918 scopus 로고    scopus 로고
    • A fine-scale chimpanzee genetic map from population sequencing
    • Auton A, Fledel-Alon A, Pfeifer S, Venn O, Segurel L, et al. 2012. A fine-scale chimpanzee genetic map from population sequencing. Science 336:193-98
    • (2012) Science , vol.336 , pp. 193-198
    • Auton, A.1    Fledel-Alon, A.2    Pfeifer, S.3    Venn, O.4    Segurel, L.5
  • 8
    • 84877585022 scopus 로고    scopus 로고
    • FOXP2 targets show evidence of positive selection in European populations
    • Ayub Q, Yngvadottir B, Chen Y, Xue Y, Hu M, et al. 2013. FOXP2 targets show evidence of positive selection in European populations. Am. J. Hum. Genet. 92:696-706
    • (2013) Am. J. Hum. Genet. , vol.92 , pp. 696-706
    • Ayub, Q.1    Yngvadottir, B.2    Chen, Y.3    Xue, Y.4    Hu, M.5
  • 9
    • 34250659350 scopus 로고    scopus 로고
    • More genes underwent positive selection in chimpanzee evolution than in human evolution
    • Bakewell MA, Shi P, Zhang J. 2007. More genes underwent positive selection in chimpanzee evolution than in human evolution. Proc. Natl. Acad. Sci. USA 104:7489-94
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 7489-7494
    • Bakewell, M.A.1    Shi, P.2    Zhang, J.3
  • 10
    • 34547539515 scopus 로고    scopus 로고
    • Andean, Tibetan, and Ethiopian patterns of adaptation to high-altitude hypoxia
    • Beall CM. 2006. Andean, Tibetan, and Ethiopian patterns of adaptation to high-altitude hypoxia. Integr. Comp. Biol. 46:18-24
    • (2006) Integr. Comp. Biol. , vol.46 , pp. 18-24
    • Beall, C.M.1
  • 11
    • 1642269679 scopus 로고    scopus 로고
    • Identifying adaptive genetic divergence among populations from genome scans
    • Beaumont MA, Balding DJ. 2004. Identifying adaptive genetic divergence among populations from genome scans. Mol. Ecol. 13:969-80
    • (2004) Mol. Ecol. , vol.13 , pp. 969-980
    • Beaumont, M.A.1    Balding, D.J.2
  • 12
    • 0036964474 scopus 로고    scopus 로고
    • Approximate Bayesian computation in population genetics
    • Beaumont MA, Zhang W, Balding DJ. 2002. Approximate Bayesian computation in population genetics. Genetics 162:2025-35
    • (2002) Genetics , vol.162 , pp. 2025-2035
    • Beaumont, M.A.1    Zhang, W.2    Balding, D.J.3
  • 15
    • 76249086956 scopus 로고    scopus 로고
    • Identifying positive selection candidate loci for high-altitude adaptation in Andean populations
    • Bigham AW, Mao X, Mei R, Brutsaert T, Wilson MJ, et al. 2009. Identifying positive selection candidate loci for high-altitude adaptation in Andean populations. Hum. Genomics 4:79-90
    • (2009) Hum. Genomics , vol.4 , pp. 79-90
    • Bigham, A.W.1    Mao, X.2    Mei, R.3    Brutsaert, T.4    Wilson, M.J.5
  • 18
    • 34548133728 scopus 로고    scopus 로고
    • Predicting functionally important residues from sequence conservation
    • Capra JA, Singh M. 2007. Predicting functionally important residues from sequence conservation. Bioinformatics 23:1875-82
    • (2007) Bioinformatics , vol.23 , pp. 1875-1882
    • Capra, J.A.1    Singh, M.2
  • 19
    • 0037370384 scopus 로고    scopus 로고
    • The application of molecular genetic approaches to the study of human evolution
    • Cavalli-Sforza LL, Feldman MW. 2003. The application of molecular genetic approaches to the study of human evolution. Nat. Genet. 33(Suppl.):266-75
    • (2003) Nat. Genet. , vol.33 , Issue.SUPPL. , pp. 266-275
    • Cavalli-Sforza, L.L.1    Feldman, M.W.2
  • 20
    • 0035130163 scopus 로고    scopus 로고
    • Genomic divergences between humans and other hominoids and the effective population size of the common ancestor of humans and chimpanzees
    • Chen FC, Li WH. 2001. Genomic divergences between humans and other hominoids and the effective population size of the common ancestor of humans and chimpanzees. Am. J. Hum. Genet. 68:444-56
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 444-456
    • Chen, F.C.1    Li, W.H.2
  • 21
    • 77649260327 scopus 로고    scopus 로고
    • Population differentiation as a test for selective sweeps
    • Chen H, Patterson N, Reich D. 2010. Population differentiation as a test for selective sweeps. Genome Res. 20:393-402
    • (2010) Genome Res. , vol.20 , pp. 393-402
    • Chen, H.1    Patterson, N.2    Reich, D.3
  • 24
    • 77956491134 scopus 로고    scopus 로고
    • Using environmental correlations to identify loci underlying loci adaptation
    • Coop G, Witonsky DB, Di Rienzo A, Pritchard JK. 2010. Using environmental correlations to identify loci underlying loci adaptation. Genetics 185:1411-23
    • (2010) Genetics , vol.185 , pp. 1411-1423
    • Coop, G.1    Witonsky, D.B.2    Di Rienzo, A.3    Pritchard, J.K.4
  • 27
    • 70349507629 scopus 로고    scopus 로고
    • Out of Africa: Modern human origins special feature: Explaining worldwide patterns of human genetic variation using a coalescent-based serial founder model of migration outward from Africa
    • DeGiorgio M, Jakobsson M, Rosenberg NA. 2009. Out of Africa: modern human origins special feature: explaining worldwide patterns of human genetic variation using a coalescent-based serial founder model of migration outward from Africa. Proc. Natl. Acad. Sci. USA 106:16057-62
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 16057-16062
    • Degiorgio, M.1    Jakobsson, M.2    Rosenberg, N.A.3
  • 29
    • 0030024686 scopus 로고    scopus 로고
    • Infectious diseases and human population history
    • Dobson AP, Carper ER. 1996. Infectious diseases and human population history. BioScience 46:115-26
    • (1996) BioScience , vol.46 , pp. 115-126
    • Dobson, A.P.1    Carper, E.R.2
  • 30
    • 74949138753 scopus 로고    scopus 로고
    • Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays
    • Drmanac R, Sparks AB, Callow MJ, Halpern AL, Burns NL, et al. 2010. Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays. Science 327:78-81
    • (2010) Science , vol.327 , pp. 78-81
    • Drmanac, R.1    Sparks, A.B.2    Callow, M.J.3    Halpern, A.L.4    Burns, N.L.5
  • 31
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • Dunham I, Kundaje A, Aldred SF, Collins PJ, Davis CA, et al. 2012. An integrated encyclopedia of DNA elements in the human genome. Nature 489:57-74
    • (2012) Nature , vol.489 , pp. 57-74
    • Dunham, I.1    Kundaje, A.2    Aldred, S.F.3    Collins, P.J.4    Davis, C.A.5
  • 32
    • 0006547393 scopus 로고
    • Cultural mediation: The evolution of adult lactose absorption
    • Stanford, CA: Stanford Univ. Press
    • Durham WH. 1992. Cultural mediation: The evolution of adult lactose absorption. In Coevolution: Genes, Culture, and Human Diversity, pp. 226-85. Stanford, CA: Stanford Univ. Press
    • (1992) Coevolution: Genes, Culture, and Human Diversity , pp. 226-285
    • Durham, W.H.1
  • 34
    • 0037158715 scopus 로고    scopus 로고
    • Molecular evolution of FOXP2, a gene involved in speech and language
    • Enard W, Przeworski M, Fisher SE, Lai CS, Wiebe V, et al. 2002. Molecular evolution of FOXP2, a gene involved in speech and language. Nature 418:869-72
    • (2002) Nature , vol.418 , pp. 869-872
    • Enard, W.1    Przeworski, M.2    Fisher, S.E.3    Lai, C.S.4    Wiebe, V.5
  • 35
    • 38749131273 scopus 로고    scopus 로고
    • Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture
    • Enattah NS, Jensen TG, Nielsen M, Lewinski R, Kuokkanen M, et al. 2008. Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture. Am. J. Hum. Genet. 82:57-72
    • (2008) Am. J. Hum. Genet. , vol.82 , pp. 57-72
    • Enattah, N.S.1    Jensen, T.G.2    Nielsen, M.3    Lewinski, R.4    Kuokkanen, M.5
  • 36
    • 68949202924 scopus 로고    scopus 로고
    • Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change
    • Eyre-Walker A, Keightley PD. 2009. Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change. Mol. Biol. Evol. 26:2097-108
    • (2009) Mol. Biol. Evol. , vol.26 , pp. 2097-2108
    • Eyre-Walker, A.1    Keightley, P.D.2
  • 37
    • 0033911640 scopus 로고    scopus 로고
    • Hitchhiking under positive Darwinian selection
    • Fay JC, Wu CI. 2000. Hitchhiking under positive Darwinian selection. Genetics 155:1405-13
    • (2000) Genetics , vol.155 , pp. 1405-1413
    • Fay, J.C.1    Wu, C.I.2
  • 38
    • 50649098835 scopus 로고    scopus 로고
    • A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia
    • Fujimoto A, Ohashi J, Nishida N, Miyagawa T, Morishita Y, et al. 2008. A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia. Hum. Genet. 124:179-85
    • (2008) Hum. Genet. , vol.124 , pp. 179-185
    • Fujimoto, A.1    Ohashi, J.2    Nishida, N.3    Miyagawa, T.4    Morishita, Y.5
  • 39
    • 81755177812 scopus 로고    scopus 로고
    • Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution
    • Fumagalli M, Sironi M, Pozzoli U, Ferrer-Admetlla A, Pattini L, Nielsen R. 2011. Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution. PLoS Genet. 7:e1002355
    • (2011) PLoS Genet. , vol.7
    • Fumagalli, M.1    Sironi, M.2    Pozzoli, U.3    Ferrer-Admetlla, A.4    Pattini, L.5    Nielsen, R.6
  • 40
    • 34248641119 scopus 로고    scopus 로고
    • Adaptation or biased gene conversion? Extending the null hypothesis of molecular evolution
    • Galtier N, Duret L. 2007. Adaptation or biased gene conversion? Extending the null hypothesis of molecular evolution. Trends Genet. 23:273-77
    • (2007) Trends Genet. , vol.23 , pp. 273-277
    • Galtier, N.1    Duret, L.2
  • 41
    • 77955646179 scopus 로고    scopus 로고
    • Association of trypanolytic ApoL1 variants with kidney disease in African Americans
    • Genovese G, Friedman DJ, Ross MD, Lecordier L, Uzureau P, et al. 2010. Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science 329:841-45
    • (2010) Science , vol.329 , pp. 841-845
    • Genovese, G.1    Friedman, D.J.2    Ross, M.D.3    Lecordier, L.4    Uzureau, P.5
  • 42
    • 0037357461 scopus 로고    scopus 로고
    • Estimation of divergence times for major lineages of primate species
    • Glazko GV, Nei M. 2003. Estimation of divergence times for major lineages of primate species. Mol. Biol. Evol. 20:424-34
    • (2003) Mol. Biol. Evol. , vol.20 , pp. 424-434
    • Glazko, G.V.1    Nei, M.2
  • 43
    • 0028168856 scopus 로고
    • A codon-based model of nucleotide substitution for protein-coding DNA sequences
    • Goldman N, Yang Z. 1994. A codon-based model of nucleotide substitution for protein-coding DNA sequences. Mol. Biol. Evol. 11:725-36
    • (1994) Mol. Biol. Evol. , vol.11 , pp. 725-736
    • Goldman, N.1    Yang, Z.2
  • 44
    • 0035943090 scopus 로고    scopus 로고
    • Population genomics: Linkage disequilibrium holds the key
    • Goldstein DB, Weale ME. 2001. Population genomics: linkage disequilibrium holds the key. Curr. Biol. 11:R576-79
    • (2001) Curr. Biol. , vol.11
    • Goldstein, D.B.1    Weale, M.E.2
  • 45
  • 46
    • 0018692402 scopus 로고
    • The spandrels of San Marco and the Panglossian paradigm: A critique of the adaptationist programme
    • Gould SJ, Lewontin RC. 1979. The spandrels of San Marco and the Panglossian paradigm: a critique of the adaptationist programme. Proc. R. Soc. Lond. B 205:581-98
    • (1979) Proc. R. Soc. Lond. B , vol.205 , pp. 581-598
    • Gould, S.J.1    Lewontin, R.C.2
  • 48
    • 84879402049 scopus 로고    scopus 로고
    • Elevated evolutionary rates among functionally diverged reproductive genes across deep vertebrate lineages
    • Grassa CJ, Kulathinal RJ. 2011. Elevated evolutionary rates among functionally diverged reproductive genes across deep vertebrate lineages. Int. J. Evol. Biol. 2011:274975
    • (2011) Int. J. Evol. Biol. , vol.2011 , pp. 274975
    • Grassa, C.J.1    Kulathinal, R.J.2
  • 51
    • 76749155514 scopus 로고    scopus 로고
    • A composite of multiple signals distinguishes causal variants in regions of positive selection
    • Grossman SR, Shlyakhter I, Karlsson EK, Byrne EH, Morales S, et al. 2010. A composite of multiple signals distinguishes causal variants in regions of positive selection. Science 327:883-86
    • (2010) Science , vol.327 , pp. 883-886
    • Grossman, S.R.1    Shlyakhter, I.2    Karlsson, E.K.3    Byrne, E.H.4    Morales, S.5
  • 54
    • 77952405169 scopus 로고    scopus 로고
    • Colloquium paper: Human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency
    • Hancock AM, Witonsky DB, Ehler E, Alkorta-Aranburu G, Beall C, et al. 2010. Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency. Proc. Natl. Acad. Sci. USA 107(Suppl. 2):8924-30
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , Issue.SUPPL. 2 , pp. 8924-8930
    • Hancock, A.M.1    Witonsky, D.B.2    Ehler, E.3    Alkorta-Aranburu, G.4    Beall, C.5
  • 56
  • 57
    • 67249117049 scopus 로고    scopus 로고
    • Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
    • Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, et al. 2009. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc. Natl. Acad. Sci. USA 106:9362-67
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 9362-9367
    • Hindorff, L.A.1    Sethupathy, P.2    Junkins, H.A.3    Ramos, E.M.4    Mehta, J.P.5
  • 58
    • 58149293053 scopus 로고    scopus 로고
    • Large allele frequency differences between human continental groups are more likely to have occurred by drift during range expansions than by selection
    • Hofer T, Ray N, Wegmann D, Excoffier L. 2009. Large allele frequency differences between human continental groups are more likely to have occurred by drift during range expansions than by selection. Ann. Hum. Genet. 73:95-108
    • (2009) Ann. Hum. Genet. , vol.73 , pp. 95-108
    • Hofer, T.1    Ray, N.2    Wegmann, D.3    Excoffier, L.4
  • 59
    • 79959924827 scopus 로고    scopus 로고
    • Evolution of the brain in humans-paleoneurology
    • ed. MD Binder, N Hirokawa, U Windhorst New York: Springer
    • Holloway RL, Sherwood CS, Hof PR, Rilling JK. 2009. Evolution of the brain in humans-paleoneurology. In Encyclopedia of Neuroscience, ed. MD Binder, N Hirokawa, U Windhorst, pp. 1326-34. New York: Springer
    • (2009) Encyclopedia of Neuroscience , pp. 1326-1334
    • Holloway, R.L.1    Sherwood, C.S.2    Hof, P.R.3    Rilling, J.K.4
  • 60
    • 4844229391 scopus 로고    scopus 로고
    • Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes
    • Huang H, Winter EE, Wang H, Weinstock KG, Xing H, et al. 2004. Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes. Genome Biol. 5:R47
    • (2004) Genome Biol. , vol.5
    • Huang, H.1    Winter, E.E.2    Wang, H.3    Weinstock, K.G.4    Xing, H.5
  • 61
    • 0036184745 scopus 로고    scopus 로고
    • Generating samples under a Wright-Fisher neutral model of genetic variation
    • Hudson RR. 2002. Generating samples under a Wright-Fisher neutral model of genetic variation. Bioinformatics 18:337-38
    • (2002) Bioinformatics , vol.18 , pp. 337-338
    • Hudson, R.R.1
  • 62
    • 33846343947 scopus 로고    scopus 로고
    • A novel polymorphism associated with lactose tolerance in Africa: Multiple causes for lactase persistence?
    • Ingram CJ, Elamin MF, Mulcare CA, Weale ME, Tarekegn A, et al. 2007. A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence? Hum. Genet. 120:779-88
    • (2007) Hum. Genet. , vol.120 , pp. 779-788
    • Ingram, C.J.1    Elamin, M.F.2    Mulcare, C.A.3    Weale, M.E.4    Tarekegn, A.5
  • 63
    • 84868222723 scopus 로고    scopus 로고
    • Human skin pigmentation as an example of adaptive evolution
    • Jablonski NG. 2012. Human skin pigmentation as an example of adaptive evolution. Proc. Am. Philos. Soc. 156:45-57
    • (2012) Proc. Am. Philos. Soc. , vol.156 , pp. 45-57
    • Jablonski, N.G.1
  • 64
    • 23344438911 scopus 로고    scopus 로고
    • Distinguishing between selective sweeps and demography using DNA polymorphism data
    • Jensen JD, Kim Y, DuMont VB, Aquadro CF, Bustamante CD. 2005. Distinguishing between selective sweeps and demography using DNA polymorphism data. Genetics 170:1401-10
    • (2005) Genetics , vol.170 , pp. 1401-1410
    • Jensen, J.D.1    Kim, Y.2    Dumont, V.B.3    Aquadro, C.F.4    Bustamante, C.D.5
  • 65
    • 84883162851 scopus 로고    scopus 로고
    • Comparison of the performance of two commercial genome-wide association study genotyping platforms in Han Chinese samples
    • Jiang L, Willner D, Danoy P, Xu H, Brown MA. 2013. Comparison of the performance of two commercial genome-wide association study genotyping platforms in Han Chinese samples. G3 (Bethesda) 3:23-29
    • (2013) G3 (Bethesda) , vol.3 , pp. 23-29
    • Jiang, L.1    Willner, D.2    Danoy, P.3    Xu, H.4    Brown, M.A.5
  • 68
    • 0035474085 scopus 로고    scopus 로고
    • Population genomics: A bridge from evolutionary history to genetic medicine
    • Jorde LB, Watkins WS, Bamshad MJ. 2001. Population genomics: a bridge from evolutionary history to genetic medicine. Hum. Mol. Genet. 10:2199-207
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2199-2207
    • Jorde, L.B.1    Watkins, W.S.2    Bamshad, M.J.3
  • 69
    • 84874048561 scopus 로고    scopus 로고
    • Modeling recent human evolution in mice by expression of a selected EDAR variant
    • Kamberov YG, Wang S, Tan J, Gerbault P, Wark A, et al. 2013. Modeling recent human evolution in mice by expression of a selected EDAR variant. Cell 152:691-702
    • (2013) Cell , vol.152 , pp. 691-702
    • Kamberov, Y.G.1    Wang, S.2    Tan, J.3    Gerbault, P.4    Wark, A.5
  • 70
    • 59349100553 scopus 로고    scopus 로고
    • Out of Africa and the evolution of human behavior
    • Klein RG. 2008. Out of Africa and the evolution of human behavior. Evol. Anthropol. 17:267-81
    • (2008) Evol. Anthropol. , vol.17 , pp. 267-281
    • Klein, R.G.1
  • 72
    • 78049354879 scopus 로고    scopus 로고
    • Fine-scale recombination rate differences between sexes, populations and individuals
    • Kong A, Thorleifsson G, Gudbjartsson DF, Masson G, Sigurdsson A, et al. 2010. Fine-scale recombination rate differences between sexes, populations and individuals. Nature 467:1099-103
    • (2010) Nature , vol.467 , pp. 1099-1103
    • Kong, A.1    Thorleifsson, G.2    Gudbjartsson, D.F.3    Masson, G.4    Sigurdsson, A.5
  • 73
    • 35548955882 scopus 로고    scopus 로고
    • The derived FOXP2 variant of modern humans was shared with Neandertals
    • Krause J, Lalueza-Fox C, Orlando L, Enard W, Green RE, et al. 2007. The derived FOXP2 variant of modern humans was shared with Neandertals. Curr. Biol. 17:1908-12
    • (2007) Curr. Biol. , vol.17 , pp. 1908-1912
    • Krause, J.1    Lalueza-Fox, C.2    Orlando, L.3    Enard, W.4    Green, R.E.5
  • 75
    • 68149165614 scopus 로고    scopus 로고
    • Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm
    • Kumar P, Henikoff S, Ng PC. 2009. Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat. Protoc. 4:1073-81
    • (2009) Nat. Protoc. , vol.4 , pp. 1073-1081
    • Kumar, P.1    Henikoff, S.2    Ng, P.C.3
  • 76
    • 78651353592 scopus 로고    scopus 로고
    • Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations
    • Lachance J. 2010. Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations. BMC Med. Genomics 3:57
    • (2010) BMC Med. Genomics , vol.3 , pp. 57
    • Lachance, J.1
  • 77
    • 84881616630 scopus 로고    scopus 로고
    • SNP ascertainment bias in population genetic analyses: Why it is important and how to correct it
    • Lachance J, Tishkoff SA. 2013. SNP ascertainment bias in population genetic analyses: Why it is important and how to correct it. BioEssays. 35:780-86
    • (2013) BioEssays. , vol.35 , pp. 780-786
    • Lachance, J.1    Tishkoff, S.A.2
  • 78
    • 84864576715 scopus 로고    scopus 로고
    • Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers
    • Lachance J, Vernot B, Elbers CC, Ferwerda B, Froment A, et al. 2012. Evolutionary history and adaptation from high-coverage whole-genome sequences of diverse African hunter-gatherers. Cell 150:457-69
    • (2012) Cell , vol.150 , pp. 457-469
    • Lachance, J.1    Vernot, B.2    Elbers, C.C.3    Ferwerda, B.4    Froment, A.5
  • 81
    • 7244221627 scopus 로고    scopus 로고
    • SIMCOAL 2.0: A program to simulate genomic diversity over large recombining regions in a subdivided population with a complex history
    • Laval G, Excoffier L. 2004. SIMCOAL 2.0: a program to simulate genomic diversity over large recombining regions in a subdivided population with a complex history. Bioinformatics 20:2485-87
    • (2004) Bioinformatics , vol.20 , pp. 2485-2487
    • Laval, G.1    Excoffier, L.2
  • 83
    • 0015879546 scopus 로고
    • Distribution of gene frequency as a test of the theory of the selective neutrality of polymorphisms
    • Lewontin RC, Krakauer J. 1973. Distribution of gene frequency as a test of the theory of the selective neutrality of polymorphisms. Genetics 74:175-95
    • (1973) Genetics , vol.74 , pp. 175-195
    • Lewontin, R.C.1    Krakauer, J.2
  • 84
    • 78650470089 scopus 로고    scopus 로고
    • A new test for detecting recent positive selection that is free from the confounding impacts of demography
    • Li H. 2011. A new test for detecting recent positive selection that is free from the confounding impacts of demography. Mol. Biol. Evol. 28:365-75
    • (2011) Mol. Biol. Evol. , vol.28 , pp. 365-375
    • Li, H.1
  • 86
    • 39749139577 scopus 로고    scopus 로고
    • Proportionally more deleterious genetic variation in European than in African populations
    • Lohmueller KE, Indap AR, Schmidt S, Boyko AR, Hernandez RD, et al. 2008. Proportionally more deleterious genetic variation in European than in African populations. Nature 451:994-97
    • (2008) Nature , vol.451 , pp. 994-997
    • Lohmueller, K.E.1    Indap, A.R.2    Schmidt, S.3    Boyko, A.R.4    Hernandez, R.D.5
  • 87
  • 88
    • 24044455869 scopus 로고    scopus 로고
    • Genome sequencing in microfabricated high-density picolitre reactors
    • Margulies M, Egholm M, Altman WE, Attiya S, Bader JS, et al. 2005. Genome sequencing in microfabricated high-density picolitre reactors. Nature 437:376-80
    • (2005) Nature , vol.437 , pp. 376-380
    • Margulies, M.1    Egholm, M.2    Altman, W.E.3    Attiya, S.4    Bader, J.S.5
  • 89
    • 0026428610 scopus 로고
    • Adaptive protein evolution at the Adh locus in Drosophila
    • McDonald JH, Kreitman M. 1991. Adaptive protein evolution at the Adh locus in Drosophila. Nature 351:652-54
    • (1991) Nature , vol.351 , pp. 652-654
    • McDonald, J.H.1    Kreitman, M.2
  • 90
    • 13944279562 scopus 로고    scopus 로고
    • Stratigraphic placement and age of modern humans from Kibish, Ethiopia
    • McDougall I, Brown FH, Fleagle JG. 2005. Stratigraphic placement and age of modern humans from Kibish, Ethiopia. Nature 433:733-76
    • (2005) Nature , vol.433 , pp. 733-776
    • McDougall, I.1    Brown, F.H.2    Fleagle, J.G.3
  • 91
    • 33749033325 scopus 로고    scopus 로고
    • The genetic architecture of normal variation in human pigmentation: An evolutionary perspective and model
    • Spec. No. 2
    • McEvoy B, Beleza S, Shriver MD. 2006. The genetic architecture of normal variation in human pigmentation: an evolutionary perspective and model. Hum. Mol. Genet. 15(Spec. No. 2):R176-81
    • (2006) Hum. Mol. Genet. , vol.15
    • McEvoy, B.1    Beleza, S.2    Shriver, M.D.3
  • 92
    • 79957956814 scopus 로고    scopus 로고
    • Human population dispersal "out of Africa" estimated from linkage disequilibrium and allele frequencies of SNPs
    • McEvoy BP, Powell JE, Goddard ME, Visscher PM. 2011. Human population dispersal "Out of Africa" estimated from linkage disequilibrium and allele frequencies of SNPs. Genome Res. 21:821-29
    • (2011) Genome Res. , vol.21 , pp. 821-829
    • McEvoy, B.P.1    Powell, J.E.2    Goddard, M.E.3    Visscher, P.M.4
  • 93
    • 84888619150 scopus 로고    scopus 로고
    • Origin and diversity of early hominin bipedalism
    • ed. SC Reynolds, A Gallagher Cambridge, UK: Cambridge Univ. Press
    • McHenry HM. 2012. Origin and diversity of early hominin bipedalism. In African Genesis: Perspectives on Hominin Evolution, ed. SC Reynolds, A Gallagher, pp. 205-22. Cambridge, UK: Cambridge Univ. Press
    • (2012) African Genesis: Perspectives on Hominin Evolution , pp. 205-222
    • McHenry, H.M.1
  • 94
    • 1942454876 scopus 로고    scopus 로고
    • Maternal adaptation to high-altitude pregnancy: An experiment of nature - A review
    • Moore LG, Shriver M, Bemis L, Hickler B, Wilson M, et al. 2004. Maternal adaptation to high-altitude pregnancy: an experiment of nature-a review. Placenta 25(Suppl. A):S60-71
    • (2004) Placenta , vol.25 , Issue.SUPPL. A
    • Moore, L.G.1    Shriver, M.2    Bemis, L.3    Hickler, B.4    Wilson, M.5
  • 95
    • 82255175508 scopus 로고    scopus 로고
    • Deep human genealogies reveal a selective advantage to be on an expanding wave front
    • Moreau C, Bherer C, Vezina H, Jomphe M, Labuda D, Excoffier L. 2011. Deep human genealogies reveal a selective advantage to be on an expanding wave front. Science 334:1148-50
    • (2011) Science , vol.334 , pp. 1148-1150
    • Moreau, C.1    Bherer, C.2    Vezina, H.3    Jomphe, M.4    Labuda, D.5    Excoffier, L.6
  • 96
    • 79951750950 scopus 로고    scopus 로고
    • Comparison of F(ST) outlier tests for SNP loci under selection
    • Narum SR, Hess JE. 2011. Comparison of F(ST) outlier tests for SNP loci under selection. Mol. Ecol. Resour. 11(Suppl. 1):184-94
    • (2011) Mol. Ecol. Resour. , vol.11 , Issue.SUPPL. 1 , pp. 184-194
    • Narum, S.R.1    Hess, J.E.2
  • 97
    • 70349566593 scopus 로고
    • Diabetes mellitus: A "thrifty" genotype rendered detrimental by "progress"?
    • Neel JV. 1962. Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? Am. J. Hum. Genet. 14:353-62
    • (1962) Am. J. Hum. Genet. , vol.14 , pp. 353-362
    • Neel, J.V.1
  • 98
    • 0016516814 scopus 로고
    • Letters to the editors: Lewontin-Krakauer test for neutral genes
    • Nei M, Maruyama T. 1975. Letters to the editors: Lewontin-Krakauer test for neutral genes. Genetics 80:395
    • (1975) Genetics , vol.80 , pp. 395
    • Nei, M.1    Maruyama, T.2
  • 99
    • 3442885665 scopus 로고    scopus 로고
    • Population genetic analysis of ascertained SNP data
    • Nielsen R. 2004. Population genetic analysis of ascertained SNP data. Hum. Genomics 1:218-24
    • (2004) Hum. Genomics , vol.1 , pp. 218-224
    • Nielsen, R.1
  • 101
    • 84865677151 scopus 로고    scopus 로고
    • Effects of an Asian-specific non-synonymous EDAR variant on multiple dental traits
    • Park JH, Yamaguchi T, Watanabe C, Kawaguchi A, Haneji K, et al. 2012. Effects of an Asian-specific non-synonymous EDAR variant on multiple dental traits. J. Hum. Genet. 57:508-14
    • (2012) J. Hum. Genet. , vol.57 , pp. 508-514
    • Park, J.H.1    Yamaguchi, T.2    Watanabe, C.3    Kawaguchi, A.4    Haneji, K.5
  • 102
    • 84866933213 scopus 로고    scopus 로고
    • A critical assessment of storytelling: Gene ontology categories and the importance of validating genomic scans
    • Pavlidis P, Jensen JD, Stephan W, Stamatakis A. 2012. A critical assessment of storytelling: gene ontology categories and the importance of validating genomic scans. Mol. Biol. Evol. 29:3237-48
    • (2012) Mol. Biol. Evol. , vol.29 , pp. 3237-3248
    • Pavlidis, P.1    Jensen, J.D.2    Stephan, W.3    Stamatakis, A.4
  • 103
    • 33845971545 scopus 로고    scopus 로고
    • Soft sweeps III: The signature of positive selection from recurrent mutation
    • Pennings PS, Hermisson J. 2006. Soft sweeps III: the signature of positive selection from recurrent mutation. PLoS Genet. 2:e186
    • (2006) PLoS Genet. , vol.2
    • Pennings, P.S.1    Hermisson, J.2
  • 104
    • 66049157487 scopus 로고    scopus 로고
    • Signals of recent positive selection in a worldwide sample of human populations
    • Pickrell JK, Coop G, Novembre J, Kudaravalli S, Li JZ, et al. 2009. Signals of recent positive selection in a worldwide sample of human populations. Genome Res. 19:826-37
    • (2009) Genome Res. , vol.19 , pp. 826-837
    • Pickrell, J.K.1    Coop, G.2    Novembre, J.3    Kudaravalli, S.4    Li, J.Z.5
  • 105
    • 33748675254 scopus 로고    scopus 로고
    • An RNA gene expressed during cortical development evolved rapidly in humans
    • Pollard KS, Salama SR, Lambert N, Lambot MA, Coppens S, et al. 2006. An RNA gene expressed during cortical development evolved rapidly in humans. Nature 443:167-72
    • (2006) Nature , vol.443 , pp. 167-172
    • Pollard, K.S.1    Salama, S.R.2    Lambert, N.3    Lambot, M.A.4    Coppens, S.5
  • 106
    • 33748650246 scopus 로고    scopus 로고
    • Evolutionary biology: Human brain gene wins genome race
    • Ponting CP, Lunter G. 2006. Evolutionary biology: human brain gene wins genome race. Nature 443:149-50
    • (2006) Nature , vol.443 , pp. 149-150
    • Ponting, C.P.1    Lunter, G.2
  • 107
    • 58149159713 scopus 로고    scopus 로고
    • Effects of cis and trans genetic ancestry on gene expression in African Americans
    • Price AL, Patterson N, Hancks DC, Myers S, Reich D, et al. 2008. Effects of cis and trans genetic ancestry on gene expression in African Americans. PLoS Genet. 4:e1000294
    • (2008) PLoS Genet. , vol.4
    • Price, A.L.1    Patterson, N.2    Hancks, D.C.3    Myers, S.4    Reich, D.5
  • 108
    • 76749097550 scopus 로고    scopus 로고
    • The genetics of human adaptation: Hard sweeps, soft sweeps, and polygenic adaptation
    • Pritchard JK, Pickrell JK, Coop G. 2010. The genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptation. Curr. Biol. 20:R208-15
    • (2010) Curr. Biol. , vol.20
    • Pritchard, J.K.1    Pickrell, J.K.2    Coop, G.3
  • 109
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. 2007. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81:559-75
    • (2007) Am. J. Hum. Genet. , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.5
  • 110
    • 80053581951 scopus 로고    scopus 로고
    • An Aboriginal Australian genome reveals separate human dispersals into Asia
    • Rasmussen M, Guo X, Wang Y, Lohmueller KE, Rasmussen S, et al. 2011. An Aboriginal Australian genome reveals separate human dispersals into Asia. Science 334:94-98
    • (2011) Science , vol.334 , pp. 94-98
    • Rasmussen, M.1    Guo, X.2    Wang, Y.3    Lohmueller, K.E.4    Rasmussen, S.5
  • 113
    • 78650850475 scopus 로고    scopus 로고
    • Genetic history of an archaic hominin group from Denisova Cave in Siberia
    • Reich D, Green RE, Kircher M, Krause J, Patterson N, et al. 2010. Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature 468:1053-60
    • (2010) Nature , vol.468 , pp. 1053-1060
    • Reich, D.1    Green, R.E.2    Kircher, M.3    Krause, J.4    Patterson, N.5
  • 114
    • 77952324522 scopus 로고    scopus 로고
    • Colloquium paper: Gene-culture coevolution in the age of genomics
    • Richerson PJ, Boyd R, Henrich J. 2010. Colloquium paper: gene-culture coevolution in the age of genomics. Proc. Natl. Acad. Sci. USA 107(Suppl. 2):8985-92
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , Issue.SUPPL. 2 , pp. 8985-8992
    • Richerson, P.J.1    Boyd, R.2    Henrich, J.3
  • 115
    • 0016513539 scopus 로고
    • Letters to the editors: Remarks on the Lewontin-Krakauer test
    • Robertson A. 1975. Letters to the editors: Remarks on the Lewontin-Krakauer test. Genetics 80:396
    • (1975) Genetics , vol.80 , pp. 396
    • Robertson, A.1
  • 116
    • 33645470450 scopus 로고    scopus 로고
    • Genome-wide scans for loci under selection in humans
    • Ronald J, Akey JM. 2005. Genome-wide scans for loci under selection in humans. Hum. Genomics 2:113-25
    • (2005) Hum. Genomics , vol.2 , pp. 113-125
    • Ronald, J.1    Akey, J.M.2
  • 117
    • 0037167852 scopus 로고    scopus 로고
    • Detecting recent positive selection in the human genome from haplotype structure
    • Sabeti PC, Reich DE, Higgins JM, Levine HZ, Richter DJ, et al. 2002. Detecting recent positive selection in the human genome from haplotype structure. Nature 419:832-37
    • (2002) Nature , vol.419 , pp. 832-837
    • Sabeti, P.C.1    Reich, D.E.2    Higgins, J.M.3    Levine, H.Z.4    Richter, D.J.5
  • 118
    • 35349012592 scopus 로고    scopus 로고
    • Genome-wide detection and characterization of positive selection in human populations
    • Sabeti PC, Varilly P, Fry B, Lohmueller J, Hostetter E, et al. 2007. Genome-wide detection and characterization of positive selection in human populations. Nature 449:913-18
    • (2007) Nature , vol.449 , pp. 913-918
    • Sabeti, P.C.1    Varilly, P.2    Fry, B.3    Lohmueller, J.4    Hostetter, E.5
  • 119
    • 0026460082 scopus 로고
    • Population genetics of polymorphism and divergence
    • Sawyer SA, Hartl DL. 1992. Population genetics of polymorphism and divergence. Genetics 132:1161-76
    • (1992) Genetics , vol.132 , pp. 1161-1176
    • Sawyer, S.A.1    Hartl, D.L.2
  • 120
    • 84865856910 scopus 로고    scopus 로고
    • Revising the human mutation rate: Implications for understanding human evolution
    • Scally A, Durbin R. 2012. Revising the human mutation rate: implications for understanding human evolution. Nat. Rev. Genet. 13:745-53
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 745-753
    • Scally, A.1    Durbin, R.2
  • 122
    • 79952276736 scopus 로고    scopus 로고
    • Living the high life: High-altitude adaptation
    • Scheinfeldt LB, Tishkoff SA. 2010. Living the high life: high-altitude adaptation. Genome Biol. 11:133
    • (2010) Genome Biol. , vol.11 , pp. 133
    • Scheinfeldt, L.B.1    Tishkoff, S.A.2
  • 123
    • 84867669367 scopus 로고    scopus 로고
    • Genomic variation in seven Khoe-San groups reveals adaptation and complex African history
    • Schlebusch CM, Skoglund P, Sjodin P, Gattepaille LM, Hernandez D, et al. 2012. Genomic variation in seven Khoe-San groups reveals adaptation and complex African history. Science 338:374-79
    • (2012) Science , vol.338 , pp. 374-379
    • Schlebusch, C.M.1    Skoglund, P.2    Sjodin, P.3    Gattepaille, L.M.4    Hernandez, D.5
  • 124
    • 52649116609 scopus 로고    scopus 로고
    • A tutorial of the poisson random field model in population genetics
    • Sethupathy P, Hannenhalli S. 2008. A tutorial of the poisson random field model in population genetics. Adv. Bioinforma. 2008:257864
    • (2008) Adv. Bioinforma. , vol.2008 , pp. 257864
    • Sethupathy, P.1    Hannenhalli, S.2
  • 125
    • 24644462173 scopus 로고    scopus 로고
    • Accurate multiplex polony sequencing of an evolved bacterial genome
    • Shendure J, Porreca GJ, Reppas NB, Lin X, McCutcheon JP, et al. 2005. Accurate multiplex polony sequencing of an evolved bacterial genome. Science 309:1728-32
    • (2005) Science , vol.309 , pp. 1728-1732
    • Shendure, J.1    Porreca, G.J.2    Reppas, N.B.3    Lin, X.4    McCutcheon, J.P.5
  • 126
    • 14844285310 scopus 로고    scopus 로고
    • The genomic distribution of population substructure in four populations using 8, 525 autosomal SNPs
    • Shriver MD, Kennedy GC, Parra EJ, Lawson HA, Sonpar V, et al. 2004. The genomic distribution of population substructure in four populations using 8, 525 autosomal SNPs. Hum. Genomics 1:274-86
    • (2004) Hum. Genomics , vol.1 , pp. 274-286
    • Shriver, M.D.1    Kennedy, G.C.2    Parra, E.J.3    Lawson, H.A.4    Sonpar, V.5
  • 127
    • 77954319663 scopus 로고    scopus 로고
    • Genetic evidence for high-altitude adaptation in Tibet
    • Simonson TS, Yang Y, Huff CD, Yun H, Qin G, et al. 2010. Genetic evidence for high-altitude adaptation in Tibet. Science 329:72-75
    • (2010) Science , vol.329 , pp. 72-75
    • Simonson, T.S.1    Yang, Y.2    Huff, C.D.3    Yun, H.4    Qin, G.5
  • 128
    • 0016220238 scopus 로고
    • The hitch-hiking effect of a favourable gene
    • Smith JM, Haigh J. 1974. The hitch-hiking effect of a favourable gene. Genet. Res. 23:23-35
    • (1974) Genet. Res. , vol.23 , pp. 23-35
    • Smith, J.M.1    Haigh, J.2
  • 129
    • 0027370038 scopus 로고
    • Population structure in Daphnia obtusa: Quantitative genetic and allozymic variation
    • Spitze K. 1993. Population structure in Daphnia obtusa: quantitative genetic and allozymic variation. Genetics 135:367-74
    • (1993) Genetics , vol.135 , pp. 367-374
    • Spitze, K.1
  • 132
    • 0024313579 scopus 로고
    • Statistical method for testing the neutral mutation hypothesis by DNA polymorphism
    • Tajima F. 1989. Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123:585-95
    • (1989) Genetics , vol.123 , pp. 585-595
    • Tajima, F.1
  • 133
  • 135
    • 0036856302 scopus 로고    scopus 로고
    • Mammalian sperm proteins are rapidly evolving: Evidence of positive selection in functionally diverse genes
    • Torgerson DG, Kulathinal RJ, Singh RS. 2002. Mammalian sperm proteins are rapidly evolving: evidence of positive selection in functionally diverse genes. Mol. Biol. Evol. 19:1973-80
    • (2002) Mol. Biol. Evol. , vol.19 , pp. 1973-1980
    • Torgerson, D.G.1    Kulathinal, R.J.2    Singh, R.S.3
  • 138
    • 84878149793 scopus 로고    scopus 로고
    • The impact of natural selection on health and disease: Uses of the population genetics approach in humans
    • Vasseur E, Quintana-Murci L. 2013. The impact of natural selection on health and disease: uses of the population genetics approach in humans. Evol. Appl. 6:596-607
    • (2013) Evol. Appl. , vol.6 , pp. 596-607
    • Vasseur, E.1    Quintana-Murci, L.2
  • 140
    • 4143144168 scopus 로고    scopus 로고
    • Signatures of selection and gene conversion associated with human color vision variation
    • Verrelli BC, Tishkoff SA. 2004. Signatures of selection and gene conversion associated with human color vision variation. Am. J. Hum. Genet. 75:363-75
    • (2004) Am. J. Hum. Genet. , vol.75 , pp. 363-375
    • Verrelli, B.C.1    Tishkoff, S.A.2
  • 142
    • 42049118301 scopus 로고    scopus 로고
    • Evolutionary inference from QST
    • Whitlock MC. 2008. Evolutionary inference from QST. Mol. Ecol. 17:1885-96
    • (2008) Mol. Ecol. , vol.17 , pp. 1885-1896
    • Whitlock, M.C.1
  • 143
    • 0034688140 scopus 로고    scopus 로고
    • Rapid evolution of male reproductive genes in the descent of man
    • Wyckoff GJ, Wang W, Wu CI. 2000. Rapid evolution of male reproductive genes in the descent of man. Nature 403:304-9
    • (2000) Nature , vol.403 , pp. 304-309
    • Wyckoff, G.J.1    Wang, W.2    Wu, C.I.3
  • 144
    • 34547803197 scopus 로고    scopus 로고
    • PAML 4: Phylogenetic analysis by maximum likelihood
    • Yang Z. 2007. PAML 4: phylogenetic analysis by maximum likelihood. Mol. Biol. Evol. 24:1586-91
    • (2007) Mol. Biol. Evol. , vol.24 , pp. 1586-1591
    • Yang, Z.1
  • 145
    • 0033639150 scopus 로고    scopus 로고
    • Statistical methods for detecting molecular adaptation
    • Yang Z, Bielawski JP. 2000. Statistical methods for detecting molecular adaptation. Trends Ecol. Evol. 15:496-503
    • (2000) Trends Ecol. Evol. , vol.15 , pp. 496-503
    • Yang, Z.1    Bielawski, J.P.2
  • 146
    • 0036270185 scopus 로고    scopus 로고
    • Codon-substitution models for detecting molecular adaptation at individual sites along specific lineages
    • Yang Z, Nielsen R. 2002. Codon-substitution models for detecting molecular adaptation at individual sites along specific lineages. Mol. Biol. Evol. 19:908-17
    • (2002) Mol. Biol. Evol. , vol.19 , pp. 908-917
    • Yang, Z.1    Nielsen, R.2
  • 147
    • 77954319020 scopus 로고    scopus 로고
    • Sequencing of 50 human exomes reveals adaptation to high altitude
    • Yi X, Liang Y, Huerta-Sanchez E, Jin X, Cuo ZX, et al. 2010. Sequencing of 50 human exomes reveals adaptation to high altitude. Science 329:75-78
    • (2010) Science , vol.329 , pp. 75-78
    • Yi, X.1    Liang, Y.2    Huerta-Sanchez, E.3    Jin, X.4    Cuo, Z.X.5
  • 148
    • 33751342650 scopus 로고    scopus 로고
    • Statistical tests for detecting positive selectionby utilizing high-frequency variants
    • Zeng K, Fu YX, Shi S, Wu CI. 2006. Statistical tests for detecting positive selectionby utilizing high-frequency variants. Genetics 174:1431-39
    • (2006) Genetics , vol.174 , pp. 1431-1439
    • Zeng, K.1    Fu, Y.X.2    Shi, S.3    Wu, C.I.4
  • 149
    • 0036959262 scopus 로고    scopus 로고
    • Accelerated protein evolution and origins of human-specific features: Foxp2 as an example
    • Zhang J, Webb DM, Podlaha O. 2002. Accelerated protein evolution and origins of human-specific features: Foxp2 as an example. Genetics 162:1825-35
    • (2002) Genetics , vol.162 , pp. 1825-1835
    • Zhang, J.1    Webb, D.M.2    Podlaha, O.3
  • 150
    • 27844543705 scopus 로고    scopus 로고
    • Human SNPs reveal no evidence of frequent positive selection
    • Zhang L, Li WH. 2005. Human SNPs reveal no evidence of frequent positive selection. Mol. Biol. Evol. 22:2504-7
    • (2005) Mol. Biol. Evol. , vol.22 , pp. 2504-2507
    • Zhang, L.1    Li, W.H.2


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