Using CRISPR/Cas to study gene function and model disease in vivo

FEBS Journal

Volumn , Issue , 2016, Pages 3194-3203

  Tschaharganeh, Darjus F ^a   Lowe, Scott W ^a,b   Garippa, Ralph J ^a   Livshits, Geulah ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

cancer; CRISPR Cas9; disease models; genome editing; mouse models

Indexed keywords

CRISPR ASSOCIATED PROTEIN; DNA; RNA; SHORT HAIRPIN RNA;

CHROMOSOME REARRANGEMENT; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DISEASE MODEL; DNA END JOINING REPAIR; EMBRYONIC STEM CELL; GENE ACTIVATION; GENE DELETION; GENE FUNCTION; GENE REPRESSION; GENETIC ENGINEERING; HOMOLOGOUS RECOMBINATION; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; REVIEW; RNA EDITING; RNA INTERFERENCE; TECHNOLOGY;

EID: 84986203154     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.13750     Document Type: Review

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