Efficient generation of gene-modified pigs via injection of zygote with Cas9/sgRNA

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Wang, Yong ^a   Du, Yinan ^b   Shen, Bin ^c   Zhou, Xiaoyang ^a   Li, Jian ^a   Liu, Yu ^a   Wang, Jianying ^c   Zhou, Jiankui ^b   Hu, Bian ^b   Kang, Nannan ^d   Gao, Jimin ^d   Yu, Liqing ^e   Huang, Xingxu ^b,f   Wei, Hong ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

^d WENZHOU MEDICAL UNIVERSITY   (China)

^e UNIVERSITY OF MARYLAND   (United States)

^f Shanghai Key Laboratory of Reproductive Medicine   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GUIDE RNA; MEMBRANE PROTEIN; MESSENGER RNA;

ALLELE; ANIMAL; ANTIBODY SPECIFICITY; CHEMISTRY; CRISPR CAS SYSTEM; FEMALE; GENE TARGETING; GENETICS; METABOLISM; MICROINJECTION; MOLECULAR GENETICS; MOSAICISM; NUCLEOTIDE SEQUENCE; OVARY; PIG; PROCEDURES; RNA EDITING; TRANSGENIC ANIMAL; ZYGOTE;

ALLELES; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; CRISPR-CAS SYSTEMS; FEMALE; GENE TARGETING; MEMBRANE PROTEINS; MICROINJECTIONS; MOLECULAR SEQUENCE DATA; MOSAICISM; ORGAN SPECIFICITY; OVARY; RNA EDITING; RNA, GUIDE; RNA, MESSENGER; SWINE; ZYGOTE;

EID: 84941208123     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep08256     Document Type: Article

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