The genetics of human infertility by functional interrogation of SNPs in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 33, 2015, Pages 10431-10436

  Singh, Priti ^a   Schimenti, John C ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

CRISPR Cas9; Cyclin; Genome editing; Meiosis; Spermatogenesis

Indexed keywords

PROTEIN KINASE; PROTEIN KINASE WEE1; UNCLASSIFIED DRUG; CDK2 PROTEIN, HUMAN; CDK2 PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE 2;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CRISPR CAS SYSTEM; FERTILITY; GENETIC ASSOCIATION; GENETIC LINKAGE; GENOME; HUMAN; HUMAN CELL; MALE; MALE INFERTILITY; MEIOSIS; MOUSE; NONHUMAN; ORTHOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SINGLE NUCLEOTIDE POLYMORPHISM; SPERMATOGONIUM; STEM CELL; ALGORITHM; ANIMAL; BINDING SITE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; FEMALE; FEMALE INFERTILITY; GENETIC VARIATION; GENETICS; MUTATION; PHOSPHORYLATION; PHYSIOLOGY; SPERMATOGENESIS; SPERMATOZOON; SPERMATOZOON COUNT;

MUS;

ALGORITHMS; ALLELES; ANIMALS; BINDING SITES; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CYCLIN-DEPENDENT KINASE 2; FEMALE; GENETIC VARIATION; HUMANS; INFERTILITY, FEMALE; INFERTILITY, MALE; MALE; MEIOSIS; MICE; MUTATION; PHENOTYPE; PHOSPHORYLATION; POLYMORPHISM, SINGLE NUCLEOTIDE; SPERM COUNT; SPERMATOGENESIS; SPERMATOZOA;

EID: 84940191254     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1506974112     Document Type: Article

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