Endonucleases: New tools to edit the mouse genome

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1842, Issue 10, 2014, Pages 1942-1950

  Wijshake, Tobias ^a   Baker, Darren J ^b   van de Sluis, Bart ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b Mayo Clinic   (United States)

Author keywords

CRISPR Cas; Endonucleases; Genome editing; Mouse; TALEN; ZFN

Indexed keywords

CRISPR ASSOCIATED PROTEIN; DNA BINDING PROTEIN; ENDONUCLEASE; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; ZINC FINGER NUCLEASE;

CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DNA MODIFICATION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EMBRYONIC STEM CELL; GENE DISRUPTION; GENE FUNCTION; GENE TARGETING; GENETIC ENGINEERING; GENETIC MANIPULATION; GENOME ANALYSIS; HOMOLOGOUS RECOMBINATION; HUMAN; NONHUMAN; PHASE 2 CLINICAL TRIAL (TOPIC); PROTEIN MODIFICATION; REVIEW; RNA SEQUENCE; TRANSGENICS;

EID: 84907257570     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.04.020     Document Type: Review

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