-
1
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas, S., Rand, M. D., & Lake, R. J. Notch signaling: cell fate control and signal integration in development. Science 284, 770-776 (1999
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
2
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
Bray, S. J. Notch signalling: a simple pathway becomes complex. Nat. Rev. Mol. Cell Biol. 7, 678-689 (2006
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 678-689
-
-
Bray, S.J.1
-
3
-
-
64249172203
-
The canonical Notch signaling pathway: Unfolding the activation mechanism
-
Kopan, R., & Ilagan, M. X. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137, 216-233 (2009
-
(2009)
Cell
, vol.137
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
4
-
-
84960494838
-
Notch signalling in the nucleus: Roles of Mastermind-like (MAML) transcriptional coactivators
-
Kitagawa, M. Notch signalling in the nucleus: roles of Mastermind-like (MAML) transcriptional coactivators. J. Biochem. 159, 287-294 (2016
-
(2016)
J. Biochem
, vol.159
, pp. 287-294
-
-
Kitagawa, M.1
-
5
-
-
0030597511
-
Pattern formation by lateral inhibition with feedback: A mathematical model of δ-notch intercellular signalling
-
Collier, J. R., Monk, N. A., Maini, P. K., & Lewis, J. H. Pattern formation by lateral inhibition with feedback: a mathematical model of δ-notch intercellular signalling. J. Theor. Biol. 183, 429-446 (1996
-
(1996)
J. Theor. Biol
, vol.183
, pp. 429-446
-
-
Collier, J.R.1
Monk, N.A.2
Maini, P.K.3
Lewis, J.H.4
-
6
-
-
79951810835
-
Targeting Notch signalling by the conserved miR 8/200 microRNA family in development and cancer cells
-
Vallejo, D. M., Caparros, E., & Dominguez, M. Targeting Notch signalling by the conserved miR 8/200 microRNA family in development and cancer cells. EMBO J. 30, 756-769 (2011
-
(2011)
EMBO J.
, vol.30
, pp. 756-769
-
-
Vallejo, D.M.1
Caparros, E.2
Dominguez, M.3
-
7
-
-
79951813950
-
The ZEB1/miR 200 feedback loop controls Notch signalling in cancer cells
-
Brabletz, S., et al. The ZEB1/miR 200 feedback loop controls Notch signalling in cancer cells. EMBO J. 30, 770-782 (2011
-
(2011)
EMBO J.
, vol.30
, pp. 770-782
-
-
Brabletz, S.1
-
8
-
-
0029093437
-
Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing drosophila wing
-
Kim, J., Irvine, K. D., & Carroll, S. B. Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell 82, 795-802 (1995
-
(1995)
Cell
, vol.82
, pp. 795-802
-
-
Kim, J.1
Irvine, K.D.2
Carroll, S.B.3
-
9
-
-
0842279817
-
Multiple signaling pathways and a selector protein sequentially regulate Drosophila wing development
-
Yan, S. J., Gu, Y., Li, W. X., & Fleming, R. J. Multiple signaling pathways and a selector protein sequentially regulate Drosophila wing development. Development 131, 285-298 (2004
-
(2004)
Development
, vol.131
, pp. 285-298
-
-
Yan, S.J.1
Gu, Y.2
Li, W.X.3
Fleming, R.J.4
-
10
-
-
84953390196
-
Oscillatory control of delta like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis
-
Shimojo, H., et al. Oscillatory control of Delta like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. Genes Dev. 30, 102-116 (2016
-
(2016)
Genes Dev
, vol.30
, pp. 102-116
-
-
Shimojo, H.1
-
11
-
-
84919362813
-
Spatiotemporal oscillations of Notch1 Dll1 and NICD are coordinated across the mouse PSM
-
Bone, R. A., et al. Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM. Development 141, 4806-4816 (2014
-
(2014)
Development
, vol.141
, pp. 4806-4816
-
-
Bone, R.A.1
-
12
-
-
84958117778
-
The many roles of Notch signaling during vertebrate somitogenesis
-
Wahi, K., Bochter, M. S., & Cole, S. E. The many roles of Notch signaling during vertebrate somitogenesis. Semin. Cell Dev. Biol. 49, 68-75 (2016
-
(2016)
Semin. Cell Dev. Biol
, vol.49
, pp. 68-75
-
-
Wahi, K.1
Bochter, M.S.2
Cole, S.E.3
-
13
-
-
33645758812
-
The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear
-
Kiernan, A. E., Xu, J., & Gridley, T. The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear. PLoS Genet. 2, e4 (2006
-
(2006)
Plos Genet
, vol.2
, pp. e4
-
-
Kiernan, A.E.1
Xu, J.2
Gridley, T.3
-
14
-
-
79951529175
-
Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: A mechanism for sensory organ specification
-
Neves, J., Parada, C., Chamizo, M., & Giraldez, F. Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification. Development 138, 735-744 (2011
-
(2011)
Development
, vol.138
, pp. 735-744
-
-
Neves, J.1
Parada, C.2
Chamizo, M.3
Giraldez, F.4
-
15
-
-
0032425547
-
Δ-Notch signalling and the patterning of sensory cell differentiation in the zebrafish ear: Evidence from the mind bomb mutant
-
Haddon, C., Jiang, Y. J., Smithers, L., & Lewis, J. δ-Notch signalling and the patterning of sensory cell differentiation in the zebrafish ear: evidence from the mind bomb mutant. Development 125, 4637-4644 (1998
-
(1998)
Development
, vol.125
, pp. 4637-4644
-
-
Haddon, C.1
Jiang, Y.J.2
Smithers, L.3
Lewis, J.4
-
16
-
-
33646164664
-
Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear
-
Brooker, R., Hozumi, K., & Lewis, J. Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear. Development 133, 1277-1286 (2006
-
(2006)
Development
, vol.133
, pp. 1277-1286
-
-
Brooker, R.1
Hozumi, K.2
Lewis, J.3
-
17
-
-
84872126418
-
Patterning and cell fate in the inner ear: A case for Notch in the chicken embryo
-
Neves, J., Abello, G., Petrovic, J., & Giraldez, F. Patterning and cell fate in the inner ear: a case for Notch in the chicken embryo. Dev. Growth Differ. 55, 96-112 (2013
-
(2013)
Dev. Growth Differ
, vol.55
, pp. 96-112
-
-
Neves, J.1
Abello, G.2
Petrovic, J.3
Giraldez, F.4
-
18
-
-
34347355519
-
Notch signalling is needed to maintain, but not to initiate, the formation of prosensory patches in the chick inner ear
-
Daudet, N., Ariza-McNaughton, L., & Lewis, J. Notch signalling is needed to maintain, but not to initiate, the formation of prosensory patches in the chick inner ear. Development 134, 2369-2378 (2007
-
(2007)
Development
, vol.134
, pp. 2369-2378
-
-
Daudet, N.1
Ariza-McNaughton, L.2
Lewis, J.3
-
19
-
-
84877143362
-
Notch as a hub for signaling in angiogenesis
-
Benedito, R., & Hellstrom, M. Notch as a hub for signaling in angiogenesis. Exp. Cell Res. 319, 1281-1288 (2013
-
(2013)
Exp. Cell Res
, vol.319
, pp. 1281-1288
-
-
Benedito, R.1
Hellstrom, M.2
-
20
-
-
33847046849
-
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
-
Hellstrom, M., et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature 445, 776-780 (2007
-
(2007)
Nature
, vol.445
, pp. 776-780
-
-
Hellstrom, M.1
-
21
-
-
84896706129
-
Alagille notch, and robustness: Why duplicating systems does not ensure redundancy
-
Kopan, R., Chen, S., & Liu, Z. Alagille, Notch, and robustness: why duplicating systems does not ensure redundancy. Pediatr. Nephrol. 29, 651-657 (2014
-
(2014)
Pediatr. Nephrol
, vol.29
, pp. 651-657
-
-
Kopan, R.1
Chen, S.2
Liu, Z.3
-
22
-
-
84923309385
-
Structural biology structural basis for notch1 engagement of delta-like 4
-
Luca, V. C., et al. Structural biology. Structural basis for Notch1 engagement of Delta-like 4. Science 347, 847-853 (2015
-
(2015)
Science
, vol.347
, pp. 847-853
-
-
Luca, V.C.1
-
23
-
-
84944404730
-
Notch signal strength controls cell fate in the haemogenic endothelium
-
Gama-Norton, L., et al. Notch signal strength controls cell fate in the haemogenic endothelium. Nat. Commun. 6, 8510 (2015
-
(2015)
Nat. Commun
, vol.6
, pp. 8510
-
-
Gama-Norton, L.1
-
24
-
-
84901387665
-
Ligand-dependent Notch signaling strength orchestrates lateral induction and lateral inhibition in the developing inner ear
-
Petrovic, J., et al. Ligand-dependent Notch signaling strength orchestrates lateral induction and lateral inhibition in the developing inner ear. Development 141, 2313-2324 (2014
-
(2014)
Development
, vol.141
, pp. 2313-2324
-
-
Petrovic, J.1
-
25
-
-
50849112357
-
Notch3: From subtle structural differences to functional diversity
-
Bellavia, D., et al. Notch3: from subtle structural differences to functional diversity. Oncogene 27, 5092-5098 (2008
-
(2008)
Oncogene
, vol.27
, pp. 5092-5098
-
-
Bellavia, D.1
-
26
-
-
84861969458
-
Notch signaling in human development and disease
-
Penton, A. L., Leonard, L. D., & Spinner, N. B. Notch signaling in human development and disease. Semin. Cell Dev. Biol. 23, 450-457 (2012
-
(2012)
Semin. Cell Dev. Biol
, vol.23
, pp. 450-457
-
-
Penton, A.L.1
Leonard, L.D.2
Spinner, N.B.3
-
27
-
-
7444224783
-
Notch1 and notch2 have opposite effects on embryonal brain tumor growth
-
Fan, X., et al. Notch1 and notch2 have opposite effects on embryonal brain tumor growth. Cancer Res. 64, 7787-7793 (2004
-
(2004)
Cancer Res
, vol.64
, pp. 7787-7793
-
-
Fan, X.1
-
28
-
-
84937831747
-
The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis
-
Liu, Z., et al. The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis. Development 142, 2452-2463 (2015
-
(2015)
Development
, vol.142
, pp. 2452-2463
-
-
Liu, Z.1
-
29
-
-
84879532571
-
The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development
-
Liu, Z., et al. The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development. Dev. Cell 25, 585-598 (2013
-
(2013)
Dev. Cell
, vol.25
, pp. 585-598
-
-
Liu, Z.1
-
30
-
-
79251523519
-
Mechanism and significance of cis-inhibition in Notch signalling
-
del Alamo, D., Rouault, H., & Schweisguth, F. Mechanism and significance of cis-inhibition in Notch signalling. Curr. Biol. 21, R40-R47 (2011
-
(2011)
Curr. Biol
, vol.21
, pp. R40-R47
-
-
Del Alamo, D.1
Rouault, H.2
Schweisguth, F.3
-
31
-
-
0030776397
-
Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing
-
de Celis, J. F., & Bray, S. Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing. Development 124, 3241-3251 (1997
-
(1997)
Development
, vol.124
, pp. 3241-3251
-
-
De Celis, J.F.1
Bray, S.2
-
32
-
-
0030918403
-
The function and regulation of cut expression on the wing margin of drosophila: Notch wingless and a dominant negative role for delta and serrate
-
Micchelli, C. A., Rulifson, E. J., & Blair, S. S. The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate. Development 124, 1485-1495 (1997
-
(1997)
Development
, vol.124
, pp. 1485-1495
-
-
Micchelli, C.A.1
Rulifson, E.J.2
Blair, S.S.3
-
33
-
-
77949484882
-
A role of receptor Notch in ligand cis-inhibition in Drosophila
-
Becam, I., Fiuza, U. M., Arias, A. M., & Milan, M. A role of receptor Notch in ligand cis-inhibition in Drosophila. Curr. Biol. 20, 554-560 (2010
-
(2010)
Curr. Biol
, vol.20
, pp. 554-560
-
-
Becam, I.1
Fiuza, U.M.2
Arias, A.M.3
Milan, M.4
-
34
-
-
33750202549
-
Role of conserved intracellular motifs in Serrate signalling. Cis-inhibition and endocytosis
-
Glittenberg, M., Pitsouli, C., Garvey, C., Delidakis, C., & Bray, S. Role of conserved intracellular motifs in Serrate signalling. cis-inhibition and endocytosis. EMBO J. 25, 4697-4706 (2006
-
(2006)
EMBO J.
, vol.25
, pp. 4697-4706
-
-
Glittenberg, M.1
Pitsouli, C.2
Garvey, C.3
Delidakis, C.4
Bray, S.5
-
35
-
-
77952092577
-
Cis-interactions between Notch and Delta generate mutually exclusive signalling states
-
Sprinzak, D., et al. Cis-interactions between Notch and Delta generate mutually exclusive signalling states. Nature 465, 86-90 (2010
-
(2010)
Nature
, vol.465
, pp. 86-90
-
-
Sprinzak, D.1
-
36
-
-
68849110194
-
Cis-Inhibition of Notch by endogenous Delta biases the outcome of lateral inhibition
-
Miller, A. C., Lyons, E. L., & Herman, T. G. cis-Inhibition of Notch by endogenous Delta biases the outcome of lateral inhibition. Curr. Biol. 19, 1378-1383 (2009
-
(2009)
Curr. Biol
, vol.19
, pp. 1378-1383
-
-
Miller, A.C.1
Lyons, E.L.2
Herman, T.G.3
-
37
-
-
84922352048
-
Jagged-delta asymmetry in notch signaling can give rise to a sender/receiver hybrid phenotype
-
Boareto, M., et al. Jagged-Delta asymmetry in Notch signaling can give rise to a Sender/Receiver hybrid phenotype. Proc. Natl Acad. Sci. USA 112, E402-E409 (2015
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. E402-E409
-
-
Boareto, M.1
-
38
-
-
84898669592
-
Notch4 reveals a novel mechanism regulating Notch signal transduction
-
James, A. C., et al. Notch4 reveals a novel mechanism regulating Notch signal transduction. Biochim. Biophys. Acta 1843, 1272-1284 (2014
-
(2014)
Biochim. Biophys. Acta
, vol.1843
, pp. 1272-1284
-
-
James, A.C.1
-
39
-
-
24944501849
-
The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands
-
Ladi, E., et al. The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands. J. Cell Biol. 170, 983-992 (2005
-
(2005)
J. Cell Biol
, vol.170
, pp. 983-992
-
-
Ladi, E.1
-
40
-
-
80051700630
-
A cell autonomous role for the notch ligand delta-like 3 in αβ T cell development
-
Hoyne, G. F., Chapman, G., Sontani, Y., Pursglove, S. E., & Dunwoodie, S. L. A cell autonomous role for the Notch ligand Delta-like 3 in αβ T cell development. Immunol. Cell Biol. 89, 696-705 (2011
-
(2011)
Immunol. Cell Biol
, vol.89
, pp. 696-705
-
-
Hoyne, G.F.1
Chapman, G.2
Sontani, Y.3
Pursglove, S.E.4
Dunwoodie, S.L.5
-
41
-
-
79551601837
-
Notch inhibition by the ligand Delta like 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis
-
Chapman, G., Sparrow, D. B., Kremmer, E., & Dunwoodie, S. L. Notch inhibition by the ligand Delta like 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis. Hum. Mol. Genet. 20, 905-916 (2011
-
(2011)
Hum. Mol. Genet
, vol.20
, pp. 905-916
-
-
Chapman, G.1
Sparrow, D.B.2
Kremmer, E.3
Dunwoodie, S.L.4
-
43
-
-
80053570445
-
Fringe benefits: Functional and structural impacts of O glycosylation on the extracellular domain of Notch receptors
-
Rana, N. A., & Haltiwanger, R. S. Fringe benefits: functional and structural impacts of O glycosylation on the extracellular domain of Notch receptors. Curr. Opin. Struct. Biol. 21, 583-589 (2011
-
(2011)
Curr. Opin. Struct. Biol
, vol.21
, pp. 583-589
-
-
Rana, N.A.1
Haltiwanger, R.S.2
-
44
-
-
12944255642
-
Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1
-
Yang, L. T., et al. Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1. Mol. Biol. Cell 16, 927-942 (2005
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 927-942
-
-
Yang, L.T.1
-
45
-
-
0030756962
-
Fringe modulates Notch-ligand interactions
-
Panin, V. M., Papayannopoulos, V., Wilson, R., & Irvine, K. D. Fringe modulates Notch-ligand interactions. Nature 387, 908-912 (1997
-
(1997)
Nature
, vol.387
, pp. 908-912
-
-
Panin, V.M.1
Papayannopoulos, V.2
Wilson, R.3
Irvine, K.D.4
-
46
-
-
0029960107
-
Delta is a ventral to dorsal signal complementary to serrate, another notch ligand, in drosophila wing formation
-
Doherty, D., Feger, G., Younger-Shepherd, S., Jan, L. Y., & Jan, Y. N. Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes Dev. 10, 421-434 (1996
-
(1996)
Genes Dev
, vol.10
, pp. 421-434
-
-
Doherty, D.1
Feger, G.2
Younger-Shepherd, S.3
Jan, L.Y.4
Jan, Y.N.5
-
47
-
-
66449123068
-
The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis
-
Benedito, R., et al. The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell 137, 1124-1135 (2009
-
(2009)
Cell
, vol.137
, pp. 1124-1135
-
-
Benedito, R.1
-
48
-
-
84951316975
-
Sequential Notch activation regulates ventricular chamber development
-
D'Amato, G., et al. Sequential Notch activation regulates ventricular chamber development. Nat. Cell Biol. 18, 7-20 (2016
-
(2016)
Nat. Cell Biol
, vol.18
, pp. 7-20
-
-
D'Amato, G.1
-
49
-
-
74349092354
-
Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression
-
Marklund, U., et al. Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression. Development 137, 437-445 (2010
-
(2010)
Development
, vol.137
, pp. 437-445
-
-
Marklund, U.1
-
50
-
-
84922373656
-
Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states
-
LeBon, L., Lee, T. V., Sprinzak, D., Jafar-Nejad, H., & Elowitz, M. B. Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states. eLife 3, e02950 (2014
-
(2014)
Elife
, vol.3
, pp. e02950
-
-
Le Bon, L.1
Lee, T.V.2
Sprinzak, D.3
Jafar-Nejad, H.4
Elowitz, M.B.5
-
51
-
-
0034051852
-
Ligand endocytosis drives receptor dissociation and activation in the Notch pathway
-
Parks, A. L., Klueg, K. M., Stout, J. R., & Muskavitch, M. A. Ligand endocytosis drives receptor dissociation and activation in the Notch pathway. Development 127, 1373-1385 (2000
-
(2000)
Development
, vol.127
, pp. 1373-1385
-
-
Parks, A.L.1
Klueg, K.M.2
Stout, J.R.3
Muskavitch, M.A.4
-
52
-
-
79960205452
-
Notch ligand ubiquitylation: What is it good for?
-
Weinmaster, G., & Fischer, J. A. Notch ligand ubiquitylation: what is it good for? Dev. Cell 21, 134-144 (2011
-
(2011)
Dev. Cell
, vol.21
, pp. 134-144
-
-
Weinmaster, G.1
Fischer, J.A.2
-
53
-
-
67949120665
-
Endocytic regulation of Notch signaling
-
Fortini, M. E., & Bilder, D. Endocytic regulation of Notch signaling. Curr. Opin. Genet. Dev. 19, 323-328 (2009
-
(2009)
Curr. Opin. Genet. Dev
, vol.19
, pp. 323-328
-
-
Fortini, M.E.1
Bilder, D.2
-
54
-
-
77956309044
-
Endocytosis and intracellular trafficking of Notch and its ligands
-
Yamamoto, S., Charng, W. L., & Bellen, H. J. Endocytosis and intracellular trafficking of Notch and its ligands. Curr. Top. Dev. Biol. 92, 165-200 (2010
-
(2010)
Curr. Top. Dev. Biol
, vol.92
, pp. 165-200
-
-
Yamamoto, S.1
Charng, W.L.2
Bellen, H.J.3
-
55
-
-
84862120880
-
Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin
-
Meloty-Kapella, L., Shergill, B., Kuon, J., Botvinick, E., & Weinmaster, G. Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin. Dev. Cell 22, 1299-1312 (2012
-
(2012)
Dev. Cell
, vol.22
, pp. 1299-1312
-
-
Meloty-Kapella, L.1
Shergill, B.2
Kuon, J.3
Botvinick, E.4
Weinmaster, G.5
-
56
-
-
34247189534
-
Structural basis for autoinhibition of Notch
-
Gordon, W. R., et al. Structural basis for autoinhibition of Notch. Nat. Struct. Mol. Biol. 14, 295-300 (2007
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 295-300
-
-
Gordon, W.R.1
-
57
-
-
84937638491
-
Mechanical allostery: Evidence for a force requirement in the proteolytic activation of Notch
-
Gordon, W. R., et al. Mechanical allostery: evidence for a force requirement in the proteolytic activation of Notch. Dev. Cell 33, 729-736 (2015
-
(2015)
Dev. Cell
, vol.33
, pp. 729-736
-
-
Gordon, W.R.1
-
58
-
-
21644462494
-
Distinct roles for mind bomb neuralized and epsin in mediating DSL endocytosis and signaling in drosophila
-
Wang, W., & Struhl, G. Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila. Development 132, 2883-2894 (2005
-
(2005)
Development
, vol.132
, pp. 2883-2894
-
-
Wang, W.1
Struhl, G.2
-
59
-
-
9544221645
-
Fat facets and liquid facets promote Delta endocytosis and Delta signaling in the signaling cells
-
Overstreet, E., Fitch, E., & Fischer, J. A. Fat facets and liquid facets promote Delta endocytosis and Delta signaling in the signaling cells. Development 131, 5355-5366 (2004
-
(2004)
Development
, vol.131
, pp. 5355-5366
-
-
Overstreet, E.1
Fitch, E.2
Fischer, J.A.3
-
60
-
-
18844429102
-
The ubiquitin ligase drosophila mind bomb promotes notch signaling by regulating the localization and activity of serrate and delta
-
Lai, E. C., Roegiers, F., Qin, X., Jan, Y. N., & Rubin, G. M. The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development 132, 2319-2332 (2005
-
(2005)
Development
, vol.132
, pp. 2319-2332
-
-
Lai, E.C.1
Roegiers, F.2
Qin, X.3
Jan, Y.N.4
Rubin, G.M.5
-
61
-
-
84855501946
-
Distinct intracellular motifs of Delta mediate its ubiquitylation and activation by Mindbomb1 and Neuralized
-
Daskalaki, A., et al. Distinct intracellular motifs of Delta mediate its ubiquitylation and activation by Mindbomb1 and Neuralized. J. Cell Biol. 195, 1017-1031 (2011
-
(2011)
J. Cell Biol
, vol.195
, pp. 1017-1031
-
-
Daskalaki, A.1
-
62
-
-
18844452750
-
Two distinct E3 ubiquitin ligases have complementary functions in the regulation of Delta and Serrate signaling in Drosophila
-
Le Borgne, R., Remaud, S., Hamel, S., & Schweisguth, F. Two distinct E3 ubiquitin ligases have complementary functions in the regulation of Delta and Serrate signaling in Drosophila. PLoS Biol. 3, e96 (2005
-
(2005)
Plos Biol
, vol.3
, pp. e96
-
-
Le Borgne, R.1
Remaud, S.2
Hamel, S.3
Schweisguth, F.4
-
63
-
-
69049088656
-
Both inhibition and activation of Notch signaling rely on a conserved Neuralized-binding motif in Bearded proteins and the Notch ligand Delta
-
Fontana, J. R., & Posakony, J. W. Both inhibition and activation of Notch signaling rely on a conserved Neuralized-binding motif in Bearded proteins and the Notch ligand Delta. Dev. Biol. 333, 373-385 (2009
-
(2009)
Dev. Biol
, vol.333
, pp. 373-385
-
-
Fontana, J.R.1
Posakony, J.W.2
-
64
-
-
43249100317
-
An obligatory role of Mind bomb 1 in Notch signaling of mammalian development
-
Koo, B. K., et al. An obligatory role of Mind bomb 1 in Notch signaling of mammalian development. PLoS ONE 2, e1221 (2007
-
(2007)
Plos One
, vol.2
, pp. e1221
-
-
Koo, B.K.1
-
65
-
-
0038686503
-
Unequal segregation of Neuralized biases Notch activation during asymmetric cell division
-
Le Borgne, R., & Schweisguth, F. Unequal segregation of Neuralized biases Notch activation during asymmetric cell division. Dev. Cell 5, 139-148 (2003
-
(2003)
Dev. Cell
, vol.5
, pp. 139-148
-
-
Le Borgne, R.1
Schweisguth, F.2
-
66
-
-
43449125262
-
Mind bomb 1 expressing intermediate progenitors generate notch signaling to maintain radial glial cells
-
Yoon, K. J., et al. Mind bomb 1 expressing intermediate progenitors generate notch signaling to maintain radial glial cells. Neuron 58, 519-531 (2008
-
(2008)
Neuron
, vol.58
, pp. 519-531
-
-
Yoon, K.J.1
-
67
-
-
84859650020
-
Intralineage directional Notch signaling regulates self renewal and differentiation of asymmetrically dividing radial glia
-
Dong, Z., Yang, N., Yeo, S. Y., Chitnis, A., & Guo, S. Intralineage directional Notch signaling regulates self renewal and differentiation of asymmetrically dividing radial glia. Neuron 74, 65-78 (2012
-
(2012)
Neuron
, vol.74
, pp. 65-78
-
-
Dong, Z.1
Yang, N.2
Yeo, S.Y.3
Chitnis, A.4
Guo, S.5
-
68
-
-
40849114907
-
Endosomal entry regulates Notch receptor activation in Drosophila melanogaster
-
Vaccari, T., Lu, H., Kanwar, R., Fortini, M. E., & Bilder, D. Endosomal entry regulates Notch receptor activation in Drosophila melanogaster. J. Cell Biol. 180, 755-762 (2008
-
(2008)
J. Cell Biol
, vol.180
, pp. 755-762
-
-
Vaccari, T.1
Lu, H.2
Kanwar, R.3
Fortini, M.E.4
Bilder, D.5
-
69
-
-
31944445720
-
Tumor suppressors: Control of signaling by endocytosis
-
Giebel, B., & Wodarz, A. Tumor suppressors: control of signaling by endocytosis. Curr. Biol. 16, R91-R92 (2006
-
(2006)
Curr. Biol
, vol.16
, pp. R91-R92
-
-
Giebel, B.1
Wodarz, A.2
-
70
-
-
27644498439
-
Tumor suppressor properties of the ESCRT II complex component Vps25 in Drosophila
-
Thompson, B. J., et al. Tumor suppressor properties of the ESCRT II complex component Vps25 in Drosophila. Dev. Cell 9, 711-720 (2005
-
(2005)
Dev. Cell
, vol.9
, pp. 711-720
-
-
Thompson, B.J.1
-
71
-
-
84858118267
-
The tumour suppressor Lethal 2) giant discs is required for the function of the ESCRT-III component Shrub/CHMP4
-
Troost, T., Jaeckel, S., Ohlenhard, N., & Klein, T. The tumour suppressor Lethal (2) giant discs is required for the function of the ESCRT-III component Shrub/CHMP4. J. Cell Sci. 125, 763-776 (2012
-
(2012)
J. Cell Sci
, vol.125
, pp. 763-776
-
-
Troost, T.1
Jaeckel, S.2
Ohlenhard, N.3
Klein, T.4
-
72
-
-
27644568520
-
The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating Notch trafficking
-
Vaccari, T., & Bilder, D. The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating Notch trafficking. Dev. Cell 9, 687-698 (2005
-
(2005)
Dev. Cell
, vol.9
, pp. 687-698
-
-
Vaccari, T.1
Bilder, D.2
-
73
-
-
33750530169
-
Itch/AIP 4 mediates Deltex degradation through the formation of K29 linked polyubiquitin chains
-
Chastagner, P., Israel, A., & Brou, C. Itch/AIP4 mediates Deltex degradation through the formation of K29 linked polyubiquitin chains. EMBO Rep. 7, 1147-1153 (2006
-
(2006)
EMBO Rep
, vol.7
, pp. 1147-1153
-
-
Chastagner, P.1
Israel, A.2
Brou, C.3
-
74
-
-
84855513161
-
Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal
-
Hori, K., Sen, A., Kirchhausen, T., & Artavanis-Tsakonas, S. Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal. J. Cell Biol. 195, 1005-1015 (2011
-
(2011)
J. Cell Biol
, vol.195
, pp. 1005-1015
-
-
Hori, K.1
Sen, A.2
Kirchhausen, T.3
Artavanis-Tsakonas, S.4
-
75
-
-
84901295370
-
Compensatory flux changes within an endocytic trafficking network maintain thermal robustness of Notch signaling
-
Shimizu, H., et al. Compensatory flux changes within an endocytic trafficking network maintain thermal robustness of Notch signaling. Cell 157, 1160-1174 (2014
-
(2014)
Cell
, vol.157
, pp. 1160-1174
-
-
Shimizu, H.1
-
76
-
-
84870158833
-
Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina
-
Kechad, A., et al. Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina. J. Neurosci. 32, 17197-17210 (2012
-
(2012)
J. Neurosci
, vol.32
, pp. 17197-17210
-
-
Kechad, A.1
-
77
-
-
0029909203
-
The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage
-
Frise, E., Knoblich, J. A., Younger-Shepherd, S., Jan, L. Y., & Jan, Y. N. The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage. Proc. Natl Acad. Sci. USA 93, 11925-11932 (1996
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 11925-11932
-
-
Frise, E.1
Knoblich, J.A.2
Younger-Shepherd, S.3
Jan, L.Y.4
Jan, Y.N.5
-
78
-
-
0030199995
-
Numb antagonizes Notch signaling to specify sibling neuron cell fates
-
Spana, E. P., & Doe, C. Q. Numb antagonizes Notch signaling to specify sibling neuron cell fates. Neuron 17, 21-26 (1996
-
(1996)
Neuron
, vol.17
, pp. 21-26
-
-
Spana, E.P.1
Doe, C.Q.2
-
79
-
-
0035799303
-
Multiple roles of mouse Numb in tuning developmental cell fates
-
Zilian, O., et al. Multiple roles of mouse Numb in tuning developmental cell fates. Curr. Biol. 11, 494-501 (2001
-
(2001)
Curr. Biol
, vol.11
, pp. 494-501
-
-
Zilian, O.1
-
80
-
-
73649114596
-
Lineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brain
-
Lin, S., et al. Lineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brain. Development 137, 43-51 (2010
-
(2010)
Development
, vol.137
, pp. 43-51
-
-
Lin, S.1
-
81
-
-
84865292942
-
Endocytosis and control of Notch signaling
-
Kandachar, V., & Roegiers, F. Endocytosis and control of Notch signaling. Curr. Opin. Cell Biol. 24, 534-540 (2012
-
(2012)
Curr. Opin. Cell Biol
, vol.24
, pp. 534-540
-
-
Kandachar, V.1
Roegiers, F.2
-
82
-
-
84876124240
-
Numb localizes at endosomes and controls the endosomal sorting of notch after asymmetric division in Drosophila
-
Couturier, L., Mazouni, K., & Schweisguth, F. Numb localizes at endosomes and controls the endosomal sorting of notch after asymmetric division in Drosophila. Curr. Biol. 23, 588-593 (2013
-
(2013)
Curr. Biol
, vol.23
, pp. 588-593
-
-
Couturier, L.1
Mazouni, K.2
Schweisguth, F.3
-
83
-
-
0042442453
-
Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila
-
O'Connor-Giles, K. M., & Skeath, J. B. Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila. Dev. Cell 5, 231-243 (2003
-
(2003)
Dev. Cell
, vol.5
, pp. 231-243
-
-
O'Connor-Giles, K.M.1
Skeath, J.B.2
-
84
-
-
30944462650
-
Numb and α-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs
-
Hutterer, A., & Knoblich, J. A. Numb and α-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs. EMBO Rep. 6, 836-842 (2005
-
(2005)
EMBO Rep
, vol.6
, pp. 836-842
-
-
Hutterer, A.1
Knoblich, J.A.2
-
85
-
-
84856426010
-
Endocytosis by Numb breaks Notch symmetry at cytokinesis
-
Couturier, L., Vodovar, N., & Schweisguth, F. Endocytosis by Numb breaks Notch symmetry at cytokinesis. Nat. Cell Biol. 14, 131-139 (2012
-
(2012)
Nat. Cell Biol
, vol.14
, pp. 131-139
-
-
Couturier, L.1
Vodovar, N.2
Schweisguth, F.3
-
86
-
-
67349204759
-
Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division
-
Coumailleau, F., Furthauer, M., Knoblich, J. A., & Gonzalez-Gaitan, M. Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division. Nature 458, 1051-1055 (2009
-
(2009)
Nature
, vol.458
, pp. 1051-1055
-
-
Coumailleau, F.1
Furthauer, M.2
Knoblich, J.A.3
Gonzalez-Gaitan, M.4
-
87
-
-
84923850274
-
Directional Notch trafficking in Sara endosomes during asymmetric cell division in the spinal cord
-
Kressmann, S., Campos, C., Castanon, I., Furthauer, M., & Gonzalez-Gaitan, M. Directional Notch trafficking in Sara endosomes during asymmetric cell division in the spinal cord. Nat. Cell Biol. 17, 333-339 (2015
-
(2015)
Nat. Cell Biol
, vol.17
, pp. 333-339
-
-
Kressmann, S.1
Campos, C.2
Castanon, I.3
Furthauer, M.4
Gonzalez-Gaitan, M.5
-
88
-
-
33645777828
-
Self-refinement of notch activity through the transmembrane protein crumbs: Modulation of γ-secretase activity
-
Herranz, H., Stamataki, E., Feiguin, F., & Milan, M. Self-refinement of Notch activity through the transmembrane protein Crumbs: modulation of γ-secretase activity. EMBO Rep. 7, 297-302 (2006
-
(2006)
EMBO Rep
, vol.7
, pp. 297-302
-
-
Herranz, H.1
Stamataki, E.2
Feiguin, F.3
Milan, M.4
-
89
-
-
84864000903
-
A Drosophila nephrin homolog, is required for presenilin-mediated Notch and APP-like cleavages
-
Singh, J., & Mlodzik, M. Hibris, a Drosophila nephrin homolog, is required for presenilin-mediated Notch and APP-like cleavages. Dev. Cell 23, 82-96 (2012
-
(2012)
Dev. Cell
, vol.23
, pp. 82-96
-
-
Singh, J.1
Hibris, M.M.2
-
90
-
-
84955337452
-
Quantitative analysis of Delta-like 1 membrane dynamics elucidates the role of contact geometry on Notch signaling
-
Khait, I., et al. Quantitative analysis of Delta-like 1 membrane dynamics elucidates the role of contact geometry on Notch signaling. Cell Rep. 14, 225-233 (2016
-
(2016)
Cell Rep
, vol.14
, pp. 225-233
-
-
Khait, I.1
-
91
-
-
77954891539
-
Dynamic filopodia transmit intermittent Delta-Notch signaling to drive pattern refinement during lateral inhibition
-
Cohen, M., Georgiou, M., Stevenson, N. L., Miodownik, M., & Baum, B. Dynamic filopodia transmit intermittent Delta-Notch signaling to drive pattern refinement during lateral inhibition. Dev. Cell 19, 78-89 (2010
-
(2010)
Dev. Cell
, vol.19
, pp. 78-89
-
-
Cohen, M.1
Georgiou, M.2
Stevenson, N.L.3
Miodownik, M.4
Baum, B.5
-
92
-
-
84930669089
-
Myoblast cytonemes mediate Wg signaling from the wing imaginal disc and Delta-Notch signaling to the air sac primordium
-
Huang, H., & Kornberg, T. B. Myoblast cytonemes mediate Wg signaling from the wing imaginal disc and Delta-Notch signaling to the air sac primordium. eLife 4, e06114 (2015
-
(2015)
Elife
, vol.4
, pp. e06114
-
-
Huang, H.1
Kornberg, T.B.2
-
93
-
-
84962592486
-
Long-distance communication by specialized cellular projections during pigment pattern development and evolution
-
Eom, D. S., Bain, E. J., Patterson, L. B., Grout, M. E., & Parichy, D. M. Long-distance communication by specialized cellular projections during pigment pattern development and evolution. eLife 4, e12401 (2015
-
(2015)
Elife
, vol.4
, pp. e12401
-
-
Eom, D.S.1
Bain, E.J.2
Patterson, L.B.3
Grout, M.E.4
Parichy, D.M.5
-
94
-
-
84891506641
-
Involvement of Delta/Notch signaling in zebrafish adult pigment stripe patterning
-
Hamada, H., et al. Involvement of Delta/Notch signaling in zebrafish adult pigment stripe patterning. Development 141, 318-324 (2014
-
(2014)
Development
, vol.141
, pp. 318-324
-
-
Hamada, H.1
-
95
-
-
84898760959
-
Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates
-
Hatakeyama, J., et al. Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates. Development 141, 1671-1682 (2014
-
(2014)
Development
, vol.141
, pp. 1671-1682
-
-
Hatakeyama, J.1
-
96
-
-
84859297815
-
Loss of llgl1 in retinal neuroepithelia reveals links between apical domain size notch activity and neurogenesis
-
Clark, B. S., et al. Loss of Llgl1 in retinal neuroepithelia reveals links between apical domain size, Notch activity and neurogenesis. Development 139, 1599-1610 (2012
-
(2012)
Development
, vol.139
, pp. 1599-1610
-
-
Clark, B.S.1
-
97
-
-
84906555139
-
Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling
-
Kobayashi, I., et al. Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling. Nature 512, 319-323 (2014
-
(2014)
Nature
, vol.512
, pp. 319-323
-
-
Kobayashi, I.1
-
98
-
-
79957594335
-
Neural crest regulates myogenesis through the transient activation of NOTCH
-
Rios, A. C., Serralbo, O., Salgado, D., & Marcelle, C. Neural crest regulates myogenesis through the transient activation of NOTCH. Nature 473, 532-535 (2011
-
(2011)
Nature
, vol.473
, pp. 532-535
-
-
Rios, A.C.1
Serralbo, O.2
Salgado, D.3
Marcelle, C.4
-
99
-
-
77957607057
-
Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting
-
Jakobsson, L., et al. Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting. Nat. Cell Biol. 12, 943-953 (2010
-
(2010)
Nat. Cell Biol
, vol.12
, pp. 943-953
-
-
Jakobsson, L.1
-
100
-
-
84877994081
-
Dynamic interactions between intermediate neurogenic progenitors and radial glia in embryonic mouse neocortex: Potential role in Dll1-Notch signaling
-
Nelson, B. R., Hodge, R. D., Bedogni, F., & Hevner, R. F. Dynamic interactions between intermediate neurogenic progenitors and radial glia in embryonic mouse neocortex: potential role in Dll1-Notch signaling. J. Neurosci. 33, 9122-9139 (2013
-
(2013)
J. Neurosci
, vol.33
, pp. 9122-9139
-
-
Nelson, B.R.1
Hodge, R.D.2
Bedogni, F.3
Hevner, R.F.4
-
101
-
-
84907331854
-
Temporal patterning of neuroblasts controls notch-mediated cell survival through regulation of hid or reaper
-
Bertet, C., et al. Temporal patterning of neuroblasts controls Notch-mediated cell survival through regulation of Hid or Reaper. Cell 158, 1173-1186 (2014
-
(2014)
Cell
, vol.158
, pp. 1173-1186
-
-
Bertet, C.1
-
102
-
-
0142259346
-
The role of notch in tumorigenesis: Oncogene or tumour suppressor?
-
Radtke, F., & Raj, K. The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat. Rev. Cancer 3, 756-767 (2003
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
103
-
-
84897470888
-
RBPJ the major transcriptional effector of Notch signaling, remains associated with chromatin throughout mitosis, suggesting a role in mitotic bookmarking
-
Lake, R. J., Tsai, P. F., Choi, I., Won, K. J., & Fan, H. Y. RBPJ, the major transcriptional effector of Notch signaling, remains associated with chromatin throughout mitosis, suggesting a role in mitotic bookmarking. PLoS Genet. 10, e1004204 (2014
-
(2014)
Plos Genet
, vol.10
, pp. e1004204
-
-
Lake, R.J.1
Tsai, P.F.2
Choi, I.3
Won, K.J.4
Fan, H.Y.5
-
104
-
-
84948564302
-
Chromatin signatures at Notch-regulated enhancers reveal large-scale changes in H3K56ac upon activation
-
Skalska, L., et al. Chromatin signatures at Notch-regulated enhancers reveal large-scale changes in H3K56ac upon activation. EMBO J. 34, 1889-1904 (2015
-
(2015)
EMBO J.
, vol.34
, pp. 1889-1904
-
-
Skalska, L.1
-
105
-
-
84892622973
-
NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers
-
Wang, H., et al. NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers. Proc. Natl Acad. Sci. USA 111, 705-710 (2014
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 705-710
-
-
Wang, H.1
-
106
-
-
84911909070
-
Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia
-
Yashiro-Ohtani, Y., et al. Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia. Proc. Natl Acad. Sci. USA 111, E4946-E4953 (2014
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. E4946-E4953
-
-
Yashiro-Ohtani, Y.1
-
107
-
-
84856747744
-
Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia
-
Ntziachristos, P., et al. Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia. Nat. Med. 18, 298-301 (2012
-
(2012)
Nat. Med
, vol.18
, pp. 298-301
-
-
Ntziachristos, P.1
-
108
-
-
84940758333
-
SpDamID: Marking DNA bound by protein complexes identifies Notch-dimer responsive eEnhancers
-
Hass, M. R., et al. SpDamID: marking DNA bound by protein complexes identifies Notch-dimer responsive eEnhancers. Mol. Cell 59, 685-697 (2015
-
(2015)
Mol. Cell
, vol.59
, pp. 685-697
-
-
Hass, M.R.1
-
109
-
-
0032145527
-
A histone deacetylase corepressor complex regulates the Notch signal transduction pathway
-
Kao, H. Y., et al. A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes Dev. 12, 2269-2277 (1998
-
(1998)
Genes Dev
, vol.12
, pp. 2269-2277
-
-
Kao, H.Y.1
-
110
-
-
84891869570
-
Structure and function of the CSL KyoT2 corepressor complex: A negative regulator of Notch signaling
-
Collins, K. J., Yuan, Z., & Kovall, R. A. Structure and function of the CSL KyoT2 corepressor complex: a negative regulator of Notch signaling. Structure 22, 70-81 (2014
-
(2014)
Structure
, vol.22
, pp. 70-81
-
-
Collins, K.J.1
Yuan, Z.2
Kovall, R.A.3
-
111
-
-
79955429963
-
Transcriptional repression in the Notch pathway: Thermodynamic characterization of CSL-MINT (Msx2 interacting nuclear target protein) complexes
-
VanderWielen, B. D., Yuan, Z., Friedmann, D. R., & Kovall, R. A. Transcriptional repression in the Notch pathway: thermodynamic characterization of CSL-MINT (Msx2 interacting nuclear target protein) complexes. J. Biol. Chem. 286, 14892-14902 (2011
-
(2011)
J. Biol. Chem
, vol.286
, pp. 14892-14902
-
-
VanderWielen, B.D.1
Yuan, Z.2
Friedmann, D.R.3
Kovall, R.A.4
-
112
-
-
34249886282
-
Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers
-
Krejci, A., & Bray, S. Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers. Genes Dev. 21, 1322-1327 (2007
-
(2007)
Genes Dev
, vol.21
, pp. 1322-1327
-
-
Krejci, A.1
Bray, S.2
-
113
-
-
84877298041
-
Dynamic binding of RBPJ is determined by Notch signaling status
-
Castel, D., et al. Dynamic binding of RBPJ is determined by Notch signaling status. Genes Dev. 27, 1059-1071 (2013
-
(2013)
Genes Dev
, vol.27
, pp. 1059-1071
-
-
Castel, D.1
-
114
-
-
84873505356
-
Transcriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E(spl)/Hes genes
-
Housden, B. E., et al. Transcriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E(spl)/Hes genes. PLoS Genet. 9, e1003162 (2013
-
(2013)
Plos Genet
, vol.9
, pp. e1003162
-
-
Housden, B.E.1
-
115
-
-
84940589899
-
Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation
-
Procopio, M. G., et al. Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation. Nat. Cell Biol. 17, 1193-1204 (2015
-
(2015)
Nat. Cell Biol
, vol.17
, pp. 1193-1204
-
-
Procopio, M.G.1
-
116
-
-
84962774263
-
Loss of CSL unlocks a hypoxic response and enhanced tumor growth potential in breast cancer cells
-
Braune, E. B., et al. Loss of CSL unlocks a hypoxic response and enhanced tumor growth potential in breast cancer cells. Stem Cell Rep. 6, 643-651 (2016
-
(2016)
Stem Cell Rep
, vol.6
, pp. 643-651
-
-
Braune, E.B.1
-
117
-
-
79958037576
-
A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development
-
Mulligan, P., et al. A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development. Mol. Cell 42, 689-699 (2011
-
(2011)
Mol. Cell
, vol.42
, pp. 689-699
-
-
Mulligan, P.1
-
118
-
-
81355124085
-
Molecular analysis of the notch repressor-complex in Drosophila: Characterization of potential hairless binding sites on suppressor of hairless
-
Kurth, P., Preiss, A., Kovall, R. A., & Maier, D. Molecular analysis of the notch repressor-complex in Drosophila: characterization of potential hairless binding sites on suppressor of hairless. PLoS ONE 6, e27986 (2011
-
(2011)
Plos One
, vol.6
, pp. e27986
-
-
Kurth, P.1
Preiss, A.2
Kovall, R.A.3
Maier, D.4
-
119
-
-
67650660754
-
The Notch signaling pathway: Transcriptional regulation at Notch target genes
-
Borggrefe, T., & Oswald, F. The Notch signaling pathway: transcriptional regulation at Notch target genes. Cell. Mol. Life Sci. 66, 1631-1646 (2009
-
(2009)
Cell. Mol. Life Sci
, vol.66
, pp. 1631-1646
-
-
Borggrefe, T.1
Oswald, F.2
-
120
-
-
77956309916
-
Notch targets and their regulation
-
Bray, S., & Bernard, F. Notch targets and their regulation. Curr. Top. Dev. Biol. 92, 253-275 (2010
-
(2010)
Curr. Top. Dev. Biol
, vol.92
, pp. 253-275
-
-
Bray, S.1
Bernard, F.2
-
121
-
-
12544255544
-
DNA transcription code for cell specific gene activation by Notch signaling
-
Cave, J. W., Loh, F., Surpris, J. W., Xia, L., & Caudy, M. A. A. DNA transcription code for cell specific gene activation by Notch signaling. Curr. Biol. 15, 94-104 (2005
-
(2005)
Curr. Biol
, vol.15
, pp. 94-104
-
-
Cave, J.W.1
Loh, F.2
Surpris, J.W.3
Xia, L.4
Caudy, M.A.A.5
-
122
-
-
38348998670
-
Notch-GATA synergy promotes endoderm-specific expression of ref 1 in C elegans
-
Neves, A., English, K., & Priess, J. R. Notch-GATA synergy promotes endoderm-specific expression of ref 1 in C. elegans. Development 134, 4459-4468 (2007
-
(2007)
Development
, vol.134
, pp. 4459-4468
-
-
Neves, A.1
English, K.2
Priess, J.R.3
-
123
-
-
79958058411
-
Notch3 and canonical NF κb signaling pathways cooperatively regulate Foxp3 transcription
-
Barbarulo, A., et al. Notch3 and canonical NF κB signaling pathways cooperatively regulate Foxp3 transcription. J. Immunol. 186, 6199-6206 (2011
-
(2011)
J. Immunol
, vol.186
, pp. 6199-6206
-
-
Barbarulo, A.1
-
124
-
-
84873119292
-
Notch cooperates with Lozenge/Runx to lock haemocytes into a differentiation programme
-
Terriente-Felix, A., et al. Notch cooperates with Lozenge/Runx to lock haemocytes into a differentiation programme. Development 140, 926-937 (2013
-
(2013)
Development
, vol.140
, pp. 926-937
-
-
Terriente-Felix, A.1
-
125
-
-
84897129801
-
The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells
-
ra28
-
Geimer Le Lay, A. S., et al. The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells. Sci. Signal. 7, ra28 (2014
-
(2014)
Sci. Signal
, vol.7
-
-
Geimer Le Lay, A.S.1
-
126
-
-
57349122315
-
Ikaros represses the transcriptional response to Notch signaling in T cell development
-
Kleinmann, E., Geimer Le Lay, A. S., Sellars, M., Kastner, P., & Chan, S. Ikaros represses the transcriptional response to Notch signaling in T cell development. Mol. Cell. Biol. 28, 7465-7475 (2008
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 7465-7475
-
-
Kleinmann, E.1
Geimer Le Lay, A.S.2
Sellars, M.3
Kastner, P.4
Chan, S.5
-
127
-
-
84930575765
-
Activated Notch counteracts Ikaros tumor suppression in mouse and human T cell acute lymphoblastic leukemia
-
Witkowski, M. T., et al. Activated Notch counteracts Ikaros tumor suppression in mouse and human T cell acute lymphoblastic leukemia. Leukemia 29, 1301-1311 (2015
-
(2015)
Leukemia
, vol.29
, pp. 1301-1311
-
-
Witkowski, M.T.1
-
128
-
-
84875803406
-
Snail inhibits Notch1 intracellular domain mediated transcriptional activation via competing with MAML1
-
Kim, H. S., Jeong, H., Lim, S. O., & Jung, G. Snail inhibits Notch1 intracellular domain mediated transcriptional activation via competing with MAML1. Biochem. Biophys. Res. Commun. 433, 6-10 (2013
-
(2013)
Biochem. Biophys. Res. Commun
, vol.433
, pp. 6-10
-
-
Kim, H.S.1
Jeong, H.2
Lim, S.O.3
Jung, G.4
-
129
-
-
70450255162
-
RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells
-
Gao, J., et al. RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells. Exp. Cell Res. 316, 149-157 (2010
-
(2010)
Exp. Cell Res
, vol.316
, pp. 149-157
-
-
Gao, J.1
-
130
-
-
77950550446
-
BCL6 canalizes Notch-dependent transcription, excluding Mastermind like1 from selected target genes during left-right patterning
-
Sakano, D., et al. BCL6 canalizes Notch-dependent transcription, excluding Mastermind like1 from selected target genes during left-right patterning. Dev. Cell 18, 450-462 (2010
-
(2010)
Dev. Cell
, vol.18
, pp. 450-462
-
-
Sakano, D.1
-
131
-
-
84870565938
-
BCL6 controls neurogenesis through Sirt1 dependent epigenetic repression of selective Notch targets
-
Tiberi, L., et al. BCL6 controls neurogenesis through Sirt1 dependent epigenetic repression of selective Notch targets. Nat. Neurosci. 15, 1627-1635 (2012
-
(2012)
Nat. Neurosci
, vol.15
, pp. 1627-1635
-
-
Tiberi, L.1
-
132
-
-
84920387089
-
Common and distinct DNA-binding and regulatory activities of the BEN-solo transcription factor family
-
Dai, Q., et al. Common and distinct DNA-binding and regulatory activities of the BEN-solo transcription factor family. Genes Dev. 29, 48-62 (2013
-
(2013)
Genes Dev
, vol.29
, pp. 48-62
-
-
Dai, Q.1
-
133
-
-
84921683408
-
The role of epigenetic mechanisms in Notch signaling during development
-
Schwanbeck, R. The role of epigenetic mechanisms in Notch signaling during development. J. Cell. Physiol. 230, 969-981 (2015
-
(2015)
J. Cell. Physiol
, vol.230
, pp. 969-981
-
-
Schwanbeck, R.1
-
134
-
-
84856292325
-
Chromatin modification of Notch targets in olfactory receptor neuron diversification
-
Endo, K., et al. Chromatin modification of Notch targets in olfactory receptor neuron diversification. Nat. Neurosci. 15, 224-233 (2011
-
(2011)
Nat. Neurosci
, vol.15
, pp. 224-233
-
-
Endo, K.1
-
135
-
-
84955416407
-
Aging neural progenitors lose competence to respond to mitogenic Notch signaling
-
Farnsworth, D. R., Bayraktar, O. A., & Doe, C. Q. Aging neural progenitors lose competence to respond to mitogenic Notch signaling. Curr. Biol. 25, 3058-3068 (2015
-
(2015)
Curr. Biol
, vol.25
, pp. 3058-3068
-
-
Farnsworth, D.R.1
Bayraktar, O.A.2
Doe, C.Q.3
-
136
-
-
84910146191
-
Epigenetic modification at Notch responsive promoters blunts efficacy of inducing notch pathway reactivation after myocardial infarction
-
Felician, G., et al. Epigenetic modification at Notch responsive promoters blunts efficacy of inducing notch pathway reactivation after myocardial infarction. Circ. Res. 115, 636-649 (2014
-
(2014)
Circ. Res
, vol.115
, pp. 636-649
-
-
Felician, G.1
-
137
-
-
70349527902
-
Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling
-
Martinez, A. M., et al. Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling. Nat. Genet. 41, 1076-1082 (2009
-
(2009)
Nat. Genet
, vol.41
, pp. 1076-1082
-
-
Martinez, A.M.1
-
138
-
-
0345166971
-
Cross-talk between the Notch and TGF-β signaling pathways mediated by interaction of the Notch intracellular domain with Smad3
-
Blokzijl, A., et al. Cross-talk between the Notch and TGF-β signaling pathways mediated by interaction of the Notch intracellular domain with Smad3. J. Cell Biol. 163, 723-728 (2003
-
(2003)
J. Cell Biol
, vol.163
, pp. 723-728
-
-
Blokzijl, A.1
-
139
-
-
84940775012
-
Hippo signaling is required for Notch-dependent smooth muscle differentiation of neural crest
-
Manderfield, L. J., et al. Hippo signaling is required for Notch-dependent smooth muscle differentiation of neural crest. Development 142, 2962-2971 (2015
-
(2015)
Development
, vol.142
, pp. 2962-2971
-
-
Manderfield, L.J.1
-
140
-
-
34547780475
-
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
-
O'Neil, J., et al. FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors. J. Exp. Med. 204, 1813-1824 (2007
-
(2007)
J. Exp. Med
, vol.204
, pp. 1813-1824
-
-
O'Neil, J.1
-
141
-
-
0035929669
-
The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel 10 homolog
-
Oberg, C., et al. The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel 10 homolog. J. Biol. Chem. 276, 35847-35853 (2001
-
(2001)
J. Biol. Chem
, vol.276
, pp. 35847-35853
-
-
Oberg, C.1
-
142
-
-
8844229536
-
Mastermind recruits CycC: CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover
-
Fryer, C. J., White, J. B., & Jones, K. A. Mastermind recruits CycC: CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Mol. Cell 16, 509-520 (2004
-
(2004)
Mol. Cell
, vol.16
, pp. 509-520
-
-
Fryer, C.J.1
White, J.B.2
Jones, K.A.3
-
143
-
-
84942617442
-
Emerging roles for the FBXW7 ubiquitin ligase in leukemia and beyond
-
Kourtis, N., Strikoudis, A., & Aifantis, I. Emerging roles for the FBXW7 ubiquitin ligase in leukemia and beyond. Curr. Opin. Cell Biol. 37, 28-34 (2015
-
(2015)
Curr. Opin. Cell Biol
, vol.37
, pp. 28-34
-
-
Kourtis, N.1
Strikoudis, A.2
Aifantis, I.3
-
144
-
-
84873051970
-
The SCF Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator
-
Davis, M. A., et al. The SCF Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator. Genes Dev. 27, 151-156 (2013
-
(2013)
Genes Dev
, vol.27
, pp. 151-156
-
-
Davis, M.A.1
-
145
-
-
78049231370
-
Fbw7 controls neural stem cell differentiation and progenitor apoptosis via notch and c jun
-
Hoeck, J. D., et al. Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c Jun. Nat. Neurosci. 13, 1365-1372 (2010
-
(2010)
Nat. Neurosci
, vol.13
, pp. 1365-1372
-
-
Hoeck, J.D.1
-
146
-
-
1542409037
-
Defective cardiovascular development and elevated cyclin e and notch proteins in mice lacking the fbw7 f box protein
-
Tetzlaff, M. T., et al. Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F box protein. Proc. Natl Acad. Sci. USA 101, 3338-3345 (2004
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 3338-3345
-
-
Tetzlaff, M.T.1
-
147
-
-
79955926985
-
Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase
-
Guarani, V., et al. Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase. Nature 473, 234-238 (2011
-
(2011)
Nature
, vol.473
, pp. 234-238
-
-
Guarani, V.1
-
148
-
-
84925452191
-
Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response
-
ra30
-
Hein, K., et al. Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response. Sci. Signal. 8, ra30 (2015
-
(2015)
Sci. Signal
, vol.8
-
-
Hein, K.1
-
149
-
-
42149117769
-
Interaction with factor inhibiting HIF 1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways
-
Zheng, X., et al. Interaction with factor inhibiting HIF 1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways. Proc. Natl Acad. Sci. USA 105, 3368-3373 (2008
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 3368-3373
-
-
Zheng, X.1
-
150
-
-
0041856097
-
Phosphorylation by glycogen synthase kinase 3β down regulates notch activity, a link for notch and wnt pathways
-
Espinosa, L., Ingles-Esteve, J., Aguilera, C., & Bigas, A. Phosphorylation by glycogen synthase kinase 3β down regulates Notch activity, a link for Notch and Wnt pathways. J. Biol. Chem. 278, 32227-32235 (2003
-
(2003)
J. Biol. Chem
, vol.278
, pp. 32227-32235
-
-
Espinosa, L.1
Ingles-Esteve, J.2
Aguilera, C.3
Bigas, A.4
-
151
-
-
43549095900
-
Down-regulation of Notch-dependent transcription by Akt in vitro
-
Song, J., Park, S., Kim, M., & Shin, I. Down-regulation of Notch-dependent transcription by Akt in vitro. FEBS Lett. 582, 1693-1699 (2008
-
(2008)
FEBS Lett
, vol.582
, pp. 1693-1699
-
-
Song, J.1
Park, S.2
Kim, M.3
Shin, I.4
-
152
-
-
84962311197
-
Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized dishevelled
-
Mund, T., et al. Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled. Open Biol. 5, 150185 (2015
-
(2015)
Open Biol
, vol.5
, pp. 150185
-
-
Mund, T.1
-
153
-
-
84908314478
-
Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer
-
Jung, J. G., et al. Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer. PLoS Genet. 10, e1004751 (2014
-
(2014)
Plos Genet
, vol.10
, pp. e1004751
-
-
Jung, J.G.1
-
154
-
-
77649273214
-
Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex
-
Ishitani, T., et al. Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex. Nat. Cell Biol. 12, 278-285 (2010
-
(2010)
Nat. Cell Biol
, vol.12
, pp. 278-285
-
-
Ishitani, T.1
-
155
-
-
67649969527
-
Attenuation of notch signalling by the down-syndrome-associated kinase dyrk1a
-
Fernandez-Martinez, J., et al. Attenuation of Notch signalling by the Down-syndrome-associated kinase DYRK1A. J. Cell Sci. 122, 1574-1583 (2009
-
(2009)
J. Cell Sci
, vol.122
, pp. 1574-1583
-
-
Fernandez-Martinez, J.1
-
156
-
-
84949293913
-
The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways
-
Borggrefe, T., et al. The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways. Biochim. Biophys. Acta 1863, 303-313 (2016
-
(2016)
Biochim. Biophys. Acta
, vol.1863
, pp. 303-313
-
-
Borggrefe, T.1
-
157
-
-
84869096429
-
NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function
-
Yatim, A., et al. NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function. Mol. Cell 48, 445-458 (2012
-
(2012)
Mol. Cell
, vol.48
, pp. 445-458
-
-
Yatim, A.1
-
158
-
-
34547922380
-
Delta-Notch - And then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors
-
Fischer, A., & Gessler, M. Delta-Notch - and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors. Nucleic Acids Res. 35, 4583-4596 (2007
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 4583-4596
-
-
Fischer, A.1
Gessler, M.2
-
159
-
-
0034710916
-
Notch signaling in the development of the inner ear: Lessons from Drosophila
-
Eddison, M., Le Roux, I., & Lewis, J. Notch signaling in the development of the inner ear: lessons from Drosophila. Proc. Natl Acad. Sci. USA 97, 11692-11699 (2000
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 11692-11699
-
-
Eddison, M.1
Le Roux, I.2
Lewis, J.3
-
160
-
-
84872860419
-
Dissecting the mechanisms of Notch induced hyperplasia
-
Djiane, A., et al. Dissecting the mechanisms of Notch induced hyperplasia. EMBO J. 32, 60-71 (2013
-
(2013)
EMBO J.
, vol.32
, pp. 60-71
-
-
Djiane, A.1
-
161
-
-
34948908663
-
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T cell leukemia
-
Palomero, T., et al. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T cell leukemia. Nat. Med. 13, 1203-1210 (2007
-
(2007)
Nat. Med
, vol.13
, pp. 1203-1210
-
-
Palomero, T.1
-
162
-
-
84938510798
-
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis
-
Serra, H., et al. PTEN mediates Notch-dependent stalk cell arrest in angiogenesis. Nat. Commun. 6, 7935 (2015
-
(2015)
Nat. Commun
, vol.6
, pp. 7935
-
-
Serra, H.1
-
163
-
-
23944506654
-
The love-hate relationship between ras and notch
-
Sundaram, M. V. The love-hate relationship between Ras and Notch. Genes Dev. 19, 1825-1839 (2005
-
(2005)
Genes Dev
, vol.19
, pp. 1825-1839
-
-
Sundaram, M.V.1
-
164
-
-
0034730331
-
Combinatorial signaling in the specification of unique cell fates
-
Flores, G. V., et al. Combinatorial signaling in the specification of unique cell fates. Cell 103, 75-85 (2000
-
(2000)
Cell
, vol.103
, pp. 75-85
-
-
Flores, G.V.1
-
165
-
-
33750869046
-
Signal integration during development: Mechanisms of EGFR and notch pathway function and cross-talk
-
Doroquez, D. B., & Rebay, I. Signal integration during development: mechanisms of EGFR and Notch pathway function and cross-talk. Crit. Rev. Biochem. Mol. Biol. 41, 339-385 (2006
-
(2006)
Crit. Rev. Biochem. Mol. Biol
, vol.41
, pp. 339-385
-
-
Doroquez, D.B.1
Rebay, I.2
-
166
-
-
0442272485
-
Crosstalk between the EGFR and LIN 12/Notch pathways in C elegans vulval development
-
Yoo, A. S., Bais, C., & Greenwald, I. Crosstalk between the EGFR and LIN 12/Notch pathways in C. elegans vulval development. Science 303, 663-666 (2004
-
(2004)
Science
, vol.303
, pp. 663-666
-
-
Yoo, A.S.1
Bais, C.2
Greenwald, I.3
-
167
-
-
84904314069
-
Wnt some lose some: Transcriptional governance of stem cells by Wnt/β-catenin signaling
-
Lien, W. H., & Fuchs, E. Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling. Genes Dev. 28, 1517-1532 (2014
-
(2014)
Genes Dev
, vol.28
, pp. 1517-1532
-
-
Lien, W.H.1
Fuchs, E.2
-
168
-
-
49449094586
-
A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition
-
Cordle, J., et al. A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition. Nat. Struct. Mol. Biol. 15, 849-857 (2008
-
(2008)
Nat. Struct. Mol. Biol
, vol.15
, pp. 849-857
-
-
Cordle, J.1
-
169
-
-
84888422328
-
Structural analysis uncovers lipid-binding properties of Notch ligands
-
Chillakuri, C. R., et al. Structural analysis uncovers lipid-binding properties of Notch ligands. Cell Rep. 5, 861-867 (2013
-
(2013)
Cell Rep
, vol.5
, pp. 861-867
-
-
Chillakuri, C.R.1
-
170
-
-
71449113533
-
Metalloprotease ADAM10 is required for Notch1 site 2 cleavage
-
van Tetering, G., et al. Metalloprotease ADAM10 is required for Notch1 site 2 cleavage. J. Biol. Chem. 284, 31018-31027 (2009
-
(2009)
J. Biol. Chem
, vol.284
, pp. 31018-31027
-
-
Van Tetering, G.1
-
171
-
-
77956300942
-
Mechanistic insights into Notch receptor signaling from structural and biochemical studies
-
Kovall, R. A., & Blacklow, S. C. Mechanistic insights into Notch receptor signaling from structural and biochemical studies. Curr. Top. Dev. Biol. 92, 31-71 (2010
-
(2010)
Curr. Top. Dev. Biol
, vol.92
, pp. 31-71
-
-
Kovall, R.A.1
Blacklow, S.C.2
-
172
-
-
33644749306
-
Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes
-
Nam, Y., Sliz, P., Song, L., Aster, J. C., & Blacklow, S. C. Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. Cell 124, 973-983 (2006
-
(2006)
Cell
, vol.124
, pp. 973-983
-
-
Nam, Y.1
Sliz, P.2
Song, L.3
Aster, J.C.4
Blacklow, S.C.5
-
173
-
-
33644761961
-
Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA
-
Wilson, J. J., & Kovall, R. A. Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA. Cell 124, 985-996 (2006
-
(2006)
Cell
, vol.124
, pp. 985-996
-
-
Wilson, J.J.1
Kovall, R.A.2
-
174
-
-
84885172948
-
DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia
-
Lin, S., et al. DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia. Oncogene 32, 4845-4853 (2013
-
(2013)
Oncogene
, vol.32
, pp. 4845-4853
-
-
Lin, S.1
-
175
-
-
84874534749
-
RNA helicase Ddx5 and the noncoding RNA SRA act as coactivators in the Notch signaling pathway
-
Jung, C., Mittler, G., Oswald, F., & Borggrefe, T. RNA helicase Ddx5 and the noncoding RNA SRA act as coactivators in the Notch signaling pathway. Biochim. Biophys. Acta 1833, 1180-1189 (2013
-
(2013)
Biochim. Biophys. Acta
, vol.1833
, pp. 1180-1189
-
-
Jung, C.1
Mittler, G.2
Oswald, F.3
Borggrefe, T.4
-
176
-
-
84921673788
-
The role of Notch receptors in transcriptional regulation
-
Wang, H., Zang, C., Liu, X. S., & Aster, J. C. The role of Notch receptors in transcriptional regulation. J. Cell. Physiol. 230, 982-988 (2015
-
(2015)
J. Cell. Physiol
, vol.230
, pp. 982-988
-
-
Wang, H.1
Zang, C.2
Liu, X.S.3
Aster, J.C.4
-
177
-
-
84964314300
-
The progenitor state is maintained by lysine-specific demethylase 1 mediated epigenetic plasticity during Drosophila follicle cell development
-
Lee, M. C., & Spradling, A. C. The progenitor state is maintained by lysine-specific demethylase 1 mediated epigenetic plasticity during Drosophila follicle cell development. Genes Dev. 28, 2739-2749 (2014
-
(2014)
Genes Dev
, vol.28
, pp. 2739-2749
-
-
Lee, M.C.1
Spradling, A.C.2
-
178
-
-
77949366450
-
Histone demethylase KDM5A is an integral part of the core Notch-RBP J repressor complex
-
Liefke, R., et al. Histone demethylase KDM5A is an integral part of the core Notch-RBP J repressor complex. Genes Dev. 24, 590-601 (2010
-
(2010)
Genes Dev
, vol.24
, pp. 590-601
-
-
Liefke, R.1
-
179
-
-
34248171798
-
Hairless the ignored antagonist of the Notch signalling pathway
-
Maier, D. Hairless: the ignored antagonist of the Notch signalling pathway. Hereditas 143, 212-221 (2006
-
(2006)
Hereditas
, vol.143
, pp. 212-221
-
-
Maier, D.1
-
180
-
-
84907597133
-
Notch and Hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst
-
Rayon, T., et al. Notch and Hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst. Dev. Cell 30, 410-422 (2014
-
(2014)
Dev. Cell
, vol.30
, pp. 410-422
-
-
Rayon, T.1
-
181
-
-
84880356030
-
Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development
-
Sacilotto, N., et al. Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development. Proc. Natl Acad. Sci. USA 110, 11893-11898 (2013
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 11893-11898
-
-
Sacilotto, N.1
-
182
-
-
84918533766
-
Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch
-
Lopez-Arribillaga, E., et al. Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch. Development 142, 41-50 (2015
-
(2015)
Development
, vol.142
, pp. 41-50
-
-
Lopez-Arribillaga, E.1
|