-
2
-
-
18144426076
-
Radial glial cells defned and major intermediates between embryonic stem cells and CNS neurons
-
Götz, M. & Barde, Y.A. Radial glial cells defned and major intermediates between embryonic stem cells and CNS neurons. Neuron 46, 369-372 (2005).
-
(2005)
Neuron
, vol.46
, pp. 369-372
-
-
Götz, M.1
Barde, Y.A.2
-
3
-
-
33645334165
-
F-box proteins: The key to protein degradation
-
Ho, M.S., Tsai, P.I. & Chien, C.T. F-box proteins: the key to protein degradation. J. Biomed. Sci. 13, 181-191 (2006).
-
(2006)
J. Biomed. Sci.
, vol.13
, pp. 181-191
-
-
Ho, M.S.1
Tsai, P.I.2
Chien, C.T.3
-
4
-
-
38549086019
-
FBW7 ubiquitin ligase: A tumour suppressor at the crossroads of cell division, growth and differentiation
-
Welcker, M. & Clurman, B.E. FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat. Rev. Cancer 8, 83-93 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 83-93
-
-
Welcker, M.1
Clurman, B.E.2
-
5
-
-
53049097854
-
The Fbxw7/hCdc4 tumor suppressor in human cancer
-
Tan, Y., Sangfelt, O. & Spruck, C. The Fbxw7/hCdc4 tumor suppressor in human cancer. Cancer Lett. 271, 1-12 (2008).
-
(2008)
Cancer Lett.
, vol.271
, pp. 1-12
-
-
Tan, Y.1
Sangfelt, O.2
Spruck, C.3
-
6
-
-
25144491626
-
Tumor suppressor activities of the Fbw7 E3 ubiquitin ligase receptor
-
Fuchs, S.Y. Tumor suppressor activities of the Fbw7 E3 ubiquitin ligase receptor. Cancer Biol. Ther. 4, 506-508 (2005).
-
(2005)
Cancer Biol. Ther.
, vol.4
, pp. 506-508
-
-
Fuchs, S.Y.1
-
7
-
-
0032979438
-
Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation
-
Behrens, A., Sibilia, M. & Wagner, E.F. Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nat. Genet. 21, 326-329 (1999).
-
(1999)
Nat. Genet.
, vol.21
, pp. 326-329
-
-
Behrens, A.1
Sibilia, M.2
Wagner, E.F.3
-
8
-
-
23744466225
-
The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: Identifcation of the nuclear pore complex as a potential target of the JNK pathway
-
Besirli, C.G., Wagner, E.F. & Johnson, E.M. Jr. The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: identifcation of the nuclear pore complex as a potential target of the JNK pathway. J. Cell Biol. 170, 401-411 (2005).
-
(2005)
J. Cell Biol.
, vol.170
, pp. 401-411
-
-
Besirli, C.G.1
Wagner, E.F.2
Johnson Jr., E.M.3
-
9
-
-
3242730442
-
The AP-1 transcription factor c-Jun is required for effcient axonal regeneration
-
Raivich, G. et al. The AP-1 transcription factor c-Jun is required for effcient axonal regeneration. Neuron 43, 57-67 (2004).
-
(2004)
Neuron
, vol.43
, pp. 57-67
-
-
Raivich, G.1
-
10
-
-
43449125262
-
Mind bomb 1-expressing intermediate progenitors generate notch signaling to maintain radial glial cells
-
Yoon, K.J. et al. Mind bomb 1-expressing intermediate progenitors generate notch signaling to maintain radial glial cells. Neuron 58, 519-531 (2008).
-
(2008)
Neuron
, vol.58
, pp. 519-531
-
-
Yoon, K.J.1
-
11
-
-
34548825987
-
Differential Notch signalling distinguishes neural stem cells from intermediate progenitors
-
Mizutani, K., Yoon, K., Dang, L., Tokunaga, A. & Gaiano, N. Differential Notch signalling distinguishes neural stem cells from intermediate progenitors. Nature 449, 351-355 (2007).
-
(2007)
Nature
, vol.449
, pp. 351-355
-
-
Mizutani, K.1
Yoon, K.2
Dang, L.3
Tokunaga, A.4
Gaiano, N.5
-
12
-
-
50849139508
-
Regulation of neural progenitor cell development in the nervous system
-
Corbin, J.G. et al. Regulation of neural progenitor cell development in the nervous system. J. Neurochem. 106, 2272-2287 (2008).
-
(2008)
J. Neurochem.
, vol.106
, pp. 2272-2287
-
-
Corbin, J.G.1
-
13
-
-
22844440114
-
Notch signaling in the mammalian central nervous system: Insights from mouse mutants
-
Yoon, K. & Gaiano, N. Notch signaling in the mammalian central nervous system: insights from mouse mutants. Nat. Neurosci. 8, 709-715 (2005).
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 709-715
-
-
Yoon, K.1
Gaiano, N.2
-
14
-
-
1542409037
-
Defective cardiovascular development and elevated cyclin e and Notch proteins in mice lacking the Fbw7 F-box protein
-
Tetzlaff, M.T. et al. Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein. Proc. Natl. Acad. Sci. USA 101, 3338-3345 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3338-3345
-
-
Tetzlaff, M.T.1
-
15
-
-
1542364470
-
Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development
-
Tsunematsu, R. et al. Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development. J. Biol. Chem. 279, 9417-9423 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 9417-9423
-
-
Tsunematsu, R.1
-
16
-
-
33646493863
-
Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb
-
Kramer, E.R. et al. Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb. Neuron 50, 35-47 (2006).
-
(2006)
Neuron
, vol.50
, pp. 35-47
-
-
Kramer, E.R.1
-
17
-
-
0035173885
-
Characterization of CNS precursor subtypes and radial glia
-
Hartfuss, E., Galli, R., Heins, N. & Götz, M. Characterization of CNS precursor subtypes and radial glia. Dev. Biol. 229, 15-30 (2001).
-
(2001)
Dev. Biol.
, vol.229
, pp. 15-30
-
-
Hartfuss, E.1
Galli, R.2
Heins, N.3
Götz, M.4
-
18
-
-
18244382560
-
Neural stem cells and neurospheres-re-evaluating the relationship
-
Reynolds, B.A. & Rietze, R.L. Neural stem cells and neurospheres-re-evaluating the relationship. Nat. Methods 2, 333-336 (2005).
-
(2005)
Nat. Methods
, vol.2
, pp. 333-336
-
-
Reynolds, B.A.1
Rietze, R.L.2
-
19
-
-
1342275412
-
The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling
-
Nateri, A.S., Riera-Sans, L., Da Costa, C. & Behrens, A. The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling. Science 303, 1374-1378 (2004).
-
(2004)
Science
, vol.303
, pp. 1374-1378
-
-
Nateri, A.S.1
Riera-Sans, L.2
Da Costa, C.3
Behrens, A.4
-
20
-
-
0030998713
-
Induction of apoptosis by the transcription factor c-Jun
-
Bossy-Wetzel, E., Bakiri, L. & Yaniv, M. Induction of apoptosis by the transcription factor c-Jun. EMBO J. 16, 1695-1709 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 1695-1709
-
-
Bossy-Wetzel, E.1
Bakiri, L.2
Yaniv, M.3
-
21
-
-
0035049449
-
Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release
-
Whitfeld, J., Neame, S.J., Paquet, L., Bernard, O. & Ham, J. Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Neuron 29, 629-643 (2001).
-
(2001)
Neuron
, vol.29
, pp. 629-643
-
-
Whitfeld, J.1
Neame, S.J.2
Paquet, L.3
Bernard, O.4
Ham, J.5
-
22
-
-
35648958679
-
Dp5/HRK is a c-Jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons
-
Ma, C. et al. dp5/HRK is a c-Jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons. J. Biol. Chem. 282, 30901-30909 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 30901-30909
-
-
Ma, C.1
-
23
-
-
0024276523
-
The jun proto-oncogene is positively autoregulated by its product
-
Angel, P. , Hattori, K., Smeal, T. & Karin, M. The jun proto-oncogene is positively autoregulated by its product, Jun/AP1. Cell 55, 875-885 (1988).
-
(1988)
Jun/AP1. Cell
, vol.55
, pp. 875-885
-
-
Angel, P.1
Hattori, K.2
Smeal, T.3
Karin, M.4
-
24
-
-
0033697009
-
Radial glial identity is promoted by Notch1 signaling in the murine forebrain
-
Gaiano, N., Nye, J.S. & Fishell, G. Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron 26, 395-404 (2000).
-
(2000)
Neuron
, vol.26
, pp. 395-404
-
-
Gaiano, N.1
Nye, J.S.2
Fishell, G.3
-
25
-
-
18244386723
-
Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells
-
Anthony, T.E., Mason, H.A., Gridley, T., Fishell, G. & Heintz, N. Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells. Genes Dev. 19, 1028-1033 (2005).
-
(2005)
Genes Dev.
, vol.19
, pp. 1028-1033
-
-
Anthony, T.E.1
Mason, H.A.2
Gridley, T.3
Fishell, G.4
Heintz, N.5
-
26
-
-
0033136717
-
Defcient T cell fate specifcation in mice with an induced inactivation of Notch1
-
Radtke, F. et al. Defcient T cell fate specifcation in mice with an induced inactivation of Notch1. Immunity 10, 547-558 (1999).
-
(1999)
Immunity
, vol.10
, pp. 547-558
-
-
Radtke, F.1
-
27
-
-
0041355557
-
Notch and Presenilin: Regulated intramembrane proteolysis links development and degeneration
-
Selkoe, D. & Kopan, R. Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration. Annu. Rev. Neurosci. 26, 565-597 (2003).
-
(2003)
Annu. Rev. Neurosci.
, vol.26
, pp. 565-597
-
-
Selkoe, D.1
Kopan, R.2
-
28
-
-
1842527386
-
Radial glia serve as neuronal progenitors in all regions of the central nervous system
-
Anthony, T.E., Klein, C., Fishell, G. & Heintz, N. Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron 41, 881-890 (2004).
-
(2004)
Neuron
, vol.41
, pp. 881-890
-
-
Anthony, T.E.1
Klein, C.2
Fishell, G.3
Heintz, N.4
-
29
-
-
0038487662
-
Sequential signaling through Notch1 and erbB receptors mediates radial glia differentiation
-
Patten, B.A., Peyrin, J.M., Weinmaster, G. & Corfas, G. Sequential signaling through Notch1 and erbB receptors mediates radial glia differentiation. J. Neurosci. 23, 6132-6140 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 6132-6140
-
-
Patten, B.A.1
Peyrin, J.M.2
Weinmaster, G.3
Corfas, G.4
-
30
-
-
0036615741
-
C-Jun N-terminal protein kinase (JNK) 2/3 is specifcally activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons
-
Coffey, E.T. et al. c-Jun N-terminal protein kinase (JNK) 2/3 is specifcally activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons. J. Neurosci. 22, 4335-4345 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 4335-4345
-
-
Coffey, E.T.1
-
31
-
-
36048978128
-
Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death
-
Wang, X. et al. Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death. Mol. Cell. Biol. 27, 7935-7946 (2007).
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 7935-7946
-
-
Wang, X.1
-
32
-
-
0346037264
-
JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins
-
Chang, L., Jones, Y., Ellisman, M.H., Goldstein, L.S. & Karin, M. JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins. Dev. Cell 4, 521-533 (2003).
-
(2003)
Dev. Cell
, vol.4
, pp. 521-533
-
-
Chang, L.1
Jones, Y.2
Ellisman, M.H.3
Goldstein, L.S.4
Karin, M.5
-
33
-
-
0033561365
-
Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation
-
Ohtsuka, T. et al. Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation. EMBO J. 18, 2196-2207 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 2196-2207
-
-
Ohtsuka, T.1
-
34
-
-
0030933977
-
Conservation of the Notch signalling pathway in mammalian neurogenesis
-
de la Pompa, J.L. et al. Conservation of the Notch signalling pathway in mammalian neurogenesis. Development 124, 1139-1148 (1997).
-
(1997)
Development
, vol.124
, pp. 1139-1148
-
-
De La Pompa, J.L.1
-
35
-
-
34047125787
-
Transient inactivation of Notch signaling synchronizes differentiation of neural progenitor cells
-
Nelson, B.R., Hartman, B.H., Georgi, S.A., Lan, M.S. & Reh, T.A. Transient inactivation of Notch signaling synchronizes differentiation of neural progenitor cells. Dev. Biol. 304, 479-498 (2007).
-
(2007)
Dev. Biol.
, vol.304
, pp. 479-498
-
-
Nelson, B.R.1
Hartman, B.H.2
Georgi, S.A.3
Lan, M.S.4
Reh, T.A.5
-
36
-
-
0033917984
-
Glial cell fate specifcation modulated by the bHLH gene Hes5 in mouse retina
-
Hojo, M. et al. Glial cell fate specifcation modulated by the bHLH gene Hes5 in mouse retina. Development 127, 2515-2522 (2000).
-
(2000)
Development
, vol.127
, pp. 2515-2522
-
-
Hojo, M.1
-
37
-
-
45149123052
-
Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7
-
Thompson, B.J. et al. Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7. J. Exp. Med. 205, 1395-1408 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1395-1408
-
-
Thompson, B.J.1
-
38
-
-
10644269326
-
Fbxw7/Cdc4 is a p53-dependent, haploinsuffcient tumour suppressor gene
-
Mao, J.H. et al. Fbxw7/Cdc4 is a p53-dependent, haploinsuffcient tumour suppressor gene. Nature 432, 775-779 (2004).
-
(2004)
Nature
, vol.432
, pp. 775-779
-
-
Mao, J.H.1
-
39
-
-
6944227551
-
A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size
-
Welcker, M., Orian, A., Grim, J.E., Eisenman, R.N. & Clurman, B.E. A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size. Curr. Biol. 14, 1852-1857 (2004).
-
(2004)
Curr. Biol.
, vol.14
, pp. 1852-1857
-
-
Welcker, M.1
Orian, A.2
Grim, J.E.3
Eisenman, R.N.4
Clurman, B.E.5
-
41
-
-
33745508920
-
Ubiquitylation of cyclin e requires the sequential function of SCF complexes containing distinct hCdc4 isoforms
-
van Drogen, F. et al. Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms. Mol. Cell 23, 37-48 (2006).
-
(2006)
Mol. Cell
, vol.23
, pp. 37-48
-
-
Van Drogen, F.1
-
42
-
-
42149132696
-
Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL
-
Matsuoka, S. et al. Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL. Genes Dev. 22, 986-991 (2008).
-
(2008)
Genes Dev.
, vol.22
, pp. 986-991
-
-
Matsuoka, S.1
-
43
-
-
33746810161
-
Adherent neural stem (NS) cells from fetal and adult forebrain
-
Pollard, S.M., Conti, L., Sun, Y., Goffredo, D. & Smith, A. Adherent neural stem (NS) cells from fetal and adult forebrain. Cereb. Cortex 16 (suppl. 1): i112-i120 (2006).
-
(2006)
Cereb. Cortex
, vol.16
, Issue.SUPPL. 1
-
-
Pollard, S.M.1
Conti, L.2
Sun, Y.3
Goffredo, D.4
Smith, A.5
-
44
-
-
0037232631
-
Impaired intervertebral disc formation in the absence of Jun
-
Behrens, A. et al. Impaired intervertebral disc formation in the absence of Jun. Development 130, 103-109 (2003).
-
(2003)
Development
, vol.130
, pp. 103-109
-
-
Behrens, A.1
-
45
-
-
24644478136
-
Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development
-
Nateri, A.S., Spencer-Dene, B. & Behrens, A. Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development. Nature 437, 281-285 (2005).
-
(2005)
Nature
, vol.437
, pp. 281-285
-
-
Nateri, A.S.1
Spencer-Dene, B.2
Behrens, A.3
|