-
1
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
P.D. Adams, P.V. Afonine, G. Bunkóczi, V.B. Chen, I.W. Davis, N. Echols, J.J. Headd, L.W. Hung, G.J. Kapral, and R.W. Grosse-Kunstleve et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution Acta Crystallogr. D Biol. Crystallogr. 66 2010 213 221
-
(2010)
Acta Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
Afonine, P.V.2
Bunkóczi, G.3
Chen, V.B.4
Davis, I.W.5
Echols, N.6
Headd, J.J.7
Hung, L.W.8
Kapral, G.J.9
Grosse-Kunstleve, R.W.10
-
2
-
-
84864005158
-
Targeting the Notch pathway: Twists and turns on the road to rational therapeutics
-
J.C. Aster, and S.C. Blacklow Targeting the Notch pathway: twists and turns on the road to rational therapeutics J. Clin. Oncol. 30 2012 2418 2420
-
(2012)
J. Clin. Oncol.
, vol.30
, pp. 2418-2420
-
-
Aster, J.C.1
Blacklow, S.C.2
-
3
-
-
42449123135
-
The effects of conformational heterogeneity on the binding of the Notch intracellular domain to effector proteins: A case of biologically tuned disorder
-
A. Bertagna, D. Toptygin, L. Brand, and D. Barrick The effects of conformational heterogeneity on the binding of the Notch intracellular domain to effector proteins: a case of biologically tuned disorder Biochem. Soc. Trans. 36 2008 157 166
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 157-166
-
-
Bertagna, A.1
Toptygin, D.2
Brand, L.3
Barrick, D.4
-
4
-
-
67650660754
-
The Notch signaling pathway: Transcriptional regulation at Notch target genes
-
T. Borggrefe, and F. Oswald The Notch signaling pathway: transcriptional regulation at Notch target genes Cell. Mol. Life Sci. 66 2009 1631 1646
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 1631-1646
-
-
Borggrefe, T.1
Oswald, F.2
-
5
-
-
79955532721
-
Epstein-Barr virus nuclear protein 3C binds to the N-terminal (NTD) and beta trefoil domains (BTD) of RBP/CSL; Only the NTD interaction is essential for lymphoblastoid cell growth
-
M.A. Calderwood, S. Lee, A.M. Holthaus, S.C. Blacklow, E. Kieff, and E. Johannsen Epstein-Barr virus nuclear protein 3C binds to the N-terminal (NTD) and beta trefoil domains (BTD) of RBP/CSL; only the NTD interaction is essential for lymphoblastoid cell growth Virology 414 2011 19 25
-
(2011)
Virology
, vol.414
, pp. 19-25
-
-
Calderwood, M.A.1
Lee, S.2
Holthaus, A.M.3
Blacklow, S.C.4
Kieff, E.5
Johannsen, E.6
-
6
-
-
74549178560
-
MolProbity: All-atom structure validation for macromolecular crystallography
-
V.B. Chen, W.B. Arendall 3rd, J.J. Headd, D.A. Keedy, R.M. Immormino, G.J. Kapral, L.W. Murray, J.S. Richardson, and D.C. Richardson MolProbity: all-atom structure validation for macromolecular crystallography Acta Crystallogr. D Biol. Crystallogr. 66 2010 12 21
-
(2010)
Acta Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 12-21
-
-
Chen, V.B.1
Arendall III, W.B.2
Headd, J.J.3
Keedy, D.A.4
Immormino, R.M.5
Kapral, G.J.6
Murray, L.W.7
Richardson, J.S.8
Richardson, D.C.9
-
7
-
-
84863012561
-
Conformational locking upon cooperative assembly of notch transcription complexes
-
S.H. Choi, T.E. Wales, Y. Nam, D.J. O'Donovan, P. Sliz, J.R. Engen, and S.C. Blacklow Conformational locking upon cooperative assembly of notch transcription complexes Structure 20 2012 340 349
-
(2012)
Structure
, vol.20
, pp. 340-349
-
-
Choi, S.H.1
Wales, T.E.2
Nam, Y.3
O'Donovan, D.J.4
Sliz, P.5
Engen, J.R.6
Blacklow, S.C.7
-
9
-
-
75149112880
-
Thermodynamic and structural insights into CSL-DNA complexes
-
D.R. Friedmann, and R.A. Kovall Thermodynamic and structural insights into CSL-DNA complexes Protein Sci. 19 2010 34 46
-
(2010)
Protein Sci.
, vol.19
, pp. 34-46
-
-
Friedmann, D.R.1
Kovall, R.A.2
-
10
-
-
47249090444
-
RAM-induced allostery facilitates assembly of a notch pathway active transcription complex
-
D.R. Friedmann, J.J. Wilson, and R.A. Kovall RAM-induced allostery facilitates assembly of a notch pathway active transcription complex J. Biol. Chem. 283 2008 14781 14791
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 14781-14791
-
-
Friedmann, D.R.1
Wilson, J.J.2
Kovall, R.A.3
-
11
-
-
0035724485
-
Mutational analysis of the J recombination signal sequence binding protein (RBP-J)/Epstein-Barr virus nuclear antigen 2 (EBNA2) and RBP-J/Notch interaction
-
K.P. Fuchs, G. Bommer, E. Dumont, B. Christoph, M. Vidal, E. Kremmer, and B. Kempkes Mutational analysis of the J recombination signal sequence binding protein (RBP-J)/Epstein-Barr virus nuclear antigen 2 (EBNA2) and RBP-J/Notch interaction Eur. J. Biochem. 268 2001 4639 4646
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 4639-4646
-
-
Fuchs, K.P.1
Bommer, G.2
Dumont, E.3
Christoph, B.4
Vidal, M.5
Kremmer, E.6
Kempkes, B.7
-
12
-
-
0037390535
-
Notch signaling and inherited disease syndromes
-
T. Gridley Notch signaling and inherited disease syndromes Hum. Mol. Genet. 12 Spec No 1 2003 R9 R13
-
(2003)
Hum. Mol. Genet.
, vol.12
, Issue.SPEC NO 1
-
-
Gridley, T.1
-
13
-
-
78049508185
-
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 (vIRF4/K10) is a novel interaction partner of CSL/CBF1, the major downstream effector of Notch signaling
-
K. Heinzelmann, B.A. Scholz, A. Nowak, E. Fossum, E. Kremmer, J. Haas, R. Frank, and B. Kempkes Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 (vIRF4/K10) is a novel interaction partner of CSL/CBF1, the major downstream effector of Notch signaling J. Virol. 84 2010 12255 12264
-
(2010)
J. Virol.
, vol.84
, pp. 12255-12264
-
-
Heinzelmann, K.1
Scholz, B.A.2
Nowak, A.3
Fossum, E.4
Kremmer, E.5
Haas, J.6
Frank, R.7
Kempkes, B.8
-
14
-
-
0028988990
-
Masking of the CBF1/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA2
-
J.J. Hsieh, and S.D. Hayward Masking of the CBF1/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA2 Science 268 1995 560 563
-
(1995)
Science
, vol.268
, pp. 560-563
-
-
Hsieh, J.J.1
Hayward, S.D.2
-
15
-
-
0029085935
-
Signalling downstream of activated mammalian Notch
-
S. Jarriault, C. Brou, F. Logeat, E.H. Schroeter, R. Kopan, and A. Israel Signalling downstream of activated mammalian Notch Nature 377 1995 355 358
-
(1995)
Nature
, vol.377
, pp. 355-358
-
-
Jarriault, S.1
Brou, C.2
Logeat, F.3
Schroeter, E.H.4
Kopan, R.5
Israel, A.6
-
16
-
-
77949893098
-
Thermodynamic analysis of the CSL x Notch interaction: Distribution of binding energy of the Notch RAM region to the CSL beta-trefoil domain and the mode of competition with the viral transactivator EBNA2
-
S.E. Johnson, M.X. Ilagan, R. Kopan, and D. Barrick Thermodynamic analysis of the CSL x Notch interaction: distribution of binding energy of the Notch RAM region to the CSL beta-trefoil domain and the mode of competition with the viral transactivator EBNA2 J. Biol. Chem. 285 2010 6681 6692
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6681-6692
-
-
Johnson, S.E.1
Ilagan, M.X.2
Kopan, R.3
Barrick, D.4
-
17
-
-
77956306573
-
Notch signaling in solid tumors
-
U. Koch, and F. Radtke Notch signaling in solid tumors Curr. Top. Dev. Biol. 92 2010 411 455
-
(2010)
Curr. Top. Dev. Biol.
, vol.92
, pp. 411-455
-
-
Koch, U.1
Radtke, F.2
-
18
-
-
64249172203
-
The canonical Notch signaling pathway: Unfolding the activation mechanism
-
R. Kopan, and M.X. Ilagan The canonical Notch signaling pathway: unfolding the activation mechanism Cell 137 2009 216 233
-
(2009)
Cell
, vol.137
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
19
-
-
77956300942
-
Mechanistic insights into Notch receptor signaling from structural and biochemical studies
-
R.A. Kovall, and S.C. Blacklow Mechanistic insights into Notch receptor signaling from structural and biochemical studies Curr. Top. Dev. Biol. 92 2010 31 71
-
(2010)
Curr. Top. Dev. Biol.
, vol.92
, pp. 31-71
-
-
Kovall, R.A.1
Blacklow, S.C.2
-
20
-
-
4644317278
-
Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA
-
R.A. Kovall, and W.A. Hendrickson Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA EMBO J. 23 2004 3441 3451
-
(2004)
EMBO J.
, vol.23
, pp. 3441-3451
-
-
Kovall, R.A.1
Hendrickson, W.A.2
-
21
-
-
34249886282
-
Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers
-
A. Krejcí, and S. Bray Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers Genes Dev. 21 2007 1322 1327
-
(2007)
Genes Dev.
, vol.21
, pp. 1322-1327
-
-
Krejcí, A.1
Bray, S.2
-
22
-
-
34548232365
-
Inference of macromolecular assemblies from crystalline state
-
E. Krissinel, and K. Henrick Inference of macromolecular assemblies from crystalline state J. Mol. Biol. 372 2007 774 797
-
(2007)
J. Mol. Biol.
, vol.372
, pp. 774-797
-
-
Krissinel, E.1
Henrick, K.2
-
23
-
-
56049114427
-
KyoT3, an isoform of murine FHL1, associates with the transcription factor RBP-J and represses the RBP-J-mediated transactivation
-
L. Liang, H.W. Zhang, J. Liang, X.L. Niu, S.Z. Zhang, L. Feng, Y.M. Liang, and H. Han KyoT3, an isoform of murine FHL1, associates with the transcription factor RBP-J and represses the RBP-J-mediated transactivation Biochim. Biophys. Acta 1779 2008 805 810
-
(2008)
Biochim. Biophys. Acta
, vol.1779
, pp. 805-810
-
-
Liang, L.1
Zhang, H.W.2
Liang, J.3
Niu, X.L.4
Zhang, S.Z.5
Feng, L.6
Liang, Y.M.7
Han, H.8
-
24
-
-
0028855281
-
Contribution of conserved amino acids in mediating the interaction between EBNA2 and CBF1/RBPJk
-
P.D. Ling, and S.D. Hayward Contribution of conserved amino acids in mediating the interaction between EBNA2 and CBF1/RBPJk J. Virol. 69 1995 1944 1950
-
(1995)
J. Virol.
, vol.69
, pp. 1944-1950
-
-
Ling, P.D.1
Hayward, S.D.2
-
25
-
-
0033638223
-
Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast
-
E. Mossessova, and C.D. Lima Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast Mol. Cell 5 2000 865 876
-
(2000)
Mol. Cell
, vol.5
, pp. 865-876
-
-
Mossessova, E.1
Lima, C.D.2
-
26
-
-
33646203458
-
Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability
-
C.T. Ong, H.T. Cheng, L.W. Chang, T. Ohtsuka, R. Kageyama, G.D. Stormo, and R. Kopan Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability J. Biol. Chem. 281 2006 5106 5119
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 5106-5119
-
-
Ong, C.T.1
Cheng, H.T.2
Chang, L.W.3
Ohtsuka, T.4
Kageyama, R.5
Stormo, G.D.6
Kopan, R.7
-
27
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Z. Otwinowski, and W. Minor Processing of X-ray diffraction data collected in oscillation mode Methods Enzymol. 276 1997 307 326
-
(1997)
Methods Enzymol.
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
28
-
-
2542618360
-
RING1 inhibits transactivation of RBP-J by Notch through interaction with LIM protein KyoT2
-
H. Qin, J. Wang, Y. Liang, Y. Taniguchi, K. Tanigaki, and H. Han RING1 inhibits transactivation of RBP-J by Notch through interaction with LIM protein KyoT2 Nucleic Acids Res. 32 2004 1492 1501
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 1492-1501
-
-
Qin, H.1
Wang, J.2
Liang, Y.3
Taniguchi, Y.4
Tanigaki, K.5
Han, H.6
-
29
-
-
13844272947
-
The PcG protein HPC2 inhibits RBP-J-mediated transcription by interacting with LIM protein KyoT2
-
H. Qin, D. Du, Y. Zhu, J. Li, L. Feng, Y. Liang, and H. Han The PcG protein HPC2 inhibits RBP-J-mediated transcription by interacting with LIM protein KyoT2 FEBS Lett. 579 2005 1220 1226
-
(2005)
FEBS Lett.
, vol.579
, pp. 1220-1226
-
-
Qin, H.1
Du, D.2
Zhu, Y.3
Li, J.4
Feng, L.5
Liang, Y.6
Han, H.7
-
30
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
F. Radtke, A. Wilson, G. Stark, M. Bauer, J. van Meerwijk, H.R. MacDonald, and M. Aguet Deficient T cell fate specification in mice with an induced inactivation of Notch1 Immunity 10 1999 547 558
-
(1999)
Immunity
, vol.10
, pp. 547-558
-
-
Radtke, F.1
Wilson, A.2
Stark, G.3
Bauer, M.4
Van Meerwijk, J.5
MacDonald, H.R.6
Aguet, M.7
-
32
-
-
84860287260
-
Exploiting structure similarity in refinement: Automated NCS and target-structure restraints in BUSTER
-
O.S. Smart, T.O. Womack, C. Flensburg, P. Keller, W. Paciorek, A. Sharff, C. Vonrhein, and G. Bricogne Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER Acta Crystallogr. D Biol. Crystallogr. 68 2012 368 380
-
(2012)
Acta Crystallogr. D Biol. Crystallogr.
, vol.68
, pp. 368-380
-
-
Smart, O.S.1
Womack, T.O.2
Flensburg, C.3
Keller, P.4
Paciorek, W.5
Sharff, A.6
Vonrhein, C.7
Bricogne, G.8
-
34
-
-
14844294424
-
Protein production by auto-induction in high density shaking cultures
-
F.W. Studier Protein production by auto-induction in high density shaking cultures Protein Expr. Purif. 41 2005 207 234
-
(2005)
Protein Expr. Purif.
, vol.41
, pp. 207-234
-
-
Studier, F.W.1
-
35
-
-
0002638463
-
Heat capacity and entropy changes in processes involving proteins
-
J.M. Sturtevant Heat capacity and entropy changes in processes involving proteins Proc. Natl. Acad. Sci. USA 74 1977 2236 2240
-
(1977)
Proc. Natl. Acad. Sci. USA
, vol.74
, pp. 2236-2240
-
-
Sturtevant, J.M.1
-
36
-
-
77952556128
-
Reduced Notch signaling leads to renal cysts and papillary microadenomas
-
K. Surendran, M. Selassie, H. Liapis, H. Krigman, and R. Kopan Reduced Notch signaling leads to renal cysts and papillary microadenomas J. Am. Soc. Nephrol. 21 2010 819 832
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 819-832
-
-
Surendran, K.1
Selassie, M.2
Liapis, H.3
Krigman, H.4
Kopan, R.5
-
37
-
-
0028216808
-
Notch1 is essential for postimplantation development in mice
-
P.J. Swiatek, C.E. Lindsell, F.F. del Amo, G. Weinmaster, and T. Gridley Notch1 is essential for postimplantation development in mice Genes Dev. 8 1994 707 719
-
(1994)
Genes Dev.
, vol.8
, pp. 707-719
-
-
Swiatek, P.J.1
Lindsell, C.E.2
Del Amo, F.F.3
Weinmaster, G.4
Gridley, T.5
-
38
-
-
0029583607
-
Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)
-
K. Tamura, Y. Taniguchi, S. Minoguchi, T. Sakai, T. Tun, T. Furukawa, and T. Honjo Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H) Curr. Biol. 5 1995 1416 1423
-
(1995)
Curr. Biol.
, vol.5
, pp. 1416-1423
-
-
Tamura, K.1
Taniguchi, Y.2
Minoguchi, S.3
Sakai, T.4
Tun, T.5
Furukawa, T.6
Honjo, T.7
-
39
-
-
0031983193
-
LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein
-
Y. Taniguchi, T. Furukawa, T. Tun, H. Han, and T. Honjo LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein Mol. Cell. Biol. 18 1998 644 654
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 644-654
-
-
Taniguchi, Y.1
Furukawa, T.2
Tun, T.3
Han, H.4
Honjo, T.5
-
40
-
-
79955429963
-
Transcriptional repression in the Notch pathway: Thermodynamic characterization of CSL-MINT (Msx2-interacting nuclear target protein) complexes
-
B.D. VanderWielen, Z. Yuan, D.R. Friedmann, and R.A. Kovall Transcriptional repression in the Notch pathway: thermodynamic characterization of CSL-MINT (Msx2-interacting nuclear target protein) complexes J. Biol. Chem. 286 2011 14892 14902
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 14892-14902
-
-
Vanderwielen, B.D.1
Yuan, Z.2
Friedmann, D.R.3
Kovall, R.A.4
-
41
-
-
78650884303
-
RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J
-
S.A. Wacker, C. Alvarado, G. von Wichert, U. Knippschild, J. Wiedenmann, K. Clauss, G.U. Nienhaus, H. Hameister, B. Baumann, and T. Borggrefe et al. RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J EMBO J. 30 2011 43 56
-
(2011)
EMBO J.
, vol.30
, pp. 43-56
-
-
Wacker, S.A.1
Alvarado, C.2
Von Wichert, G.3
Knippschild, U.4
Wiedenmann, J.5
Clauss, K.6
Nienhaus, G.U.7
Hameister, H.8
Baumann, B.9
Borggrefe, T.10
-
42
-
-
3242877618
-
DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data
-
L. Whitmore, and B.A. Wallace DICHROWEB, an online server for protein secondary structure analyses from circular dichroism spectroscopic data Nucleic Acids Res. 32 Web Server issue 2004 W668 W673
-
(2004)
Nucleic Acids Res.
, vol.32
, Issue.WEB SERVER ISSUE
-
-
Whitmore, L.1
Wallace, B.A.2
-
43
-
-
33644761961
-
Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA
-
J.J. Wilson, and R.A. Kovall Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA Cell 124 2006 985 996
-
(2006)
Cell
, vol.124
, pp. 985-996
-
-
Wilson, J.J.1
Kovall, R.A.2
-
45
-
-
84867415859
-
Characterization of CSL (CBF-1, Su(H), Lag-1) mutants reveals differences in signaling mediated by Notch1 and Notch2
-
Z. Yuan, D.R. Friedmann, B.D. VanderWielen, K.J. Collins, and R.A. Kovall Characterization of CSL (CBF-1, Su(H), Lag-1) mutants reveals differences in signaling mediated by Notch1 and Notch2 J. Biol. Chem. 287 2012 34904 34916
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 34904-34916
-
-
Yuan, Z.1
Friedmann, D.R.2
Vanderwielen, B.D.3
Collins, K.J.4
Kovall, R.A.5
|