The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate

Development

Volumn 124, Issue 8, 1997, Pages 1485-1495

  Micchelli, Craig A ^a   Rulifson, Eric J ^a,b   Blair, Seth S ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

Cell signaling; cut; Delta; Disheveled shaggy zeste white 3; Drosophlia wing imaginal disc; Notch; Pattern formation; Serrate; Wingless

Indexed keywords

TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DROSOPHILA; FEEDBACK SYSTEM; GENE EXPRESSION REGULATION; HOMEOBOX; LIMB DEVELOPMENT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN;

ANIMALS; CALCIUM-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, DOMINANT; GENES, HOMEOBOX; HOMEODOMAIN PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTORS, NOTCH; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; WING;

ANIMALIA;

EID: 0030918403     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Artavanis-Tsakonas, S., Matsuno, K. and Fortini, M. E. (1995). Notch signaling. Science 268, 225-232.
2. Axelrod, J. D., Matsuno, K., Artavanis-Tsakonas, S. and Perrimon, N. (1996). Interaction between Wingless and Notch signaling pathways mediated by Dishevelled. Science 271, 1826-1832.
3. Baker, N. E. (1988a). Transcription of the segment polarity gene wingless in the imaginal discs of Drosophila, and the phenotype of a pupal-lethal wg mutant. Development 102, 489-497.
4. Baker, N. E. (1988b). Embryonic and imaginal requirements for wg, a segment polarity gene in Drosaphila. Dev. Biol. 125, 96-108.
5. Blair, S. S. (1992). shaggy (zeste-white 3) and the formation of supernumerary bristle precursors in the developing wing blade of Drosophila. Dev. Biol. 152, 263-278.
6. Blair, S. S. (1993). Mechanisms of compartment formation: evidence that non-proliferating cells do not play a critical role in defining the D/V lineage restriction in the developing wing of Drosophila. Development 119, 339-351.
7. Blair, S. S. (1994). A role for the segment polarity gene shaggy-zeste white 3 in the specification of regional identity in the developing wing of Drosophila. Dev. Biol. 162, 229-244.
8. Blair, S. S. (1995). Compartments and appendage development in Drosophila. BioEssays 17, 299-309.
9. Blochlinger, K., Bodmer, R., Jack, J., Jan, L. Y. and Jan, Y. N. (1988). Primary structure and expression of a product from cut, a locus involved in specifying sensory organ identity in Drosophila. Nature 333, 629-635.
10. Blochlinger, K., Bodmer, R., Jan, L. Y. and Jan, Y. N. (1990). Patterns of expression of Cut, a protein required for external sensory organ development, in wild-type and cut mutant Drosophila embryos. Genes Dev. 4, 1322-1331.
11. Blochlinger, K., Jan, L. Y. and Jan, Y. N. (1991). Transformation of sensory organ identity by ectopic expression of Cut in Drosophila. Genes Dev. 5, 1124-1135.
12. Blochlinger, K., Jan, L. Y. and Jan, Y. N. (1993). Postembryonic patterns of expression of Cut, a locus regulating sensory organ identity in Drosophila. Development 117, 441-450.
13. Bodmer, R., Barbel, S., Shepherd, S., Jack, J. W., Jan, L. Y. and Jan, Y. N. (1987). Transformation of sensory organ identity by mutations of the Cut locus of D. melanogaster. Cell 51, 293-307.
14. Campbell, S., Inamdar, M., Rodrigues, V., Raghavan, V., Palazzolo, M. and Chovnick, A. (1992). The scalloped gene encodes a novel, evolutionarily conserved transcription factor required for sensory organ differentiation in Drosophila. Genes Dev. 6, 367-379.
15. Couso, J. P., Bate, M. and Martinez Arias, A. (1993). A wingless-dependent polar coordinate system in Drosophila imaginal discs. Science 259, 484-489.
16. Couso, J. P., Bishop, S. and Martinez-Arias, A. (1994). The wingless signalling pathway and the patterning of the wing margin in Drosophila. Development 120, 621-636.
17. Couso, J. P., Knust, E. and Martinez Arias, A. (1995). Serrate and wingless cooperate to induce vestigial gene expression and wing formation in Drosophila. Curr. Biol. 5, 1437-1448.
18. de Celis, J. F. and Garcia-Bellido, A. (1994a). Roles of the Notch gene in Drosophila wing morphogenesis. Mech. Dev. 46, 109-122.
19. de Celis, J. F. and Garcia-Bellido, A. (1994b). Modifications of the Notch function by Abruptex mutations in Drosophila melanogaster. Genetics 136, 183-194.
20. de Celis, J. F., Garcia-Bellido, A. and Bray, S. J. (1996a). Activation and function of Notch at the dorso-ventral boundary of the wing imaginal disc. Development 122, 359-369.
21. de Celis, J. F., de Celis, J., Ligoxygakis, P., Preiss, A., Delidakis, C. and Bray, S. J. (1996b). Functional relationships between Notch. Su(H), and the bHLH genes of the E(spl) complex: the E(spl) genes mediate only a subset of Notch activities during imaginal development. Development 122, 2719-2728.
22. de la Concha, A., Dietrich, U., Weigel, D. and Campos-Ortega, J. A. (1988). Functional interactions of neurogenic genes of Drosophila melanogaster. Genetics 118, 499-508.
23. Diaz-Benjumea, F. J. and Cohen, S. M. (1995). Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing. Development 121, 4215-4225.
24. Doherty, D., Feger, G., Younger-Shepherd, S., Jan, L. Y and Jan, Y. N. (1996). Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes Dev. 10, 421-434.
25. Dorsett, D. (1993). Distance-independent inactivation of an enhancer by the suppressor of Hairy-wing DNA-binding protein of Drosophila. Genetics 134, 1135-1144.
26. Fehon, R. G., Kooh, P. J., Rebay, I., Regan, C. L., Xu, T., Muskavitch, M. A. and Artavanis-Tsakonas, S. (1990). Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell 61, 523-534.
27. Fehon, R. G., Johansen, K., Rebay, I. and Artavanis-Tsakonas, S. (1991). Complex cellular and subcellular regulation of Notch expression during embryonic and imaginal development of Drosophila: implications for Notch function. J. Cell Biol. 113, 657-669.
28. Hing, H. K., Sun, X. and Artavanis-Tsakonas, S. (1994). Modulation of wingless signaling by Notch in Drosophila. Mech. Dev. 47, 261-268.
29. Jack, J. W., Dorsett, D., DeLotto, Y. and Liu, S. (1991). Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distant enhancer. Development 113, 735-747.
30. Jack, J. and DeLotto, Y. (1992). Effect of wing scalloping mutations on cut expression and sense organ differentiation in the Drosophila wing margin. Genetics 131, 353-363.
31. Jonsson, F. and Knust, E. (1996). Distinct functions of the Drosophila genes Serrate and Delta revealed by ectopic expression during wing development. Dev. Genes Evol. 206, 91-101.
32. Kim, J., Irvine, K. D. and Carroll, S. B. (1995). Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell 82, 795-802 (1995).
33. Kim, J., Sebring, A.,Esch, J. J., Kraus, M. E., Vorwerk, K., Magee, J. and Carroll, S. B. (1996). Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene. Nature 382, 133-138.
34. Klingensmith, J. and Nusse, R. (1994). Signaling by wingless in Drosophila. Dev. Biol. 166, 396-414.
35. Klingensmith, J., Nusse, R. and Perrimon, N. (1994). The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. Genes Dev. 8, 118-130.
36. Kooh, P. J., Fehon, R. G. and Muskavitch, M. A. T. (1993). Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development. Development 117, 493-507(1993).
37. Lawrence, P. A. and Struhl, G. (1996). Morphogens, compartments, and pattern: lessons from Drosophila? Cell 85, 951-961.
38. Ludlow, C., Choy, R. and Blochlinger, K. (1996). Functional analysis of Drosophila and mammalian Cut proteins in flies. Dev. Biol. 178, 149-159.
39. Lundgren, S. E., Callahan, C. A., Thor, S. and Thomas, J. B. (1995). Control of neuronal pathway selection by the Drosophila LIM homeodomain gene apterous. Development 121, 1769-1773.
40. Morcillo, P., Rosen, C. and Dorsett, D. (1996). Genes regulating the remote wing margin enhancer in the Drosophila cut locus. Genetics 144, 1143-1154.
41. Mogila, V. A., Ladvishenko, A. B., Simonova, O. B. and Gerasimova, T. I. (1992). Intragenic suppression: Stalker, a retrovirus-like transposable element, can compensate for a deficiency at the cut locus of Drosophila melanogaster. Genetica 86, 305-311.
42. Neumann, C. J. and Cohen, S. M. (1996). A hierarchy of cross-regulation involving Notch, wingless, vestigial and cut organizes the dorsal/ventral axis of the Drosophila wing. Development 122, 3477-3485.
43. Ng, M., Diaz-Benjumea, F. J., Vincent, J.-P., Wu, J. and Cohen, S. M. (1996). Specification of the wing primordium in Drosophila. Nature 381, 316-319.
44. Noordermeer, J., Klingensmith, J., Perrimon, N. and Nusse, R. (1994). dishevelled and armadillo act in the wingless signalling pathway in Drosophila. Nature 367, 80-83.
45. Parody, T and Muskavitch, M. A. (1993). The pleiotropic function of Delta during postembryonic development of Drosophila melanogaster. Genetics 135, 527-539.
46. Phillips, R. G. and Whittle, J. R. S. (1993). wingless expression mediates determination of peripheral nervous system elements in late stages of Drosophila wing disc development. Development 118, 427-438.
47. Romani, S., Campuzano, S., Macagno, E. and Modolell, J. (1989). Expression of achaete and scute genes in Drosophila imaginal discs and their function in sensory organ formation. Genes Dev. 3, 997-1007.
48. Rulifson, E. J. and Blair, S. S. (1995). Notch regulates wingless expression and is not required for the reception of paracrine wingless signals during wing margin development in Drosophila. Development 121, 2813-2824.
49. Rulifson, E. J, Micchelli, C. A., Axelrod, J. D., Perrimon, N. and Blair, S. S. (1996). wingless refines its own expression domain on the Drosophila wing margin. Nature 384, 72-74.
50. J of Drosophila melanogaster. Wilhelm Roux Arch. EntwMech. Org. 178, 233-245.
51. ts, a conditional Notch lethal in Drosophila. Dev. Biol. 62, 432-446.
52. Siegfried, E., Chou, T-B. and Perrimon, N. (1992). wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate. Cell 71, 1167-1179.
53. Simpson, P., El Messal, M., Moscoso del Prado, J. and Ripoll, P. (1988). Stripes of positional homologies across the wing blade of Drosophila melanogaster. Development 103, 391-402.
54. Speicher, S. A., Thomas, U., Hinz, U. and Knust, E. (1994). The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: control of proliferation. Development 120, 535-544.
55. Sun, X. and Arvtavanis-Tskonas, S. (1996). The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands. Development 122, 2465-2474.
56. Theisen, H., Purcell, J., Bennett, M., Kansagara, D., Syed, A. and Marsh, J. L. (1994). dishevelled is required during wingless signaling to establish both cell polarity and cell identity. Development 120, 347-360.
57. Thomas, U., Speicher, S. A. and Knust, E. (1991). The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs. Development 111, 749-761.
58. D, a dominant allele of the Drosophila gene Serrate. Genetics 139, 203-213.
59. Williams, J. A., Paddock, S. W. and Carroll, S. B. (1993). Pattern formation in a secondary field: A hierarchy of regulatory genes subdivides the developing Drosophila wing disc into discrete sub-regions. Development 117, 571-584.
60. Williams, J. A., Paddock, S. W., Vorwerk, K. and Carroll, S. B. (1994). Organization of wing formation and induction of a wing-patterning gene at the dorsal/ventral compartment boundary. Nature 368, 299-305.