Loss of CSL Unlocks a Hypoxic Response and Enhanced Tumor Growth Potential in Breast Cancer Cells

Stem Cell Reports

Volumn 6, Issue 5, 2016, Pages 643-651

  Braune, Eike Benjamin ^a   Tsoi, Yat Long ^a   Phoon, Yee Peng ^a   Landor, Sebastian ^a,b   Silva Cascales, Helena ^a   Ramsköld, Daniel ^c   Deng, Qiaolin ^a   Lindqvist, Arne ^a   Lian, Xiaojun ^a   Sahlgren, Cecilia ^b   Jin, Shao Bo ^a   Lendahl, Urban ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ÅBO AKADEMI UNIVERSITY   (Finland)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Breast cancer; Mitosis; Notch signaling; Transcriptome; Xenograft

Indexed keywords

CSL PROTEIN; DNA BINDING PROTEIN; NOTCH RECEPTOR; UNCLASSIFIED DRUG; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE BINDING PROTEIN; RBPJ PROTEIN, HUMAN; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; CRISPR CAS SYSTEM; DNA SEQUENCE; FEMALE; HYPOXIC CELL; IN VIVO STUDY; MAMMARY GLAND FAT; MOUSE; NONHUMAN; POLYPLOIDY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT; UPREGULATION; WESTERN BLOTTING; ANIMAL; BREAST TUMOR; CANCER STEM CELL; CELL HYPOXIA; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MITOSIS; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CELL DIFFERENTIATION; CELL HYPOXIA; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE-BINDING PROTEIN; MICE; MITOSIS; NEOPLASTIC STEM CELLS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANSCRIPTOME; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84962774263     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2016.03.004     Document Type: Article

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