Notch3 Interactome Analysis Identified WWP2 as a Negative Regulator of Notch3 Signaling in Ovarian Cancer

PLoS Genetics

Volumn 10, Issue 10, 2014, Pages

  Jung, Jin Gyoung ^a   Stoeck, Alexander ^a   Guan, Bin ^a   Wu, Ren Chin ^a,b   Zhu, Heng ^a   Blackshaw, Seth ^a   Shih, Ie Ming ^a   Wang, Tian Li ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

LIGASE; MUTANT PROTEIN; NOTCH RECEPTOR; NOTCH3 RECEPTOR; PLATINUM; PROTEIN WWP2; PROTEOME; REGULATOR PROTEIN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN C; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; NOTCH3 PROTEIN, HUMAN; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE; WWP2 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER STEM CELL; CELL CYCLE ARREST; CELL POPULATION; ENDOSOME; FEMALE; GENE LOCUS; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; LYSOSOME; MOLECULAR MECHANICS; MOUSE; NONHUMAN; OVARY CANCER; OVARY CARCINOMA; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MICROARRAY; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; UBIQUITINATION; WILD TYPE; ANIMAL; BIOSYNTHESIS; CARCINOGENESIS; DRUG SCREENING; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; OVARY TUMOR; PATHOLOGY; PROTEOMICS; TUMOR CELL LINE;

ANIMALS; CARCINOGENESIS; CELL LINE, TUMOR; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; LYSOSOMES; MICE; OVARIAN NEOPLASMS; PROTEOMICS; RECEPTORS, NOTCH; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84908314478     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004751     Document Type: Article

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