Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 10, 2004, Pages 3338-3345

  Tetzlaff, Michael T ^a   Yu, Wei ^a,b   Li, Mamie ^b   Zhang, Pumin ^a   Finegold, Milton ^a   Mahon, Kathleen ^a   Harper, J Wade ^a   Schwartz, Robert J ^a,b   Elledge, Stephen J ^a,b,c  

^a TEXAS CHILDREN S HOSPITAL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN E; F BOX PROTEIN; FBW7 PROTEIN; HERP1 PROTEIN; HERP2 PROTEIN; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH4 RECEPTOR; PROTEIN; SEL 10 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HES 1; UBIQUITIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CAENORHABDITIS ELEGANS; CARCINOGENESIS; CARDIOVASCULAR SYSTEM; CARDIOVASCULAR SYSTEM DEVELOPMENT DEFECT; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DNA REPLICATION; EMBRYO; EMBRYO MORTALITY; EVOLUTIONARY HOMOLOGY; FBW7 GENE; GENE INACTIVATION; GENE MUTATION; GENETIC TRANSCRIPTION; HEART DEVELOPMENT; HEMATOPOIETIC SYSTEM; IN VIVO STUDY; MAMMAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN DOMAIN; PROTEIN METABOLISM; SIGNAL TRANSDUCTION; TROPHOBLAST; TUMOR SUPPRESSOR GENE;

ANIMALS; BASE SEQUENCE; CARDIOVASCULAR ABNORMALITIES; CYCLIN E; DNA, COMPLEMENTARY; F-BOX PROTEINS; FEMALE; FETAL DEATH; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE TARGETING; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLACENTA; PREGNANCY; PROTO-ONCOGENE PROTEINS; RECEPTOR, NOTCH1; RECEPTORS, CELL SURFACE; RECEPTORS, NOTCH; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 1542409037     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0307875101     Document Type: Article

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