메뉴 건너뛰기




Volumn 25, Issue 20, 2006, Pages 4697-4706

Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis

Author keywords

Drosophila; Endocytosis; Notch; Serrate; Ubiquitination

Indexed keywords

JAGGED1; MEMBRANE PROTEIN; MINDBOMB1 PROTEIN; NEURALIZED PROTEIN; UNCLASSIFIED DRUG;

EID: 33750202549     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601337     Document Type: Article
Times cited : (103)

References (47)
  • 1
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas S, Rand MD, Lake RJ (1999) Notch signaling: cell fate control and signal integration in development. Science 284: 770-776
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 2
    • 0038795645 scopus 로고    scopus 로고
    • Signals for sorting of transmembrane proteins to endosomes and lysosomes
    • Bonifacino JS, Traub LM (2003) Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu Rev Biochem 72: 395-447
    • (2003) Annu Rev Biochem , vol.72 , pp. 395-447
    • Bonifacino, J.S.1    Traub, L.M.2
  • 3
    • 1842332725 scopus 로고    scopus 로고
    • The carboxyl-terminal valine residues of proTGF alpha are required for its efficient maturation and intracellular routing
    • Briley GP, Hissong MA, Chiu ML, Lee DC (1997) The carboxyl-terminal valine residues of proTGF alpha are required for its efficient maturation and intracellular routing. Mol Biol Cell 8: 1619-1631
    • (1997) Mol Biol Cell , vol.8 , pp. 1619-1631
    • Briley, G.P.1    Hissong, M.A.2    Chiu, M.L.3    Lee, D.C.4
  • 4
    • 0242593940 scopus 로고    scopus 로고
    • Glycosyltransferase activity of fringe modulates Notch-Delta interactions
    • Bruckner K, Perez L, Clausen H, Cohen S (2000) Glycosyltransferase activity of fringe modulates Notch-Delta interactions. Nature 406: 411-415
    • (2000) Nature , vol.406 , pp. 411-415
    • Bruckner, K.1    Perez, L.2    Clausen, H.3    Cohen, S.4
  • 5
    • 0034657381 scopus 로고    scopus 로고
    • Spatially restricted factors cooperate with notch in the regulation of Enhancer of split genes
    • Cooper MT, Tyler DM, Furriols M, Chalkiadaki A, Delidakis C, Bray S (2000) Spatially restricted factors cooperate with notch in the regulation of Enhancer of split genes. Dev Biol 221: 390-403
    • (2000) Dev Biol , vol.221 , pp. 390-403
    • Cooper, M.T.1    Tyler, D.M.2    Furriols, M.3    Chalkiadaki, A.4    Delidakis, C.5    Bray, S.6
  • 6
    • 0030776397 scopus 로고    scopus 로고
    • Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing
    • de Celis JF, Bray S (1997) Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing. Development 124: 3241-3251
    • (1997) Development , vol.124 , pp. 3241-3251
    • De Celis, J.F.1    Bray, S.2
  • 7
    • 0030052457 scopus 로고    scopus 로고
    • Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc
    • de Celis JF, Garcia-Bellido A, Bray SJ (1996) Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc. Development 122: 359-369
    • (1996) Development , vol.122 , pp. 359-369
    • De Celis, J.F.1    Garcia-Bellido, A.2    Bray, S.J.3
  • 8
    • 0032417317 scopus 로고    scopus 로고
    • Notch signalling mediates segmentation of the Drosophila leg
    • de Celis JF, Tyler DM, de Celis J, Bray SJ (1998) Notch signalling mediates segmentation of the Drosophila leg. Development 125: 4617-4626
    • (1998) Development , vol.125 , pp. 4617-4626
    • De Celis, J.F.1    Tyler, D.M.2    De Celis, J.3    Bray, S.J.4
  • 10
    • 0032235397 scopus 로고    scopus 로고
    • Structural conservation of Notch receptors and ligands
    • Fleming RJ (1998) Structural conservation of Notch receptors and ligands. Semin Cell Dev Biol 9: 599-607
    • (1998) Semin Cell Dev Biol , vol.9 , pp. 599-607
    • Fleming, R.J.1
  • 11
    • 0030812755 scopus 로고    scopus 로고
    • Functional domains of LAG-2, a putative signaling ligand for LIN-12 and GLP-1 receptors in Caenorhabditis elegans
    • Henderson ST, Gao D, Christensen S, Kimble J (1997) Functional domains of LAG-2, a putative signaling ligand for LIN-12 and GLP-1 receptors in Caenorhabditis elegans. Mol Biol Cell 8: 1751-1762
    • (1997) Mol Biol Cell , vol.8 , pp. 1751-1762
    • Henderson, S.T.1    Gao, D.2    Christensen, S.3    Kimble, J.4
  • 12
    • 0033523278 scopus 로고    scopus 로고
    • Fringe, Notch, and making developmental boundaries
    • Irvine KD (1999) Fringe, Notch, and making developmental boundaries. Curr Opin Genet Dev 9: 434-441
    • (1999) Curr Opin Genet Dev , vol.9 , pp. 434-441
    • Irvine, K.D.1
  • 14
    • 0036963514 scopus 로고    scopus 로고
    • Cysteine-rich region of X-Serrate-1 is required for activation of Notch signaling in Xenopus primary neurogenesis
    • Kiyota T, Kinoshita T (2002) Cysteine-rich region of X-Serrate-1 is required for activation of Notch signaling in Xenopus primary neurogenesis. Int J Dev Biol 46: 1057-1060
    • (2002) Int J Dev Biol , vol.46 , pp. 1057-1060
    • Kiyota, T.1    Kinoshita, T.2
  • 15
    • 0031238781 scopus 로고    scopus 로고
    • An intrinsic dominant negative activity of serrate that is modulated during wing development in Drosophila
    • Klein T, Brennan K, Arias AM (1997) An intrinsic dominant negative activity of serrate that is modulated during wing development in Drosophila. Dev Biol 189: 123-134
    • (1997) Dev Biol , vol.189 , pp. 123-134
    • Klein, T.1    Brennan, K.2    Arias, A.M.3
  • 17
    • 0035651380 scopus 로고    scopus 로고
    • Drosophila Neuralized is a ubiquitin ligase that promotes the internalization and degradation of Delta
    • Lai EC, Deblandre GA, Kintner C, Rubin GM (2001) Drosophila Neuralized is a ubiquitin ligase that promotes the internalization and degradation of Delta. Dev Cell 1: 783-794
    • (2001) Dev Cell , vol.1 , pp. 783-794
    • Lai, E.C.1    Deblandre, G.A.2    Kintner, C.3    Rubin, G.M.4
  • 18
    • 18844429102 scopus 로고    scopus 로고
    • The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta
    • Lai EC, Roegiers F, Qin X, Jan YN, Rubin GM (2005) The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development 132: 2319-2332
    • (2005) Development , vol.132 , pp. 2319-2332
    • Lai, E.C.1    Roegiers, F.2    Qin, X.3    Jan, Y.N.4    Rubin, G.M.5
  • 19
    • 18844414504 scopus 로고    scopus 로고
    • The roles of receptor and ligand endocytosis in regulating Notch signaling
    • Le Borgne R, Bardin A, Schweisguth F (2005a) The roles of receptor and ligand endocytosis in regulating Notch signaling. Development 132: 1751-1762
    • (2005) Development , vol.132 , pp. 1751-1762
    • Le Borgne, R.1    Bardin, A.2    Schweisguth, F.3
  • 20
    • 18844452750 scopus 로고    scopus 로고
    • Two distinct E3 ubiquitin ligases have complementary functions in the regulation of Delta and Serrate signaling in Drosophila
    • Le Borgne R, Remaud S, Hamel S, Schweisguth F (2005b) Two distinct E3 ubiquitin ligases have complementary functions in the regulation of Delta and Serrate signaling in Drosophila. PLoS Biol 3: e96
    • (2005) PLoS Biol , vol.3
    • Le Borgne, R.1    Remaud, S.2    Hamel, S.3    Schweisguth, F.4
  • 21
    • 0035341376 scopus 로고    scopus 로고
    • Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development
    • Lee T, Luo L (2001) Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development. Trends Neurosci 24: 251-254
    • (2001) Trends Neurosci , vol.24 , pp. 251-254
    • Lee, T.1    Luo, L.2
  • 22
    • 2642556495 scopus 로고    scopus 로고
    • The roles of cis-inactivation by Notch ligands and of neuralized during eye and bristle patterning in Drosophila
    • Li Y, Baker NE (2004) The roles of cis-inactivation by Notch ligands and of neuralized during eye and bristle patterning in Drosophila. BMC Dev Biol 4: 5
    • (2004) BMC Dev Biol , vol.4 , pp. 5
    • Li, Y.1    Baker, N.E.2
  • 23
    • 0030918403 scopus 로고    scopus 로고
    • The function and regulation of Cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate
    • Micchelli CA, Rulifson EJ, Blair SS (1997) The function and regulation of Cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate. Development 124: 1485-1495
    • (1997) Development , vol.124 , pp. 1485-1495
    • Micchelli, C.A.1    Rulifson, E.J.2    Blair, S.S.3
  • 25
    • 0028670620 scopus 로고
    • Delta-Notch signaling and Drosophila cell fate choice
    • Muskavitch MA (1994) Delta-Notch signaling and Drosophila cell fate choice. Dev Biol 166: 415-430
    • (1994) Dev Biol , vol.166 , pp. 415-430
    • Muskavitch, M.A.1
  • 26
    • 27944445286 scopus 로고    scopus 로고
    • Hairless-mediated repression of notch target genes requires the combined activity of Groucho and CtBP corepressors
    • Nagel AC, Krejci A, Tenin G, Bravo-Patino A, Bray S, Maier D, Preiss A (2005) Hairless-mediated repression of notch target genes requires the combined activity of Groucho and CtBP corepressors. Mol Cell Biol 25: 10433-10441
    • (2005) Mol Cell Biol , vol.25 , pp. 10433-10441
    • Nagel, A.C.1    Krejci, A.2    Tenin, G.3    Bravo-Patino, A.4    Bray, S.5    Maier, D.6    Preiss, A.7
  • 27
    • 0029960417 scopus 로고    scopus 로고
    • A hierarchy of cross-regulation involving Notch, wingless, vestigial and cut organizes the dorsal/ventral axis of the Drosophila wing
    • Neumann CJ, Cohen SM (1996) A hierarchy of cross-regulation involving Notch, wingless, vestigial and cut organizes the dorsal/ventral axis of the Drosophila wing. Development 1222: 3477-3485
    • (1996) Development , vol.1222 , pp. 3477-3485
    • Neumann, C.J.1    Cohen, S.M.2
  • 28
    • 0141922141 scopus 로고    scopus 로고
    • Modulation of notch-ligand binding by protein O-fucosyltransferase 1 and fringe
    • Okajima T, Xu A, Irvine KD (2003) Modulation of notch-ligand binding by protein O-fucosyltransferase 1 and fringe. J Biol Chem 278: 42340-42345
    • (2003) J Biol Chem , vol.278 , pp. 42340-42345
    • Okajima, T.1    Xu, A.2    Irvine, K.D.3
  • 29
    • 9544221645 scopus 로고    scopus 로고
    • Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells
    • Overstreet E, Fitch E, Fischer JA (2004) Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells. Development 131: 5355-5366
    • (2004) Development , vol.131 , pp. 5355-5366
    • Overstreet, E.1    Fitch, E.2    Fischer, J.A.3
  • 30
    • 0034051852 scopus 로고    scopus 로고
    • Ligand endocytosis drives receptor dissociation and activation in the Notch pathway
    • Parks AL, Klueg KM, Stout JR, Muskavitch MA (2000) Ligand endocytosis drives receptor dissociation and activation in the Notch pathway. Development 127: 1373-1385
    • (2000) Development , vol.127 , pp. 1373-1385
    • Parks, A.L.1    Klueg, K.M.2    Stout, J.R.3    Muskavitch, M.A.4
  • 32
    • 27144558408 scopus 로고    scopus 로고
    • The interplay between DSL proteins and ubiquitin ligases in Notch signaling
    • Pitsouli C, Delidakis C (2005) The interplay between DSL proteins and ubiquitin ligases in Notch signaling. Development 132: 4041-4050
    • (2005) Development , vol.132 , pp. 4041-4050
    • Pitsouli, C.1    Delidakis, C.2
  • 33
    • 0037081076 scopus 로고    scopus 로고
    • Intracellular cell-autonomous association of Notch and its ligands: A novel mechanism of Notch signal modification
    • Sakamoto K, Ohara O, Takagi M, Takeda S, Katsube K (2002) Intracellular cell-autonomous association of Notch and its ligands: a novel mechanism of Notch signal modification. Dev Biol 241: 313-326
    • (2002) Dev Biol , vol.241 , pp. 313-326
    • Sakamoto, K.1    Ohara, O.2    Takagi, M.3    Takeda, S.4    Katsube, K.5
  • 34
    • 0034704132 scopus 로고    scopus 로고
    • Distinct reading of different structural determinants modulates the dileucine-mediated transport steps of the lysosomal membrane protein LIMPII and the insulin-sensitive glucose transporter GLUT4
    • Sandoval IV, Martinez-Arca S, Valdueza J, Palacios S, Holman GD (2000) Distinct reading of different structural determinants modulates the dileucine-mediated transport steps of the lysosomal membrane protein LIMPII and the insulin-sensitive glucose transporter GLUT4. J Biol Chem 275: 39874-39885
    • (2000) J Biol Chem , vol.275 , pp. 39874-39885
    • Sandoval, I.V.1    Martinez-Arca, S.2    Valdueza, J.3    Palacios, S.4    Holman, G.D.5
  • 35
    • 1242265691 scopus 로고    scopus 로고
    • Notch signaling activity
    • Schweisguth F (2004) Notch signaling activity. Curr Biol 14: R129-R138
    • (2004) Curr Biol , vol.14
    • Schweisguth, F.1
  • 36
    • 0034916230 scopus 로고    scopus 로고
    • PDZ domains and the organization of supramolecular complexes
    • Sheng M, Sala C (2001) PDZ domains and the organization of supramolecular complexes. Annu Rev Neurosci 24: 1-29
    • (2001) Annu Rev Neurosci , vol.24 , pp. 1-29
    • Sheng, M.1    Sala, C.2
  • 38
    • 0036469994 scopus 로고    scopus 로고
    • Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain
    • Shimizu K, Chiba S, Saito T, Takahashi T, Kumano K, Hamada Y, Hirai H (2002) Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain. EMBO J 21: 294-302
    • (2002) EMBO J , vol.21 , pp. 294-302
    • Shimizu, K.1    Chiba, S.2    Saito, T.3    Takahashi, T.4    Kumano, K.5    Hamada, Y.6    Hirai, H.7
  • 40
    • 0028348883 scopus 로고
    • The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: Control of cell proliferation
    • Speicher SA, Thomas U, Hinz U, Knust E (1994) The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: control of cell proliferation. Development 120: 535-544
    • (1994) Development , vol.120 , pp. 535-544
    • Speicher, S.A.1    Thomas, U.2    Hinz, U.3    Knust, E.4
  • 41
    • 0029813479 scopus 로고    scopus 로고
    • The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands
    • Sun X, Artavanis-Tsakonas S (1996) The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands. Development 122: 2465-2474
    • (1996) Development , vol.122 , pp. 2465-2474
    • Sun, X.1    Artavanis-Tsakonas, S.2
  • 42
    • 9444297354 scopus 로고    scopus 로고
    • Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch
    • Wang W, Struhl G (2004) Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch. Development 131: 5367-5380
    • (2004) Development , vol.131 , pp. 5367-5380
    • Wang, W.1    Struhl, G.2
  • 43
    • 21644462494 scopus 로고    scopus 로고
    • Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila
    • Wang W, Struhl G (2005) Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila. Development 132: 2883-2894
    • (2005) Development , vol.132 , pp. 2883-2894
    • Wang, W.1    Struhl, G.2
  • 44
    • 10344227676 scopus 로고    scopus 로고
    • Delta proteins and MAGI proteins: An interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebra-fish development
    • Wright GJ, Leslie JD, Ariza-McNaughton L, Lewis J (2004) Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebra-fish development. Development 131: 5659-5669
    • (2004) Development , vol.131 , pp. 5659-5669
    • Wright, G.J.1    Leslie, J.D.2    Ariza-McNaughton, L.3    Lewis, J.4
  • 45
    • 24044436824 scopus 로고    scopus 로고
    • Regions of Drosophila Notch that contribute to ligand binding and the modulatory influence of Fringe
    • Xu A, Lei L, Irvine KD (2005) Regions of Drosophila Notch that contribute to ligand binding and the modulatory influence of Fringe. J Biol Chem 280: 30158-30165
    • (2005) J Biol Chem , vol.280 , pp. 30158-30165
    • Xu, A.1    Lei, L.2    Irvine, K.D.3
  • 46
    • 0035975961 scopus 로고    scopus 로고
    • Neuralized functions as an E3 ubiquitin ligase during Drosophila development
    • Yeh E, Dermer M, Commisso C, Zhou L, McGlade CJ, Boulianne GL (2001) Neuralized functions as an E3 ubiquitin ligase during Drosophila development. Curr Biol 11: 1675-1679
    • (2001) Curr Biol , vol.11 , pp. 1675-1679
    • Yeh, E.1    Dermer, M.2    Commisso, C.3    Zhou, L.4    McGlade, C.J.5    Boulianne, G.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.