The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by tegulating Notch trafficking

Developmental Cell

Volumn 9, Issue 5, 2005, Pages 687-698

  Vaccari, Thomas ^a   Bilder, David ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; JANUS KINASE; LIGAND; NOTCH RECEPTOR; STAT PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL MUTANT; CELL PROLIFERATION; CELL STIMULATION; CELL TRANSFORMATION; CONTROLLED STUDY; DATA ANALYSIS; DROSOPHILA; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVITY; EPITHELIUM CELL; MITOGENICITY; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SECRETION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TISSUE TYPES; WILD TYPE;

ANIMALS; CELL PROLIFERATION; DROSOPHILA; DROSOPHILA PROTEINS; ENDOSOMES; GENE EXPRESSION REGULATION; MUTATION; PROTEIN TRANSPORT; RECEPTORS, NOTCH; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; METAZOA;

EID: 27644568520     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2005.09.019     Document Type: Article

References (72)

1. D. Amsen J.M. Blander G.R. Lee K. Tanigaki T. Honjo and R.A. Flavell Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells Cell 117 2004 515-526
2. S. Artavanis-Tsakonas M.D. Rand and R.J. Lake Notch signaling: Cell fate control and signal integration in development Science 284 1999 770-776
3. M. Babst A protein's final ESCRT Traffic 6 2005 2-9
4. M. Babst G. Odorizzi E.J. Estepa and S.D. Emr Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking Traffic 1 2000 248-258
5. M. Babst D.J. Katzmann E.J. Estepa-Sabal T. Meerloo and S.D. Emr Escrt-III: An endosome-associated heterooligomeric protein complex required for mvb sorting Dev. Cell 3 2002 271-282
6. M. Babst D.J. Katzmann W.B. Snyder B. Wendland and S.D. Emr Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body Dev. Cell 3 2002 283-289
7. E.A. Bach S. Vincent M.P. Zeidler and N. Perrimon A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway Genetics 165 2003 1149-1166
8. K.G. Bache C. Raiborg A. Mehlum and H. Stenmark STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes J. Biol. Chem. 278 2003 12513-12521
9. K.G. Bache T. Slagsvold and H. Stenmark Defective downregulation of receptor tyrosine kinases in cancer EMBO J. 23 2004 2707-2712
10. A.M. Bailey and J.W. Posakony Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity Genes Dev. 9 1995 2609-2622
11. H.J. Bellen R.W. Levis G. Liao Y. He J.W. Carlson G. Tsang M. Evans-Holm P.R. Hiesinger K.L. Schulze G.M. Rubin et al. The BDGP gene disruption project: Single transposon insertions associated with 40% of Drosophila genes Genetics 167 2004 761-781
12. D. Bilder Epithelial polarity and growth control: Links from the Drosophila neoplastic tumor suppressors Genes Dev. 18 2004 1909-1925
13. A.M. Brumby and H.E. Richardson scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila EMBO J. 22 2003 5769-5779
14. J.L. Chao Y.C. Tsai S.J. Chiu and Y.H. Sun Localized Notch signal acts through eyg and upd to promote global growth in Drosophila eye Development 131 2004 3839-3847
15. L.M. Coussens and Z. Werb Inflammation and cancer Nature 420 2002 860-867
16. M.E. Fortini γ-secretase-mediated proteolysis in cell-surface-receptor signalling Nat. Rev. Mol. Cell Biol. 3 2002 673-684
17. M. Gonzalez-Gaitan Signal dispersal and transduction through the endocytic pathway Nat. Rev. Mol. Cell Biol. 4 2003 213-224
18. M. Gonzalez-Gaitan and H. Stenmark Endocytosis and signaling: A relationship under development Cell 115 2003 513-521
19. J. Gruenberg and H. Stenmark The biogenesis of multivesicular endosomes Nat. Rev. Mol. Cell Biol. 5 2004 317-323
20. N. Gupta-Rossi E. Six O. LeBail F. Logeat P. Chastagner A. Olry A. Israel and C. Brou Monoubiquitination and endocytosis direct γ-secretase cleavage of activated Notch receptor J. Cell Biol. 166 2004 73-83
21. D.A. Harrison P.E. McCoon R. Binari M. Gilman and N. Perrimon Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway Genes Dev. 12 1998 3252-3263
22. L. Hicke and R. Dunn Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins Annu. Rev. Cell Dev. Biol. 19 2003 141-172
23. A. Hierro J. Sun A.S. Rusnak J. Kim G. Prag S.D. Emr and J.H. Hurley Structure of the ESCRT-II endosomal trafficking complex Nature 431 2004 221-225
24. Y. Hong L. Ackerman L.Y. Jan and Y.N. Jan Distinct roles of Bazooka and Stardust in the specification of Drosophila photoreceptor membrane architecture Proc. Natl. Acad. Sci. USA 100 2003 12712-12717
25. K. Hori M. Fostier M. Ito T.J. Fuwa M.J. Go H. Okano M. Baron and K. Matsuno Drosophila deltex mediates suppressor of Hairless-independent and late-endosomal activation of Notch signaling Development 131 2004 5527-5537
26. X.S. Hou M.B. Melnick and N. Perrimon Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs Cell 84 1996 411-419
27. J.P. Incardona J. Gruenberg and H. Roelink Sonic hedgehog induces the segregation of patched and smoothened in endosomes Curr. Biol. 12 2002 983-995
28. G. Jekely and P. Rorth Hrs mediates downregulation of multiple signalling receptors in Drosophila EMBO Rep. 4 2003 1163-1168
29. J. Jia W. Zhang B. Wang R. Trinko and J. Jiang The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis Genes Dev. 17 2003 2514-2519
30. R. Kanwar and M.E. Fortini Notch signaling: A different sort makes the cut Curr. Biol. 14 2004 R1043-R1045
31. D.J. Katzmann M. Babst and S.D. Emr Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I Cell 106 2001 145-155
32. D.J. Katzmann G. Odorizzi and S.D. Emr Receptor downregulation and multivesicular-body sorting Nat. Rev. Mol. Cell Biol. 3 2002 893-905
33. D.J. Katzmann C.J. Stefan M. Babst and S.D. Emr Vps27 recruits ESCRT machinery to endosomes during MVB sorting J. Cell Biol. 162 2003 413-423
34. B.E. Kimmel U. Heberlein and G.M. Rubin The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype Genes Dev. 4 1990 712-727
35. R. Le Borgne and F. Schweisguth Unequal segregation of Neuralized biases Notch activation during asymmetric cell division Dev. Cell 5 2003 139-148
36. C. Le Roy and J.L. Wrana Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling Nat. Rev. Mol. Cell Biol. 6 2005 112-126
37. T. Lee and L. Luo Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development Trends Neurosci. 24 2001 251-254
38. L. Li and S.N. Cohen Tsg101: A novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells Cell 85 1996 319-329
39. T.E. Lloyd R. Atkinson M.N. Wu Y. Zhou G. Pennetta and H.J. Bellen Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila Cell 108 2002 261-269
40. I. Maillard T. Fang and W.S. Pear Regulation of lymphoid development, differentiation, and function by the notch pathway Annu. Rev. Immunol. 23 2005 945-974
41. M. Miaczynska L. Pelkmans and M. Zerial Not just a sink: Endosomes in control of signal transduction Curr. Opin. Cell Biol. 16 2004 400-406
42. D.T. Nellesen E.C. Lai and J.W. Posakony Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators Dev. Biol. 213 1999 33-53
43. T.P. Newsome B. Asling and B.J. Dickson Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics Development 127 2000 851-860
44. S.H. Pasternak J.W. Callahan and D.J. Mahuran The role of the endosomal/ lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: Reexamining the spatial paradox from a lysosomal perspective J. Alzheimers Dis. 6 2004 53-65
45. R.C. Piper A.A. Cooper H. Yang and T.H. Stevens VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae J. Cell Biol. 131 1995 603-617
46. S. Polo S. Pece and P.P. Di Fiore Endocytosis and cancer Curr. Opin. Cell Biol. 16 2004 156-161
47. A. Presente S. Shaw J.S. Nye and A.J. Andres Transgene-mediated RNA interference defines a novel role for notch in chemosensory startle behavior Genesis 34 2002 165-169
48. C.K. Raymond I. Howald-Stevenson C.A. Vater and T.H. Stevens Morphological classification of the yeast vacuolar protein sorting mutants: Evidence for a prevacuolar compartment in class E vps mutants Mol. Biol. Cell 3 1992 1389-1402
49. J. Ruland C. Sirard A. Elia D. MacPherson A. Wakeham L. Li J.L. de la Pompa S.N. Cohen and T.W. Mak p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101 Proc. Natl. Acad. Sci. USA 98 2001 1859-1864
50. T. Sakata H. Sakaguchi L. Tsuda A. Higashitani T. Aigaki K. Matsuno and S. Hayashi Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation Curr. Biol. 14 2004 2228-2236
51. F. Schweisguth Notch signaling activity Curr. Biol. 14 2004 R129-R138
52. E.S. Seto H.J. Bellen and T.E. Lloyd When cell biology meets development: Endocytic regulation of signaling pathways Genes Dev. 16 2002 1314-1336
53. A. Sorkin and M. Von Zastrow Signal transduction and endocytosis: Close encounters of many kinds Nat. Rev. Mol. Cell Biol. 3 2002 600-614
54. A. Sparmann and D. Bar-Sagi Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis Cancer Cell 6 2004 447-458
55. A.A. Sullivan and C.S. Thummel Temporal profiles of nuclear receptor gene expression reveal coordinate transcriptional responses during Drosophila development Mol. Endocrinol. 17 2003 2125-2137
56. Y.H. Sun C.J. Tsai M.M. Green J.L. Chao C.T. Yu T.J. Jaw J.Y. Yeh and V.N. Bolshakov White as a reporter gene to detect transcriptional silencers specifying position-specific gene expression during Drosophila melanogaster eye development Genetics 141 1995 1075-1086
57. G. Tanentzapf C. Smith J. McGlade and U. Tepass Apical, lateral, and basal polarization cues contribute to the development of the follicular epithelium during Drosophila oogenesis J. Cell Biol. 151 2000 891-904
58. N. Tapon N. Ito B.J. Dickson J.E. Treisman and I.K. Hariharan The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation Cell 105 2001 345-355
59. N. Tapon K.F. Harvey D.W. Bell D.C. Wahrer T.A. Schiripo D.A. Haber and I.K. Hariharan salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines Cell 110 2002 467-478
60. H. Teo O. Perisic B. Gonzalez and R.L. Williams ESCRT-II, an endosome-associated complex required for protein sorting: Crystal structure and interactions with ESCRT-III and membranes Dev. Cell 7 2004 559-569
61. U. Tepass C. Theres and E. Knust crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia Cell 61 1990 787-799
62. U. Tepass G. Tanentzapf R. Ward and R. Fehon Epithelial cell polarity and cell junctions in Drosophila Annu. Rev. Genet. 35 2001 747-784
63. Y.C. Tsai and Y.H. Sun Long-range effect of upd, a ligand for Jak/STAT pathway, on cell cycle in Drosophila eye development Genesis 39 2004 141-153
64. R.S. Udan M. Kango-Singh R. Nolo C. Tao and G. Halder Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway Nat. Cell Biol. 5 2003 914-920
65. K.U. Wagner A. Krempler Y. Qi K. Park M.D. Henry A.A. Triplett G. Riedlinger I.E. Rucker and L. Hennighausen Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues Mol. Cell. Biol. 23 2003 150-162
66. U. Weber C. Eroglu and M. Mlodzik Phospholipid membrane composition affects EGF receptor and Notch signaling through effects on endocytosis during Drosophila development Dev. Cell 5 2003 559-570
67. S. Weijzen P. Rizzo M. Braid R. Vaishnav S.M. Jonkheer A. Zlobin B.A. Osborne S. Gottipati J.C. Aster W.C. Hahn et al. Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells Nat. Med. 8 2002 979-986
68. M.B. Wilkin A.M. Carbery M. Fostier H. Aslam S.L. Mazaleyrat J. Higgs A. Myat D.A. Evans M. Cornell and M. Baron Regulation of notch endosomal sorting and signaling by Drosophila Nedd4 family proteins Curr. Biol. 14 2004 2237-2244
69. S. Wu J. Huang J. Dong and D. Pan hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts Cell 114 2003 445-456
70. T. Xu W. Wang S. Zhang R.A. Stewart and W. Yu Identifying tumor suppressors in genetic mosaics: The Drosophila lats gene encodes a putative protein kinase Development 121 1995 1053-1063
71. J. Zeitler C.P. Hsu H. Dionne and D. Bilder Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble J. Cell Biol. 167 2004 1137-1146
72. P.A. Zweidler-McKay and W.S. Pear Notch and T cell malignancy Semin. Cancer Biol. 14 2004 329-340