Attenuation of Notch signalling by the Down-syndrome-associated kinase DYRK1A

Journal of Cell Science

Volumn 122, Issue 10, 2009, Pages 1574-1583

  Fernandez Martinez, Javier ^a,b   Vela, Eva M ^a   Tora Ponsioen, Mireille ^a   Ocaña, Oscar H ^a   Nieto, M Angela ^a   Galceran, Juan ^a  

^a CSIC   (Spain)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Development; Down syndrome; DYRK1A; Notch; Phosphorylation

Indexed keywords

ANKYRIN; JAGGED1; NOTCH RECEPTOR; PROTEIN SERINE THREONINE KINASE; CLK DUAL SPECIFICITY KINASES; CLK DUAL-SPECIFICITY KINASES; DYRK KINASE; NOTCH1 PROTEIN, MOUSE; NOTCH1 RECEPTOR; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CELL CULTURE; CELL DIFFERENTIATION; CELL FATE; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE MODEL; DOWN SYNDROME; EMBRYO; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ACTIVE TRANSPORT; ANIMAL; CELL LINE; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MUTATION; NEOCORTEX; PHOSPHORYLATION; PRENATAL DEVELOPMENT; PROTEIN TERTIARY STRUCTURE; RAT;

ANIMALIA;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL LINE; CELL NUCLEUS; DOWN SYNDROME; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICE; MUTATION; NEOCORTEX; NEURONS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RATS; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 67649969527     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.044354     Document Type: Article

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