메뉴 건너뛰기




Volumn 12, Issue 3, 2010, Pages 278-285

Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex

Author keywords

[No Author keywords available]

Indexed keywords

NEMO LIKE KINASE; NOTCH RECEPTOR; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

EID: 77649273214     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb2028     Document Type: Article
Times cited : (97)

References (33)
  • 1
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas, S., Rand, M. D. & Lake, R. J. Notch signaling: cell fate control and signal integration in development. Science 284, 770-776 (1999).
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 2
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: A simple pathway becomes complex
    • Bray, S. J. Notch signalling: a simple pathway becomes complex. Nature Rev. Mol. Cell Biol. 7, 678-689 (2006).
    • (2006) Nature Rev. Mol. Cell Biol. , vol.7 , pp. 678-689
    • Bray, S.J.1
  • 3
    • 0033662392 scopus 로고    scopus 로고
    • MAML1, a human homologue of Drosophila mastermind, is a transcrip-tional co-activator for NOTCH receptors
    • Wu, L. et al. MAML1, a human homologue of Drosophila mastermind, is a transcrip-tional co-activator for NOTCH receptors. Nature Genet. 26, 484-489 (2000).
    • (2000) Nature Genet. , vol.26 , pp. 484-489
    • Wu, L.1
  • 4
    • 0034978088 scopus 로고    scopus 로고
    • A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters
    • Kitagawa, M. et al. A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters. Mol. Cell. Biol. 21, 4337-4346 (2001).
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4337-4346
    • Kitagawa, M.1
  • 5
    • 34547447032 scopus 로고    scopus 로고
    • Mastermind-1 is required for Notch signal-dependent steps in lymphocyte development in vivo
    • Oyama, T. et al. Mastermind-1 is required for Notch signal-dependent steps in lymphocyte development in vivo. Proc. Natl Acad. Sci. USA 104, 9764-9769 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 9764-9769
    • Oyama, T.1
  • 6
    • 0028364608 scopus 로고
    • Rotation of photoreceptor clusters in the developing Drosophila eye requires the nemo gene
    • Choi, K. W. & Benzer, S. Rotation of photoreceptor clusters in the developing Drosophila eye requires the nemo gene. Cell 78, 125-136 (1994).
    • (1994) Cell , vol.78 , pp. 125-136
    • Choi, K.W.1    Benzer, S.2
  • 7
    • 0033600227 scopus 로고    scopus 로고
    • MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans
    • Meneghini, M. D. et al. MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans. Nature 399, 793-797 (1999).
    • (1999) Nature , vol.399 , pp. 793-797
    • Meneghini, M.D.1
  • 8
    • 3242884717 scopus 로고    scopus 로고
    • T. nemo-like kinase is an essential co-activator of Wnt signaling during early zebrafish development
    • Thorpe, C. J. & Moon, R. T. nemo-like kinase is an essential co-activator of Wnt signaling during early zebrafish development. Development 131, 2899-2909 (2004).
    • (2004) Development , vol.131 , pp. 2899-2909
    • Thorpe, C.J.1    Moon, R.2
  • 9
    • 0035663541 scopus 로고    scopus 로고
    • Abnormal bone marrow stroma in mice deficient for nemo-like kinase, Nlk
    • Kortenjann, M. et al. Abnormal bone marrow stroma in mice deficient for nemo-like kinase, Nlk. Eur. J. Immunol. 31, 3580-3587 (2001).
    • (2001) Eur. J. Immunol. , vol.31 , pp. 3580-3587
    • Kortenjann, M.1
  • 10
    • 0033600239 scopus 로고    scopus 로고
    • The TAK1-NLK-MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF
    • Ishitani, T. et al. The TAK1-NLK-MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF. Nature 399, 798-802 (1999).
    • (1999) Nature , vol.399 , pp. 798-802
    • Ishitani, T.1
  • 11
    • 0037313260 scopus 로고    scopus 로고
    • Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/β-catenin signaling
    • Ishitani, T., Ninomiya-Tsuji, J. & Matsumoto, K. Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/β-catenin signaling. Mol. Cell. Biol. 23, 1379-1389 (2003).
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 1379-1389
    • Ishitani, T.1    Ninomiya-Tsuji, J.2    Matsumoto, K.3
  • 12
    • 11144355861 scopus 로고    scopus 로고
    • Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1 HIPK2 and NLK
    • Kanei-Ishii, C. et al. Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK. Genes Dev. 18, 816-829 (2004).
    • (2004) Genes Dev. , vol.18 , pp. 816-829
    • Kanei-Ishii, C.1
  • 13
    • 20144376594 scopus 로고    scopus 로고
    • STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFβ-activated kinase 1 for STAT3 Ser-727 phosphorylation
    • Kojima, H. et al. STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFβ-activated kinase 1 for STAT3 Ser-727 phosphorylation. Proc. Natl Acad. Sci. USA 102, 4524-4529 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 4524-4529
    • Kojima, H.1
  • 14
    • 1542313926 scopus 로고    scopus 로고
    • Role of the TAK1-NLK-STAT3 pathway in TGF-β-mediated meso-derm induction
    • Ohkawara, B. et al. Role of the TAK1-NLK-STAT3 pathway in TGF-β-mediated meso-derm induction. Genes Dev. 18, 381-386 (2004).
    • (2004) Genes Dev. , vol.18 , pp. 381-386
    • Ohkawara, B.1
  • 15
    • 0029985177 scopus 로고    scopus 로고
    • Analysis of dominant enhancers and suppressors of activated Notch in Drosophila
    • Verheyen, E. M., Purcell, K. J., Fortini, M. E. & Artavanis-Tsakonas, S. Analysis of dominant enhancers and suppressors of activated Notch in Drosophila. Genetics 144, 1127-1141 (1996).
    • (1996) Genetics , vol.144 , pp. 1127-1141
    • Verheyen, E.M.1    Purcell, K.J.2    Fortini, M.E.3    Artavanis-Tsakonas, S.4
  • 16
    • 37249045396 scopus 로고    scopus 로고
    • Investigating the genetic circuitry of mastermind in Drosophila, a notch signal effector
    • Kankel, M. W. et al. Investigating the genetic circuitry of mastermind in Drosophila, a notch signal effector. Genetics 177, 2493-2505 (2007).
    • (2007) Genetics , vol.177 , pp. 2493-2505
    • Kankel, M.W.1
  • 17
    • 0034073379 scopus 로고    scopus 로고
    • SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC to facilitate NotchIC function
    • Zhou, S. et al. SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC to facilitate NotchIC function. Mol. Cell. Biol. 20, 2400-2410 (2000).
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2400-2410
    • Zhou, S.1
  • 18
    • 0033045352 scopus 로고    scopus 로고
    • Her4, a zebrafish homologue of the Drosophila neurogenic gene E(spl), is a target of NOTCH signalling
    • Takke, C., Dornseifer, P., v. Weizsacker, E. & Campos-Ortega, J. A. her4, a zebrafish homologue of the Drosophila neurogenic gene E(spl), is a target of NOTCH signalling. Development 126, 1811-1821 (1999).
    • (1999) Development , vol.126 , pp. 1811-1821
    • Takke, C.1    Dornseifer, P.V.2    Weizsacker, E.3    Campos-Ortega, J.A.4
  • 19
    • 33846096775 scopus 로고    scopus 로고
    • Fluorescent protein expression driven by her4 regulatory elements reveals the spatiotemporal pattern of Notch signaling in the nervous system of zebrafish embryos
    • Yeo, S., Kim, M. J., Kim, H., Huh, T. & Chitnis, A. B. Fluorescent protein expression driven by her4 regulatory elements reveals the spatiotemporal pattern of Notch signaling in the nervous system of zebrafish embryos. Dev. Biol. 301, 555-567 (2007).
    • (2007) Dev. Biol. , vol.301 , pp. 555-567
    • Yeo, S.1    Kim, M.J.2    Kim, H.3    Huh, T.4    Chitnis, A.B.5
  • 20
    • 0036100224 scopus 로고    scopus 로고
    • Involvement of NLK and Sox11 in neural induction in Xenopus development
    • Hyodo-Miura, J. et al. Involvement of NLK and Sox11 in neural induction in Xenopus development. Genes Cells 7, 487-496 (2002).
    • (2002) Genes Cells , vol.7 , pp. 487-496
    • Hyodo-Miura, J.1
  • 21
    • 0031899677 scopus 로고    scopus 로고
    • Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines
    • Bigas, A., Martin, D. I. & Milner, L. A. Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines. Mol. Cell Biol. 18, 2324-2333 (1998).
    • (1998) Mol. Cell Biol. , vol.18 , pp. 2324-2333
    • Bigas, A.1    Martin, D.I.2    Milner, L.A.3
  • 22
    • 0035977049 scopus 로고    scopus 로고
    • Phosphorylation of Ser2078 modulates the Notch2 function in 32D cell differentiation
    • Inglés-Esteve, J., Espinosa, L., Milner, L. A., Caelles, C. & Bigas, A. Phosphorylation of Ser2078 modulates the Notch2 function in 32D cell differentiation. J. Biol. Chem. 276, 44873-44880 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 44873-44880
    • Inglés-Esteve, J.1    Espinosa, L.2    Milner, L.A.3    Caelles, C.4    Bigas, A.5
  • 23
    • 0032403190 scopus 로고    scopus 로고
    • Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region
    • Kurooka, H., Kuroda, K. & Honjo, T. Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region. Nucleic Acids Res. 26, 5448-5455 (1998).
    • (1998) Nucleic Acids Res. , vol.26 , pp. 5448-5455
    • Kurooka, H.1    Kuroda, K.2    Honjo, T.3
  • 24
    • 0034595665 scopus 로고    scopus 로고
    • Functional interaction between the mouse notch1 intracel-lular region and histone acetyltransferases PCAF and GCN5
    • Kurooka, H. & Honjo, T. Functional interaction between the mouse notch1 intracel-lular region and histone acetyltransferases PCAF and GCN5. J. Biol. Chem. 275, 17211-17220 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 17211-17220
    • Kurooka, H.1    Honjo, T.2
  • 25
    • 21744436606 scopus 로고    scopus 로고
    • Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region
    • Pufall, M. A. et al. Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region. Science 309, 142-145 (2005).
    • (2005) Science , vol.309 , pp. 142-145
    • Pufall, M.A.1
  • 26
    • 36049033946 scopus 로고    scopus 로고
    • Hedgehog regulates smoothened activity by inducing a conformational switch
    • Zhao, Y., Tong, C. & Jiang, J. Hedgehog regulates smoothened activity by inducing a conformational switch. Nature 450, 252-258 (2007).
    • (2007) Nature , vol.450 , pp. 252-258
    • Zhao, Y.1    Tong, C.2    Jiang, J.3
  • 27
    • 0030962034 scopus 로고    scopus 로고
    • RPB-L, a transcription factor related to RBP-Jκ
    • Minoguchi, S. et al. RPB-L, a transcription factor related to RBP-Jκ. Mol. Cell. Biol. 17, 2679-2687 (1997).
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2679-2687
    • Minoguchi, S.1
  • 28
    • 0037598796 scopus 로고    scopus 로고
    • Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos
    • Raya, A. et al. Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos. Genes Dev. 17, 1213-1218 (2003).
    • (2003) Genes Dev. , vol.17 , pp. 1213-1218
    • Raya, A.1
  • 29
    • 0030604013 scopus 로고    scopus 로고
    • Zebrafish elav/HuC homologue as a very early neuronal marker
    • Kim, C. H. et al. Zebrafish elav/HuC homologue as a very early neuronal marker. Neurosci. Lett. 216, 109-112 (1996).
    • (1996) Neurosci. Lett. , vol.216 , pp. 109-112
    • Kim, C.H.1
  • 30
    • 0035979241 scopus 로고    scopus 로고
    • Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members
    • Mizutani, T. et al. Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members. Proc. Natl Acad. Sci. USA 98, 9026-9031 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 9026-9031
    • Mizutani, T.1
  • 31
    • 0036296480 scopus 로고    scopus 로고
    • Functional diversity among Notch1, Notch2, and Notch3 receptors
    • Shimizu, K. et al. Functional diversity among Notch1, Notch2, and Notch3 receptors. Biochem. Biophys. Res. Commun. 291, 775-779 (2002).
    • (2002) Biochem. Biophys. Res. Commun. , vol.291 , pp. 775-779
    • Shimizu, K.1
  • 32
    • 0037184924 scopus 로고    scopus 로고
    • Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling
    • Lin, S. E. et al. Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling. J. Biol. Chem. 277, 50612-50620 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 50612-50620
    • Lin, S.E.1
  • 33
    • 0031043087 scopus 로고    scopus 로고
    • The Xenopus homolog of Drosphila Suppressor of Hairless mediates Notch signaling during primary neurogenesis
    • Wettstein, D. A., Turner, D. L. & Kintner, C. The Xenopus homolog of Drosphila Suppressor of Hairless mediates Notch signaling during primary neurogenesis. Development 124, 693-702 (1997).
    • (1997) Development , vol.124 , pp. 693-702
    • Wettstein, D.A.1    Turner, D.L.2    Kintner, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.