메뉴 건너뛰기




Volumn 37, Issue , 2015, Pages 28-34

Emerging roles for the FBXW7 ubiquitin ligase in leukemia and beyond

Author keywords

[No Author keywords available]

Indexed keywords

FBXW7 UBIQUITIN LIGASE; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; F BOX PROTEIN; FBXW7 PROTEIN, HUMAN; UBIQUITIN;

EID: 84942617442     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2015.09.003     Document Type: Review
Times cited : (23)

References (47)
  • 1
    • 84908011711 scopus 로고    scopus 로고
    • Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities
    • Davis R.J., Welcker M., Clurman B.E. Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities. Cancer Cell 2014, 26:455-464.
    • (2014) Cancer Cell , vol.26 , pp. 455-464
    • Davis, R.J.1    Welcker, M.2    Clurman, B.E.3
  • 5
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 6
    • 74049138336 scopus 로고    scopus 로고
    • A reprogrammable mouse strain from gene-targeted embryonic stem cells
    • Stadtfeld M., Maherali N., Borkent M., Hochedlinger K. A reprogrammable mouse strain from gene-targeted embryonic stem cells. Nat Methods 2010, 7:53-55.
    • (2010) Nat Methods , vol.7 , pp. 53-55
    • Stadtfeld, M.1    Maherali, N.2    Borkent, M.3    Hochedlinger, K.4
  • 7
    • 84865563344 scopus 로고    scopus 로고
    • Increased efficiency in the generation of induced pluripotent stem cells by Fbxw7 ablation
    • Okita Y., Matsumoto A., Yumimoto K., Isoshita R., Nakayama K.I. Increased efficiency in the generation of induced pluripotent stem cells by Fbxw7 ablation. Genes Cells 2012, 17:768-777.
    • (2012) Genes Cells , vol.17 , pp. 768-777
    • Okita, Y.1    Matsumoto, A.2    Yumimoto, K.3    Isoshita, R.4    Nakayama, K.I.5
  • 8
    • 42149132696 scopus 로고    scopus 로고
    • Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL
    • Matsuoka S., Oike Y., Onoyama I., Iwama A., Arai F., Takubo K., Mashimo Y., Oguro H., Nitta E., Ito K., et al. Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL. Genes Dev 2008, 22:986-991.
    • (2008) Genes Dev , vol.22 , pp. 986-991
    • Matsuoka, S.1    Oike, Y.2    Onoyama, I.3    Iwama, A.4    Arai, F.5    Takubo, K.6    Mashimo, Y.7    Oguro, H.8    Nitta, E.9    Ito, K.10
  • 10
    • 79952176472 scopus 로고    scopus 로고
    • Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7α overexpression
    • Iriuchishima H., Takubo K., Matsuoka S., Onoyama I., Nakayama K.I., Nojima Y., Suda T. Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7α overexpression. Blood 2011, 117:2373-2377.
    • (2011) Blood , vol.117 , pp. 2373-2377
    • Iriuchishima, H.1    Takubo, K.2    Matsuoka, S.3    Onoyama, I.4    Nakayama, K.I.5    Nojima, Y.6    Suda, T.7
  • 11
    • 84907972984 scopus 로고    scopus 로고
    • Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation
    • Siu K.T., Xu Y., Swartz K.L., Bhattacharyya M., Gurbuxani S., Hua Y., Minella A.C. Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation. Mol Cell Biol 2014, 34:3244-3258.
    • (2014) Mol Cell Biol , vol.34 , pp. 3244-3258
    • Siu, K.T.1    Xu, Y.2    Swartz, K.L.3    Bhattacharyya, M.4    Gurbuxani, S.5    Hua, Y.6    Minella, A.C.7
  • 12
    • 84880548336 scopus 로고    scopus 로고
    • The intestinal crypt, a prototype stem cell compartment
    • Clevers H. The intestinal crypt, a prototype stem cell compartment. Cell 2013, 154:274-284.
    • (2013) Cell , vol.154 , pp. 274-284
    • Clevers, H.1
  • 13
    • 79959187704 scopus 로고    scopus 로고
    • Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors
    • van Es J.H., de Geest N., van de Born M., Clevers H., Hassan B.A. Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors. Nat Commun 2010, 1:18.
    • (2010) Nat Commun , vol.1 , pp. 18
    • van Es, J.H.1    de Geest, N.2    van de Born, M.3    Clevers, H.4    Hassan, B.A.5
  • 14
    • 84879384549 scopus 로고    scopus 로고
    • Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions
    • Sancho R., Blake S.M., Tendeng C., Clurman B.E., Lewis J., Behrens A. Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions. PLoS Biol 2013, 11:e1001586.
    • (2013) PLoS Biol , vol.11 , pp. e1001586
    • Sancho, R.1    Blake, S.M.2    Tendeng, C.3    Clurman, B.E.4    Lewis, J.5    Behrens, A.6
  • 15
    • 77956165036 scopus 로고    scopus 로고
    • F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor
    • Sancho R., Jandke A., Davis H., Diefenbacher M.E., Tomlinson I., Behrens A. F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor. Gastroenterology 2010, 139:929-941.
    • (2010) Gastroenterology , vol.139 , pp. 929-941
    • Sancho, R.1    Jandke, A.2    Davis, H.3    Diefenbacher, M.E.4    Tomlinson, I.5    Behrens, A.6
  • 19
    • 84872498439 scopus 로고    scopus 로고
    • Signaling mechanisms regulating adult neural stem cells and neurogenesis
    • Faigle R., Song H. Signaling mechanisms regulating adult neural stem cells and neurogenesis. Biochim Biophys Acta 2013, 1830:2435-2448.
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 2435-2448
    • Faigle, R.1    Song, H.2
  • 21
    • 79953899846 scopus 로고    scopus 로고
    • Fbxw7-dependent degradation of Notch is required for control of "stemness" and neuronal-glial differentiation in neural stem cells
    • Matsumoto A., Onoyama I., Sunabori T., Kageyama R., Okano H., Nakayama K.I. Fbxw7-dependent degradation of Notch is required for control of "stemness" and neuronal-glial differentiation in neural stem cells. J Biol Chem 2011, 286:13754-13764.
    • (2011) J Biol Chem , vol.286 , pp. 13754-13764
    • Matsumoto, A.1    Onoyama, I.2    Sunabori, T.3    Kageyama, R.4    Okano, H.5    Nakayama, K.I.6
  • 23
    • 1342275412 scopus 로고    scopus 로고
    • The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling
    • Nateri A.S., Riera-Sans L., Da Costa C., Behrens A. The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling. Science 2004, 303:1374-1378.
    • (2004) Science , vol.303 , pp. 1374-1378
    • Nateri, A.S.1    Riera-Sans, L.2    Da Costa, C.3    Behrens, A.4
  • 24
    • 2342510386 scopus 로고    scopus 로고
    • Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
    • Dor Y., Brown J., Martinez O.I., Melton D.A. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 2004, 429:41-46.
    • (2004) Nature , vol.429 , pp. 41-46
    • Dor, Y.1    Brown, J.2    Martinez, O.I.3    Melton, D.A.4
  • 25
    • 84905815332 scopus 로고    scopus 로고
    • Loss of Fbw7 reprograms adult pancreatic ductal cells into alpha, delta, and beta cells
    • Sancho R., Gruber R., Gu G., Behrens A. Loss of Fbw7 reprograms adult pancreatic ductal cells into alpha, delta, and beta cells. Cell Stem Cell 2014, 15:139-153.
    • (2014) Cell Stem Cell , vol.15 , pp. 139-153
    • Sancho, R.1    Gruber, R.2    Gu, G.3    Behrens, A.4
  • 27
    • 34047249627 scopus 로고    scopus 로고
    • Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases
    • Hao B., Oehlmann S., Sowa M.E., Harper J.W., Pavletich N.P. Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases. Mol Cell 2007, 26:131-143.
    • (2007) Mol Cell , vol.26 , pp. 131-143
    • Hao, B.1    Oehlmann, S.2    Sowa, M.E.3    Harper, J.W.4    Pavletich, N.P.5
  • 28
    • 0037462424 scopus 로고    scopus 로고
    • Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase
    • Orlicky S., Tang X., Willems A., Tyers M., Sicheri F. Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase. Cell 2003, 112:243-256.
    • (2003) Cell , vol.112 , pp. 243-256
    • Orlicky, S.1    Tang, X.2    Willems, A.3    Tyers, M.4    Sicheri, F.5
  • 31
    • 79952370202 scopus 로고    scopus 로고
    • The cancer stem cell: premises, promises and challenges
    • Clevers H. The cancer stem cell: premises, promises and challenges. Nat Med 2011, 17:313-319.
    • (2011) Nat Med , vol.17 , pp. 313-319
    • Clevers, H.1
  • 32
  • 36
    • 84877587618 scopus 로고    scopus 로고
    • FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation
    • Malyukova A., Brown S., Papa R., O'Brien R., Giles J., Trahair T.N., Dalla Pozza L., Sutton R., Liu T., Haber M., et al. FBXW7 regulates glucocorticoid response in T-cell acute lymphoblastic leukaemia by targeting the glucocorticoid receptor for degradation. Leukemia 2013, 27:1053-1062.
    • (2013) Leukemia , vol.27 , pp. 1053-1062
    • Malyukova, A.1    Brown, S.2    Papa, R.3    O'Brien, R.4    Giles, J.5    Trahair, T.N.6    Dalla Pozza, L.7    Sutton, R.8    Liu, T.9    Haber, M.10
  • 39
    • 34548658230 scopus 로고    scopus 로고
    • Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis
    • Dai C., Whitesell L., Rogers A.B., Lindquist S. Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis. Cell 2007, 130:1005-1018.
    • (2007) Cell , vol.130 , pp. 1005-1018
    • Dai, C.1    Whitesell, L.2    Rogers, A.B.3    Lindquist, S.4
  • 42
    • 84879420289 scopus 로고    scopus 로고
    • Prognostic significance of Fbw7 in human melanoma and its role in cell migration
    • Cheng Y., Chen G., Martinka M., Ho V., Li G. Prognostic significance of Fbw7 in human melanoma and its role in cell migration. J Invest Dermatol 2013, 133:1794-1802.
    • (2013) J Invest Dermatol , vol.133 , pp. 1794-1802
    • Cheng, Y.1    Chen, G.2    Martinka, M.3    Ho, V.4    Li, G.5
  • 43
    • 84873051970 scopus 로고    scopus 로고
    • The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with mediator
    • Davis M.A., Larimore E.A., Fissel B.M., Swanger J., Taatjes D.J., Clurman B.E. The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with mediator. Genes Dev 2013, 27:151-156.
    • (2013) Genes Dev , vol.27 , pp. 151-156
    • Davis, M.A.1    Larimore, E.A.2    Fissel, B.M.3    Swanger, J.4    Taatjes, D.J.5    Clurman, B.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.