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Volumn , Issue , 2013, Pages 239-296

The role of cyclooxygenases and lipoxygenases in the regulation of tumor angiogenesis

Author keywords

Angiogenesis; Cancer; Cyclooxygenase; Lipoxygenase; Metastasis; Natural agents; Pharmacological inhibitors; Prostaglandins; Thromboxane synthase

Indexed keywords


EID: 84977740369     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/b14842     Document Type: Chapter
Times cited : (2)

References (302)
  • 1
    • 1642495716 scopus 로고    scopus 로고
    • Prostaglandin E2 induces degranulation-independent production of vascular endothelial growth factor by human mast cells
    • Abdel-Majid, R. M. and J. S. Marshall (2004). “Prostaglandin E2 induces degranulation-independent production of vascular endothelial growth factor by human mast cells.” J Immunol 172(2): 1227-1236.
    • (2004) J Immunol , vol.172 , Issue.2 , pp. 1227-1236
    • Abdel-Majid, R.M.1    Marshall, J.S.2
  • 3
    • 6944250259 scopus 로고    scopus 로고
    • Role of resveratrol in prevention and therapy of cancer: Preclinical and clinical studies
    • Aggarwal, B. B., A. Bhardwaj, R. S. Aggarwal, N. P. Seeram, S. Shishodia and Y. Takada (2004). “Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.” Anticancer Res 24(5A): 2783-2840.
    • (2004) Anticancer Res , vol.24 , Issue.5A , pp. 2783-2840
    • Aggarwal, B.B.1    Bhardwaj, A.2    Aggarwal, R.S.3    Seeram, N.P.4    Shishodia, S.5    Takada, Y.6
  • 4
    • 33747466079 scopus 로고    scopus 로고
    • Prostanoid signal transduction and gene expression in the endothelium: Role in cardiovascular diseases
    • Alfranca, A., M. A. Iniguez, M. Fresno and J. M. Redondo (2006). “Prostanoid signal transduction and gene expression in the endothelium: role in cardiovascular diseases.” Cardiovasc Res 70(3): 446-456.
    • (2006) Cardiovasc Res , vol.70 , Issue.3 , pp. 446-456
    • Alfranca, A.1    Iniguez, M.A.2    Fresno, M.3    Redondo, J.M.4
  • 9
    • 0030960506 scopus 로고    scopus 로고
    • Interferon gamma induces prostaglandin G/H synthase-2 through an autocrine loop via the epidermal growth factor receptor in human bronchial epithelial cells
    • Asano, K., H. Nakamura, C. M. Lilly, M. Klagsbrun and J. M. Drazen (1997). “Interferon gamma induces prostaglandin G/H synthase-2 through an autocrine loop via the epidermal growth factor receptor in human bronchial epithelial cells.” J Clin Invest 99(5): 1057-1063.
    • (1997) J Clin Invest , vol.99 , Issue.5 , pp. 1057-1063
    • Asano, K.1    Nakamura, H.2    Lilly, C.M.3    Klagsbrun, M.4    Drazen, J.M.5
  • 10
    • 1842559912 scopus 로고    scopus 로고
    • 2receptor agonists antagonize the proangiogenic effects of fibroblast growth factor-2: Role of receptor internalization, thrombospondin-1, and alpha(v)beta3
    • 2receptor agonists antagonize the proangiogenic effects of fibroblast growth factor-2: role of receptor internalization, thrombospondin-1, and alpha(v)beta3.” Circ Res 94(6): 735-742.
    • (2004) Circ Res , vol.94 , Issue.6 , pp. 735-742
    • Ashton, A.W.1    Cheng, Y.2    Helisch, A.3    Ware, J.A.4
  • 11
    • 4143069201 scopus 로고    scopus 로고
    • 2 receptor signaling inhibits vascular endothelial growth factor-induced endothelial cell differentiation and migration
    • 2 receptor signaling inhibits vascular endothelial growth factor-induced endothelial cell differentiation and migration.” Circ Res 95(4): 372-379.
    • (2004) Circ Res , vol.95 , Issue.4 , pp. 372-379
    • Ashton, A.W.1    Ware, J.A.2
  • 12
    • 0033544876 scopus 로고    scopus 로고
    • Inhibition of endothelial cell migration, intercellular communication, and vascular tube formation by thromboxane A(2)
    • Ashton, A. W., R. Yokota, G. John, S. Zhao, S. O. Suadicani, D. C. Spray and J. A. Ware (1999). “Inhibition of endothelial cell migration, intercellular communication, and vascular tube formation by thromboxane A(2).” J Biol Chem 274(50): 35562-35570.
    • (1999) J Biol Chem , vol.274 , Issue.50 , pp. 35562-35570
    • Ashton, A.W.1    Yokota, R.2    John, G.3    Zhao, S.4    Suadicani, S.O.5    Spray, D.C.6    Ware, J.A.7
  • 14
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • Bhowmick, N. A., E. G. Neilson and H. L. Moses (2004). “Stromal fibroblasts in cancer initiation and progression.” Nature 432(7015): 332-337.
    • (2004) Nature , vol.432 , Issue.7015 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 15
    • 54349091392 scopus 로고    scopus 로고
    • Curcumin inhibits VEGFmediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition
    • Binion, D. G., M. F. Otterson and P. Rafiee (2008). “Curcumin inhibits VEGFmediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition.” Gut 57(11): 1509-1517.
    • (2008) Gut , vol.57 , Issue.11 , pp. 1509-1517
    • Binion, D.G.1    Otterson, M.F.2    Rafiee, P.3
  • 16
    • 60349120941 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha is crucial for iloprost-induced in vivo angiogenesis and vascular endothelial growth factor upregulation
    • Biscetti, F., E. Gaetani, A. Flex, G. Straface, G. Pecorini, F. Angelini, E. Stigliano, T. Aprahamian, R. C. Smith, J. J. Castellot and R. Pola (2009). “Peroxisome proliferator-activated receptor alpha is crucial for iloprost-induced in vivo angiogenesis and vascular endothelial growth factor upregulation.” J Vasc Res 46(2): 103-108.
    • (2009) J Vasc Res , vol.46 , Issue.2 , pp. 103-108
    • Biscetti, F.1    Gaetani, E.2    Flex, A.3    Straface, G.4    Pecorini, G.5    Angelini, F.6    Stigliano, E.7    Aprahamian, T.8    Smith, R.C.9    Castellot, J.J.10    Pola, R.11
  • 17
    • 0034057069 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in the cardiovascular system
    • Bishop-Bailey, D. (2000). “Peroxisome proliferator-activated receptors in the cardiovascular system.” Br J Pharmacol 129(5): 823-834.
    • (2000) Br J Pharmacol , vol.129 , Issue.5 , pp. 823-834
    • Bishop-Bailey, D.1
  • 18
    • 19544368251 scopus 로고    scopus 로고
    • Arachidonic acid cascade in endothelial pathobiology
    • Bogatcheva, N. V., M. G. Sergeeva, S. M. Dudek and A. D. Verin (2005). “Arachidonic acid cascade in endothelial pathobiology.” Microvasc Res 69(3): 107-127.
    • (2005) Microvasc Res , vol.69 , Issue.3 , pp. 107-127
    • Bogatcheva, N.V.1    Sergeeva, M.G.2    Dudek, S.M.3    Verin, A.D.4
  • 21
    • 0031008470 scopus 로고    scopus 로고
    • Discovery of a second 15S-lipoxygenase in humans
    • Brash, A. R., W. E. Boeglin and M. S. Chang (1997). “Discovery of a second 15S-lipoxygenase in humans.” Proc Natl Acad Sci USA 94(12): 6148-6152.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.12 , pp. 6148-6152
    • Brash, A.R.1    Boeglin, W.E.2    Chang, M.S.3
  • 23
    • 7644231582 scopus 로고    scopus 로고
    • Up-regulation of the enzymes involved in prostacyclin synthesis via Ras induces vascular endothelial growth factor
    • Buchanan, F. G., W. Chang, H. Sheng, J. Shao, J. D. Morrow and R. N. DuBois (2004). “Up-regulation of the enzymes involved in prostacyclin synthesis via Ras induces vascular endothelial growth factor.” Gastroenterology 127(5): 1391-1400.
    • (2004) Gastroenterology , vol.127 , Issue.5 , pp. 1391-1400
    • Buchanan, F.G.1    Chang, W.2    Sheng, H.3    Shao, J.4    Morrow, J.D.5    DuBois, R.N.6
  • 25
    • 0041816104 scopus 로고    scopus 로고
    • Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor
    • Buchanan, F. G., D. Wang, F. Bargiacchi and R. N. DuBois (2003). “Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor.” J Biol Chem 278(37): 35451-35457.
    • (2003) J Biol Chem , vol.278 , Issue.37 , pp. 35451-35457
    • Buchanan, F.G.1    Wang, D.2    Bargiacchi, F.3    DuBois, R.N.4
  • 26
    • 26644471951 scopus 로고    scopus 로고
    • Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
    • Casanovas, O., D. J. Hicklin, G. Bergers and D. Hanahan (2005). “Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors.” Cancer Cell 8(4): 299-309.
    • (2005) Cancer Cell , vol.8 , Issue.4 , pp. 299-309
    • Casanovas, O.1    Hicklin, D.J.2    Bergers, G.3    Hanahan, D.4
  • 27
    • 21644438985 scopus 로고    scopus 로고
    • New aspects on the role of lipoxygenases in cancer progression
    • Catalano, A. and A. Procopio (2005). “New aspects on the role of lipoxygenases in cancer progression.” Histol Histopathol 20(3): 969-975.
    • (2005) Histol Histopathol , vol.20 , Issue.3 , pp. 969-975
    • Catalano, A.1    Procopio, A.2
  • 28
    • 79952328452 scopus 로고    scopus 로고
    • Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer
    • Cathcart, M. C., K. Gately, R. Cummins, E. Kay, O. B. KJ and G. P. Pidgeon (2011). “Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer.” Mol Cancer 10(1): 25.
    • (2011) Mol Cancer , vol.10 , Issue.1 , pp. 25
    • Cathcart, M.C.1    Gately, K.2    Cummins, R.3    Kay, E.4    Kj, O.B.5    Pidgeon, G.P.6
  • 29
    • 83855165094 scopus 로고    scopus 로고
    • Eicosanoid signalling pathways in the development and progression of colorectal cancer: Novel approaches for prevention/intervention
    • Cathcart, M. C., J. Lysaght and G. P. Pidgeon (2011). “Eicosanoid signalling pathways in the development and progression of colorectal cancer: novel approaches for prevention/intervention.” Cancer Metastasis Rev 30(3-4): 363-385.
    • (2011) Cancer Metastasis Rev , vol.30 , Issue.3-4 , pp. 363-385
    • Cathcart, M.C.1    Lysaght, J.2    Pidgeon, G.P.3
  • 31
    • 0041707878 scopus 로고    scopus 로고
    • The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy
    • Celotti, F. and T. Durand (2003). “The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy.” Prostaglandins Other Lipid Mediat 71(3-4): 147-162.
    • (2003) Prostaglandins Other Lipid Mediat , vol.71 , Issue.3-4 , pp. 147-162
    • Celotti, F.1    Durand, T.2
  • 33
    • 0347717578 scopus 로고    scopus 로고
    • Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression
    • Chang, S. H., C. H. Liu, R. Conway, D. K. Han, K. Nithipatikom, O. C. Trifan, T. F. Lane and T. Hla (2004). “Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression.” Proc Natl Acad Sci USA 101(2): 591-596.
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.2 , pp. 591-596
    • Chang, S.H.1    Liu, C.H.2    Conway, R.3    Han, D.K.4    Nithipatikom, K.5    Trifan, O.C.6    Lane, T.F.7    Hla, T.8
  • 34
    • 85054717126 scopus 로고    scopus 로고
    • Overexpression of 5-lipoxygenase and its relation with cell proliferation and angiogenesis in 7,12-dimethylbenz(alpha) anthracene-induced rat mammary carcinogenesis
    • Dec. 28 [Epub ahead of print]
    • Chatterjee, M., S. Das and K. Roy (2011). “Overexpression of 5-lipoxygenase and its relation with cell proliferation and angiogenesis in 7,12-dimethylbenz(alpha) anthracene-induced rat mammary carcinogenesis.” Mol Carcinog Dec. 28 [Epub ahead of print].
    • (2011) Mol Carcinog
    • Chatterjee, M.1    Das, S.2    Roy, K.3
  • 35
    • 5144227630 scopus 로고    scopus 로고
    • Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis
    • Chen, X., S. Wang, N. Wu, S. Sood, P. Wang, Z. Jin, D. G. Beer, T. J. Giordano, Y. Lin, W. C. Shih, R. A. Lubet and C. S. Yang (2004). “Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis.” Clin Cancer Res 10(19): 6703-6709.
    • (2004) Clin Cancer Res , vol.10 , Issue.19 , pp. 6703-6709
    • Chen, X.1    Wang, S.2    Wu, N.3    Sood, S.4    Wang, P.5    Jin, Z.6    Beer, D.G.7    Giordano, T.J.8    Lin, Y.9    Shih, W.C.10    Lubet, R.A.11    Yang, C.S.12
  • 36
    • 0031594643 scopus 로고    scopus 로고
    • Prostaglandin E2 induces vascular endothelial growth factor and basic fibroblast growth factor mRNA expression in cultured rat Muller cells
    • Cheng, T., W. Cao, R. Wen, R. H. Steinberg and M. M. LaVail (1998). “Prostaglandin E2 induces vascular endothelial growth factor and basic fibroblast growth factor mRNA expression in cultured rat Muller cells.” Invest Ophthalmol Vis Sci 39(3): 581-591.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , Issue.3 , pp. 581-591
    • Cheng, T.1    Cao, W.2    Wen, R.3    Steinberg, R.H.4    LaVail, M.M.5
  • 39
    • 0032776939 scopus 로고    scopus 로고
    • The arachidonate 12/15 lipoxygenases. A review of tissue expression and biologic function
    • Conrad, D. J. (1999). “The arachidonate 12/15 lipoxygenases. A review of tissue expression and biologic function.” Clin Rev Allergy Immunol 17(1-2): 71-89.
    • (1999) Clin Rev Allergy Immunol , vol.17 , Issue.1-2 , pp. 71-89
    • Conrad, D.J.1
  • 40
    • 0034523901 scopus 로고    scopus 로고
    • The role of cyclooxygenase and lipoxygenase in cancer chemoprevention
    • Cuendet, M. and J. M. Pezzuto (2000). “The role of cyclooxygenase and lipoxygenase in cancer chemoprevention.” Drug Metabol Drug Interact 17(1-4): 109-157.
    • (2000) Drug Metabol Drug Interact , vol.17 , Issue.1-4 , pp. 109-157
    • Cuendet, M.1    Pezzuto, J.M.2
  • 41
    • 33846688590 scopus 로고    scopus 로고
    • Effects of vascular endothelial growth factor receptor inhibitor SU5416 and prostacyclin on murine lung metastasis
    • Cuneo, K. C., A. Fu, K. L. Osusky and L. Geng (2007). “Effects of vascular endothelial growth factor receptor inhibitor SU5416 and prostacyclin on murine lung metastasis.” Anticancer Drugs 18(3): 349-355.
    • (2007) Anticancer Drugs , vol.18 , Issue.3 , pp. 349-355
    • Cuneo, K.C.1    Fu, A.2    Osusky, K.L.3    Geng, L.4
  • 43
    • 0030018263 scopus 로고    scopus 로고
    • Anti-metastatic prostacyclins inhibit the adhesion of colon carcinoma to endothelial cells by blocking E-selectin expression
    • Daneker, G. W., S. A. Lund, S. W. Caughman, C. A. Staley and W. C. Wood (1996). “Anti-metastatic prostacyclins inhibit the adhesion of colon carcinoma to endothelial cells by blocking E-selectin expression.” Clin Exp Metastasis 14(3): 230-238.
    • (1996) Clin Exp Metastasis , vol.14 , Issue.3 , pp. 230-238
    • Daneker, G.W.1    Lund, S.A.2    Caughman, S.W.3    Staley, C.A.4    Wood, W.C.5
  • 44
    • 0033567459 scopus 로고    scopus 로고
    • 2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis
    • 2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis.” Cancer Res 59(18): 4574-4577.
    • (1999) Cancer Res , vol.59 , Issue.18 , pp. 4574-4577
    • Daniel, T.O.1    Liu, H.2    Morrow, J.D.3    Crews, B.C.4    Marnett, L.J.5
  • 47
    • 0034798718 scopus 로고    scopus 로고
    • Targeting angiogenic processes by combination rofecoxib and ionizing radiation
    • Dicker, A. P., T. L. Williams and D. S. Grant (2001). “Targeting angiogenic processes by combination rofecoxib and ionizing radiation.” Am J Clin Oncol 24(5): 438-442.
    • (2001) Am J Clin Oncol , vol.24 , Issue.5 , pp. 438-442
    • Dicker, A.P.1    Williams, T.L.2    Grant, D.S.3
  • 49
    • 0031808163 scopus 로고    scopus 로고
    • Effect of COX-1 and COX-2 inhibition on induction and maintenance of carrageenan-evoked thermal hyperalgesia in rats
    • Dirig, D. M., P. C. Isakson and T. L. Yaksh (1998). “Effect of COX-1 and COX-2 inhibition on induction and maintenance of carrageenan-evoked thermal hyperalgesia in rats.” J Pharmacol Exp Ther 285(3): 1031-1038.
    • (1998) J Pharmacol Exp Ther , vol.285 , Issue.3 , pp. 1031-1038
    • Dirig, D.M.1    Isakson, P.C.2    Yaksh, T.L.3
  • 51
    • 0037195421 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes integrin alpha Vbeta 3-dependent endothelial cell adhesion, racactivation, and spreading through cAMP/PKA-dependent signaling
    • Dormond, O., M. Bezzi, A. Mariotti and C. Ruegg (2002). “Prostaglandin E2 promotes integrin alpha Vbeta 3-dependent endothelial cell adhesion, racactivation, and spreading through cAMP/PKA-dependent signaling.” J Biol Chem 277(48): 45838-45846.
    • (2002) J Biol Chem , vol.277 , Issue.48 , pp. 45838-45846
    • Dormond, O.1    Bezzi, M.2    Mariotti, A.3    Ruegg, C.4
  • 52
    • 0034791297 scopus 로고    scopus 로고
    • NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis
    • Dormond, O., A. Foletti, C. Paroz and C. Ruegg (2001). “NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis.” Nat Med 7(9): 1041-1047.
    • (2001) Nat Med , vol.7 , Issue.9 , pp. 1041-1047
    • Dormond, O.1    Foletti, A.2    Paroz, C.3    Ruegg, C.4
  • 54
    • 80054910709 scopus 로고    scopus 로고
    • Serum vascular endothelial growth factor and COX-2/5-LOX inhibition in advanced non-small cell lung cancer: Cancer and Leukemia Group B 150304
    • Edelman, M. J., L. Hodgson, X. Wang, R. Christenson, S. Jewell, E. Vokes and R. Kratzke (2011). “Serum vascular endothelial growth factor and COX-2/5-LOX inhibition in advanced non-small cell lung cancer: Cancer and Leukemia Group B 150304.” J Thorac Oncol 6(11): 1902-1906.
    • (2011) J Thorac Oncol , vol.6 , Issue.11 , pp. 1902-1906
    • Edelman, M.J.1    Hodgson, L.2    Wang, X.3    Christenson, R.4    Jewell, S.5    Vokes, E.6    Kratzke, R.7
  • 55
    • 39749149266 scopus 로고    scopus 로고
    • Eicosanoid modulation in advanced lung cancer: Cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy - Cancer and Leukemia Group B Trial 30203
    • Edelman, M. J., D. Watson, X. Wang, C. Morrison, R. A. Kratzke, S. Jewell, L. Hodgson, A. M. Mauer, A. Gajra, G. A. Masters, M. Bedor, E. E. Vokes and M. J. Green (2008). “Eicosanoid modulation in advanced lung cancer: cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy - Cancer and Leukemia Group B Trial 30203.” J Clin Oncol 26(6): 848-855.
    • (2008) J Clin Oncol , vol.26 , Issue.6 , pp. 848-855
    • Edelman, M.J.1    Watson, D.2    Wang, X.3    Morrison, C.4    Kratzke, R.A.5    Jewell, S.6    Hodgson, L.7    Mauer, A.M.8    Gajra, A.9    Masters, G.A.10    Bedor, M.11    Vokes, E.E.12    Green, M.J.13
  • 56
    • 0037652234 scopus 로고    scopus 로고
    • Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors
    • Ermert, L., C. Dierkes and M. Ermert (2003). “Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors.” Clin Cancer Res 9(5): 1604-1610.
    • (2003) Clin Cancer Res , vol.9 , Issue.5 , pp. 1604-1610
    • Ermert, L.1    Dierkes, C.2    Ermert, M.3
  • 57
    • 0036100383 scopus 로고    scopus 로고
    • Transcellular biosynthesis contributes to the production of leukotrienes during inflammatory responses in vivo
    • Fabre, J. E., J. L. Goulet, E. Riche, M. Nguyen, K. Coggins, S. Offenbacher and B. H. Koller (2002). “Transcellular biosynthesis contributes to the production of leukotrienes during inflammatory responses in vivo.” J Clin Invest 109(10): 1373-1380.
    • (2002) J Clin Invest , vol.109 , Issue.10 , pp. 1373-1380
    • Fabre, J.E.1    Goulet, J.L.2    Riche, E.3    Nguyen, M.4    Coggins, K.5    Offenbacher, S.6    Koller, B.H.7
  • 59
    • 70450160977 scopus 로고    scopus 로고
    • Topical chemoprevention of skin cancer in mice, using combined inhibitors of 5-lipoxygenase and cyclo-oxygenase-2
    • Fegn, L. and Z. Wang (2009). “Topical chemoprevention of skin cancer in mice, using combined inhibitors of 5-lipoxygenase and cyclo-oxygenase-2.” J Laryngol Otol 123(8): 880-884.
    • (2009) J Laryngol Otol , vol.123 , Issue.8 , pp. 880-884
    • Fegn, L.1    Wang, Z.2
  • 60
    • 0041323114 scopus 로고    scopus 로고
    • The effect of the selective cyclooxygenase-2 inhibitor rofecoxib on human colorectal cancer liver metastases
    • Fenwick, S. W., G. J. Toogood, J. P. Lodge and M. A. Hull (2003). “The effect of the selective cyclooxygenase-2 inhibitor rofecoxib on human colorectal cancer liver metastases.” Gastroenterology 125(3): 716-729.
    • (2003) Gastroenterology , vol.125 , Issue.3 , pp. 716-729
    • Fenwick, S.W.1    Toogood, G.J.2    Lodge, J.P.3    Hull, M.A.4
  • 61
    • 0028114985 scopus 로고
    • The implications of angiogenesis for the biology and therapy of cancer metastasis
    • Fidler, I. J. and L. M. Ellis (1994). “The implications of angiogenesis for the biology and therapy of cancer metastasis.” Cell 79(2): 185-188.
    • (1994) Cell , vol.79 , Issue.2 , pp. 185-188
    • Fidler, I.J.1    Ellis, L.M.2
  • 62
    • 42249111036 scopus 로고    scopus 로고
    • The potential predictive value of cyclooxygenase-2 expression and increased risk of gastrointestinal hemorrhage in advanced non-small cell lung cancer patients treated with erlotinib and celecoxib
    • Fidler, M. J., A. Argiris, J. D. Patel, D. H. Johnson, A. Sandler, V. M. Villaflor, J. T. Coon, L. Buckingham, K. Kaiser, S. Basu and P. Bonomi (2008). “The potential predictive value of cyclooxygenase-2 expression and increased risk of gastrointestinal hemorrhage in advanced non-small cell lung cancer patients treated with erlotinib and celecoxib.” Clin Cancer Res 14(7): 2088-2094.
    • (2008) Clin Cancer Res , vol.14 , Issue.7 , pp. 2088-2094
    • Fidler, M.J.1    Argiris, A.2    Patel, J.D.3    Johnson, D.H.4    Sandler, A.5    Villaflor, V.M.6    Coon, J.T.7    Buckingham, L.8    Kaiser, K.9    Basu, S.10    Bonomi, P.11
  • 63
    • 70349682610 scopus 로고    scopus 로고
    • Prostaglandin E(2) primes the angiogenic switch via a synergic interaction with the fibroblast growth factor-2 pathway
    • Finetti, F., S. Donnini, A. Giachetti, L. Morbidelli and M. Ziche (2009). “Prostaglandin E(2) primes the angiogenic switch via a synergic interaction with the fibroblast growth factor-2 pathway.” Circ Res 105(7): 657-666.
    • (2009) Circ Res , vol.105 , Issue.7 , pp. 657-666
    • Finetti, F.1    Donnini, S.2    Giachetti, A.3    Morbidelli, L.4    Ziche, M.5
  • 64
    • 38349183605 scopus 로고    scopus 로고
    • Prostaglandin E2 regulates angiogenesis via activation of fibroblast growth factor receptor-1
    • Finetti, F., R. Solito, L. Morbidelli, A. Giachetti, M. Ziche and S. Donnini (2008). “Prostaglandin E2 regulates angiogenesis via activation of fibroblast growth factor receptor-1.” J Biol Chem 283(4): 2139-2146.
    • (2008) J Biol Chem , vol.283 , Issue.4 , pp. 2139-2146
    • Finetti, F.1    Solito, R.2    Morbidelli, L.3    Giachetti, A.4    Ziche, M.5    Donnini, S.6
  • 65
    • 0042388365 scopus 로고    scopus 로고
    • Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin
    • Fiorucci, S., E. Distrutti, A. Mencarelli, A. Morelli, S. A. Laufor, G. Cirino and J. L. Wallace (2003). “Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin.” Br J Pharmacol 139(7): 1351-1359.
    • (2003) Br J Pharmacol , vol.139 , Issue.7 , pp. 1351-1359
    • Fiorucci, S.1    Distrutti, E.2    Mencarelli, A.3    Morelli, A.4    Laufor, S.A.5    Cirino, G.6    Wallace, J.L.7
  • 66
    • 33749240167 scopus 로고    scopus 로고
    • Inhibition of gastric cancer cells associated angiogenesis by 15d-prostaglandin J2 through the downregulation of angiopoietin-1
    • Fu, Y. G., J. J. Sung, K. C. Wu, A. H. Bai, M. C. Chan, J. Yu, D. M. Fan and W. K. Leung (2006). “Inhibition of gastric cancer cells associated angiogenesis by 15d-prostaglandin J2 through the downregulation of angiopoietin-1.” Cancer Lett 243(2): 246-254.
    • (2006) Cancer Lett , vol.243 , Issue.2 , pp. 246-254
    • Fu, Y.G.1    Sung, J.J.2    Wu, K.C.3    Bai, A.H.4    Chan, M.C.5    Yu, J.6    Fan, D.M.7    Leung, W.K.8
  • 67
    • 78650690612 scopus 로고    scopus 로고
    • Prostaglandin E regulates cellular migration via induction of vascular endothelial growth factor receptor-1 in HCA-7 human colon cancer cells
    • Fujino, H., K. Toyomura, X. B. Chen, J. W. Regan and T. Murayama (2011). “Prostaglandin E regulates cellular migration via induction of vascular endothelial growth factor receptor-1 in HCA-7 human colon cancer cells.” Biochem Pharmacol 81(3): 379-387.
    • (2011) Biochem Pharmacol , vol.81 , Issue.3 , pp. 379-387
    • Fujino, H.1    Toyomura, K.2    Chen, X.B.3    Regan, J.W.4    Murayama, T.5
  • 68
    • 0035186865 scopus 로고    scopus 로고
    • Thalidomide and its analogues inhibit lipopolysaccharide-mediated induction of cyclooxygenase-2
    • Fujita, J., J. R. Mestre, J. B. Zeldis, K. Subbaramaiah and A. J. Dannenberg (2001). “Thalidomide and its analogues inhibit lipopolysaccharide-mediated induction of cyclooxygenase-2.” Clin Cancer Res 7(11): 3349-3355.
    • (2001) Clin Cancer Res , vol.7 , Issue.11 , pp. 3349-3355
    • Fujita, J.1    Mestre, J.R.2    Zeldis, J.B.3    Subbaramaiah, K.4    Dannenberg, A.J.5
  • 69
    • 0038375038 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1
    • Fukuda, R., B. Kelly and G. L. Semenza (2003). “Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1.” Cancer Res 63(9): 2330-2334.
    • (2003) Cancer Res , vol.63 , Issue.9 , pp. 2330-2334
    • Fukuda, R.1    Kelly, B.2    Semenza, G.L.3
  • 70
    • 0027361577 scopus 로고
    • Molecular biology in the eicosanoid field
    • Funk, C. D. (1993). “Molecular biology in the eicosanoid field.” Prog Nucleic Acid Res Mol Biol 45: 67-98.
    • (1993) Prog Nucleic Acid Res Mol Biol , vol.45 , pp. 67-98
    • Funk, C.D.1
  • 71
    • 0035976575 scopus 로고    scopus 로고
    • Prostaglandins and leukotrienes: Advances in eicosanoid biology
    • Funk, C. D. (2001). “Prostaglandins and leukotrienes: advances in eicosanoid biology.” Science 294(5548): 1871-1875.
    • (2001) Science , vol.294 , Issue.5548 , pp. 1871-1875
    • Funk, C.D.1
  • 72
    • 36348932768 scopus 로고    scopus 로고
    • COX-2 inhibitors and cardiovascular risk
    • Funk, C. D. and G. A. FitzGerald (2007). “COX-2 inhibitors and cardiovascular risk.” J Cardiovasc Pharmacol 50(5): 470-479.
    • (2007) J Cardiovasc Pharmacol , vol.50 , Issue.5 , pp. 470-479
    • Funk, C.D.1    FitzGerald, G.A.2
  • 74
    • 33749612562 scopus 로고    scopus 로고
    • What are cyclooxygenases and lipoxygenases doing in the driver’s seat of carcinogenesis?
    • Furstenberger, G., P. Krieg, K. Muller-Decker and A. J. Habenicht (2006). “What are cyclooxygenases and lipoxygenases doing in the driver’s seat of carcinogenesis?" Int J Cancer 119(10): 2247-2254.
    • (2006) Int J Cancer , vol.119 , Issue.10 , pp. 2247-2254
    • Furstenberger, G.1    Krieg, P.2    Muller-Decker, K.3    Habenicht, A.J.4
  • 76
    • 0028785372 scopus 로고
    • Elevated 12-lipoxygenase mRNA expression correlates with advanced stage and poor differentiation of human prostate cancer
    • Gao, X., D. J. Grignon, T. Chbihi, A. Zacharek, Y. Q. Chen, W. Sakr, A. T. Porter, J. D. Crissman, J. E. Pontes, I. J. Powell and et al. (1995). “Elevated 12-lipoxygenase mRNA expression correlates with advanced stage and poor differentiation of human prostate cancer.” Urology 46(2): 227-237.
    • (1995) Urology , vol.46 , Issue.2 , pp. 227-237
    • Gao, X.1    Grignon, D.J.2    Chbihi, T.3    Zacharek, A.4    Chen, Y.Q.5    Sakr, W.6    Porter, A.T.7    Crissman, J.D.8    Pontes, J.E.9    Powell, I.J.10
  • 77
    • 0034721883 scopus 로고    scopus 로고
    • Reversal of angiogenesis in vitro, induction of apoptosis, and inhibition of AKT phosphorylation in endothelial cells by thromboxane A(2)
    • Gao, Y., R. Yokota, S. Tang, A. W. Ashton and J. A. Ware (2000). “Reversal of angiogenesis in vitro, induction of apoptosis, and inhibition of AKT phosphorylation in endothelial cells by thromboxane A(2).” Circ Res 87(9): 739-745.
    • (2000) Circ Res , vol.87 , Issue.9 , pp. 739-745
    • Gao, Y.1    Yokota, R.2    Tang, S.3    Ashton, A.W.4    Ware, J.A.5
  • 78
    • 0242405617 scopus 로고    scopus 로고
    • Endothelial-pericyte interactions in angiogenesis
    • Gerhardt, H. and C. Betsholtz (2003). “Endothelial-pericyte interactions in angiogenesis.” Cell Tissue Res 314(1): 15-23.
    • (2003) Cell Tissue Res , vol.314 , Issue.1 , pp. 15-23
    • Gerhardt, H.1    Betsholtz, C.2
  • 79
  • 80
    • 0029100077 scopus 로고
    • Substrates for astrocytoma invasion
    • discussion 301-292
    • Giese, A., M. A. Loo, M. D. Rief, N. Tran and M. E. Berens (1995). “Substrates for astrocytoma invasion.” Neurosurgery 37(2): 294-301; discussion 301-292.
    • (1995) Neurosurgery , vol.37 , Issue.2 , pp. 294-301
    • Giese, A.1    Loo, M.A.2    Rief, M.D.3    Tran, N.4    Berens, M.E.5
  • 81
    • 0031667976 scopus 로고    scopus 로고
    • Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation
    • Gilroy, D. W., A. Tomlinson and D. A. Willoughby (1998). “Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation.” Eur J Pharmacol 355(2-3): 211-217.
    • (1998) Eur J Pharmacol , vol.355 , Issue.2-3 , pp. 211-217
    • Gilroy, D.W.1    Tomlinson, A.2    Willoughby, D.A.3
  • 82
    • 3142530344 scopus 로고    scopus 로고
    • 15-Lipoxygenase-2 expression in benign and neoplastic lung: An immunohistochemical study and correlation with tumor grade and proliferation
    • Gonzalez, A. L., R. L. Roberts, P. P. Massion, S. J. Olson, Y. Shyr and S. B. Shappell (2004). "15-Lipoxygenase-2 expression in benign and neoplastic lung: an immunohistochemical study and correlation with tumor grade and proliferation.” Hum Pathol 35(7): 840-849.
    • (2004) Hum Pathol , vol.35 , Issue.7 , pp. 840-849
    • Gonzalez, A.L.1    Roberts, R.L.2    Massion, P.P.3    Olson, S.J.4    Shyr, Y.5    Shappell, S.B.6
  • 83
    • 3442878955 scopus 로고    scopus 로고
    • Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: Evidence for a redox-sensitive peroxisome proliferator-activated receptor-gamma-independent mechanism
    • Grau, R., M. A. Iniguez and M. Fresno (2004). “Inhibition of activator protein 1 activation, vascular endothelial growth factor, and cyclooxygenase-2 expression by 15-deoxy-Delta12,14-prostaglandin J2 in colon carcinoma cells: evidence for a redox-sensitive peroxisome proliferator-activated receptor-gamma-independent mechanism.” Cancer Res 64(15): 5162-5171.
    • (2004) Cancer Res , vol.64 , Issue.15 , pp. 5162-5171
    • Grau, R.1    Iniguez, M.A.2    Fresno, M.3
  • 85
    • 79955558825 scopus 로고    scopus 로고
    • Biosynthesis of hemiketal eicosanoids by cross-over of the 5-lipoxygenase and cyclooxygenase-2 pathways
    • Griesser, M., T. Suzuki, N. Tejera, S. Mont, W. E. Boeglin, A. Pozzi and C. Schneider (2011). “Biosynthesis of hemiketal eicosanoids by cross-over of the 5-lipoxygenase and cyclooxygenase-2 pathways.” Proc Natl Acad Sci USA 108(17): 6945-6950.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.17 , pp. 6945-6950
    • Griesser, M.1    Suzuki, T.2    Tejera, N.3    Mont, S.4    Boeglin, W.E.5    Pozzi, A.6    Schneider, C.7
  • 86
    • 0034090097 scopus 로고    scopus 로고
    • Angiogenesis: Potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation
    • Griffioen, A. W. and G. Molema (2000). “Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation.” Pharmacol Rev 52(2): 237-268.
    • (2000) Pharmacol Rev , vol.52 , Issue.2 , pp. 237-268
    • Griffioen, A.W.1    Molema, G.2
  • 88
    • 0034700110 scopus 로고    scopus 로고
    • Prostacyclin mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer
    • Gupta, R. A., T. J., W. F. Krause, M. Geraci, T. M. Willson and S. K. Dey (2000). “Prostacyclin mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer.” Proc Natl Acad Sci USA 97: 13275-13280.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13275-13280
    • Gupta, R.A.T.J.1    Krause, W.F.2    Geraci, M.3    Willson, T.M.4    Dey, S.K.5
  • 90
    • 84355161712 scopus 로고    scopus 로고
    • The Angiogenic Switch for Vascular Endothelial Growth Factor-A and Cyclooxygenase-2 in Prostate Carcinoma: Correlation with Microvessel Density, Androgen Receptor Content and Gleson Grade
    • Gyftopoulos, K., K. Vourda, G. Sakellaropoulos, P. Perimenis, A. Athanasopoulos and E. Papadaki (2011). “The Angiogenic Switch for Vascular Endothelial Growth Factor-A and Cyclooxygenase-2 in Prostate Carcinoma: Correlation with Microvessel Density, Androgen Receptor Content and Gleson Grade.” Urol Int 87(4): 464-9.
    • (2011) Urol Int , vol.87 , Issue.4 , pp. 464-469
    • Gyftopoulos, K.1    Vourda, K.2    Sakellaropoulos, G.3    Perimenis, P.4    Athanasopoulos, A.5    Papadaki, E.6
  • 91
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan, D. and J. Folkman (1996). “Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis.” Cell 86(3): 353-364.
    • (1996) Cell , vol.86 , Issue.3 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 92
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D. and R. A. Weinberg (2011). “Hallmarks of cancer: the next generation.” Cell 144(5): 646-674.
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 93
    • 0028034970 scopus 로고
    • Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction
    • Harris, R. C., J. A. McKanna, Y. Akai, H. R. Jacobson, R. N. Dubois and M. D. Breyer (1994). “Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction.” J Clin Invest 94(6): 2504-2510.
    • (1994) J Clin Invest , vol.94 , Issue.6 , pp. 2504-2510
    • Harris, R.C.1    McKanna, J.A.2    Akai, Y.3    Jacobson, H.R.4    Dubois, R.N.5    Breyer, M.D.6
  • 94
    • 0036781173 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor gamma ligand 15-deoxy-Delta12,14-prostaglandin J2 induces vascular endothelial growth factor in the hormone-independent prostate cancer cell line PC 3 and the urinary bladder carcinoma cell line 5637
    • Haslmayer, P., T. Thalhammer, W. Jager, S. Aust, G. Steiner, C. Ensinger and P. Obrist (2002). “The peroxisome proliferator-activated receptor gamma ligand 15-deoxy-Delta12,14-prostaglandin J2 induces vascular endothelial growth factor in the hormone-independent prostate cancer cell line PC 3 and the urinary bladder carcinoma cell line 5637.” Int J Oncol 21(4): 915-920.
    • (2002) Int J Oncol , vol.21 , Issue.4 , pp. 915-920
    • Haslmayer, P.1    Thalhammer, T.2    Jager, W.3    Aust, S.4    Steiner, G.5    Ensinger, C.6    Obrist, P.7
  • 95
    • 4444262310 scopus 로고    scopus 로고
    • Pharmacology and signaling of prostaglandin receptors: Multiple roles in inflammation and immune modulation
    • Hata, A. N. and R. M. Breyer (2004). “Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation.” Pharmacol Ther 103(2): 147-166.
    • (2004) Pharmacol Ther , vol.103 , Issue.2 , pp. 147-166
    • Hata, A.N.1    Breyer, R.M.2
  • 96
    • 33748119839 scopus 로고    scopus 로고
    • Molecular modeling of the non-covalent binding of the dietary tomato carotenoids lycopene and lycophyll, and selected oxidative metabolites with 5-lipoxygenase
    • Hazai, E., Z. Bikadi, F. Zsila and S. F. Lockwood (2006). “Molecular modeling of the non-covalent binding of the dietary tomato carotenoids lycopene and lycophyll, and selected oxidative metabolites with 5-lipoxygenase.” Bioorg Med Chem 14(20): 6859-6867.
    • (2006) Bioorg Med Chem , vol.14 , Issue.20 , pp. 6859-6867
    • Hazai, E.1    Bikadi, Z.2    Zsila, F.3    Lockwood, S.F.4
  • 97
    • 48049084162 scopus 로고    scopus 로고
    • Angiogenic function of prostacyclin biosynthesis in human endothelial progenitor cells
    • He, T., T. Lu, L. V. d’Uscio, C. F. Lam, H. C. Lee and Z. S. Katusic (2008). “Angiogenic function of prostacyclin biosynthesis in human endothelial progenitor cells.” Circ Res 103(1): 80-88.
    • (2008) Circ Res , vol.103 , Issue.1 , pp. 80-88
    • He, T.1    Lu, T.2    d’Uscio, L.V.3    Lam, C.F.4    Lee, H.C.5    Katusic, Z.S.6
  • 99
    • 19844364244 scopus 로고    scopus 로고
    • Angiogenesis and lung cancer: Prognostic and therapeutic implications
    • Herbst, R. S., A. Onn and A. Sandler (2005). “Angiogenesis and lung cancer: prognostic and therapeutic implications.” J Clin Oncol 23(14): 3243-3256.
    • (2005) J Clin Oncol , vol.23 , Issue.14 , pp. 3243-3256
    • Herbst, R.S.1    Onn, A.2    Sandler, A.3
  • 100
    • 0035809312 scopus 로고    scopus 로고
    • Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: Roles of the nuclear factor of activated T cells and cyclooxygenase 2
    • Hernandez, G. L., O. V. Volpert, M. A. Iniguez, E. Lorenzo, S. Martinez-Martinez, R. Grau, M. Fresno and J. M. Redondo (2001). “Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2.” J Exp Med 193(5): 607-620.
    • (2001) J Exp Med , vol.193 , Issue.5 , pp. 607-620
    • Hernandez, G.L.1    Volpert, O.V.2    Iniguez, M.A.3    Lorenzo, E.4    Martinez-Martinez, S.5    Grau, R.6    Fresno, M.7    Redondo, J.M.8
  • 101
    • 0026730021 scopus 로고
    • Human cyclooxygenase-2 cDNA
    • Hla, T. and K. Neilson (1992). “Human cyclooxygenase-2 cDNA.” Proc Natl Acad Sci USA 89(16): 7384-7388.
    • (1992) Proc Natl Acad Sci USA , vol.89 , Issue.16 , pp. 7384-7388
    • Hla, T.1    Neilson, K.2
  • 102
    • 57649178299 scopus 로고    scopus 로고
    • 15-deoxy-Delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53
    • Ho, T. C., S. L. Chen, Y. C. Yang, C. Y. Chen, F. P. Feng, J. W. Hsieh, H. C. Cheng and Y. P. Tsao (2008). "15-deoxy-Delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53.” J Biol Chem 283(44): 30273-30288.
    • (2008) J Biol Chem , vol.283 , Issue.44 , pp. 30273-30288
    • Ho, T.C.1    Chen, S.L.2    Yang, Y.C.3    Chen, C.Y.4    Feng, F.P.5    Hsieh, J.W.6    Cheng, H.C.7    Tsao, Y.P.8
  • 103
    • 0033766398 scopus 로고    scopus 로고
    • COX-2 in brain and spinal cord implications for therapeutic use
    • Hoffmann, C. (2000). “COX-2 in brain and spinal cord implications for therapeutic use.” Curr Med Chem 7(11): 1113-1120.
    • (2000) Curr Med Chem , vol.7 , Issue.11 , pp. 1113-1120
    • Hoffmann, C.1
  • 104
    • 4544236324 scopus 로고    scopus 로고
    • Modulation of arachidonic acid metabolism by curcumin and related betadiketone derivatives: Effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase
    • Hong, J., M. Bose, J. Ju, J. H. Ryu, X. Chen, S. Sang, M. J. Lee and C. S. Yang (2004). “Modulation of arachidonic acid metabolism by curcumin and related betadiketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase.” Carcinogenesis 25(9): 1671-1679.
    • (2004) Carcinogenesis , vol.25 , Issue.9 , pp. 1671-1679
    • Hong, J.1    Bose, M.2    Ju, J.3    Ryu, J.H.4    Chen, X.5    Sang, S.6    Lee, M.J.7    Yang, C.S.8
  • 106
    • 0019798097 scopus 로고
    • Prostacyclin: A potent antimetastatic agent
    • Honn, K. V., B. Cicone and A. Skoff (1981). “Prostacyclin: a potent antimetastatic agent.” Science 212(4500): 1270-1272.
    • (1981) Science , vol.212 , Issue.4500 , pp. 1270-1272
    • Honn, K.V.1    Cicone, B.2    Skoff, A.3
  • 107
    • 0031302955 scopus 로고    scopus 로고
    • Prostaglandins induce vascular endothelial growth factor in a human monocytic cell line and rat lungs via cAMP
    • Hoper, M. M., N. F. Voelkel, T. O. Bates, J. D. Allard, M. Horan, D. Shepherd and R. M. Tuder (1997). “Prostaglandins induce vascular endothelial growth factor in a human monocytic cell line and rat lungs via cAMP.” Am J Respir Cell Mol Biol 17(6): 748-756.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , Issue.6 , pp. 748-756
    • Hoper, M.M.1    Voelkel, N.F.2    Bates, T.O.3    Allard, J.D.4    Horan, M.5    Shepherd, D.6    Tuder, R.M.7
  • 108
    • 34547867339 scopus 로고    scopus 로고
    • The lipoxygenase inhibitor, baicalein, modulates cell adhesion and migration by upregulation of integrins and vinculin in rat heart endothelial cells
    • Hsieh, Y. C., S. J. Hsieh, Y. S. Chang, C. M. Hsueh and S. L. Hsu (2007). “The lipoxygenase inhibitor, baicalein, modulates cell adhesion and migration by upregulation of integrins and vinculin in rat heart endothelial cells.” Br J Pharmacol 151(8): 1235-1245.
    • (2007) Br J Pharmacol , vol.151 , Issue.8 , pp. 1235-1245
    • Hsieh, Y.C.1    Hsieh, S.J.2    Chang, Y.S.3    Hsueh, C.M.4    Hsu, S.L.5
  • 109
    • 17744386137 scopus 로고    scopus 로고
    • Cyclooxygenase-2 increases hypoxia-inducible factor-1 and vascular endothelial growth factor to promote angiogenesis in gastric carcinoma
    • Huang, S. P., M. S. Wu, C. T. Shun, H. P. Wang, C. Y. Hsieh, M. L. Kuo and J. T. Lin (2005). “Cyclooxygenase-2 increases hypoxia-inducible factor-1 and vascular endothelial growth factor to promote angiogenesis in gastric carcinoma.” J Biomed Sci 12(1): 229-241.
    • (2005) J Biomed Sci , vol.12 , Issue.1 , pp. 229-241
    • Huang, S.P.1    Wu, M.S.2    Shun, C.T.3    Wang, H.P.4    Hsieh, C.Y.5    Kuo, M.L.6    Lin, J.T.7
  • 110
    • 0024539731 scopus 로고
    • Evidence for prostanoid biosynthesis as a biochemical feature of certain subclasses of non-small cell carcinomas of the lung as determined in established cell lines derived from human lung tumors
    • Hubbard, W. C., M. C. Alley, G. N. Gray, K. C. Green, T. L. McLemore and M. R. Boyd (1989). “Evidence for prostanoid biosynthesis as a biochemical feature of certain subclasses of non-small cell carcinomas of the lung as determined in established cell lines derived from human lung tumors.” Cancer Res 49(4): 826-832.
    • (1989) Cancer Res , vol.49 , Issue.4 , pp. 826-832
    • Hubbard, W.C.1    Alley, M.C.2    Gray, G.N.3    Green, K.C.4    McLemore, T.L.5    Boyd, M.R.6
  • 114
    • 43449100392 scopus 로고    scopus 로고
    • The effects of cyclooxygenase2-prostaglandinE2 pathway on Helicobacter pyloriinduced urokinase-type plasminogen activator system in the gastric cancer cells
    • Iwamoto, J., Y. Mizokami, K. Takahashi, T. Matsuoka and Y. Matsuzaki (2008). “The effects of cyclooxygenase2-prostaglandinE2 pathway on Helicobacter pyloriinduced urokinase-type plasminogen activator system in the gastric cancer cells.” Helicobacter 13(3): 174-182.
    • (2008) Helicobacter , vol.13 , Issue.3 , pp. 174-182
    • Iwamoto, J.1    Mizokami, Y.2    Takahashi, K.3    Matsuoka, T.4    Matsuzaki, Y.5
  • 115
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • Jain, R. K. (2003). “Molecular regulation of vessel maturation.” Nat Med 9(6): 685-693.
    • (2003) Nat Med , vol.9 , Issue.6 , pp. 685-693
    • Jain, R.K.1
  • 116
    • 0030669894 scopus 로고    scopus 로고
    • Quantitative angiogenesis assays: Progress and problems
    • Jain, R. K., K. Schlenger, M. Hockel and F. Yuan (1997). “Quantitative angiogenesis assays: progress and problems.” Nat Med 3(11): 1203-1208.
    • (1997) Nat Med , vol.3 , Issue.11 , pp. 1203-1208
    • Jain, R.K.1    Schlenger, K.2    Hockel, M.3    Yuan, F.4
  • 118
    • 2442633329 scopus 로고    scopus 로고
    • Inhibition of the arachidonic acid metabolism blocks endothelial cell migration and induces apoptosis
    • Jantke, J., M. Ladehoff, F. Kurzel, S. Zapf, E. Kim and A. Giese (2004). “Inhibition of the arachidonic acid metabolism blocks endothelial cell migration and induces apoptosis.” Acta Neurochir (Wien) 146(5): 483-494.
    • (2004) Acta Neurochir (Wien) , vol.146 , Issue.5 , pp. 483-494
    • Jantke, J.1    Ladehoff, M.2    Kurzel, F.3    Zapf, S.4    Kim, E.5    Giese, A.6
  • 120
    • 0345304870 scopus 로고    scopus 로고
    • Levels of expression of lipoxygenases and cyclooxygenase-2 in human breast cancer
    • Jiang, W. G., A. Douglas-Jones and R. E. Mansel (2003). “Levels of expression of lipoxygenases and cyclooxygenase-2 in human breast cancer.” Prostaglandins Leukot Essent Fatty Acids 69(4): 275-281.
    • (2003) Prostaglandins Leukot Essent Fatty Acids , vol.69 , Issue.4 , pp. 275-281
    • Jiang, W.G.1    Douglas-Jones, A.2    Mansel, R.E.3
  • 121
    • 30544440084 scopus 로고    scopus 로고
    • Aberrant expression of 5-lipoxygenase-activating protein (5-LOXAP) has prognostic and survival significance in patients with breast cancer
    • Jiang, W. G., A. G. Douglas-Jones and R. E. Mansel (2006). “Aberrant expression of 5-lipoxygenase-activating protein (5-LOXAP) has prognostic and survival significance in patients with breast cancer.” Prostaglandins Leukot Essent Fatty Acids 74(2): 125-134.
    • (2006) Prostaglandins Leukot Essent Fatty Acids , vol.74 , Issue.2 , pp. 125-134
    • Jiang, W.G.1    Douglas-Jones, A.G.2    Mansel, R.E.3
  • 122
  • 123
    • 0027468941 scopus 로고
    • Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines
    • Jones, D. A., D. P. Carlton, T. M. McIntyre, G. A. Zimmerman and S. M. Prescott (1993). “Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines.” J Biol Chem 268(12): 9049-9054.
    • (1993) J Biol Chem , vol.268 , Issue.12 , pp. 9049-9054
    • Jones, D.A.1    Carlton, D.P.2    McIntyre, T.M.3    Zimmerman, G.A.4    Prescott, S.M.5
  • 124
    • 0032750920 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing
    • Jones, M. K., H. Wang, B. M. Peskar, E. Levin, R. M. Itani, I. J. Sarfeh and A. S. Tarnawski (1999). “Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing.” Nat Med 5(12): 1418-1423.
    • (1999) Nat Med , vol.5 , Issue.12 , pp. 1418-1423
    • Jones, M.K.1    Wang, H.2    Peskar, B.M.3    Levin, E.4    Itani, R.M.5    Sarfeh, I.J.6    Tarnawski, A.S.7
  • 125
    • 33846805646 scopus 로고    scopus 로고
    • Enhancement of glioblastoma radioresponse by a selective COX-2 inhibitor celecoxib: Inhibition of tumor angiogenesis with extensive tumor necrosis
    • Kang, K. B., T. T. Wang, C. T. Woon, E. S. Cheah, X. L. Moore, C. Zhu and M. C. Wong (2007). “Enhancement of glioblastoma radioresponse by a selective COX-2 inhibitor celecoxib: inhibition of tumor angiogenesis with extensive tumor necrosis.” Int J Radiat Oncol Biol Phys 67(3): 888-896.
    • (2007) Int J Radiat Oncol Biol Phys , vol.67 , Issue.3 , pp. 888-896
    • Kang, K.B.1    Wang, T.T.2    Woon, C.T.3    Cheah, E.S.4    Moore, X.L.5    Zhu, C.6    Wong, M.C.7
  • 126
    • 34250685667 scopus 로고    scopus 로고
    • Zebrafish: An emerging model system for human disease and drug discovery
    • Kari, G., U. Rodeck and A. P. Dicker (2007). “Zebrafish: an emerging model system for human disease and drug discovery.” Clin Pharmacol Ther 82(1): 70-80.
    • (2007) Clin Pharmacol Ther , vol.82 , Issue.1 , pp. 70-80
    • Kari, G.1    Rodeck, U.2    Dicker, A.P.3
  • 127
    • 77950916848 scopus 로고    scopus 로고
    • Inhalation of an ethanol-based zileuton formulation provides a reduction of pulmonary adenomas in the A/J mouse model
    • Karlage, K. L., E. Mogalian, A. Jensen and P. B. Myrdal (2010). “Inhalation of an ethanol-based zileuton formulation provides a reduction of pulmonary adenomas in the A/J mouse model.” AAPS PharmSciTech 11(1): 168-173.
    • (2010) AAPS PharmSciTech , vol.11 , Issue.1 , pp. 168-173
    • Karlage, K.L.1    Mogalian, E.2    Jensen, A.3    Myrdal, P.B.4
  • 128
    • 0033783018 scopus 로고    scopus 로고
    • Concordant induction of 15-lipoxygenase-1 and mutant p53 expression in human prostate adenocarcinoma: Correlation with Gleason staging
    • Kelavkar, U. P., C. Cohen, H. Kamitani, T. E. Eling and K. F. Badr (2000). “Concordant induction of 15-lipoxygenase-1 and mutant p53 expression in human prostate adenocarcinoma: correlation with Gleason staging.” Carcinogenesis 21(10): 1777-1787.
    • (2000) Carcinogenesis , vol.21 , Issue.10 , pp. 1777-1787
    • Kelavkar, U.P.1    Cohen, C.2    Kamitani, H.3    Eling, T.E.4    Badr, K.F.5
  • 130
    • 0034131079 scopus 로고    scopus 로고
    • ‘Accidental’ antiangiogenic drugs. anti-oncogene directed signal transduction inhibitors and conventional chemotherapeutic agents as examples
    • Kerbel, R. S., A. Viloria-Petit, G. Klement and J. Rak (2000). "‘Accidental’ antiangiogenic drugs. anti-oncogene directed signal transduction inhibitors and conventional chemotherapeutic agents as examples.” Eur J Cancer 36(10): 1248-1257.
    • (2000) Eur J Cancer , vol.36 , Issue.10 , pp. 1248-1257
    • Kerbel, R.S.1    Viloria-Petit, A.2    Klement, G.3    Rak, J.4
  • 132
    • 0034901568 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer
    • Khuri, F. R., H. Wu, J. J. Lee, B. L. Kemp, R. Lotan, S. M. Lippman, L. Feng, W. K. Hong and X. C. Xu (2001). “Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer.” Clin Cancer Res 7(4): 861-867.
    • (2001) Clin Cancer Res , vol.7 , Issue.4 , pp. 861-867
    • Khuri, F.R.1    Wu, H.2    Lee, J.J.3    Kemp, B.L.4    Lotan, R.5    Lippman, S.M.6    Feng, L.7    Hong, W.K.8    Xu, X.C.9
  • 133
    • 77952549595 scopus 로고    scopus 로고
    • Acrolein increases 5-lipoxygenase expression in murine macrophages through activation of ERK pathway
    • Kim, C. E., S. J. Lee, K. W. Seo, H. M. Park, J. W. Yun, J. U. Bae, S. S. Bae and C. D. Kim (2010). “Acrolein increases 5-lipoxygenase expression in murine macrophages through activation of ERK pathway.” Toxicol Appl Pharmacol 245(1): 76-82.
    • (2010) Toxicol Appl Pharmacol , vol.245 , Issue.1 , pp. 76-82
    • Kim, C.E.1    Lee, S.J.2    Seo, K.W.3    Park, H.M.4    Yun, J.W.5    Bae, J.U.6    Bae, S.S.7    Kim, C.D.8
  • 134
    • 66349135079 scopus 로고    scopus 로고
    • Role of the low-affinity leukotriene B4 receptor BLT2 in VEGF-induced angiogenesis
    • Kim, G. Y., J. W. Lee, S. H. Cho, J. M. Seo and J. H. Kim (2009). “Role of the low-affinity leukotriene B4 receptor BLT2 in VEGF-induced angiogenesis.” Arterioscler Thromb Vasc Biol 29(6): 915-920.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , Issue.6 , pp. 915-920
    • Kim, G.Y.1    Lee, J.W.2    Cho, S.H.3    Seo, J.M.4    Kim, J.H.5
  • 135
    • 0142011063 scopus 로고    scopus 로고
    • Correlation between cyclooxygenase-2 and tumor angiogenesis in non-small cell lung cancer
    • Kim, H. S., H. R. Youm, J. S. Lee, K. W. Min, J. H. Chung and C. S. Park (2003). “Correlation between cyclooxygenase-2 and tumor angiogenesis in non-small cell lung cancer.” Lung Cancer 42(2): 163-170.
    • (2003) Lung Cancer , vol.42 , Issue.2 , pp. 163-170
    • Kim, H.S.1    Youm, H.R.2    Lee, J.S.3    Min, K.W.4    Chung, J.H.5    Park, C.S.6
  • 138
    • 0030679720 scopus 로고    scopus 로고
    • Fatty acids and colon cancer in experimental models
    • Klurfeld, D. M. and A. W. Bull (1997). “Fatty acids and colon cancer in experimental models.” Am J Clin Nutr 66(6 Suppl): 1530S-1538S.
    • (1997) Am J Clin Nutr , vol.66 , Issue.6 , pp. 1530S-1538S
    • Klurfeld, D.M.1    Bull, A.W.2
  • 139
    • 68849095477 scopus 로고    scopus 로고
    • Curcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1
    • Koeberle, A., H. Northoff and O. Werz (2009). “Curcumin blocks prostaglandin E2 biosynthesis through direct inhibition of the microsomal prostaglandin E2 synthase-1.” Mol Cancer Ther 8(8): 2348-2355.
    • (2009) Mol Cancer Ther , vol.8 , Issue.8 , pp. 2348-2355
    • Koeberle, A.1    Northoff, H.2    Werz, O.3
  • 140
    • 34648832065 scopus 로고    scopus 로고
    • Prognostic significance of VEGF expression in correlation with COX-2, microvessel density, and clinicopathological characteristics in human gastric carcinoma
    • Kolev, Y., H. Uetake, S. Iida, T. Ishikawa, T. Kawano and K. Sugihara (2007). “Prognostic significance of VEGF expression in correlation with COX-2, microvessel density, and clinicopathological characteristics in human gastric carcinoma.” Ann Surg Oncol 14(10): 2738-2747.
    • (2007) Ann Surg Oncol , vol.14 , Issue.10 , pp. 2738-2747
    • Kolev, Y.1    Uetake, H.2    Iida, S.3    Ishikawa, T.4    Kawano, T.5    Sugihara, K.6
  • 143
  • 144
    • 4644337725 scopus 로고    scopus 로고
    • Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in nonsmall cell lung cancer
    • Krysan, K., H. Dalwadi, S. Sharma, M. Pold and S. Dubinett (2004). “Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in nonsmall cell lung cancer.” Cancer Res 64(18): 6359-6362.
    • (2004) Cancer Res , vol.64 , Issue.18 , pp. 6359-6362
    • Krysan, K.1    Dalwadi, H.2    Sharma, S.3    Pold, M.4    Dubinett, S.5
  • 145
    • 0036669583 scopus 로고    scopus 로고
    • Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications
    • Kuhn, H., M. Walther and R. J. Kuban (2002). “Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications.” Prostaglandins Other Lipid Mediat 68-69: 263-290.
    • (2002) Prostaglandins Other Lipid Mediat , vol.68-69 , pp. 263-290
    • Kuhn, H.1    Walther, M.2    Kuban, R.J.3
  • 147
    • 0035073949 scopus 로고    scopus 로고
    • Cyclo-oxygenase and lipoxygenase pathways in mast cell dependent-neurogenic inflammation induced by electrical stimulation of the rat saphenous nerve
    • Le Filliatre, G., S. Sayah, V. Latournerie, J. F. Renaud, M. Finet and R. Hanf (2001). “Cyclo-oxygenase and lipoxygenase pathways in mast cell dependent-neurogenic inflammation induced by electrical stimulation of the rat saphenous nerve.” Br J Pharmacol 132(7): 1581-1589.
    • (2001) Br J Pharmacol , vol.132 , Issue.7 , pp. 1581-1589
    • Le Filliatre, G.1    Sayah, S.2    Latournerie, V.3    Renaud, J.F.4    Finet, M.5    Hanf, R.6
  • 148
    • 0033755146 scopus 로고    scopus 로고
    • Role of cyclooxygenases in angiogenesis
    • Leahy, K. M., A. T. Koki and J. L. Masferrer (2000). “Role of cyclooxygenases in angiogenesis.” Curr Med Chem 7(11): 1163-1170.
    • (2000) Curr Med Chem , vol.7 , Issue.11 , pp. 1163-1170
    • Leahy, K.M.1    Koki, A.T.2    Masferrer, J.L.3
  • 149
    • 0036468287 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo
    • Leahy, K. M., R. L. Ornberg, Y. Wang, B. S. Zweifel, A. T. Koki and J. L. Masferrer (2002). “Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo.” Cancer Res 62(3): 625-631.
    • (2002) Cancer Res , vol.62 , Issue.3 , pp. 625-631
    • Leahy, K.M.1    Ornberg, R.L.2    Wang, Y.3    Zweifel, B.S.4    Koki, A.T.5    Masferrer, J.L.6
  • 151
    • 67651040709 scopus 로고    scopus 로고
    • Effects of a cyclooxygenase-1-selective inhibitor in a mouse model of ovarian cancer, administered alone or in combination with ibuprofen, a nonselective cyclooxygenase inhibitor
    • Li, W., R. J. Xu, Z. Y. Lin, G. C. Zhuo and H. H. Zhang (2009). “Effects of a cyclooxygenase-1-selective inhibitor in a mouse model of ovarian cancer, administered alone or in combination with ibuprofen, a nonselective cyclooxygenase inhibitor.” Med Oncol 26(2): 170-177.
    • (2009) Med Oncol , vol.26 , Issue.2 , pp. 170-177
    • Li, W.1    Xu, R.J.2    Lin, Z.Y.3    Zhuo, G.C.4    Zhang, H.H.5
  • 152
    • 79960666903 scopus 로고    scopus 로고
    • Baicalein potently suppresses angiogenesis induced by vascular endothelial growth factor through the p53/Rb signaling pathway leading to G1/S cell cycle arrest
    • Ling, Y., Y. Chen, P. Chen, H. Hui, X. Song, Z. Lu, C. Li, N. Lu and Q. Guo (2011). “Baicalein potently suppresses angiogenesis induced by vascular endothelial growth factor through the p53/Rb signaling pathway leading to G1/S cell cycle arrest.” Exp Biol Med (Maywood) 236(7): 851-858.
    • (2011) Exp Biol Med (Maywood) , vol.236 , Issue.7 , pp. 851-858
    • Ling, Y.1    Chen, Y.2    Chen, P.3    Hui, H.4    Song, X.5    Lu, Z.6    Li, C.7    Lu, N.8    Guo, Q.9
  • 153
    • 0043095357 scopus 로고    scopus 로고
    • Baicalein and baicalin are potent inhibitors of angiogenesis: Inhibition of endothelial cell proliferation, migration and differentiation
    • Liu, J. J., T. S. Huang, W. F. Cheng and F. J. Lu (2003). “Baicalein and baicalin are potent inhibitors of angiogenesis: Inhibition of endothelial cell proliferation, migration and differentiation.” Int J Cancer 106(4): 559-565.
    • (2003) Int J Cancer , vol.106 , Issue.4 , pp. 559-565
    • Liu, J.J.1    Huang, T.S.2    Cheng, W.F.3    Lu, F.J.4
  • 154
    • 0141765733 scopus 로고    scopus 로고
    • Coordinate activation of HIF-1 and NF-kappaB DNA binding and COX-2 and VEGF expression in retinal cells by hypoxia
    • Lukiw, W. J., A. Ottlecz, G. Lambrou, M. Grueninger, J. Finley, H. W. Thompson and N. G. Bazan (2003). “Coordinate activation of HIF-1 and NF-kappaB DNA binding and COX-2 and VEGF expression in retinal cells by hypoxia.” Invest Ophthalmol Vis Sci 44(10): 4163-4170.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , Issue.10 , pp. 4163-4170
    • Lukiw, W.J.1    Ottlecz, A.2    Lambrou, G.3    Grueninger, M.4    Finley, J.5    Thompson, H.W.6    Bazan, N.G.7
  • 155
    • 80053574010 scopus 로고    scopus 로고
    • Key role of 15-lipoxygenase/15-hydroxyeicosatetraenoic acid in pulmonary vascular remodeling and vascular angiogenesis associated with hypoxic pulmonary hypertension
    • Ma, C., Y. Li, J. Ma, Y. Liu, Q. Li, S. Niu, Z. Shen, L. Zhang, Z. Pan and D. Zhu (2011). “Key role of 15-lipoxygenase/15-hydroxyeicosatetraenoic acid in pulmonary vascular remodeling and vascular angiogenesis associated with hypoxic pulmonary hypertension.” Hypertension 58(4): 679-688.
    • (2011) Hypertension , vol.58 , Issue.4 , pp. 679-688
    • Ma, C.1    Li, Y.2    Ma, J.3    Liu, Y.4    Li, Q.5    Niu, S.6    Shen, Z.7    Zhang, L.8    Pan, Z.9    Zhu, D.10
  • 156
    • 0036792055 scopus 로고    scopus 로고
    • Divergent effects of new cyclooxygenase inhibitors on gastric ulcer healing: Shifting the angiogenic balance
    • Ma, L., P. del Soldato and J. L. Wallace (2002). “Divergent effects of new cyclooxygenase inhibitors on gastric ulcer healing: Shifting the angiogenic balance.” Proc Natl Acad Sci USA 99(20): 13243-13247.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.20 , pp. 13243-13247
    • Ma, L.1    del Soldato, P.2    Wallace, J.L.3
  • 157
    • 0031816247 scopus 로고    scopus 로고
    • Collagenase-3 induction in rat lung fibroblasts requires the combined effects of tumor necrosis factor-alpha and 12-lipoxygenase metabolites: A model of macrophage-induced, fibroblast-driven extracellular matrix remodeling during inflammatory lung injury
    • Mariani, T. J., S. Sandefur, J. D. Roby and R. A. Pierce (1998). “Collagenase-3 induction in rat lung fibroblasts requires the combined effects of tumor necrosis factor-alpha and 12-lipoxygenase metabolites: a model of macrophage-induced, fibroblast-driven extracellular matrix remodeling during inflammatory lung injury.” Mol Biol Cell 9(6): 1411-1424.
    • (1998) Mol Biol Cell , vol.9 , Issue.6 , pp. 1411-1424
    • Mariani, T.J.1    Sandefur, S.2    Roby, J.D.3    Pierce, R.A.4
  • 160
    • 33645912341 scopus 로고    scopus 로고
    • Vascular endothelial growth factor production in human prostate cancer cells is stimulated by overexpression of platelet 12-lipoxygenase
    • McCabe, N. P., S. H. Selman and J. Jankun (2006). “Vascular endothelial growth factor production in human prostate cancer cells is stimulated by overexpression of platelet 12-lipoxygenase.” Prostate 66(7): 779-787.
    • (2006) Prostate , vol.66 , Issue.7 , pp. 779-787
    • McCabe, N.P.1    Selman, S.H.2    Jankun, J.3
  • 161
    • 0031809006 scopus 로고    scopus 로고
    • Altered gene expression in human astrocytoma cells selected for migration: I. Thromboxane synthase
    • McDonough, W., N. Tran, A. Giese, S. A. Norman and M. E. Berens (1998). “Altered gene expression in human astrocytoma cells selected for migration: I. Thromboxane synthase.” J Neuropathol Exp Neurol 57(5): 449-455.
    • (1998) J Neuropathol Exp Neurol , vol.57 , Issue.5 , pp. 449-455
    • McDonough, W.1    Tran, N.2    Giese, A.3    Norman, S.A.4    Berens, M.E.5
  • 164
    • 11144261691 scopus 로고    scopus 로고
    • Increased endothelial uptake of paclitaxel as a potential mechanism for its antiangiogenic effects: Potentiation by Cox-2 inhibition
    • Merchan, J. R., D. R. Jayaram, J. G. Supko, X. He, G. J. Bubley and V. P. Sukhatme (2005). “Increased endothelial uptake of paclitaxel as a potential mechanism for its antiangiogenic effects: potentiation by Cox-2 inhibition.” Int J Cancer 113(3): 490-498.
    • (2005) Int J Cancer , vol.113 , Issue.3 , pp. 490-498
    • Merchan, J.R.1    Jayaram, D.R.2    Supko, J.G.3    He, X.4    Bubley, G.J.5    Sukhatme, V.P.6
  • 165
    • 0347753697 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptors and cancers: Complex stories
    • Michalik, L., B. Desvergne and W. Wahli (2004). “Peroxisome-proliferator-activated receptors and cancers: complex stories.” Nat Rev Cancer 4(1): 61-70.
    • (2004) Nat Rev Cancer , vol.4 , Issue.1 , pp. 61-70
    • Michalik, L.1    Desvergne, B.2    Wahli, W.3
  • 166
    • 0035865363 scopus 로고    scopus 로고
    • Redefining the target: Chemotherapeutics as antiangiogenics
    • Miller, K. D., C. J. Sweeney and G. W. Sledge, Jr. (2001). “Redefining the target: chemotherapeutics as antiangiogenics.” J Clin Oncol 19(4): 1195-1206.
    • (2001) J Clin Oncol , vol.19 , Issue.4 , pp. 1195-1206
    • Miller, K.D.1    Sweeney, C.J.2    Sledge, G.W.3
  • 168
    • 13844275122 scopus 로고    scopus 로고
    • Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes
    • Moon, C., M. Ahn, M. B. Wie, H. M. Kim, C. S. Koh, S. C. Hong, M. D. Kim, N. Tanuma, Y. Matsumoto and T. Shin (2005). “Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes.” Brain Res 1035(2): 206-210.
    • (2005) Brain Res , vol.1035 , Issue.2 , pp. 206-210
    • Moon, C.1    Ahn, M.2    Wie, M.B.3    Kim, H.M.4    Koh, C.S.5    Hong, S.C.6    Kim, M.D.7    Tanuma, N.8    Matsumoto, Y.9    Shin, T.10
  • 169
    • 0033997088 scopus 로고    scopus 로고
    • Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2
    • Morteau, O., S. G. Morham, R. Sellon, L. A. Dieleman, R. Langenbach, O. Smithies and R. B. Sartor (2000). “Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2.” J Clin Invest 105(4): 469-478.
    • (2000) J Clin Invest , vol.105 , Issue.4 , pp. 469-478
    • Morteau, O.1    Morham, S.G.2    Sellon, R.3    Dieleman, L.A.4    Langenbach, R.5    Smithies, O.6    Sartor, R.B.7
  • 171
    • 29244451423 scopus 로고    scopus 로고
    • Prognostic and functional significance of thromboxane synthase gene overexpression in invasive bladder cancer
    • Moussa, O., J. S. Yordy, H. Abol-Enein, D. Sinha, N. K. Bissada, P. V. Halushka, M. A. Ghoneim and D. K. Watson (2005). “Prognostic and functional significance of thromboxane synthase gene overexpression in invasive bladder cancer.” Cancer Res 65(24): 11581-11587.
    • (2005) Cancer Res , vol.65 , Issue.24 , pp. 11581-11587
    • Moussa, O.1    Yordy, J.S.2    Abol-Enein, H.3    Sinha, D.4    Bissada, N.K.5    Halushka, P.V.6    Ghoneim, M.A.7    Watson, D.K.8
  • 173
    • 0031974158 scopus 로고    scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin
    • Murohara, T., J. R. Horowitz, M. Silver, Y. Tsurumi, D. Chen, A. Sullivan and J. M. Isner (1998). “Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin.” Circulation 97(1): 99-107.
    • (1998) Circulation , vol.97 , Issue.1 , pp. 99-107
    • Murohara, T.1    Horowitz, J.R.2    Silver, M.3    Tsurumi, Y.4    Chen, D.5    Sullivan, A.6    Isner, J.M.7
  • 174
    • 0035406938 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces cyclooxygenase-dependent proliferation of endothelial cells via the VEGF-2 receptor
    • Murphy, J. F. and D. J. Fitzgerald (2001). “Vascular endothelial growth factor induces cyclooxygenase-dependent proliferation of endothelial cells via the VEGF-2 receptor.” Faseb J 15(9): 1667-1669.
    • (2001) Faseb J , vol.15 , Issue.9 , pp. 1667-1669
    • Murphy, J.F.1    Fitzgerald, D.J.2
  • 175
    • 14644399741 scopus 로고    scopus 로고
    • Engagement of CD44 modulates cyclooxygenase induction, VEGF generation, and proliferation in human vascular endothelial cells
    • Murphy, J. F., F. Lennon, C. Steele, D. Kelleher, D. Fitzgerald and A. C. Long (2005). “Engagement of CD44 modulates cyclooxygenase induction, VEGF generation, and proliferation in human vascular endothelial cells.” Faseb J 19(3): 446-448.
    • (2005) Faseb J , vol.19 , Issue.3 , pp. 446-448
    • Murphy, J.F.1    Lennon, F.2    Steele, C.3    Kelleher, D.4    Fitzgerald, D.5    Long, A.C.6
  • 176
    • 0037394105 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-1 and -2 modulates angiogenic responses to engagement of alphavbeta3
    • Murphy, J. F., C. Steele, O. Belton and D. J. Fitzgerald (2003). “Induction of cyclooxygenase-1 and -2 modulates angiogenic responses to engagement of alphavbeta3.” Br J Haematol 121(1): 157-164.
    • (2003) Br J Haematol , vol.121 , Issue.1 , pp. 157-164
    • Murphy, J.F.1    Steele, C.2    Belton, O.3    Fitzgerald, D.J.4
  • 177
    • 63549109593 scopus 로고    scopus 로고
    • A phase II study of celecoxib in combination with paclitaxel, carboplatin, and radiotherapy for patients with inoperable stage IIIA/B non-small cell lung cancer
    • Mutter, R., B. Lu, D. P. Carbone, I. Csiki, L. Moretti, D. H. Johnson, J. D. Morrow, A. B. Sandler, Y. Shyr, F. Ye and H. Choy (2009). “A phase II study of celecoxib in combination with paclitaxel, carboplatin, and radiotherapy for patients with inoperable stage IIIA/B non-small cell lung cancer.” Clin Cancer Res 15(6): 2158-2165.
    • (2009) Clin Cancer Res , vol.15 , Issue.6 , pp. 2158-2165
    • Mutter, R.1    Lu, B.2    Carbone, D.P.3    Csiki, I.4    Moretti, L.5    Johnson, D.H.6    Morrow, J.D.7    Sandler, A.B.8    Shyr, Y.9    Ye, F.10    Choy, H.11
  • 178
    • 34447094488 scopus 로고    scopus 로고
    • Effects of novel 5-lipoxygenase inhibitors on the incidence of pulmonary adenomas in the A/J murine model when administered via nose-only inhalation
    • Myrdal, P. B., K. Karlage, P. J. Kuehl, B. S. Angersbach, B. A. Merrill and P. D. Wightman (2007). “Effects of novel 5-lipoxygenase inhibitors on the incidence of pulmonary adenomas in the A/J murine model when administered via nose-only inhalation.” Carcinogenesis 28(5): 957-961.
    • (2007) Carcinogenesis , vol.28 , Issue.5 , pp. 957-961
    • Myrdal, P.B.1    Karlage, K.2    Kuehl, P.J.3    Angersbach, B.S.4    Merrill, B.A.5    Wightman, P.D.6
  • 179
    • 0037055533 scopus 로고    scopus 로고
    • Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer
    • Nagatsuka, I., N. Yamada, S. Shimizu, M. Ohira, H. Nishino, S. Seki and K. Hirakawa (2002). “Inhibitory effect of a selective cyclooxygenase-2 inhibitor on liver metastasis of colon cancer.” Int J Cancer 100(5): 515-519.
    • (2002) Int J Cancer , vol.100 , Issue.5 , pp. 515-519
    • Nagatsuka, I.1    Yamada, N.2    Shimizu, S.3    Ohira, M.4    Nishino, H.5    Seki, S.6    Hirakawa, K.7
  • 180
    • 0034931501 scopus 로고    scopus 로고
    • Genetic and pharmacological analysis of prostanoid receptor function
    • Narumiya, S. and G. A. FitzGerald (2001). “Genetic and pharmacological analysis of prostanoid receptor function.” J Clin Invest 108(1): 25-30.
    • (2001) J Clin Invest , vol.108 , Issue.1 , pp. 25-30
    • Narumiya, S.1    FitzGerald, G.A.2
  • 181
    • 0020431791 scopus 로고
    • Histotypic angiogenesis in vitro: Light microscopic, ultrastructural, and radioautographic studies
    • Nicosia, R. F., R. Tchao and J. Leighton (1982). “Histotypic angiogenesis in vitro: light microscopic, ultrastructural, and radioautographic studies.” In vitro 18(6): 538-549.
    • (1982) Vitro , vol.18 , Issue.6 , pp. 538-549
    • Nicosia, R.F.1    Tchao, R.2    Leighton, J.3
  • 182
    • 34249791166 scopus 로고    scopus 로고
    • Cyclooxygenases and lipoxygenases in prostate and breast cancers
    • Nie, D. (2007). “Cyclooxygenases and lipoxygenases in prostate and breast cancers.” Front Biosci 12: 1574-1585.
    • (2007) Front Biosci , vol.12 , pp. 1574-1585
    • Nie, D.1
  • 188
    • 0034176036 scopus 로고    scopus 로고
    • Eicosanoid regulation of angiogenesis: Role of endothelial arachidonate 12-lipoxygenase
    • Nie, D., K. Tang, C. Diglio and K. V. Honn (2000). “Eicosanoid regulation of angiogenesis: role of endothelial arachidonate 12-lipoxygenase.” Blood 95(7): 2304-2311.
    • (2000) Blood , vol.95 , Issue.7 , pp. 2304-2311
    • Nie, D.1    Tang, K.2    Diglio, C.3    Honn, K.V.4
  • 189
    • 33644648950 scopus 로고    scopus 로고
    • Elevated 12-and 20-hydroxyeicosatetraenoic acid in urine of patients with prostatic diseases
    • Nithipatikom, K., M. A. Isbell, W. A. See and W. B. Campbell (2006). “Elevated 12-and 20-hydroxyeicosatetraenoic acid in urine of patients with prostatic diseases.” Cancer Lett 233(2): 219-225.
    • (2006) Cancer Lett , vol.233 , Issue.2 , pp. 219-225
    • Nithipatikom, K.1    Isbell, M.A.2    See, W.A.3    Campbell, W.B.4
  • 191
    • 3042750458 scopus 로고    scopus 로고
    • The quest for new cysteinyl-leukotriene and lipoxin receptors: Recent clues
    • Norel, X. and C. Brink (2004). “The quest for new cysteinyl-leukotriene and lipoxin receptors: recent clues.” Pharmacol Ther 103(1): 81-94.
    • (2004) Pharmacol Ther , vol.103 , Issue.1 , pp. 81-94
    • Norel, X.1    Brink, C.2
  • 192
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • O’Reilly, M. S., L. Holmgren, Y. Shing, C. Chen, R. A. Rosenthal, M. Moses, W. S. Lane, Y. Cao, E. H. Sage and J. Folkman (1994). “Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma.” Cell 79(2): 315-328.
    • (1994) Cell , vol.79 , Issue.2 , pp. 315-328
    • O’Reilly, M.S.1    Holmgren, L.2    Shing, Y.3    Chen, C.4    Rosenthal, R.A.5    Moses, M.6    Lane, W.S.7    Cao, Y.8    Sage, E.H.9    Folkman, J.10
  • 193
    • 0142215651 scopus 로고    scopus 로고
    • Sodium butyrate inhibits angiogenesis of human intestinal microvascular endothelial cells through COX-2 inhibition
    • Ogawa, H., P. Rafiee, P. J. Fisher, N. A. Johnson, M. F. Otterson and D. G. Binion (2003). “Sodium butyrate inhibits angiogenesis of human intestinal microvascular endothelial cells through COX-2 inhibition.” FEBS Lett 554(1-2): 88-94.
    • (2003) FEBS Lett , vol.554 , Issue.1-2 , pp. 88-94
    • Ogawa, H.1    Rafiee, P.2    Fisher, P.J.3    Johnson, N.A.4    Otterson, M.F.5    Binion, D.G.6
  • 194
    • 0037207863 scopus 로고    scopus 로고
    • Expression of the leukotriene D4 receptor CysLT1, COX-2, and other cell survival factors in colorectal adenocarcinomas
    • Ohd, J. F., C. K. Nielsen, J. Campbell, G. Landberg, H. Lofberg and A. Sjolander (2003). “Expression of the leukotriene D4 receptor CysLT1, COX-2, and other cell survival factors in colorectal adenocarcinomas.” Gastroenterology 124(1): 57-70.
    • (2003) Gastroenterology , vol.124 , Issue.1 , pp. 57-70
    • Ohd, J.F.1    Nielsen, C.K.2    Campbell, J.3    Landberg, G.4    Lofberg, H.5    Sjolander, A.6
  • 195
    • 17344367171 scopus 로고    scopus 로고
    • Upregulation of prostacyclin synthesis-related gene expression by shear stress in vascular endothelial cells
    • Okahara, K., B. Sun and J. Kambayashi (1998). “Upregulation of prostacyclin synthesis-related gene expression by shear stress in vascular endothelial cells.” Arterioscler Thromb Vasc Biol 18(12): 1922-1926.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , Issue.12 , pp. 1922-1926
    • Okahara, K.1    Sun, B.2    Kambayashi, J.3
  • 196
    • 0042916422 scopus 로고    scopus 로고
    • Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors
    • Pai, R., T. Nakamura, W. S. Moon and A. S. Tarnawski (2003). “Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors.” Faseb J 17(12): 1640-1647.
    • (2003) Faseb J , vol.17 , Issue.12 , pp. 1640-1647
    • Pai, R.1    Nakamura, T.2    Moon, W.S.3    Tarnawski, A.S.4
  • 197
  • 199
    • 2342475704 scopus 로고    scopus 로고
    • Zebrafish: A preclinical model for drug screening
    • Parng, C., W. L. Seng, C. Semino and P. McGrath (2002). “Zebrafish: a preclinical model for drug screening.” Assay Drug Dev Technol 1(1 Pt 1): 41-48.
    • (2002) Assay Drug Dev Technol , vol.1 , Issue.1 , pp. 41-48
    • Parng, C.1    Seng, W.L.2    Semino, C.3    McGrath, P.4
  • 202
    • 1842478183 scopus 로고    scopus 로고
    • Hypoxic regulation of angiopoietin-2 expression in endothelial cells
    • Pichiule, P., J. C. Chavez and J. C. LaManna (2004). “Hypoxic regulation of angiopoietin-2 expression in endothelial cells.” J Biol Chem 279(13): 12171-12180.
    • (2004) J Biol Chem , vol.279 , Issue.13 , pp. 12171-12180
    • Pichiule, P.1    Chavez, J.C.2    LaManna, J.C.3
  • 203
    • 0036570319 scopus 로고    scopus 로고
    • Mechanisms controlling cell cycle arrest and induction of apoptosis after 12-lipoxygenase inhibition in prostate cancer cells
    • Pidgeon, G. P., M. Kandouz, A. Meram and K. V. Honn (2002). “Mechanisms controlling cell cycle arrest and induction of apoptosis after 12-lipoxygenase inhibition in prostate cancer cells.” Cancer Res 62(9): 2721-2727.
    • (2002) Cancer Res , vol.62 , Issue.9 , pp. 2721-2727
    • Pidgeon, G.P.1    Kandouz, M.2    Meram, A.3    Honn, K.V.4
  • 204
    • 7544248222 scopus 로고    scopus 로고
    • Intravascular thrombosis after hypoxia-induced pulmonary hypertension: Regulation by cyclooxygenase-2
    • Pidgeon, G. P., R. Tamosiuniene, G. Chen, I. Leonard, O. Belton, A. Bradford and D. J. Fitzgerald (2004). “Intravascular thrombosis after hypoxia-induced pulmonary hypertension: regulation by cyclooxygenase-2.” Circulation 110(17): 2701-2707.
    • (2004) Circulation , vol.110 , Issue.17 , pp. 2701-2707
    • Pidgeon, G.P.1    Tamosiuniene, R.2    Chen, G.3    Leonard, I.4    Belton, O.5    Bradford, A.6    Fitzgerald, D.J.7
  • 205
    • 1542328876 scopus 로고    scopus 로고
    • Comparative analysis of the in vivo angiogenic properties of stable prostacyclin analogs: A possible role for peroxisome proliferator-activated receptors
    • Pola, R., E. Gaetani, A. Flex, T. R. Aprahamian, M. Bosch-Marce, D. W. Losordo, R. C. Smith and P. Pola (2004). “Comparative analysis of the in vivo angiogenic properties of stable prostacyclin analogs: a possible role for peroxisome proliferator-activated receptors.” J Mol Cell Cardiol 36(3): 363-370.
    • (2004) J Mol Cell Cardiol , vol.36 , Issue.3 , pp. 363-370
    • Pola, R.1    Gaetani, E.2    Flex, A.3    Aprahamian, T.R.4    Bosch-Marce, M.5    Losordo, D.W.6    Smith, R.C.7    Pola, P.8
  • 207
    • 0036142958 scopus 로고    scopus 로고
    • Gene transfer of thromboxane A(2) synthase and prostaglandin I(2) synthase antithetically altered tumor angiogenesis and tumor growth
    • Pradono, P., R. Tazawa, M. Maemondo, M. Tanaka, K. Usui, Y. Saijo, K. Hagiwara and T. Nukiwa (2002). “Gene transfer of thromboxane A(2) synthase and prostaglandin I(2) synthase antithetically altered tumor angiogenesis and tumor growth.” Cancer Res 62(1): 63-66.
    • (2002) Cancer Res , vol.62 , Issue.1 , pp. 63-66
    • Pradono, P.1    Tazawa, R.2    Maemondo, M.3    Tanaka, M.4    Usui, K.5    Saijo, Y.6    Hagiwara, K.7    Nukiwa, T.8
  • 208
    • 2942574455 scopus 로고    scopus 로고
    • Invasive and angiogenic phenotype of MCF-7 human breast tumor cells expressing human cyclooxygenase-2
    • Prosperi, J. R., S. R. Mallery, K. A. Kigerl, A. A. Erfurt and F. M. Robertson (2004). “Invasive and angiogenic phenotype of MCF-7 human breast tumor cells expressing human cyclooxygenase-2.” Prostaglandins Other Lipid Mediat 73(3-4): 249-264.
    • (2004) Prostaglandins Other Lipid Mediat , vol.73 , Issue.3-4 , pp. 249-264
    • Prosperi, J.R.1    Mallery, S.R.2    Kigerl, K.A.3    Erfurt, A.A.4    Robertson, F.M.5
  • 209
    • 0032004520 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor expression by cAMP in rat aortic smooth muscle cells
    • Pueyo, M. E., Y. Chen, G. D’Angelo and J. B. Michel (1998). “Regulation of vascular endothelial growth factor expression by cAMP in rat aortic smooth muscle cells.” Exp Cell Res 238(2): 354-358.
    • (1998) Exp Cell Res , vol.238 , Issue.2 , pp. 354-358
    • Pueyo, M.E.1    Chen, Y.2    D’Angelo, G.3    Michel, J.B.4
  • 210
    • 34547121441 scopus 로고    scopus 로고
    • Prostaglandin F(2alpha) stimulates motility and invasion in colorectal tumor cells
    • Qualtrough, D., A. Kaidi, S. Chell, H. N. Jabbour, A. C. Williams and C. Paraskeva (2007). “Prostaglandin F(2alpha) stimulates motility and invasion in colorectal tumor cells.” Int J Cancer 121(4): 734-740.
    • (2007) Int J Cancer , vol.121 , Issue.4 , pp. 734-740
    • Qualtrough, D.1    Kaidi, A.2    Chell, S.3    Jabbour, H.N.4    Williams, A.C.5    Paraskeva, C.6
  • 211
    • 0034743583 scopus 로고    scopus 로고
    • Ectopic alphaIIbbeta3 integrin signaling involves 12-lipoxygenase- and PKCmediated serine phosphorylation events in melanoma cells
    • Raso, E., J. Tovari, K. Toth, S. Paku, M. Trikha, K. V. Honn and J. Timar (2001). “Ectopic alphaIIbbeta3 integrin signaling involves 12-lipoxygenase- and PKCmediated serine phosphorylation events in melanoma cells.” Thromb Haemost 85(6): 1037-1042.
    • (2001) Thromb Haemost , vol.85 , Issue.6 , pp. 1037-1042
    • Raso, E.1    Tovari, J.2    Toth, K.3    Paku, S.4    Trikha, M.5    Honn, K.V.6    Timar, J.7
  • 216
    • 0035659473 scopus 로고    scopus 로고
    • Intracellular signaling pathway of FGF-2-modulated corneal endothelial cell migration during wound healing in vitro
    • Rieck, P. W., S. Cholidis and C. Hartmann (2001). “Intracellular signaling pathway of FGF-2-modulated corneal endothelial cell migration during wound healing in vitro.” Exp Eye Res 73(5): 639-650.
    • (2001) Exp Eye Res , vol.73 , Issue.5 , pp. 639-650
    • Rieck, P.W.1    Cholidis, S.2    Hartmann, C.3
  • 217
    • 0032403140 scopus 로고    scopus 로고
    • Prevention of NNK-induced lung tumorigenesis in A/J mice by acetylsalicylic acid and NS-398
    • Rioux, N. and A. Castonguay (1998). “Prevention of NNK-induced lung tumorigenesis in A/J mice by acetylsalicylic acid and NS-398.” Cancer Res 58(23): 5354-5360.
    • (1998) Cancer Res , vol.58 , Issue.23 , pp. 5354-5360
    • Rioux, N.1    Castonguay, A.2
  • 219
    • 0035162355 scopus 로고    scopus 로고
    • 5-lipoxygenase regulates malignant mesothelial cell survival: Involvement of vascular endothelial growth factor
    • Romano, M., A. Catalano, M. Nutini, E. D’Urbano, C. Crescenzi, J. Claria, R. Libner, G. Davi and A. Procopio (2001). "5-lipoxygenase regulates malignant mesothelial cell survival: involvement of vascular endothelial growth factor.” Faseb J 15(13): 2326-2336.
    • (2001) Faseb J , vol.15 , Issue.13 , pp. 2326-2336
    • Romano, M.1    Catalano, A.2    Nutini, M.3    D’Urbano, E.4    Crescenzi, C.5    Claria, J.6    Libner, R.7    Davi, G.8    Procopio, A.9
  • 220
    • 0035882534 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors retard murine mammary tumor progression by reducing tumor cell migration, invasiveness and angiogenesis
    • Rozic, J. G., C. Chakraborty and P. K. Lala (2001). “Cyclooxygenase inhibitors retard murine mammary tumor progression by reducing tumor cell migration, invasiveness and angiogenesis.” Int J Cancer 93(4): 497-506.
    • (2001) Int J Cancer , vol.93 , Issue.4 , pp. 497-506
    • Rozic, J.G.1    Chakraborty, C.2    Lala, P.K.3
  • 222
    • 0141679091 scopus 로고    scopus 로고
    • Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells
    • Salcedo, R., X. Zhang, H. A. Young, N. Michael, K. Wasserman, W. H. Ma, M. Martins-Green, W. J. Murphy and J. J. Oppenheim (2003). “Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells.” Blood 102(6): 1966-1977.
    • (2003) Blood , vol.102 , Issue.6 , pp. 1966-1977
    • Salcedo, R.1    Zhang, X.2    Young, H.A.3    Michael, N.4    Wasserman, K.5    Ma, W.H.6    Martins-Green, M.7    Murphy, W.J.8    Oppenheim, J.J.9
  • 223
    • 24744457573 scopus 로고    scopus 로고
    • A novel angiogenic role for prostaglandin F2alpha-FP receptor interaction in human endometrial adenocarcinomas
    • Sales, K. J., T. List, S. C. Boddy, A. R. Williams, R. A. Anderson, Z. Naor and H. N. Jabbour (2005). “A novel angiogenic role for prostaglandin F2alpha-FP receptor interaction in human endometrial adenocarcinomas.” Cancer Res 65(17): 7707-7716.
    • (2005) Cancer Res , vol.65 , Issue.17 , pp. 7707-7716
    • Sales, K.J.1    List, T.2    Boddy, S.C.3    Williams, A.R.4    Anderson, R.A.5    Naor, Z.6    Jabbour, H.N.7
  • 224
    • 0000619338 scopus 로고
    • A new method for the microscopic study of living growing tissues by the introduction of a transparent chamber in the rabbits ear
    • Sandison, J. C. (1924). “A new method for the microscopic study of living growing tissues by the introduction of a transparent chamber in the rabbits ear. " Anat. Rec. 28: 281-287.
    • (1924) Anat. Rec. , vol.28 , pp. 281-287
    • Sandison, J.C.1
  • 225
    • 0030801081 scopus 로고    scopus 로고
    • Inhibition of metastasis by cicaprost in rats with established SMT2A mammary carcinoma growth
    • Schirner, M. and M. R. Schneider (1997). “Inhibition of metastasis by cicaprost in rats with established SMT2A mammary carcinoma growth.” Cancer Detect Prev 21(1): 44-50.
    • (1997) Cancer Detect Prev , vol.21 , Issue.1 , pp. 44-50
    • Schirner, M.1    Schneider, M.R.2
  • 226
    • 0031034814 scopus 로고    scopus 로고
    • Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells
    • Schmedtje, J. F., Jr., Y. S. Ji, W. L. Liu, R. N. DuBois and M. S. Runge (1997). “Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells.” J Biol Chem 272(1): 601-608.
    • (1997) J Biol Chem , vol.272 , Issue.1 , pp. 601-608
    • Schmedtje, J.F.1    Ji, Y.S.2    Liu, W.L.3    DuBois, R.N.4    Runge, M.S.5
  • 227
    • 83855165727 scopus 로고    scopus 로고
    • Cyclooxygenases and lipoxygenases in cancer
    • Schneider, C. and A. Pozzi (2011). “Cyclooxygenases and lipoxygenases in cancer.” Cancer Metastasis Rev 30(3-4): 277-294.
    • (2011) Cancer Metastasis Rev , vol.30 , Issue.3-4 , pp. 277-294
    • Schneider, C.1    Pozzi, A.2
  • 229
    • 0036239135 scopus 로고    scopus 로고
    • Persistent accumulation of cyclooxygenase-1-expressing microglial cells and macrophages and transient upregulation by endothelium in human brain injury
    • Schwab, J. M., R. Beschorner, R. Meyermann, F. Gozalan and H. J. Schluesener (2002). “Persistent accumulation of cyclooxygenase-1-expressing microglial cells and macrophages and transient upregulation by endothelium in human brain injury.” J Neurosurg 96(5): 892-899.
    • (2002) J Neurosurg , vol.96 , Issue.5 , pp. 892-899
    • Schwab, J.M.1    Beschorner, R.2    Meyermann, R.3    Gozalan, F.4    Schluesener, H.J.5
  • 231
    • 67449098974 scopus 로고    scopus 로고
    • Inhibitory effect of sulindac on DMBA-induced hamster cheek pouch carcinogenesis and its derived cell line
    • Segawa, E., S. Hashitani, Y. Toyohara, H. Kishimoto, K. Noguchi, K. Takaoka and M. Urade (2009). “Inhibitory effect of sulindac on DMBA-induced hamster cheek pouch carcinogenesis and its derived cell line.” Oncol Rep 21(4): 869-874.
    • (2009) Oncol Rep , vol.21 , Issue.4 , pp. 869-874
    • Segawa, E.1    Hashitani, S.2    Toyohara, Y.3    Kishimoto, H.4    Noguchi, K.5    Takaoka, K.6    Urade, M.7
  • 232
    • 0037081194 scopus 로고    scopus 로고
    • Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps
    • Seno, H., M. Oshima, T. O. Ishikawa, H. Oshima, K. Takaku, T. Chiba, S. Narumiya and M. M. Taketo (2002). “Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps.” Cancer Res 62(2): 506-511.
    • (2002) Cancer Res , vol.62 , Issue.2 , pp. 506-511
    • Seno, H.1    Oshima, M.2    Ishikawa, T.O.3    Oshima, H.4    Takaku, K.5    Chiba, T.6    Narumiya, S.7    Taketo, M.M.8
  • 233
    • 73449139739 scopus 로고    scopus 로고
    • Participation of 5-lipoxygenase-derived LTB(4) in 4-hydroxynonenalenhanced MMP-2 production in vascular smooth muscle cells
    • Seo, K. W., S. J. Lee, C. E. Kim, M. R. Yun, H. M. Park, J. W. Yun, S. S. Bae and C. D. Kim (2010). “Participation of 5-lipoxygenase-derived LTB(4) in 4-hydroxynonenalenhanced MMP-2 production in vascular smooth muscle cells.” Atherosclerosis 208(1): 56-61.
    • (2010) Atherosclerosis , vol.208 , Issue.1 , pp. 56-61
    • Seo, K.W.1    Lee, S.J.2    Kim, C.E.3    Yun, M.R.4    Park, H.M.5    Yun, J.W.6    Bae, S.S.7    Kim, C.D.8
  • 234
    • 0032984374 scopus 로고    scopus 로고
    • 15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma
    • Shappell, S. B., W. E. Boeglin, S. J. Olson, S. Kasper and A. R. Brash (1999). "15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma.” Am J Pathol 155(1): 235-245.
    • (1999) Am J Pathol , vol.155 , Issue.1 , pp. 235-245
    • Shappell, S.B.1    Boeglin, W.E.2    Olson, S.J.3    Kasper, S.4    Brash, A.R.5
  • 235
    • 0030785484 scopus 로고    scopus 로고
    • Expression of functional luteinizing hormone (LH) receptor and its messenger ribonucleic acid in bovine uterine veins: LH induction of cyclooxygenase and augmentation of prostaglandin production in bovine uterine veins
    • Shemesh, M., M. Gurevich, D. Mizrachi, L. Dombrovski, Y. Stram, M. J. Fields and L. S. Shore (1997). “Expression of functional luteinizing hormone (LH) receptor and its messenger ribonucleic acid in bovine uterine veins: LH induction of cyclooxygenase and augmentation of prostaglandin production in bovine uterine veins.” Endocrinology 138(11): 4844-4851.
    • (1997) Endocrinology , vol.138 , Issue.11 , pp. 4844-4851
    • Shemesh, M.1    Gurevich, M.2    Mizrachi, D.3    Dombrovski, L.4    Stram, Y.5    Fields, M.J.6    Shore, L.S.7
  • 236
    • 77951883817 scopus 로고    scopus 로고
    • Activation of 5-lipoxygenase is required for nicotine mediated epithelial-mesenchymal transition and tumor cell growth
    • Shin, V. Y., H. C. Jin, E. K. Ng, J. J. Sung, K. M. Chu and C. H. Cho (2010). “Activation of 5-lipoxygenase is required for nicotine mediated epithelial-mesenchymal transition and tumor cell growth.” Cancer Lett 292(2): 237-245.
    • (2010) Cancer Lett , vol.292 , Issue.2 , pp. 237-245
    • Shin, V.Y.1    Jin, H.C.2    Ng, E.K.3    Sung, J.J.4    Chu, K.M.5    Cho, C.H.6
  • 237
    • 0035417925 scopus 로고    scopus 로고
    • Lipoxygenase modulation to reverse carcinogenesis
    • Shureiqi, I. and S. M. Lippman (2001). “Lipoxygenase modulation to reverse carcinogenesis.” Cancer Res 61(17): 6307-6312.
    • (2001) Cancer Res , vol.61 , Issue.17 , pp. 6307-6312
    • Shureiqi, I.1    Lippman, S.M.2
  • 240
    • 81555214613 scopus 로고    scopus 로고
    • 12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation
    • Singh, N. K., V. Kundumani-Sridharan and G. N. Rao (2011). "12/15-Lipoxygenase gene knockout severely impairs ischemia-induced angiogenesis due to lack of Rac1 farnesylation.” Blood 118(20): 5701-5712.
    • (2011) Blood , vol.118 , Issue.20 , pp. 5701-5712
    • Singh, N.K.1    Kundumani-Sridharan, V.2    Rao, G.N.3
  • 243
    • 0034796261 scopus 로고    scopus 로고
    • Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice
    • Sonoshita, M., K. Takaku, N. Sasaki, Y. Sugimoto, F. Ushikubi, S. Narumiya, M. Oshima and M. M. Taketo (2001). “Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice.” Nat Med 7(9): 1048-1051.
    • (2001) Nat Med , vol.7 , Issue.9 , pp. 1048-1051
    • Sonoshita, M.1    Takaku, K.2    Sasaki, N.3    Sugimoto, Y.4    Ushikubi, F.5    Narumiya, S.6    Oshima, M.7    Taketo, M.M.8
  • 244
    • 0022474347 scopus 로고
    • Survival of mice with NC carcinoma is unchanged by drugs that are thought to inhibit thromboxane synthesis or increase prostacyclin formation
    • Stamford, I. F., P. B. Melhuish, M. A. Carroll, C. J. Corrigan, S. Patel and A. Bennett (1986). “Survival of mice with NC carcinoma is unchanged by drugs that are thought to inhibit thromboxane synthesis or increase prostacyclin formation.” Br J Cancer 54(2): 257-263.
    • (1986) Br J Cancer , vol.54 , Issue.2 , pp. 257-263
    • Stamford, I.F.1    Melhuish, P.B.2    Carroll, M.A.3    Corrigan, C.J.4    Patel, S.5    Bennett, A.6
  • 245
    • 36849006838 scopus 로고    scopus 로고
    • Highresolution imaging of the dynamic tumor cell vascular interface in transparent zebrafish
    • Stoletov, K., V. Montel, R. D. Lester, S. L. Gonias and R. Klemke (2007). “Highresolution imaging of the dynamic tumor cell vascular interface in transparent zebrafish.” Proc Natl Acad Sci USA 104(44): 17406-17411.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.44 , pp. 17406-17411
    • Stoletov, K.1    Montel, V.2    Lester, R.D.3    Gonias, S.L.4    Klemke, R.5
  • 248
    • 0032833826 scopus 로고    scopus 로고
    • Activation of matrix metalloproteinase-2 in human breast cancer cells overexpressing cyclooxygenase-1 or -2
    • Takahashi, Y., F. Kawahara, M. Noguchi, K. Miwa, H. Sato, M. Seiki, H. Inoue, T. Tanabe and T. Yoshimoto (1999). “Activation of matrix metalloproteinase-2 in human breast cancer cells overexpressing cyclooxygenase-1 or -2.” FEBS Lett 460(1): 145-148.
    • (1999) FEBS Lett , vol.460 , Issue.1 , pp. 145-148
    • Takahashi, Y.1    Kawahara, F.2    Noguchi, M.3    Miwa, K.4    Sato, H.5    Seiki, M.6    Inoue, H.7    Tanabe, T.8    Yoshimoto, T.9
  • 249
    • 0036325931 scopus 로고    scopus 로고
    • Vascular endothelial growth factor up-regulates cyclooxygenase-2 expression in human endothelial cells
    • Tamura, M., S. Sebastian, B. Gurates, S. Yang, Z. Fang and S. E. Bulun (2002). “Vascular endothelial growth factor up-regulates cyclooxygenase-2 expression in human endothelial cells.” J Clin Endocrinol Metab 87(7): 3504-3507.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.7 , pp. 3504-3507
    • Tamura, M.1    Sebastian, S.2    Gurates, B.3    Yang, S.4    Fang, Z.5    Bulun, S.E.6
  • 250
    • 33845330927 scopus 로고    scopus 로고
    • 15-lipoxygenase 2 (15-LOX2) is a functional tumor suppressor that regulates human prostate epithelial cell differentiation, senescence, and growth (size)
    • Tang, D. G., B. Bhatia, S. Tang and R. Schneider-Broussard (2007). "15-lipoxygenase 2 (15-LOX2) is a functional tumor suppressor that regulates human prostate epithelial cell differentiation, senescence, and growth (size).” Prostaglandins Other Lipid Mediat 82(1-4): 135-146.
    • (2007) Prostaglandins Other Lipid Mediat , vol.82 , Issue.1-4 , pp. 135-146
    • Tang, D.G.1    Bhatia, B.2    Tang, S.3    Schneider-Broussard, R.4
  • 251
    • 0027269576 scopus 로고
    • 12(S)-HETE promotes tumor-cell adhesion by increasing surface expression of alpha V beta 3 integrins on endothelial cells
    • Tang, D. G., I. M. Grossi, Y. Q. Chen, C. A. Diglio and K. V. Honn (1993). "12(S)-HETE promotes tumor-cell adhesion by increasing surface expression of alpha V beta 3 integrins on endothelial cells.” Int J Cancer 54(1): 102-111.
    • (1993) Int J Cancer , vol.54 , Issue.1 , pp. 102-111
    • Tang, D.G.1    Grossi, I.M.2    Chen, Y.Q.3    Diglio, C.A.4    Honn, K.V.5
  • 252
    • 0034724377 scopus 로고    scopus 로고
    • Identification of 12-lipoxygenase interaction with cellular proteins by yeast two-hybrid screening
    • Tang, K., R. L. Finley, Jr., D. Nie and K. V. Honn (2000). “Identification of 12-lipoxygenase interaction with cellular proteins by yeast two-hybrid screening.” Biochemistry 39(12): 3185-3191.
    • (2000) Biochemistry , vol.39 , Issue.12 , pp. 3185-3191
    • Tang, K.1    Finley, R.L.2    Nie, D.3    Honn, K.V.4
  • 253
    • 61449149630 scopus 로고    scopus 로고
    • Downregulation of vascular endothelial growth factor and induction of tumor dormancy by 15-lipoxygenase-2 in prostate cancer
    • Tang, Y., M. T. Wang, Y. Chen, D. Yang, M. Che, K. V. Honn, G. D. Akers, S. R. Johnson and D. Nie (2009). “Downregulation of vascular endothelial growth factor and induction of tumor dormancy by 15-lipoxygenase-2 in prostate cancer.” Int J Cancer 124(7): 1545-1551.
    • (2009) Int J Cancer , vol.124 , Issue.7 , pp. 1545-1551
    • Tang, Y.1    Wang, M.T.2    Chen, Y.3    Yang, D.4    Che, M.5    Honn, K.V.6    Akers, G.D.7    Johnson, S.R.8    Nie, D.9
  • 255
    • 0037158892 scopus 로고    scopus 로고
    • Breast cancer cell-derived EMMPRIN stimulates fibroblast MMP2 release through a phospholipase A(2) and 5-lipoxygenase catalyzed pathway
    • Taylor, P. M., R. J. Woodfield, M. N. Hodgkin, T. R. Pettitt, A. Martin, D. J. Kerr and M. J. Wakelam (2002). “Breast cancer cell-derived EMMPRIN stimulates fibroblast MMP2 release through a phospholipase A(2) and 5-lipoxygenase catalyzed pathway.” Oncogene 21(37): 5765-5772.
    • (2002) Oncogene , vol.21 , Issue.37 , pp. 5765-5772
    • Taylor, P.M.1    Woodfield, R.J.2    Hodgkin, M.N.3    Pettitt, T.R.4    Martin, A.5    Kerr, D.J.6    Wakelam, M.J.7
  • 256
    • 0026486664 scopus 로고
    • Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease
    • Teicher, B. A., E. A. Sotomayor and Z. D. Huang (1992). “Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease.” Cancer Res 52(23): 6702-6704.
    • (1992) Cancer Res , vol.52 , Issue.23 , pp. 6702-6704
    • Teicher, B.A.1    Sotomayor, E.A.2    Huang, Z.D.3
  • 257
    • 77955762194 scopus 로고    scopus 로고
    • Inhibition of hypoxia inducible factor-1alpha by dihydroxyphenylethanol, a product from olive oil, blocks microsomal prostaglandin-E synthase-1/vascular endothelial growth factor expression and reduces tumor angiogenesis
    • Terzuoli, E., S. Donnini, A. Giachetti, M. A. Iniguez, M. Fresno, G. Melillo and M. Ziche (2010). “Inhibition of hypoxia inducible factor-1alpha by dihydroxyphenylethanol, a product from olive oil, blocks microsomal prostaglandin-E synthase-1/vascular endothelial growth factor expression and reduces tumor angiogenesis.” Clin Cancer Res 16(16): 4207-4216.
    • (2010) Clin Cancer Res , vol.16 , Issue.16 , pp. 4207-4216
    • Terzuoli, E.1    Donnini, S.2    Giachetti, A.3    Iniguez, M.A.4    Fresno, M.5    Melillo, G.6    Ziche, M.7
  • 258
    • 0037138743 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs as anticancer agents: Mechanistic, pharmacologic, and clinical issues
    • Thun, M. J., S. J. Henley and C. Patrono (2002). “Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues.” J Natl Cancer Inst 94(4): 252-266.
    • (2002) J Natl Cancer Inst , vol.94 , Issue.4 , pp. 252-266
    • Thun, M.J.1    Henley, S.J.2    Patrono, C.3
  • 259
    • 26444601121 scopus 로고    scopus 로고
    • Plateletmimicry of cancer cells: Epiphenomenon with clinical significance
    • Timar, J., J. Tovari, E. Raso, L. Meszaros, B. Bereczky and K. Lapis (2005). “Plateletmimicry of cancer cells: epiphenomenon with clinical significance.” Oncology 69(3): 185-201.
    • (2005) Oncology , vol.69 , Issue.3 , pp. 185-201
    • Timar, J.1    Tovari, J.2    Raso, E.3    Meszaros, L.4    Bereczky, B.5    Lapis, K.6
  • 260
    • 79952279276 scopus 로고    scopus 로고
    • Antiangiogenic effects of resveratrol mediated by decreased VEGF and increased TSP1 expression in melanoma-endothelial cell co-culture
    • Trapp, V., B. Parmakhtiar, V. Papazian, L. Willmott and J. P. Fruehauf (2010). “Antiangiogenic effects of resveratrol mediated by decreased VEGF and increased TSP1 expression in melanoma-endothelial cell co-culture.” Angiogenesis 13(4): 305-315.
    • (2010) Angiogenesis , vol.13 , Issue.4 , pp. 305-315
    • Trapp, V.1    Parmakhtiar, B.2    Papazian, V.3    Willmott, L.4    Fruehauf, J.P.5
  • 261
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • Tsujii, M., S. Kawano, S. Tsuji, H. Sawaoka, M. Hori and R. N. DuBois (1998). “Cyclooxygenase regulates angiogenesis induced by colon cancer cells.” Cell 93(5): 705-716.
    • (1998) Cell , vol.93 , Issue.5 , pp. 705-716
    • Tsujii, M.1    Kawano, S.2    Tsuji, S.3    Sawaoka, H.4    Hori, M.5    DuBois, R.N.6
  • 262
    • 79961040974 scopus 로고    scopus 로고
    • Interaction of the human prostacyclin receptor with the PDZ adapter protein PDZK1: Role in endothelial cell migration and angiogenesis
    • Turner, E. C., E. P. Mulvaney, H. M. Reid and B. T. Kinsella (2011). “Interaction of the human prostacyclin receptor with the PDZ adapter protein PDZK1: role in endothelial cell migration and angiogenesis.” Mol Biol Cell 22(15): 2664-2679.
    • (2011) Mol Biol Cell , vol.22 , Issue.15 , pp. 2664-2679
    • Turner, E.C.1    Mulvaney, E.P.2    Reid, H.M.3    Kinsella, B.T.4
  • 263
    • 0032563812 scopus 로고    scopus 로고
    • A function for lipoxygenase in programmed organelle degradation
    • van Leyen, K., R. M. Duvoisin, H. Engelhardt and M. Wiedmann (1998). “A function for lipoxygenase in programmed organelle degradation.” Nature 395(6700): 392-395.
    • (1998) Nature , vol.395 , Issue.6700 , pp. 392-395
    • van Leyen, K.1    Duvoisin, R.M.2    Engelhardt, H.3    Wiedmann, M.4
  • 264
    • 76149113599 scopus 로고    scopus 로고
    • Antiangogenic effect of selected phytochemicals
    • Varinska, L., L. Mirossay, G. Mojzisova and J. Mojzis (2010). “Antiangogenic effect of selected phytochemicals.” Pharmazie 65(1): 57-63.
    • (2010) Pharmazie , vol.65 , Issue.1 , pp. 57-63
    • Varinska, L.1    Mirossay, L.2    Mojzisova, G.3    Mojzis, J.4
  • 265
    • 74549130049 scopus 로고    scopus 로고
    • Intravitreal adenoviral 15-lipoxygenase-1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes
    • Viita, H., K. Kinnunen, E. Eriksson, J. Lahteenvuo, M. Babu, G. Kalesnykas, T. Heikura, S. Laidinen, T. Takalo and S. Yla-Herttuala (2009). “Intravitreal adenoviral 15-lipoxygenase-1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes.” Hum Gene Ther 20(12): 1679-1686.
    • (2009) Hum Gene Ther , vol.20 , Issue.12 , pp. 1679-1686
    • Viita, H.1    Kinnunen, K.2    Eriksson, E.3    Lahteenvuo, J.4    Babu, M.5    Kalesnykas, G.6    Heikura, T.7    Laidinen, S.8    Takalo, T.9    Yla-Herttuala, S.10
  • 266
    • 41149111018 scopus 로고    scopus 로고
    • 15-lipoxygenase-1 prevents vascular endothelial growth factor A- and placental growth factor-induced angiogenic effects in rabbit skeletal muscles via reduction in growth factor mRNA levels, NO bioactivity, and downregulation of VEGF receptor 2 expression
    • Viita, H., J. Markkanen, E. Eriksson, M. Nurminen, K. Kinnunen, M. Babu, T. Heikura, S. Turpeinen, S. Laidinen, T. Takalo and S. Yla-Herttuala (2008). "15-lipoxygenase-1 prevents vascular endothelial growth factor A- and placental growth factor-induced angiogenic effects in rabbit skeletal muscles via reduction in growth factor mRNA levels, NO bioactivity, and downregulation of VEGF receptor 2 expression.” Circ Res 102(2): 177-184.
    • (2008) Circ Res , vol.102 , Issue.2 , pp. 177-184
    • Viita, H.1    Markkanen, J.2    Eriksson, E.3    Nurminen, M.4    Kinnunen, K.5    Babu, M.6    Heikura, T.7    Turpeinen, S.8    Laidinen, S.9    Takalo, T.10    Yla-Herttuala, S.11
  • 267
    • 20444453338 scopus 로고    scopus 로고
    • Coexpression of cyclooxygenases (COX-1, COX-2) and vascular endothelial growth factors (VEGF-A, VEGF-C) in esophageal adenocarcinoma
    • von Rahden, B. H., H. J. Stein, F. Puhringer, I. Koch, R. Langer, G. Piontek, J. R. Siewert, H. Hofler and M. Sarbia (2005). “Coexpression of cyclooxygenases (COX-1, COX-2) and vascular endothelial growth factors (VEGF-A, VEGF-C) in esophageal adenocarcinoma.” Cancer Res 65(12): 5038-5044.
    • (2005) Cancer Res , vol.65 , Issue.12 , pp. 5038-5044
    • von Rahden, B.H.1    Stein, H.J.2    Puhringer, F.3    Koch, I.4    Langer, R.5    Piontek, G.6    Siewert, J.R.7    Hofler, H.8    Sarbia, M.9
  • 268
    • 38449095968 scopus 로고    scopus 로고
    • Measurement of eicosanoids in cancer tissues
    • Wang, D. and R. N. DuBois (2007). “Measurement of eicosanoids in cancer tissues.” Methods Enzymol 433: 27-50.
    • (2007) Methods Enzymol , vol.433 , pp. 27-50
    • Wang, D.1    DuBois, R.N.2
  • 269
    • 77649179672 scopus 로고    scopus 로고
    • Eicosanoids and cancer
    • Wang, D. and R. N. DuBois (2010). “Eicosanoids and cancer.” Nat Rev Cancer 10(3): 181-193.
    • (2010) Nat Rev Cancer , vol.10 , Issue.3 , pp. 181-193
    • Wang, D.1    DuBois, R.N.2
  • 271
    • 42049088505 scopus 로고    scopus 로고
    • Celecoxib inhibits tumor growth and angiogenesis in an orthotopic implantation tumor model of human colon cancer
    • Wang, L., W. Chen, X. Xie, Y. He and X. Bai (2008). “Celecoxib inhibits tumor growth and angiogenesis in an orthotopic implantation tumor model of human colon cancer.” Exp Oncol 30(1): 42-51.
    • (2008) Exp Oncol , vol.30 , Issue.1 , pp. 42-51
    • Wang, L.1    Chen, W.2    Xie, X.3    He, Y.4    Bai, X.5
  • 272
    • 36148978529 scopus 로고    scopus 로고
    • Cyclooxygenases, prostanoids, and tumor progression
    • Wang, M. T., K. V. Honn and D. Nie (2007). “Cyclooxygenases, prostanoids, and tumor progression.” Cancer Metastasis Rev 26(3-4): 525-34.
    • (2007) Cancer Metastasis Rev , vol.26 , Issue.3-4 , pp. 525-534
    • Wang, M.T.1    Honn, K.V.2    Nie, D.3
  • 273
    • 84872453504 scopus 로고    scopus 로고
    • Combined histone deacetylase and cyclooxygenase inhibition achieves enhanced antiangiogenic effects in lung cancer cells
    • Nov 28 [Epub ahead of print]
    • Wang, X., G. Li, A. Wang, Z. Zhang, J. R. Merchan and B. Halmos (2011). “Combined histone deacetylase and cyclooxygenase inhibition achieves enhanced antiangiogenic effects in lung cancer cells.” Mol Carcinog Nov 28 [Epub ahead of print].
    • (2011) Mol Carcinog
    • Wang, X.1    Li, G.2    Wang, A.3    Zhang, Z.4    Merchan, J.R.5    Halmos, B.6
  • 275
    • 77953362012 scopus 로고    scopus 로고
    • Thromboxane receptor alpha mediates tumor growth and angiogenesis via induction of vascular endothelial growth factor expression in human lung cancer cells
    • Wei, J., W. Yan, X. Li, Y. Ding and H. H. Tai (2010). “Thromboxane receptor alpha mediates tumor growth and angiogenesis via induction of vascular endothelial growth factor expression in human lung cancer cells.” Lung Cancer 69(1): 26-32.
    • (2010) Lung Cancer , vol.69 , Issue.1 , pp. 26-32
    • Wei, J.1    Yan, W.2    Li, X.3    Ding, Y.4    Tai, H.H.5
  • 279
    • 0034089566 scopus 로고    scopus 로고
    • Host cyclooxygenase-2 modulates carcinoma growth
    • Williams, C. S., M. Tsujii, J. Reese, S. K. Dey and R. N. DuBois (2000). “Host cyclooxygenase-2 modulates carcinoma growth.” J Clin Invest 105(11): 1589-1594.
    • (2000) J Clin Invest , vol.105 , Issue.11 , pp. 1589-1594
    • Williams, C.S.1    Tsujii, M.2    Reese, J.3    Dey, S.K.4    DuBois, R.N.5
  • 280
    • 0033998334 scopus 로고    scopus 로고
    • The PPARs: From orphan receptors to drug discovery
    • Willson, T. M., P. J. Brown, D. D. Sternbach and B. R. Henke (2000). “The PPARs: from orphan receptors to drug discovery.” J Med Chem 43(4): 527-550.
    • (2000) J Med Chem , vol.43 , Issue.4 , pp. 527-550
    • Willson, T.M.1    Brown, P.J.2    Sternbach, D.D.3    Henke, B.R.4
  • 281
    • 84455193326 scopus 로고    scopus 로고
    • Baicalein mediates inhibition of migration and invasiveness of skin carcinoma through Ezrin in A431 cells
    • Wu, B., J. Li, D. Huang, W. Wang, Y. Chen, Y. Liao, X. Tang, H. Xie and F. Tang (2011). “Baicalein mediates inhibition of migration and invasiveness of skin carcinoma through Ezrin in A431 cells.” BMC Cancer 11: 527.
    • (2011) BMC Cancer , vol.11 , pp. 527
    • Wu, B.1    Li, J.2    Huang, D.3    Wang, W.4    Chen, Y.5    Liao, Y.6    Tang, X.7    Xie, H.8    Tang, F.9
  • 282
    • 30744476528 scopus 로고    scopus 로고
    • Involvement of COX-2 in VEGF-induced angiogenesis via P38 and JNK pathways in vascular endothelial cells
    • Wu, G., J. Luo, J. S. Rana, R. Laham, F. W. Sellke and J. Li (2006). “Involvement of COX-2 in VEGF-induced angiogenesis via P38 and JNK pathways in vascular endothelial cells.” Cardiovasc Res 69(2): 512-519.
    • (2006) Cardiovasc Res , vol.69 , Issue.2 , pp. 512-519
    • Wu, G.1    Luo, J.2    Rana, J.S.3    Laham, R.4    Sellke, F.W.5    Li, J.6
  • 283
    • 77953611147 scopus 로고    scopus 로고
    • Cyclooxygenase-2 in tumorigenesis of gastrointestinal cancers: An update on the molecular mechanisms
    • Wu, W. K., J. J. Sung, C. W. Lee, J. Yu and C. H. Cho (2010). “Cyclooxygenase-2 in tumorigenesis of gastrointestinal cancers: an update on the molecular mechanisms.” Cancer Lett 295(1): 7-16.
    • (2010) Cancer Lett , vol.295 , Issue.1 , pp. 7-16
    • Wu, W.K.1    Sung, J.J.2    Lee, C.W.3    Yu, J.4    Cho, C.H.5
  • 284
    • 33644527957 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors suppress angiogenesis and growth of gastric cancer xenografts
    • Wu, Y. L., S. L. Fu, Y. P. Zhang, M. M. Qiao and Y. Chen (2005). “Cyclooxygenase-2 inhibitors suppress angiogenesis and growth of gastric cancer xenografts.” Biomed Pharmacother 59 Suppl 2: S289-292.
    • (2005) Biomed Pharmacother 59 Suppl , vol.2 , pp. S289-S292
    • Wu, Y.L.1    Fu, S.L.2    Zhang, Y.P.3    Qiao, M.M.4    Chen, Y.5
  • 285
    • 0033605677 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo
    • Xin, X., S. Yang, J. Kowalski and M. E. Gerritsen (1999). “Peroxisome proliferatoractivated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo.” J Biol Chem 274(13): 9116-9121.
    • (1999) J Biol Chem , vol.274 , Issue.13 , pp. 9116-9121
    • Xin, X.1    Yang, S.2    Kowalski, J.3    Gerritsen, M.E.4
  • 286
    • 80053110423 scopus 로고    scopus 로고
    • 5-Lipoxygenase contributes to the progression of hepatocellular carcinoma
    • Xu, X. M., J. J. Deng, G. J. Yuan, F. Yang, H. T. Guo, M. Xiang, W. Ge and Y. G. Wu (2011). "5-Lipoxygenase contributes to the progression of hepatocellular carcinoma.” Mol Med Report 4(6): 1195-1200.
    • (2011) Mol Med Report , vol.4 , Issue.6 , pp. 1195-1200
    • Xu, X.M.1    Deng, J.J.2    Yuan, G.J.3    Yang, F.4    Guo, H.T.5    Xiang, M.6    Ge, W.7    Wu, Y.G.8
  • 287
    • 33750308463 scopus 로고    scopus 로고
    • Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism
    • Yang, L., Y. Huang, R. Porta, K. Yanagisawa, A. Gonzalez, E. Segi, D. H. Johnson, S. Narumiya and D. P. Carbone (2006). “Host and direct antitumor effects and profound reduction in tumor metastasis with selective EP4 receptor antagonism.” Cancer Res 66(19): 9665-9672.
    • (2006) Cancer Res , vol.66 , Issue.19 , pp. 9665-9672
    • Yang, L.1    Huang, Y.2    Porta, R.3    Yanagisawa, K.4    Gonzalez, A.5    Segi, E.6    Johnson, D.H.7    Narumiya, S.8    Carbone, D.P.9
  • 289
    • 14644420887 scopus 로고    scopus 로고
    • Effects of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer
    • Yao, M., W. Zhou, S. Sangha, A. Albert, A. J. Chang, T. C. Liu and M. M. Wolfe (2005). “Effects of nonselective cyclooxygenase inhibition with low-dose ibuprofen on tumor growth, angiogenesis, metastasis, and survival in a mouse model of colorectal cancer.” Clin Cancer Res 11(4): 1618-1628.
    • (2005) Clin Cancer Res , vol.11 , Issue.4 , pp. 1618-1628
    • Yao, M.1    Zhou, W.2    Sangha, S.3    Albert, A.4    Chang, A.J.5    Liu, T.C.6    Wolfe, M.M.7
  • 290
    • 17844390400 scopus 로고    scopus 로고
    • Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke
    • Ye, Y. N., W. K. Wu, V. Y. Shin, I. C. Bruce, B. C. Wong and C. H. Cho (2005). “Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke.” Carcinogenesis 26(4): 827-834.
    • (2005) Carcinogenesis , vol.26 , Issue.4 , pp. 827-834
    • Ye, Y.N.1    Wu, W.K.2    Shin, V.Y.3    Bruce, I.C.4    Wong, B.C.5    Cho, C.H.6
  • 291
    • 27744517051 scopus 로고    scopus 로고
    • A mechanistic study of colon cancer growth promoted by cigarette smoke extract
    • Ye, Y. N., W. K. Wu, V. Y. Shin and C. H. Cho (2005). “A mechanistic study of colon cancer growth promoted by cigarette smoke extract.” Eur J Pharmacol 519(1-2): 52-57.
    • (2005) Eur J Pharmacol , vol.519 , Issue.1-2 , pp. 52-57
    • Ye, Y.N.1    Wu, W.K.2    Shin, V.Y.3    Cho, C.H.4
  • 293
    • 79961167335 scopus 로고    scopus 로고
    • Combination of ciglitazone, a peroxisome proliferator-activated receptor gamma ligand, and cisplatin enhances the inhibition of growth of human ovarian cancers
    • Yokoyama, Y., B. Xin, T. Shigeto and H. Mizunuma (2011). “Combination of ciglitazone, a peroxisome proliferator-activated receptor gamma ligand, and cisplatin enhances the inhibition of growth of human ovarian cancers.” J Cancer Res Clin Oncol 137(8): 1219-1228.
    • (2011) J Cancer Res Clin Oncol , vol.137 , Issue.8 , pp. 1219-1228
    • Yokoyama, Y.1    Xin, B.2    Shigeto, T.3    Mizunuma, H.4
  • 294
    • 0032800431 scopus 로고    scopus 로고
    • Effect of shear stress and a stable prostaglandin I2 analogue on adhesive interactions of colon cancer cells and endothelial cells
    • Yoshida, N., T. Yoshikawa, S. Nakagawa, K. Sakamoto, Y. Nakamura, Y. Naito and M. Kondo (1999). “Effect of shear stress and a stable prostaglandin I2 analogue on adhesive interactions of colon cancer cells and endothelial cells.” Clin Exp Immunol 117(3): 430-434.
    • (1999) Clin Exp Immunol , vol.117 , Issue.3 , pp. 430-434
    • Yoshida, N.1    Yoshikawa, T.2    Nakagawa, S.3    Sakamoto, K.4    Nakamura, Y.5    Naito, Y.6    Kondo, M.7
  • 295
    • 0031826157 scopus 로고    scopus 로고
    • Inhibitory effects of prostaglandin D2 against the proliferation of human colon cancer cell lines and hepatic metastasis from colorectal cancer
    • Yoshida, T., S. Ohki, M. Kanazawa, H. Mizunuma, Y. Kikuchi, H. Satoh, Y. Andoh, A. Tsuchiya and R. Abe (1998). “Inhibitory effects of prostaglandin D2 against the proliferation of human colon cancer cell lines and hepatic metastasis from colorectal cancer.” Surg Today 28(7): 740-745.
    • (1998) Surg Today , vol.28 , Issue.7 , pp. 740-745
    • Yoshida, T.1    Ohki, S.2    Kanazawa, M.3    Mizunuma, H.4    Kikuchi, Y.5    Satoh, H.6    Andoh, Y.7    Tsuchiya, A.8    Abe, R.9
  • 296
    • 24744438296 scopus 로고    scopus 로고
    • Characterization of the prostaglandin biosynthetic pathway in non-small cell lung cancer: A comparison with small cell lung cancer and correlation with angiogenesis, angiogenic factors and metastases
    • Yoshimoto, A., K. Kasahara, A. Kawashima, M. Fujimura and S. Nakao (2005). “Characterization of the prostaglandin biosynthetic pathway in non-small cell lung cancer: a comparison with small cell lung cancer and correlation with angiogenesis, angiogenic factors and metastases.” Oncol Rep 13(6): 1049-1057.
    • (2005) Oncol Rep , vol.13 , Issue.6 , pp. 1049-1057
    • Yoshimoto, A.1    Kasahara, K.2    Kawashima, A.3    Fujimura, M.4    Nakao, S.5
  • 297
    • 0036480250 scopus 로고    scopus 로고
    • Thromboxane synthase inhibitors induce apoptosis in migration-arrested glioma cells
    • Yoshizato, K., S. Zapf, M. Westphal, M. E. Berens and A. Giese (2002). “Thromboxane synthase inhibitors induce apoptosis in migration-arrested glioma cells.” Neurosurgery 50(2): 343-354.
    • (2002) Neurosurgery , vol.50 , Issue.2 , pp. 343-354
    • Yoshizato, K.1    Zapf, S.2    Westphal, M.3    Berens, M.E.4    Giese, A.5
  • 298
    • 8544268688 scopus 로고    scopus 로고
    • Tumor-derived prostaglandin E2 and transforming growth factor-beta stimulate endothelial cell motility through inhibition of protein phosphatase-2A and involvement of PTEN and phosphatidylinositide 3-kinase
    • Young, M. R. (2004). “Tumor-derived prostaglandin E2 and transforming growth factor-beta stimulate endothelial cell motility through inhibition of protein phosphatase-2A and involvement of PTEN and phosphatidylinositide 3-kinase.” Angiogenesis 7(2): 123-131.
    • (2004) Angiogenesis , vol.7 , Issue.2 , pp. 123-131
    • Young, M.R.1
  • 299
    • 33644797877 scopus 로고    scopus 로고
    • Effects of curcumin on tumor angiogenesis and biomarkers, COX-2 and VEGF, in hepatocellular carcinoma cell-implanted nude mice
    • Yoysungnoen, P., P. Wirachwong, P. Bhattarakosol, H. Niimi and S. Patumraj (2006). “Effects of curcumin on tumor angiogenesis and biomarkers, COX-2 and VEGF, in hepatocellular carcinoma cell-implanted nude mice.” Clin Hemorheol Microcirc 34(1-2): 109-115.
    • (2006) Clin Hemorheol Microcirc , vol.34 , Issue.1-2 , pp. 109-115
    • Yoysungnoen, P.1    Wirachwong, P.2    Bhattarakosol, P.3    Niimi, H.4    Patumraj, S.5
  • 300
    • 79251543646 scopus 로고    scopus 로고
    • Resveratrol inhibits VEGF expression of human hepatocellular carcinoma cells through a NF-kappa B-mediated mechanism
    • Yu, H. B., H. F. Zhang, X. Zhang, D. Y. Li, H. Z. Xue, C. E. Pan and S. H. Zhao (2010). “Resveratrol inhibits VEGF expression of human hepatocellular carcinoma cells through a NF-kappa B-mediated mechanism.” Hepatogastroenterology 57(102-103): 1241-1246.
    • (2010) Hepatogastroenterology , vol.57 , Issue.102-103 , pp. 1241-1246
    • Yu, H.B.1    Zhang, H.F.2    Zhang, X.3    Li, D.Y.4    Xue, H.Z.5    Pan, C.E.6    Zhao, S.H.7
  • 301
    • 0041923845 scopus 로고    scopus 로고
    • The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase
    • Yu, Z., C. Schneider, W. E. Boeglin, L. J. Marnett and A. R. Brash (2003). “The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase.” Proc Natl Acad Sci USA 100(16): 9162-9167.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.16 , pp. 9162-9167
    • Yu, Z.1    Schneider, C.2    Boeglin, W.E.3    Marnett, L.J.4    Brash, A.R.5
  • 302
    • 49949098279 scopus 로고    scopus 로고
    • Effects of COX-2 inhibition on expression of vascular endothelial growth factor and interleukin-8 in lung cancer cells
    • Zhu, Y. M., N. S. Azahri, D. C. Yu and P. J. Woll (2008). “Effects of COX-2 inhibition on expression of vascular endothelial growth factor and interleukin-8 in lung cancer cells.” BMC Cancer 8: 218.
    • (2008) BMC Cancer , vol.8 , pp. 218
    • Zhu, Y.M.1    Azahri, N.S.2    Yu, D.C.3    Woll, P.J.4


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