Effect of COX-1 and COX-2 inhibition on induction and maintenance of carrageenan-evoked thermal hyperalgesia in rats

Journal of Pharmacology and Experimental Therapeutics

Volumn 285, Issue 3, 1998, Pages 1031-1038

  Dirig, David M ^b   Isakson, Peter C ^c   Yaksh, Tony L ^a,b  

^a University of California   (United States)

^b San Diego   (United States)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; CARRAGEENAN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; IBUPROFEN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROSTAGLANDIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; ENZYME INHIBITION; FACILITATION; HYPERALGESIA; INTRAPERITONEAL DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; LATENT PERIOD; MALE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; RAT; RECEPTOR INTRINSIC ACTIVITY; SUBCUTANEOUS DRUG ADMINISTRATION; THERMAL INJURY; TISSUE INJURY;

ANIMALS; CARRAGEENAN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; ENZYME REPRESSION; HEAT; HYPERALGESIA; IBUPROFEN; ISOENZYMES; MALE; MEMBRANE PROTEINS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0031808163     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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